Details for gene set VERHAAK_MES

Table: GSEA Results Summary

Dataset	NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl_repos
Phenotype	NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	VERHAAK_MES_2010
Enrichment Score (ES)	-0.4938699
Normalized Enrichment Score (NES)	-1.3236738
Nominal p-value	0.07526882
FDR q-value	0.1591419
FWER p-Value	0.628

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LCP2	LCP2	87	0.886	0.0171	No
2	CASP4	CASP4	204	0.693	0.0285	No
3	HK3	HK3	254	0.617	0.0409	No
4	CCR5	CCR5	384	0.582	0.0491	No
5	TRIM38	TRIM38	474	0.539	0.0581	No
6	CASP1	CASP1	480	0.536	0.0704	No
7	VDR	VDR	484	0.533	0.0827	No
8	CD14	CD14	684	0.440	0.0848	No
9	SRPX2	SRPX2	724	0.434	0.0933	No
10	FOLR2	FOLR2	752	0.430	0.1022	No
11	KYNU	KYNU	837	0.419	0.1085	No
12	GNA15	GNA15	872	0.416	0.1169	No
13	DAB2	DAB2	1160	0.365	0.1135	No
14	MAFB	MAFB	1188	0.358	0.1208	No
15	CYBRD1	CYBRD1	1216	0.351	0.1279	No
16	CCDC109B	CCDC109B	1459	0.295	0.1248	No
17	SLAMF8	SLAMF8	1485	0.290	0.1305	No
18	THBS1	THBS1	1605	0.272	0.1319	No
19	ITGA4	ITGA4	1760	0.254	0.1315	No
20	NCF4	NCF4	2232	0.245	0.1178	No
21	LAPTM5	LAPTM5	2742	0.215	0.1018	No
22	TNFAIP3	TNFAIP3	2772	0.211	0.1055	No
23	PTPN6	PTPN6	2801	0.207	0.1092	No
24	FCGR2B	FCGR2B	2808	0.206	0.1137	No
25	PLAU	PLAU	2866	0.199	0.1160	No
26	RELB	RELB	3268	0.161	0.1032	No
27	VAMP5	VAMP5	3432	0.147	0.0999	No
28	TIMP1	TIMP1	3528	0.139	0.0992	No
29	CTSC	CTSC	3655	0.131	0.0971	No
30	ACPP	ACPP	3683	0.129	0.0990	No
31	THBD	THBD	3821	0.119	0.0961	No
32	RRAS	RRAS	4145	0.105	0.0852	No
33	SLC16A3	SLC16A3	4187	0.103	0.0859	No
34	TRPM2	TRPM2	4323	0.097	0.0826	No
35	TNFAIP8	TNFAIP8	4331	0.096	0.0846	No
36	CASP8	CASP8	4344	0.096	0.0863	No
37	TLR2	TLR2	4459	0.090	0.0837	No
38	POLD4	POLD4	4652	0.083	0.0777	No
39	TNFRSF11A	TNFRSF11A	4792	0.078	0.0738	No
40	FHOD1	FHOD1	4903	0.075	0.0710	No
41	RHOG	RHOG	5042	0.071	0.0670	No
42	TRADD	TRADD	5278	0.065	0.0588	No
43	ASL	ASL	5355	0.063	0.0571	No
44	STXBP2	STXBP2	5402	0.062	0.0566	No
45	MVP	MVP	5446	0.061	0.0563	No
46	ALDH3B1	ALDH3B1	5542	0.059	0.0538	No
47	ADAM12	ADAM12	5685	0.056	0.0492	No
48	IL15RA	IL15RA	5720	0.056	0.0491	No
49	SFT2D2	SFT2D2	6048	0.050	0.0368	No
50	CDCP1	CDCP1	6176	0.048	0.0326	No
51	CEBPB	CEBPB	6185	0.048	0.0334	No
52	CD4	CD4	6299	0.046	0.0298	No
53	CTSZ	CTSZ	6378	0.044	0.0276	No
54	PIGP	PIGP	6538	0.042	0.0220	No
55	ELF4	ELF4	6733	0.039	0.0149	No
56	TNFRSF1A	TNFRSF1A	6759	0.039	0.0148	No
57	LTBP2	LTBP2	6925	0.036	0.0088	No
58	ITGA5	ITGA5	6940	0.036	0.0091	No
59	SEC24D	SEC24D	7396	0.031	-0.0090	No
