Details for gene set SCHMITT_TNF

Table: GSEA Results Summary

Dataset	NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl_repos
Phenotype	NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	SCHMITT_TNF_2020
Enrichment Score (ES)	-0.4104595
Normalized Enrichment Score (NES)	-1.3235664
Nominal p-value	0.07231405
FDR q-value	0.14713097
FWER p-Value	0.628

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRR16	PRR16	116	0.807	0.0119	No
2	BCL3	BCL3	167	0.756	0.0255	No
3	STAP2	STAP2	178	0.729	0.0402	No
4	VDR	VDR	484	0.533	0.0386	No
5	KCNN4	KCNN4	487	0.528	0.0495	No
6	ICAM1	ICAM1	511	0.517	0.0593	No
7	KLHL6	KLHL6	633	0.462	0.0638	No
8	LIF	LIF	668	0.445	0.0717	No
9	DRAM1	DRAM1	718	0.434	0.0787	No
10	NFKBIE	NFKBIE	939	0.413	0.0781	No
11	HAS2	HAS2	1015	0.408	0.0835	No
12	ENPP2	ENPP2	1225	0.348	0.0820	No
13	VWA1	VWA1	1299	0.329	0.0858	No
14	OSMR	OSMR	1318	0.324	0.0918	No
15	TMEM151B	TMEM151B	1344	0.318	0.0973	No
16	BATF3	BATF3	1347	0.316	0.1038	No
17	MYO5B	MYO5B	1349	0.316	0.1103	No
18	ANO9	ANO9	1383	0.309	0.1154	No
19	SOCS3	SOCS3	1528	0.284	0.1153	No
20	JUNB	JUNB	2433	0.243	0.0828	No
21	NFE2L3	NFE2L3	2596	0.236	0.0810	No
22	KREMEN2	KREMEN2	2640	0.231	0.0840	No
23	LAPTM5	LAPTM5	2742	0.215	0.0842	No
24	TNFAIP3	TNFAIP3	2772	0.211	0.0874	No
25	IRAK2	IRAK2	2789	0.209	0.0911	No
26	PLAU	PLAU	2866	0.199	0.0921	No
27	APOL6	APOL6	2872	0.198	0.0960	No
28	FAM174B	FAM174B	2941	0.191	0.0971	No
29	NFKBIZ	NFKBIZ	2952	0.189	0.1006	No
30	PLLP	PLLP	3009	0.184	0.1021	No
31	THY1	THY1	3146	0.171	0.1000	No
32	NR4A1	NR4A1	3163	0.170	0.1029	No
33	ALPK1	ALPK1	3199	0.167	0.1049	No
34	DPP4	DPP4	3244	0.163	0.1065	No
35	WIPF3	WIPF3	3256	0.162	0.1094	No
36	RELB	RELB	3268	0.161	0.1122	No
37	EBI3	EBI3	3301	0.159	0.1142	No
38	PTP4A3	PTP4A3	3444	0.145	0.1113	No
39	ZFP36	ZFP36	3467	0.143	0.1134	No
40	TIMP1	TIMP1	3528	0.139	0.1138	No
41	NFKB2	NFKB2	3730	0.126	0.1081	No
42	COL9A1	COL9A1	3745	0.124	0.1101	No
43	ZDHHC14	ZDHHC14	3790	0.121	0.1107	No
44	ADAMTS1	ADAMTS1	3813	0.120	0.1123	No
45	CABLES1	CABLES1	3913	0.115	0.1106	No
46	DUSP5	DUSP5	3914	0.115	0.1130	No
47	ROBO1	ROBO1	3970	0.112	0.1130	No
48	TIFA	TIFA	4022	0.111	0.1132	No
49	PRKAR1B	PRKAR1B	4072	0.108	0.1134	No
50	LIFR	LIFR	4103	0.106	0.1144	No
51	RRAS	RRAS	4145	0.105	0.1149	No
52	SLC16A3	SLC16A3	4187	0.103	0.1153	No
53	PLEKHF1	PLEKHF1	4218	0.102	0.1162	No
