# DREME 5.0.4 # command: dreme -oc StrongEnhancerVsSilencer -p strongEnhancer.fasta -n silencer.fasta -dna -eps -mink 6 -maxk 12 -e 0.05 # positives: 1051 from strongEnhancer.fasta (Tue Jul 28 11:35:47 CDT 2020) # negatives: 837 from silencer.fasta (Tue Jul 28 11:35:47 CDT 2020) # host: n171 # when: Tue Jul 28 11:40:48 CDT 2020 MEME version 5.0.4 ALPHABET "DNA" DNA-LIKE A "Adenine" CC0000 ~ T "Thymine" 008000 C "Cytosine" 0000CC ~ G "Guanine" FFB300 N "Any base" = ACGT X = ACGT . = ACGT V "Not T" = ACG H "Not G" = ACT D "Not C" = AGT B "Not A" = CGT M "Amino" = AC R "Purine" = AG W "Weak" = AT S "Strong" = CG Y "Pyrimidine" = CT K "Keto" = GT U = T END ALPHABET strands: + - Background letter frequencies (from dataset): A 0.248 C 0.260 G 0.236 T 0.256 MOTIF RGGKCA DREME-1 # Word RC Word Pos Neg P-value E-value # BEST RGGKCA TGMCCY 574 266 1.4e-023 7.4e-018 # AGGTCA TGACCT 248 100 3.3e-011 1.7e-005 # GGGTCA TGACCC 141 46 3.4e-009 1.8e-003 # GGGGCA TGCCCC 136 53 9.5e-007 4.9e-001 # AGGGCA TGCCCT 185 103 8.6e-004 4.5e+002 letter-probability matrix: alength= 4 w= 6 nsites= 773 E= 7.4e-018 0.614489 0.000000 0.385511 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.455369 0.544631 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 MOTIF CAKMTGG DREME-2 # Word RC Word Pos Neg P-value E-value # BEST CAKMTGG CCAKMTG 229 62 6.0e-019 2.9e-013 # CAGATGG CCATCTG 121 20 2.1e-015 1.1e-009 # CATCTGG CCAGATG 62 10 1.9e-008 9.6e-003 # CATATGG CCATATG 26 5 8.3e-004 4.1e+002 # CAGCTGG CCAGCTG 75 32 1.2e-003 5.9e+002 letter-probability matrix: alength= 4 w= 7 nsites= 253 E= 2.9e-013 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.707510 0.292490 0.509881 0.490119 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 MOTIF CCNCCCC DREME-3 # Word RC Word Pos Neg P-value E-value # BEST CCNCCCC GGGGNGG 272 102 3.3e-014 1.6e-008 # CCTCCCC GGGGAGG 129 41 8.8e-009 4.3e-003 # CCACCCC GGGGTGG 82 28 2.0e-005 9.7e+000 # CCGCCCC GGGGCGG 73 30 8.3e-004 4.0e+002 # CCCCCCC GGGGGGG 46 17 3.0e-003 1.5e+003 letter-probability matrix: alength= 4 w= 7 nsites= 361 E= 1.6e-008 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.229917 0.124654 0.238227 0.407202 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 MOTIF CWGCWG DREME-4 # Word RC Word Pos Neg P-value E-value # BEST CWGCWG CWGCWG 415 201 4.9e-013 2.3e-007 # CAGCAG CTGCTG 274 127 4.2e-009 2.0e-003 # CAGCTG CAGCTG 101 40 3.9e-005 1.8e+001 # CTGCAG CTGCAG 121 60 8.5e-004 4.0e+002 letter-probability matrix: alength= 4 w= 6 nsites= 521 E= 2.3e-007 0.000000 1.000000 0.000000 0.000000 0.476008 0.000000 0.000000 0.523992 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.508637 0.000000 0.000000 0.491363 0.000000 0.000000 1.000000 0.000000 MOTIF CAGSCTGY DREME-5 # Word RC Word Pos Neg P-value E-value # BEST CAGSCTGY RCAGSCTG 78 18 6.0e-008 2.7e-002 # CAGCCTGC GCAGGCTG 26 4 2.8e-004 1.3e+002 # CAGGCTGT ACAGCCTG 30 7 1.0e-003 4.6e+002 # CAGGCTGC GCAGCCTG 23 5 3.0e-003 1.3e+003 # CAGCCTGT ACAGGCTG 24 6 4.6e-003 2.1e+003 letter-probability matrix: alength= 4 w= 8 nsites= 85 E= 2.7e-002 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.470588 0.529412 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.494118 0.000000 0.505882 # Stopping reason: E-value threshold exceeded # Running time: 347.68 seconds