Details for gene set SCHMITT_HMG

Table: GSEA Results Summary

Dataset	NSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls #Fosl1_versus_Ctrl_repos
Phenotype	NSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	SCHMITT_HMG_2020
Enrichment Score (ES)	-0.35737228
Normalized Enrichment Score (NES)	-1.151571
Nominal p-value	0.18888889
FDR q-value	0.37685576
FWER p-Value	0.934

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PMP2	PMP2	154	0.771	0.0142	No
2	PTGES	PTGES	341	0.587	0.0221	No
3	GRIK1	GRIK1	494	0.526	0.0298	No
4	ICAM1	ICAM1	511	0.517	0.0429	No
5	LBHD1	LBHD1	563	0.487	0.0538	No
6	JAK3	JAK3	589	0.477	0.0655	No
7	IL13RA1	IL13RA1	649	0.452	0.0751	No
8	GDA	GDA	852	0.418	0.0778	No
9	GPX3	GPX3	1040	0.403	0.0808	No
10	PDK4	PDK4	1050	0.401	0.0912	No
11	SLC16A4	SLC16A4	1066	0.397	0.1011	No
12	C1QL1	C1QL1	1134	0.374	0.1083	No
13	CCNB1IP1	CCNB1IP1	1150	0.369	0.1175	No
14	OSMR	OSMR	1318	0.324	0.1192	No
15	MYO5B	MYO5B	1349	0.316	0.1264	No
16	CCDC113	CCDC113	1419	0.301	0.1315	No
17	SOCS3	SOCS3	1528	0.284	0.1346	No
18	BCAM	BCAM	1533	0.282	0.1420	No
19	EFNA1	EFNA1	1653	0.263	0.1441	No
20	NDRG2	NDRG2	2656	0.228	0.1086	No
21	LAPTM5	LAPTM5	2742	0.215	0.1108	No
22	WIPI1	WIPI1	2844	0.202	0.1120	No
23	APOL6	APOL6	2872	0.198	0.1162	No
24	KCNK10	KCNK10	2884	0.197	0.1210	No
25	CLU	CLU	3055	0.180	0.1187	No
26	ALPK1	ALPK1	3199	0.167	0.1172	No
27	VASH2	VASH2	3413	0.148	0.1123	No
28	PTP4A3	PTP4A3	3444	0.145	0.1150	No
29	ZFP36	ZFP36	3467	0.143	0.1179	No
30	MEIS3	MEIS3	3494	0.141	0.1205	No
31	TIMP1	TIMP1	3528	0.139	0.1229	No
32	LIN7A	LIN7A	3548	0.137	0.1257	No
33	UBALD2	UBALD2	3635	0.131	0.1257	No
34	CBX7	CBX7	3708	0.128	0.1261	No
35	PROS1	PROS1	3891	0.116	0.1216	No
36	DUSP5	DUSP5	3914	0.115	0.1238	No
37	HOTAIRM1	HOTAIRM1	3989	0.112	0.1237	No
38	SPTB	SPTB	3992	0.112	0.1266	No
39	CISH	CISH	4095	0.107	0.1252	No
40	LIFR	LIFR	4103	0.106	0.1277	No
41	EEPD1	EEPD1	4134	0.105	0.1293	No
42	HSD3B7	HSD3B7	4159	0.104	0.1311	No
43	YPEL3	YPEL3	4172	0.104	0.1334	No
44	ZBTB46	ZBTB46	4217	0.102	0.1342	No
45	CIB1	CIB1	4338	0.096	0.1318	No
46	GLRX	GLRX	4365	0.095	0.1333	No
47	ZFP28	ZFP28	4510	0.088	0.1297	No
