Datasetranaseq_carol_ns_sel_exprs.ranaseq_carol_ns_sel_phenotype.cls
#Fosl1_1_versus_Ctrl
Phenotyperanaseq_carol_ns_sel_phenotype.cls#Fosl1_1_versus_Ctrl
Upregulated in classCtrl
GeneSetSCHMITT_TNF_2020
Enrichment Score (ES)-0.51724255
Normalized Enrichment Score (NES)-1.7726138
Nominal p-value0.0
FDR q-value8.502024E-5
FWER p-Value0.001
Table: GSEA Results Summary



Fig 1: Enrichment plot: SCHMITT_TNF_2020   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL9A1COL9A13323.493-0.0015No
2GRB10GRB103902.7800.0069No
3NR4A3NR4A37211.858-0.0009No
4ATCAYATCAY7761.7790.0036No
5ROBO1ROBO17771.7780.0106No
6VWA1VWA18201.7030.0153No
7AGTAGT8501.6660.0205No
8NTN1NTN18651.6520.0264No
9SORBS1SORBS19011.6110.0311No
10PCDH1PCDH19151.5840.0367No
11RPGRRPGR9321.5610.0421No
12ENPP2ENPP210041.4730.0447No
13THY1THY111331.3430.0441No
14NRCAMNRCAM11471.3350.0487No
15RGS3RGS311721.3190.0528No
16ASPHD1ASPHD111741.3180.0580No
17LRRC4BLRRC4B12581.2490.0591No
18ZDHHC14ZDHHC1413151.2100.0613No
19FAM131BFAM131B13251.2040.0656No
20TMEM151BTMEM151B13691.1720.0682No
21FAM174BFAM174B14131.1500.0708No
22ARHGEF4ARHGEF414711.1260.0726No
23LIFRLIFR15181.0980.0748No
24SPARCL1SPARCL115881.0680.0758No
25BACE2BACE217140.9980.0740No
26GABRB3GABRB317490.9810.0763No
27CDH4CDH417680.9720.0793No
28APBA1APBA118410.9390.0797No
29PLATPLAT18950.9130.0809No
30PLLPPLLP20390.8450.0777No
31SYNGR3SYNGR324570.7230.0615No
32IFITM1IFITM125410.7030.0604No
33RHPN2RHPN225420.7030.0632No
34CABLES1CABLES125650.7020.0649No
35CITED1CITED125970.6920.0662No
36WIPF3WIPF327690.6560.0610No
37EBI3EBI327790.6540.0632No
38LAPTM5LAPTM530930.6310.0513No
39TRPM8TRPM831020.6310.0534No
40DPP4DPP433710.6020.0436No
41BMP5BMP537900.6020.0268No
42SLC16A9SLC16A938110.6020.0283No
43CERS1CERS139850.6020.0227No
44NPNTNPNT42190.5890.0144No
45DACT1DACT142230.5890.0166No
46TSC22D4TSC22D442520.5810.0176No
47HAS2HAS243130.5630.0170No
48PRICKLE1PRICKLE143140.5630.0193No
49GUCY1B1GUCY1B143430.5560.0202No
50ZIK1ZIK144580.5260.0170No
51KLHL5KLHL544700.5230.0186No
52ADAMTS9ADAMTS945830.4950.0154No
53FJX1FJX145860.4940.0172No
54PLEKHF1PLEKHF146210.4850.0176No
55TIFATIFA47540.4610.0134No
56TAF13TAF1347670.4590.0146No
57LRP2LRP250860.4080.0017No
58SEMA3BSEMA3B51800.394-0.0010No
59MGAT3MGAT352080.389-0.0007No
60PNKDPNKD54350.359-0.0096No
61NFKBIENFKBIE55680.339-0.0143No
62BIRC2BIRC257120.319-0.0196No
63RBM3RBM357370.317-0.0194No
64LIMD2LIMD258080.310-0.0214No
65CNTNAP1CNTNAP160370.282-0.0307No
66HIVEP1HIVEP161920.264-0.0367No
67ARHGEF40ARHGEF4062290.261-0.0374No
68TBC1D10ATBC1D10A63800.244-0.0432No
69MYO5BMYO5B64770.237-0.0467No