60	BLVRB	BLVRB	7872	0.025	-0.0280	No
61	PYGL	PYGL	8749	0.017	-0.0638	No
62	YAP1	YAP1	8771	0.016	-0.0643	No
63	PLS3	PLS3	9369	0.011	-0.0887	No
64	ANXA1	ANXA1	10276	0.003	-0.1261	No
65	TGOLN2	TGOLN2	14483	0.000	-0.2998	No
66	SYNGR2	SYNGR2	15178	-0.003	-0.3284	No
67	UAP1	UAP1	15225	-0.004	-0.3303	No
68	UCP2	UCP2	15270	-0.004	-0.3320	No
69	RABGAP1L	RABGAP1L	15310	-0.004	-0.3335	No
70	DSC2	DSC2	15482	-0.006	-0.3404	No
71	FNDC3B	FNDC3B	15538	-0.006	-0.3426	No
72	ARPC1B	ARPC1B	15616	-0.007	-0.3456	No
73	EFEMP2	EFEMP2	15731	-0.008	-0.3501	No
74	SERPINE1	SERPINE1	15830	-0.009	-0.3539	No
75	DCBLD2	DCBLD2	15941	-0.010	-0.3583	No
76	HEXA	HEXA	16046	-0.011	-0.3623	No
77	HEXB	HEXB	16429	-0.015	-0.3777	No
78	S100A13	S100A13	16435	-0.015	-0.3776	No
79	RBMS1	RBMS1	16641	-0.017	-0.3857	No
80	SLC11A1	SLC11A1	16688	-0.017	-0.3872	No
81	EMP3	EMP3	16762	-0.018	-0.3897	No
82	PTPN22	PTPN22	17005	-0.021	-0.3992	No
83	TCIRG1	TCIRG1	17040	-0.021	-0.4002	No
84	LRRFIP1	LRRFIP1	17105	-0.022	-0.4023	No
85	DOK3	DOK3	17219	-0.024	-0.4064	No
86	CTSB	CTSB	17332	-0.025	-0.4104	No
87	LTBP1	LTBP1	17471	-0.027	-0.4155	No
88	IFI30	IFI30	17476	-0.027	-0.4150	No
89	SWAP70	SWAP70	17580	-0.028	-0.4186	No
90	MGAT1	MGAT1	17682	-0.030	-0.4221	No
91	NPC2	NPC2	17773	-0.031	-0.4251	No
92	TMBIM1	TMBIM1	17856	-0.032	-0.4278	No
93	TEC	TEC	17977	-0.034	-0.4319	No
94	WWTR1	WWTR1	18020	-0.035	-0.4328	No
95	CLIC1	CLIC1	18140	-0.037	-0.4369	No
96	SCPEP1	SCPEP1	18472	-0.043	-0.4496	No
97	IQGAP1	IQGAP1	18498	-0.043	-0.4496	No
98	CD2AP	CD2AP	18633	-0.046	-0.4540	No
99	HFE	HFE	18708	-0.048	-0.4560	No
100	MAN2A1	MAN2A1	18907	-0.053	-0.4629	No
101	LGALS1	LGALS1	18926	-0.053	-0.4624	No
102	MFSD1	MFSD1	19110	-0.058	-0.4686	No
103	NRP1	NRP1	19122	-0.059	-0.4677	No
104	WIPF1	WIPF1	19239	-0.063	-0.4710	No
105	AMPD3	AMPD3	19418	-0.069	-0.4768	No
106	IGFBP6	IGFBP6	19469	-0.071	-0.4772	No
107	GRN	GRN	19573	-0.074	-0.4797	No
108	TLR4	TLR4	19589	-0.075	-0.4786	No
109	COL8A2	COL8A2	19604	-0.076	-0.4774	No
110	LY96	LY96	19617	-0.076	-0.4761	No
111	MAN2B1	MAN2B1	19621	-0.076	-0.4744	No
112	FURIN	FURIN	19684	-0.079	-0.4752	No
113	DSE	DSE	19781	-0.083	-0.4772	No
114	SAT1	SAT1	19808	-0.084	-0.4763	No
115	RAB27A	RAB27A	19809	-0.084	-0.4743	No
116	COPZ2	COPZ2	20125	-0.100	-0.4850	No
117	ANXA4	ANXA4	20186	-0.103	-0.4851	No
118	ITGB2	ITGB2	20333	-0.108	-0.4886	No
119	STAT6	STAT6	20462	-0.115	-0.4912	Yes
120	RBKS	RBKS	20507	-0.117	-0.4903	Yes
121	RAB32	RAB32	20529	-0.119	-0.4883	Yes
122	MYH9	MYH9	20636	-0.124	-0.4898	Yes
123	COL1A1	COL1A1	20681	-0.127	-0.4887	Yes