54	IL27RA	IL27RA	4258	0.100	0.1166	No
55	GABRB3	GABRB3	4414	0.093	0.1121	No
56	SEMA3B	SEMA3B	4424	0.092	0.1136	No
57	C4A	C4A	4520	0.088	0.1115	No
58	BIRC2	BIRC2	4593	0.085	0.1103	No
59	SORBS1	SORBS1	4601	0.084	0.1117	No
60	CNTNAP1	CNTNAP1	4644	0.083	0.1117	No
61	GRB10	GRB10	4738	0.080	0.1095	No
62	STAT3	STAT3	4744	0.080	0.1110	No
63	RASEF	RASEF	4853	0.076	0.1081	No
64	NRCAM	NRCAM	4924	0.075	0.1067	No
65	PIK3CD	PIK3CD	4946	0.074	0.1074	No
66	IFNGR2	IFNGR2	4973	0.073	0.1078	No
67	NFKBIA	NFKBIA	5028	0.072	0.1071	No
68	CITED1	CITED1	5116	0.069	0.1049	No
69	MPZ	MPZ	5142	0.069	0.1053	No
70	LRRC4B	LRRC4B	5250	0.066	0.1022	No
71	F3	F3	5284	0.065	0.1022	No
72	GAP43	GAP43	5306	0.064	0.1026	No
73	APBA1	APBA1	5397	0.062	0.1002	No
74	ARHGEF40	ARHGEF40	5438	0.062	0.0998	No
75	KLHL5	KLHL5	5452	0.061	0.1005	No
76	ALPL	ALPL	5529	0.059	0.0986	No
77	RAB13	RAB13	5563	0.059	0.0985	No
78	RNF19A	RNF19A	5772	0.054	0.0910	No
79	ETV6	ETV6	5802	0.054	0.0909	No
80	LIMD2	LIMD2	5927	0.052	0.0868	No
81	EGR2	EGR2	6070	0.049	0.0819	No
82	PDGFA	PDGFA	6104	0.049	0.0816	No
83	BCL6	BCL6	6184	0.048	0.0793	No
84	CEBPB	CEBPB	6185	0.048	0.0803	No
85	AGT	AGT	6195	0.047	0.0809	No
86	PLEKHA4	PLEKHA4	6320	0.045	0.0767	No
87	LOXL2	LOXL2	6389	0.044	0.0748	No
88	TNIP2	TNIP2	6402	0.044	0.0752	No
89	ZIK1	ZIK1	6426	0.043	0.0751	No
90	SLC16A9	SLC16A9	6530	0.042	0.0717	No
91	IER2	IER2	6568	0.041	0.0711	No
92	CDH4	CDH4	6583	0.041	0.0713	No
93	TAF13	TAF13	6638	0.040	0.0699	No
94	TNFRSF1A	TNFRSF1A	6759	0.039	0.0658	No
95	PCDH1	PCDH1	6804	0.038	0.0647	No
96	CXCL10	CXCL10	6851	0.037	0.0636	No
97	ACSL6	ACSL6	6868	0.037	0.0637	No
98	ORAI1	ORAI1	6920	0.036	0.0623	No
99	TBC1D10A	TBC1D10A	7232	0.033	0.0501	No
100	NPNT	NPNT	7429	0.030	0.0426	No
101	IRF1	IRF1	7515	0.029	0.0397	No
102	FJX1	FJX1	7533	0.029	0.0396	No
103	PLA2G4C	PLA2G4C	7624	0.028	0.0365	No
104	TSC22D4	TSC22D4	7627	0.028	0.0369	No
105	SYNGR3	SYNGR3	7655	0.028	0.0364	No
106	RBM3	RBM3	7727	0.027	0.0340	No
107	PNKD	PNKD	7771	0.027	0.0328	No
108	ARRDC4	ARRDC4	7879	0.025	0.0289	No
109	CSF1	CSF1	7934	0.025	0.0271	No
110	ZSWIM4	ZSWIM4	7955	0.024	0.0268	No
111	SPRED3	SPRED3	8190	0.022	0.0176	No
112	KLF10	KLF10	8197	0.022	0.0178	No
113	RNF145	RNF145	8303	0.021	0.0138	No
114	TGFB1	TGFB1	8447	0.019	0.0083	No
115	RGS3	RGS3	8720	0.017	-0.0026	No
116	S100A10	S100A10	8879	0.015	-0.0089	No