70PLEKHA4PLEKHA465190.233-0.0477No
71OSMROSMR65680.229-0.0490No
72PTP4A3PTP4A366290.222-0.0508No
73ARRDC4ARRDC467340.212-0.0547No
74NFKBIANFKBIA69920.191-0.0657No
75OSCP1OSCP170360.186-0.0670No
76PTX3PTX370740.183-0.0679No
77STOMSTOM71040.181-0.0686No
78VGFVGF73040.163-0.0770No
79IFNGR2IFNGR273690.158-0.0793No
80STAT3STAT373860.157-0.0794No
81TNIP2TNIP274020.155-0.0795No
82NFKBIZNFKBIZ75630.143-0.0862No
83PXDNPXDN78070.131-0.0968No
84SOD2SOD278530.129-0.0984No
85NDUFB8NDUFB883930.093-0.1226No
86EGR2EGR284670.089-0.1256No
87SNX10SNX1084940.087-0.1265No
88PRKAR1BPRKAR1B85120.086-0.1269No
89RAB31RAB3185350.084-0.1276No
90NR4A1NR4A187300.071-0.1362No
91ZSWIM4ZSWIM489340.057-0.1452No
92IRF3IRF389910.053-0.1476No
93ETV6ETV690130.052-0.1483No
94CDKAL1CDKAL192960.032-0.1611No
95KCNN4KCNN493160.031-0.1618No
96PSMD5PSMD594040.026-0.1657No
97PHF24PHF2497400.009-0.1810No
98IL4I1IL4I197640.009-0.1820No
99CD83CD8398430.007-0.1855No
100KLHL6KLHL699680.000-0.1912No
101PLPPR4PLPPR4100070.000-0.1929No
102SYT12SYT12101030.000-0.1973No
103MPZMPZ102330.000-0.2032No
104ETNK2ETNK2104690.000-0.2139No
105VAX1VAX1107850.000-0.2283No
106ARHGEF16ARHGEF16111210.000-0.2436No
107NFE2L3NFE2L3111540.000-0.2451No
108CYP1A1CYP1A1112460.000-0.2492No
109APOL6APOL6112710.000-0.2503No
110ICAM1ICAM1113380.000-0.2533No
111KREMEN2KREMEN2114100.000-0.2566No
112OSBPL5OSBPL513260-0.007-0.3410No
113RNF145RNF14513581-0.030-0.3555No
114NECTIN2NECTIN213793-0.046-0.3650No
115RAB13RAB1313913-0.054-0.3702No
116RAB35RAB3514065-0.065-0.3768No
117KLF10KLF1014253-0.079-0.3851No
118TRIM8TRIM814402-0.088-0.3915No
119MITD1MITD114514-0.096-0.3962No
120GCLMGCLM14515-0.096-0.3958No
121RNF19ARNF19A14596-0.104-0.3990No
122EFTUD2EFTUD214660-0.109-0.4015No
123RRASRRAS14715-0.113-0.4035No
124ACSL6ACSL614885-0.125-0.4108No
125NBL1NBL114933-0.127-0.4124No
126NCOA7NCOA714975-0.131-0.4138No
127ABRABR14989-0.132-0.4138No
128CYLDCYLD15176-0.147-0.4218No
129PLA2G4CPLA2G4C15261-0.155-0.4250No
130ANKRD33BANKRD33B15263-0.155-0.4244No
131ELL2ELL215283-0.157-0.4247No
132RESF1RESF115549-0.184-0.4361No
133F3F315573-0.188-0.4364No
134LRRN3LRRN315647-0.195-0.4389No
135MGAT4BMGAT4B15692-0.198-0.4402No
136BCL6BCL615742-0.205-0.4416No
137PGM2L1PGM2L115874-0.220-0.4467No
138CD63CD6315920-0.226-0.4479No
139IL6STIL6ST15946-0.228-0.4481No
140FZD8FZD816129-0.247-0.4555No
141TMEM158TMEM15816135-0.248-0.4547No
142ADAMTS1ADAMTS116243-0.261-0.4586No
143INSRINSR16258-0.262-0.4582No
144NFKB1NFKB116397-0.281-0.4634No
145IFNGR1IFNGR116406-0.282-0.4627No
146TAPBPTAPBP16464-0.291-0.4641No
147CAMK2DCAMK2D16528-0.301-0.4658No