48	C4A	C4A	4520	0.088	0.1316	No
49	SLC2A4	SLC2A4	4643	0.083	0.1288	No
50	ENO3	ENO3	4765	0.079	0.1259	No
51	TCP11L2	TCP11L2	4804	0.078	0.1264	No
52	PORCN	PORCN	4850	0.076	0.1265	No
53	SRPX	SRPX	4855	0.076	0.1284	No
54	IFITM2	IFITM2	4895	0.075	0.1288	No
55	NRCAM	NRCAM	4924	0.075	0.1296	No
56	GADD45A	GADD45A	4991	0.073	0.1288	No
57	CITED1	CITED1	5116	0.069	0.1255	No
58	USP51	USP51	5197	0.067	0.1240	No
59	F3	F3	5284	0.065	0.1222	No
60	ARID5A	ARID5A	5354	0.063	0.1210	No
61	MCEE	MCEE	5364	0.063	0.1223	No
62	YPEL2	YPEL2	5405	0.062	0.1223	No
63	MVP	MVP	5446	0.061	0.1223	No
64	SH3BP5	SH3BP5	5525	0.060	0.1206	No
65	PPM1K	PPM1K	5666	0.057	0.1163	No
66	YIPF2	YIPF2	5668	0.057	0.1178	No
67	APOE	APOE	5860	0.053	0.1113	No
68	ARRDC3	ARRDC3	5864	0.053	0.1126	No
69	RPL37A	RPL37A	5895	0.052	0.1127	No
70	PIK3IP1	PIK3IP1	5928	0.052	0.1128	No
71	ABHD4	ABHD4	6011	0.050	0.1107	No
72	PLSCR4	PLSCR4	6078	0.049	0.1093	No
73	BCL6	BCL6	6184	0.048	0.1062	No
74	AGT	AGT	6195	0.047	0.1070	No
75	ADGRD1	ADGRD1	6220	0.047	0.1073	No
76	PITPNC1	PITPNC1	6436	0.043	0.0995	No
77	CIR1	CIR1	6577	0.041	0.0948	No
78	TAF1D	TAF1D	6596	0.041	0.0952	No
79	LGMN	LGMN	6653	0.040	0.0939	No
80	CRELD1	CRELD1	6679	0.040	0.0940	No
81	FGFBP3	FGFBP3	6702	0.040	0.0941	No
82	EIF2AK3	EIF2AK3	6703	0.040	0.0952	No
83	TNFRSF1A	TNFRSF1A	6759	0.039	0.0939	No
84	ARF4	ARF4	6765	0.039	0.0947	No
85	ACSL6	ACSL6	6868	0.037	0.0915	No
86	SNHG20	SNHG20	6908	0.037	0.0909	No
87	PIM1	PIM1	6989	0.036	0.0885	No
88	RAB4A	RAB4A	6990	0.036	0.0894	No
89	SC5D	SC5D	7200	0.033	0.0817	No
90	TMEM231	TMEM231	7568	0.029	0.0672	No
91	PLA2G4C	PLA2G4C	7624	0.028	0.0657	No
92	TPST1	TPST1	7662	0.027	0.0649	No
93	CYB561D2	CYB561D2	7756	0.027	0.0617	No
94	YOD1	YOD1	7758	0.027	0.0624	No
95	ATP1B2	ATP1B2	7802	0.026	0.0613	No
96	POLR3D	POLR3D	7906	0.025	0.0577	No
97	CSF1	CSF1	7934	0.025	0.0572	No
98	TMEM97	TMEM97	8038	0.023	0.0536	No
99	MOSPD1	MOSPD1	8040	0.023	0.0542	No
100	DRAM2	DRAM2	8249	0.021	0.0461	No
101	SLC50A1	SLC50A1	8282	0.021	0.0453	No
102	CBS	CBS	8300	0.021	0.0452	No
103	PFKFB2	PFKFB2	8502	0.019	0.0373	No
104	SYN3	SYN3	8573	0.018	0.0349	No
105	THBS2	THBS2	8609	0.018	0.0339	No