117	NFKB1	NFKB1	8993	0.014	-0.0133	No
118	ARNTL2	ARNTL2	9035	0.014	-0.0147	No
119	NDUFB8	NDUFB8	9097	0.013	-0.0169	No
120	RPGR	RPGR	9152	0.013	-0.0189	No
121	ITGAV	ITGAV	9156	0.013	-0.0188	No
122	PGBD5	PGBD5	9287	0.012	-0.0239	No
123	EFTUD2	EFTUD2	9320	0.011	-0.0250	No
124	TAGLN2	TAGLN2	9367	0.011	-0.0267	No
125	ANKRD33B	ANKRD33B	9552	0.009	-0.0341	No
126	ADAMTS4	ADAMTS4	9630	0.009	-0.0371	No
127	ATCAY	ATCAY	9761	0.007	-0.0424	No
128	IRF3	IRF3	9844	0.007	-0.0456	No
129	CDKAL1	CDKAL1	9956	0.006	-0.0501	No
130	ANXA1	ANXA1	10276	0.003	-0.0633	No
131	PMP22	PMP22	10332	0.003	-0.0655	No
132	NTN1	NTN1	10431	0.002	-0.0696	No
133	IFNGR1	IFNGR1	10479	0.001	-0.0715	No
134	PTX3	PTX3	10494	0.001	-0.0720	No
135	MGAT3	MGAT3	10570	0.001	-0.0751	No
136	CYLD	CYLD	10624	0.000	-0.0773	No
137	CERS1	CERS1	12141	0.000	-0.1402	No
138	GTSF1	GTSF1	12935	0.000	-0.1731	No
139	SOD2	SOD2	14901	-0.001	-0.2547	No
140	PLCD3	PLCD3	15085	-0.002	-0.2622	No
141	HIVEP1	HIVEP1	15161	-0.003	-0.2653	No
142	MAP3K11	MAP3K11	15189	-0.003	-0.2663	No
143	NCOA7	NCOA7	15197	-0.003	-0.2665	No
144	CSRNP1	CSRNP1	15415	-0.005	-0.2754	No
145	TMEM158	TMEM158	15473	-0.006	-0.2777	No
146	ELL2	ELL2	15622	-0.007	-0.2837	No
147	BMP2	BMP2	15635	-0.007	-0.2840	No
148	ARHGEF4	ARHGEF4	15686	-0.008	-0.2859	No
149	SERPINE1	SERPINE1	15830	-0.009	-0.2917	No
150	ADAM19	ADAM19	15961	-0.010	-0.2969	No
151	GCLM	GCLM	15976	-0.010	-0.2972	No
152	MGAT4B	MGAT4B	16035	-0.011	-0.2994	No
153	ARL6IP5	ARL6IP5	16052	-0.011	-0.2998	No
154	RIPK1	RIPK1	16076	-0.011	-0.3006	No
155	IL6ST	IL6ST	16292	-0.014	-0.3092	No
156	ADAMTS9	ADAMTS9	16408	-0.015	-0.3137	No
157	SEMA4B	SEMA4B	16590	-0.016	-0.3208	No
158	SLC35F6	SLC35F6	16714	-0.018	-0.3256	No
159	EMP3	EMP3	16762	-0.018	-0.3272	No
160	OSBPL5	OSBPL5	16764	-0.018	-0.3268	No
161	RDH10	RDH10	16938	-0.020	-0.3336	No
162	SPARCL1	SPARCL1	16951	-0.021	-0.3336	No
163	CD63	CD63	17076	-0.022	-0.3383	No
164	HMOX1	HMOX1	17226	-0.024	-0.3440	No
165	MATN2	MATN2	17308	-0.025	-0.3469	No
166	VMP1	VMP1	17464	-0.027	-0.3527	No
167	RAB35	RAB35	17508	-0.027	-0.3540	No
168	GRWD1	GRWD1	17672	-0.030	-0.3601	No
169	SGK1	SGK1	17712	-0.030	-0.3611	No
170	TRIM8	TRIM8	17765	-0.031	-0.3626	No
171	INSR	INSR	17870	-0.032	-0.3663	No
172	RHPN2	RHPN2	17908	-0.033	-0.3671	No
173	TMEM173	TMEM173	17927	-0.033	-0.3672	No