124	COL5A1	COL5A1	20683	-0.127	-0.4857	Yes
125	ACSL1	ACSL1	20761	-0.131	-0.4858	Yes
126	ENG	ENG	20788	-0.133	-0.4838	Yes
127	NCF2	NCF2	20814	-0.134	-0.4817	Yes
128	SQRDL	SQRDL	20995	-0.151	-0.4856	Yes
129	PLK3	PLK3	21148	-0.165	-0.4880	Yes
130	MRC2	MRC2	21173	-0.168	-0.4851	Yes
131	EHD2	EHD2	21204	-0.171	-0.4824	Yes
132	TGFBR2	TGFBR2	21354	-0.188	-0.4841	Yes
133	CAST	CAST	21363	-0.190	-0.4800	Yes
134	LAMB1	LAMB1	21416	-0.195	-0.4776	Yes
135	IL1R1	IL1R1	21433	-0.197	-0.4737	Yes
136	SH2B3	SH2B3	21658	-0.219	-0.4778	Yes
137	FMNL1	FMNL1	21696	-0.223	-0.4741	Yes
138	PTPRC	PTPRC	21711	-0.226	-0.4694	Yes
139	SHC1	SHC1	21741	-0.230	-0.4653	Yes
140	TNFRSF1B	TNFRSF1B	21769	-0.234	-0.4609	Yes
141	SLC10A3	SLC10A3	21813	-0.241	-0.4571	Yes
142	LHFPL2	LHFPL2	21860	-0.248	-0.4532	Yes
143	ARHGAP29	ARHGAP29	21898	-0.254	-0.4488	Yes
144	P4HA2	P4HA2	22070	-0.281	-0.4493	Yes
145	RUNX2	RUNX2	22102	-0.286	-0.4439	Yes
146	RAB11FIP1	RAB11FIP1	22112	-0.287	-0.4375	Yes
147	RAC2	RAC2	22161	-0.295	-0.4326	Yes
148	LCP1	LCP1	22265	-0.313	-0.4296	Yes
149	PROCR	PROCR	22311	-0.323	-0.4239	Yes
150	PTGER4	PTGER4	22332	-0.329	-0.4170	Yes
151	ANXA2	ANXA2	22374	-0.334	-0.4109	Yes
152	COL1A2	COL1A2	22387	-0.337	-0.4035	Yes
153	LGALS3	LGALS3	22395	-0.340	-0.3959	Yes
154	CNN2	CNN2	22435	-0.347	-0.3894	Yes
155	C5AR1	C5AR1	22491	-0.352	-0.3834	Yes
156	BATF	BATF	22921	-0.358	-0.3928	Yes
157	MYO1F	MYO1F	23021	-0.366	-0.3883	Yes
158	MSR1	MSR1	23060	-0.373	-0.3812	Yes
159	STAB1	STAB1	23094	-0.379	-0.3737	Yes
160	LY75	LY75	23111	-0.385	-0.3654	Yes
161	MGST2	MGST2	23149	-0.394	-0.3577	Yes
162	PLAUR	PLAUR	23251	-0.408	-0.3524	Yes
163	LAIR1	LAIR1	23256	-0.409	-0.3430	Yes
164	S100A4	S100A4	23442	-0.464	-0.3398	Yes
165	ST14	ST14	23465	-0.472	-0.3296	Yes
166	NOD2	NOD2	23475	-0.474	-0.3189	Yes
167	PTRF	PTRF	23482	-0.476	-0.3081	Yes
168	S100A11	S100A11	23510	-0.487	-0.2978	Yes
169	ALOX5	ALOX5	23563	-0.510	-0.2880	Yes
170	PDPN	PDPN	23644	-0.542	-0.2787	Yes
171	BDKRB2	BDKRB2	23649	-0.544	-0.2661	Yes
172	GCNT1	GCNT1	23676	-0.557	-0.2542	Yes
173	SP100	SP100	23768	-0.624	-0.2434	Yes
174	AIM1	AIM1	23776	-0.633	-0.2289	Yes
175	ITGAM	ITGAM	23961	-0.701	-0.2201	Yes
176	FES	FES	23965	-0.703	-0.2038	Yes
177	CLCF1	CLCF1	24034	-0.767	-0.1887	Yes
178	TGFBI	TGFBI	24073	-0.818	-0.1711	Yes
179	ARSJ	ARSJ	24152	-0.971	-0.1517	Yes
180	TES	TES	24165	-1.003	-0.1287	Yes
181	BNC2	BNC2	24170	-1.012	-0.1053	Yes
182	LOX	LOX	24181	-1.034	-0.0815	Yes
183	MAPK13	MAPK13	24194	-1.059	-0.0573	Yes
184	FHL2	FHL2	24205	-1.090	-0.0322	Yes
185	FXYD5	FXYD5	24345	-1.702	0.0018	Yes