148MAP3K11MAP3K1116590-0.311-0.4674No
149SFRP1SFRP116619-0.316-0.4674No
150OPTNOPTN16624-0.316-0.4664No
151SMOC2SMOC216658-0.322-0.4666No
152SLC35F6SLC35F616794-0.347-0.4714No
153WARSWARS16824-0.352-0.4714No
154ITGAVITGAV16885-0.361-0.4727No
155PEPDPEPD16916-0.366-0.4726No
156NUDT4NUDT416962-0.374-0.4732No
157WWTR1WWTR117052-0.391-0.4758No
158SQSTM1SQSTM117102-0.401-0.4764No
159S100A10S100A1017113-0.401-0.4753No
160SPRED3SPRED317123-0.403-0.4741No
161IL1RAPIL1RAP17145-0.407-0.4735No
162PODXLPODXL17226-0.422-0.4755No
163RIPK1RIPK117281-0.435-0.4762No
164SEMA4BSEMA4B17380-0.457-0.4789No
165CEMIP2CEMIP217382-0.458-0.4772No
166CAPN5CAPN517397-0.461-0.4760No
167TNFRSF1ATNFRSF1A17424-0.466-0.4754No
168NAMPTNAMPT17463-0.475-0.4752No
169UGCGUGCG17465-0.477-0.4734No
170CREB3CREB317466-0.477-0.4715No
171IRF1IRF117525-0.496-0.4722No
172FZD5FZD517563-0.505-0.4719No
173SOCS3SOCS317575-0.509-0.4704No
174RELBRELB17618-0.519-0.4703No
175GRWD1GRWD117648-0.531-0.4696No
176CSF1CSF117655-0.533-0.4678No
177RDH10RDH1017719-0.554-0.4685No
178DUSP5DUSP517740-0.564-0.4672No
179ALPK1ALPK117754-0.568-0.4655No
180B2MB2M17776-0.577-0.4642No
181SLC2A3SLC2A317819-0.591-0.4638No
182TNFRSF9TNFRSF917909-0.599-0.4655No
183VDRVDR18436-0.602-0.4872No
184CTSSCTSS18507-0.602-0.4880No
185EGFLAMEGFLAM18516-0.602-0.4860No
186ADAM19ADAM1918957-0.604-0.5038No
187ARL6IP5ARL6IP519004-0.619-0.5034No
188PTPREPTPRE19012-0.621-0.5013No
189C4AC4A19023-0.624-0.4993No
190ASB9ASB919116-0.630-0.5011No
191STAP2STAP219230-0.632-0.5037No
192PPP1R18PPP1R1819319-0.632-0.5053No
193SGK1SGK119582-0.680-0.5146Yes
194PDGFAPDGFA19619-0.685-0.5135Yes
195CITED4CITED419636-0.688-0.5116Yes
196FAM129AFAM129A19666-0.692-0.5102Yes
197ORAI1ORAI119681-0.697-0.5081Yes
198GFRA1GFRA119801-0.714-0.5107Yes
199ZFP36ZFP3619806-0.715-0.5081Yes
200RELL1RELL119837-0.732-0.5066Yes
201NAB2NAB219840-0.733-0.5038Yes
202TNFAIP3TNFAIP319849-0.737-0.5013Yes
203HMOX1HMOX119857-0.741-0.4987Yes
204VMP1VMP119880-0.754-0.4967Yes
205ADAMTS4ADAMTS419883-0.756-0.4938Yes
206CARSCARS19892-0.762-0.4912Yes
207TNCTNC19997-0.820-0.4927Yes
208IER2IER220032-0.844-0.4910Yes
209CRABP2CRABP220038-0.850-0.4879Yes
210A2MA2M20053-0.858-0.4851Yes
211L1CAML1CAM20076-0.874-0.4827Yes
212RIOX2RIOX220095-0.886-0.4801Yes
213PMP22PMP2220136-0.915-0.4783Yes
214JCADJCAD20142-0.916-0.4749Yes
215FOSL2FOSL220154-0.923-0.4718Yes
216PGBD5PGBD520211-0.958-0.4706Yes
217DUSP6DUSP620231-0.966-0.4677Yes
218SH2B3SH2B320275-0.993-0.4657Yes
219LPGAT1LPGAT120314-1.022-0.4635Yes
220ISG20ISG2020319-1.025-0.4596Yes
221CDKN1ACDKN1A20334-1.035-0.4562Yes
222KLF5KLF520369-1.057-0.4536Yes