106	PTCHD1	PTCHD1	8641	0.017	0.0331	No
107	RGS3	RGS3	8720	0.017	0.0303	No
108	TMEM50B	TMEM50B	8811	0.016	0.0270	No
109	S100A10	S100A10	8879	0.015	0.0247	No
110	CLIP2	CLIP2	9027	0.014	0.0189	No
111	VMAC	VMAC	9344	0.011	0.0061	No
112	TAGLN2	TAGLN2	9367	0.011	0.0055	No
113	AKNA	AKNA	9394	0.011	0.0047	No
114	STK19	STK19	9439	0.010	0.0032	No
115	MAP3K6	MAP3K6	9469	0.010	0.0022	No
116	CRTAP	CRTAP	9709	0.008	-0.0075	No
117	ATCAY	ATCAY	9761	0.007	-0.0094	No
118	DDR1	DDR1	9793	0.007	-0.0105	No
119	PIKFYVE	PIKFYVE	9869	0.007	-0.0134	No
120	TBC1D23	TBC1D23	10019	0.005	-0.0195	No
121	CDHR1	CDHR1	10099	0.005	-0.0226	No
122	GOLT1B	GOLT1B	10182	0.004	-0.0259	No
123	PMP22	PMP22	10332	0.003	-0.0320	No
124	MYCN	MYCN	10393	0.002	-0.0344	No
125	N4BP2L1	N4BP2L1	10582	0.000	-0.0422	No
126	HMGCS1	HMGCS1	12988	0.000	-0.1420	No
127	IL21R	IL21R	13037	0.000	-0.1440	No
128	BLOC1S3	BLOC1S3	15023	-0.002	-0.2262	No
129	UFM1	UFM1	15136	-0.003	-0.2308	No
130	COG6	COG6	15223	-0.004	-0.2343	No
131	IDI1	IDI1	15332	-0.004	-0.2386	No
132	ACBD3	ACBD3	15419	-0.005	-0.2421	No
133	TSC22D3	TSC22D3	15639	-0.007	-0.2510	No
134	ZFPL1	ZFPL1	15712	-0.008	-0.2537	No
135	ACSS2	ACSS2	15721	-0.008	-0.2538	No
136	SERPINE1	SERPINE1	15830	-0.009	-0.2581	No
137	RAB3B	RAB3B	15894	-0.009	-0.2605	No
138	INSIG1	INSIG1	16227	-0.013	-0.2739	No
139	GOLGA2	GOLGA2	16275	-0.013	-0.2755	No
140	ERLEC1	ERLEC1	16278	-0.013	-0.2752	No
141	GPR107	GPR107	16368	-0.014	-0.2785	No
142	KDELR3	KDELR3	16508	-0.016	-0.2839	No
143	SLC30A5	SLC30A5	16516	-0.016	-0.2837	No
144	TMCC3	TMCC3	16520	-0.016	-0.2834	No
145	TMEM87B	TMEM87B	16580	-0.016	-0.2854	No
146	SEMA4B	SEMA4B	16590	-0.016	-0.2854	No
147	GOSR2	GOSR2	16610	-0.017	-0.2857	No
148	GOLGA4	GOLGA4	16756	-0.018	-0.2913	No
149	EPHA5	EPHA5	16857	-0.019	-0.2949	No
150	GOLGB1	GOLGB1	16858	-0.019	-0.2944	No
151	LMAN1	LMAN1	16911	-0.020	-0.2960	No
152	RAB5A	RAB5A	16927	-0.020	-0.2961	No
153	RDH10	RDH10	16938	-0.020	-0.2959	No
154	ZBTB41	ZBTB41	16939	-0.020	-0.2954	No
155	TRIM7	TRIM7	16941	-0.020	-0.2949	No
156	PDP2	PDP2	17049	-0.022	-0.2988	No
157	MSMO1	MSMO1	17081	-0.022	-0.2995	No
158	LDLR	LDLR	17170	-0.023	-0.3025	No