174	SFRP1	SFRP1	17944	-0.034	-0.3671	No
175	WWTR1	WWTR1	18020	-0.035	-0.3695	No
176	CREB3	CREB3	18203	-0.038	-0.3763	No
177	OSCP1	OSCP1	18289	-0.040	-0.3790	No
178	SNX10	SNX10	18335	-0.040	-0.3800	No
179	PSMD5	PSMD5	18387	-0.041	-0.3813	No
180	TRAF1	TRAF1	18411	-0.042	-0.3814	No
181	IFITM1	IFITM1	18435	-0.042	-0.3814	No
182	PLAT	PLAT	18557	-0.045	-0.3855	No
183	SMOC2	SMOC2	18570	-0.045	-0.3851	No
184	CARS	CARS	18644	-0.047	-0.3872	No
185	PDGFRL	PDGFRL	18743	-0.049	-0.3902	No
186	DUSP6	DUSP6	18759	-0.049	-0.3898	No
187	PRICKLE1	PRICKLE1	18766	-0.050	-0.3890	No
188	UGCG	UGCG	18841	-0.051	-0.3910	No
189	LGALS1	LGALS1	18926	-0.053	-0.3934	No
190	OPTN	OPTN	19056	-0.057	-0.3976	No
191	PEPD	PEPD	19059	-0.057	-0.3965	No
192	NUAK2	NUAK2	19150	-0.060	-0.3990	No
193	FOSL2	FOSL2	19180	-0.061	-0.3989	No
194	ERAP1	ERAP1	19253	-0.063	-0.4006	No
195	EMILIN1	EMILIN1	19277	-0.064	-0.4002	No
196	RAB31	RAB31	19332	-0.066	-0.4011	No
197	VAX1	VAX1	19421	-0.069	-0.4033	No
198	KLF5	KLF5	19442	-0.070	-0.4027	No
199	MITD1	MITD1	19528	-0.073	-0.4047	No
200	B2M	B2M	19601	-0.075	-0.4061	No
201	NAMPT	NAMPT	19644	-0.077	-0.4063	No
202	RELL1	RELL1	19671	-0.078	-0.4057	No
203	TAPBP	TAPBP	19699	-0.079	-0.4052	No
204	CDKN1A	CDKN1A	19702	-0.080	-0.4036	No
205	PXDN	PXDN	19712	-0.080	-0.4024	No
206	CRABP2	CRABP2	19907	-0.089	-0.4086	No
207	CD44	CD44	19954	-0.091	-0.4086	Yes
208	TNC	TNC	19967	-0.092	-0.4072	Yes
209	LPGAT1	LPGAT1	19980	-0.093	-0.4057	Yes
210	SERTAD1	SERTAD1	19991	-0.093	-0.4042	Yes
211	WARS	WARS	19999	-0.094	-0.4026	Yes
212	PPP1R18	PPP1R18	20006	-0.094	-0.4009	Yes
213	PODXL	PODXL	20071	-0.097	-0.4015	Yes
214	SQSTM1	SQSTM1	20077	-0.098	-0.3997	Yes
215	FAM43A	FAM43A	20087	-0.098	-0.3980	Yes
216	IER3	IER3	20182	-0.102	-0.3998	Yes
217	NBL1	NBL1	20197	-0.103	-0.3982	Yes
218	ABR	ABR	20266	-0.105	-0.3989	Yes
219	NUDT4	NUDT4	20283	-0.106	-0.3973	Yes
220	CLDN4	CLDN4	20291	-0.107	-0.3954	Yes
221	FZD8	FZD8	20308	-0.107	-0.3939	Yes
222	FAM131B	FAM131B	20375	-0.111	-0.3943	Yes
223	SYT12	SYT12	20616	-0.124	-0.4017	Yes
224	NAB2	NAB2	20634	-0.124	-0.3998	Yes
225	IGFBP3	IGFBP3	20754	-0.131	-0.4020	Yes
226	DACT1	DACT1	20763	-0.132	-0.3996	Yes
227	FZD5	FZD5	20828	-0.135	-0.3995	Yes
228	SDC4	SDC4	20885	-0.139	-0.3989	Yes
229	CTSS	CTSS	20979	-0.149	-0.3997	Yes
230	LRRN3	LRRN3	21008	-0.153	-0.3977	Yes