223NFKB2NFKB220422-1.090-0.4517Yes
224MICALL2MICALL220439-1.100-0.4481Yes
225LGALS1LGALS120466-1.122-0.4449Yes
226CD44CD4420484-1.138-0.4412Yes
227IFIH1IFIH120489-1.142-0.4369Yes
228IRAK2IRAK220518-1.156-0.4336Yes
229BATF3BATF320525-1.162-0.4294Yes
230JUNBJUNB20559-1.193-0.4262Yes
231CEBPBCEBPB20573-1.206-0.4220Yes
232CSRNP1CSRNP120633-1.244-0.4199Yes
233CDKN2BCDKN2B20635-1.246-0.4150Yes
234ERAP1ERAP120645-1.256-0.4105Yes
235SERTAD1SERTAD120654-1.268-0.4059Yes
236EMP1EMP120675-1.290-0.4017Yes
237EMILIN1EMILIN120686-1.301-0.3971Yes
238GAP43GAP4320696-1.306-0.3924Yes
239CSRP2CSRP220706-1.319-0.3876Yes
240FGF2FGF220771-1.362-0.3852Yes
241NRG1NRG120780-1.369-0.3802Yes
242PDGFRLPDGFRL20822-1.421-0.3765Yes
243BCL3BCL320841-1.433-0.3717Yes
244CXCL10CXCL1020842-1.433-0.3660Yes
245NUAK2NUAK220847-1.435-0.3606Yes
246TAGLN2TAGLN220860-1.446-0.3554Yes
247IER3IER320879-1.462-0.3505Yes
248BMP2BMP220892-1.469-0.3453Yes
249IGFBP3IGFBP320978-1.584-0.3430Yes
250SYNPOSYNPO20979-1.585-0.3368Yes
251MAOBMAOB20984-1.598-0.3307Yes
252LIFLIF21001-1.620-0.3250Yes
253TIMP1TIMP121019-1.640-0.3194Yes
254MATN2MATN221088-1.736-0.3157Yes
255DRAM1DRAM121092-1.743-0.3090Yes
256SPSB1SPSB121149-1.811-0.3044Yes
257ALPLALPL21154-1.823-0.2974Yes
258SDC4SDC421156-1.825-0.2903Yes
259TMEM173TMEM17321215-1.892-0.2855Yes
260FAM43AFAM43A21225-1.908-0.2785Yes
261DTX3LDTX3L21258-1.965-0.2722Yes
262AHNAK2AHNAK221336-2.071-0.2676Yes
263PIK3CDPIK3CD21350-2.088-0.2600Yes
264RASEFRASEF21382-2.148-0.2530Yes
265TGFB1TGFB121432-2.224-0.2465Yes
266SERPINE1SERPINE121444-2.262-0.2381Yes
267CDC42EP5CDC42EP521454-2.290-0.2295Yes
268TNFRSF12ATNFRSF12A21458-2.302-0.2206Yes
269SPP1SPP121467-2.320-0.2119Yes
270EMP3EMP321469-2.325-0.2028Yes
271ANXA1ANXA121470-2.327-0.1937Yes
272FADS3FADS321473-2.332-0.1846Yes
273LARP6LARP621510-2.448-0.1766Yes
274PERPPERP21556-2.592-0.1685Yes
275RGS16RGS1621614-2.607-0.1609Yes
276SLC16A3SLC16A321618-2.631-0.1507Yes
277ARNTL2ARNTL221640-2.721-0.1410Yes
278DOC2BDOC2B21645-2.752-0.1303Yes
279TRAF1TRAF121676-2.868-0.1205Yes
280PLCD3PLCD321731-2.965-0.1113Yes
281AHRAHR21751-3.049-0.1002Yes
282PLAUPLAU21807-3.644-0.0884Yes
283PARP9PARP921822-3.803-0.0741Yes
284LHX9LHX921826-3.827-0.0592Yes
285ADAMTS14ADAMTS1421835-4.110-0.0434Yes
286EMILIN2EMILIN221967-5.000-0.0298Yes
287SGPP2SGPP222000-5.000-0.0116Yes
288LOXL2LOXL222003-5.0000.0079Yes
Table: GSEA details [plain text format]



Fig 2: SCHMITT_TNF_2020   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SCHMITT_TNF_2020: Random ES distribution   
Gene set null distribution of ES for SCHMITT_TNF_2020