231	CAMK2D	CAMK2D	21027	-0.154	-0.3952	Yes
232	IL1RAP	IL1RAP	21028	-0.154	-0.3920	Yes
233	DTX3L	DTX3L	21046	-0.156	-0.3895	Yes
234	PARP9	PARP9	21047	-0.156	-0.3862	Yes
235	CAPN5	CAPN5	21078	-0.159	-0.3842	Yes
236	STOM	STOM	21124	-0.163	-0.3827	Yes
237	EMP1	EMP1	21196	-0.170	-0.3821	Yes
238	GABRA5	GABRA5	21210	-0.172	-0.3791	Yes
239	L1CAM	L1CAM	21234	-0.174	-0.3764	Yes
240	SPSB1	SPSB1	21522	-0.205	-0.3841	Yes
241	LRP2	LRP2	21548	-0.208	-0.3808	Yes
242	FGF2	FGF2	21561	-0.209	-0.3769	Yes
243	SH2B3	SH2B3	21658	-0.219	-0.3764	Yes
244	CITED4	CITED4	21737	-0.230	-0.3748	Yes
245	IFIH1	IFIH1	21835	-0.244	-0.3738	Yes
246	BMP5	BMP5	21844	-0.245	-0.3690	Yes
247	EMILIN2	EMILIN2	21848	-0.246	-0.3641	Yes
248	CYP1A1	CYP1A1	21869	-0.249	-0.3597	Yes
249	A2M	A2M	21880	-0.251	-0.3549	Yes
250	CDC42EP5	CDC42EP5	21895	-0.253	-0.3503	Yes
251	GFRA1	GFRA1	21969	-0.266	-0.3478	Yes
252	BACE2	BACE2	22035	-0.275	-0.3448	Yes
253	SLC2A3	SLC2A3	22057	-0.278	-0.3399	Yes
254	TNFRSF12A	TNFRSF12A	22148	-0.293	-0.3375	Yes
255	VGF	VGF	22175	-0.298	-0.3324	Yes
256	NR4A3	NR4A3	22302	-0.321	-0.3310	Yes
257	SYNPO	SYNPO	22326	-0.327	-0.3251	Yes
258	TRPM8	TRPM8	22449	-0.349	-0.3230	Yes
259	MICALL2	MICALL2	23001	-0.362	-0.3383	Yes
260	LARP6	LARP6	23042	-0.371	-0.3323	Yes
261	ADAMTS14	ADAMTS14	23098	-0.380	-0.3267	Yes
262	CDKN2B	CDKN2B	23135	-0.392	-0.3200	Yes
263	SPP1	SPP1	23241	-0.405	-0.3160	Yes
264	ASPHD1	ASPHD1	23321	-0.424	-0.3105	Yes
265	CSRP2	CSRP2	23365	-0.436	-0.3032	Yes
266	EGFLAM	EGFLAM	23396	-0.445	-0.2952	Yes
267	RGS16	RGS16	23418	-0.454	-0.2867	Yes
268	IL4I1	IL4I1	23432	-0.459	-0.2777	Yes
269	PERP	PERP	23434	-0.459	-0.2682	Yes
270	ASB9	ASB9	23592	-0.524	-0.2638	Yes
271	DOC2B	DOC2B	23605	-0.530	-0.2533	Yes
272	PGM2L1	PGM2L1	23652	-0.545	-0.2439	Yes
273	TNFRSF9	TNFRSF9	23679	-0.558	-0.2335	Yes
274	PTPRE	PTPRE	23712	-0.582	-0.2227	Yes
275	PHF24	PHF24	23716	-0.585	-0.2107	Yes
276	ARHGEF16	ARHGEF16	23807	-0.638	-0.2012	Yes
277	FADS3	FADS3	23982	-0.718	-0.1935	Yes
278	AHR	AHR	24012	-0.750	-0.1792	Yes
279	ISG20	ISG20	24023	-0.758	-0.1639	Yes
280	MAOB	MAOB	24025	-0.758	-0.1482	Yes
281	CD83	CD83	24121	-0.915	-0.1331	Yes
282	FAM129A	FAM129A	24138	-0.933	-0.1144	Yes
283	ETNK2	ETNK2	24158	-0.983	-0.0948	Yes
284	SGPP2	SGPP2	24322	-1.513	-0.0702	Yes
285	NRG1	NRG1	24335	-1.630	-0.0369	Yes
286	LHX9	LHX9	24365	-1.883	0.0010	Yes