159	FBXO32	FBXO32	17191	-0.023	-0.3027	No
160	MATN2	MATN2	17308	-0.025	-0.3068	No
161	TBC1D15	TBC1D15	17342	-0.025	-0.3075	No
162	PDXDC1	PDXDC1	17348	-0.025	-0.3071	No
163	AOC2	AOC2	17383	-0.026	-0.3078	No
164	VMP1	VMP1	17464	-0.027	-0.3104	No
165	ITGA10	ITGA10	17488	-0.027	-0.3106	No
166	MTUS1	MTUS1	17590	-0.028	-0.3141	No
167	SGK1	SGK1	17712	-0.030	-0.3183	No
168	COL11A2	COL11A2	17740	-0.031	-0.3186	No
169	NPC2	NPC2	17773	-0.031	-0.3191	No
170	HABP4	HABP4	17879	-0.033	-0.3226	No
171	HMGXB3	HMGXB3	17902	-0.033	-0.3226	No
172	TMEM173	TMEM173	17927	-0.033	-0.3227	No
173	SYDE2	SYDE2	18061	-0.036	-0.3273	No
174	GOLGA5	GOLGA5	18102	-0.036	-0.3280	No
175	MALT1	MALT1	18169	-0.037	-0.3297	No
176	PPP2R5A	PPP2R5A	18222	-0.038	-0.3309	No
177	GCNT4	GCNT4	18243	-0.039	-0.3307	No
178	PMM2	PMM2	18276	-0.039	-0.3309	No
179	PJA2	PJA2	18298	-0.040	-0.3307	No
180	MAFF	MAFF	18299	-0.040	-0.3297	No
181	EDEM3	EDEM3	18308	-0.040	-0.3290	No
182	LONRF1	LONRF1	18320	-0.040	-0.3283	No
183	SNX10	SNX10	18335	-0.040	-0.3278	No
184	FAM114A1	FAM114A1	18380	-0.041	-0.3286	No
185	TRAF1	TRAF1	18411	-0.042	-0.3287	No
186	IFITM1	IFITM1	18435	-0.042	-0.3285	No
187	PDE4DIP	PDE4DIP	18497	-0.043	-0.3299	No
188	SEC14L1	SEC14L1	18540	-0.044	-0.3305	No
189	ACAN	ACAN	18550	-0.045	-0.3296	No
190	GOLGA3	GOLGA3	18596	-0.046	-0.3303	No
191	TMEM120A	TMEM120A	18652	-0.047	-0.3313	No
192	FMN2	FMN2	18725	-0.048	-0.3330	No
193	COL6A1	COL6A1	18805	-0.050	-0.3350	No
194	MAN2A1	MAN2A1	18907	-0.053	-0.3377	No
195	CHN2	CHN2	18912	-0.053	-0.3365	No
196	JAG2	JAG2	19112	-0.059	-0.3432	No
197	NUAK2	NUAK2	19150	-0.060	-0.3431	No
198	RUNX1T1	RUNX1T1	19202	-0.062	-0.3436	No
199	CCNG1	CCNG1	19260	-0.063	-0.3443	No
200	DNAJB5	DNAJB5	19300	-0.065	-0.3442	No
201	CDKL3	CDKL3	19378	-0.067	-0.3456	No
202	KCNA4	KCNA4	19512	-0.072	-0.3492	No
203	TXNIP	TXNIP	19557	-0.074	-0.3490	No
204	GJA3	GJA3	19579	-0.074	-0.3479	No
205	NAMPT	NAMPT	19644	-0.077	-0.3485	No
206	DBP	DBP	19676	-0.079	-0.3477	No
207	MKNK1	MKNK1	19689	-0.079	-0.3461	No
208	CDKN1A	CDKN1A	19702	-0.080	-0.3445	No
209	KLF9	KLF9	19731	-0.081	-0.3435	No
210	KLF6	KLF6	19927	-0.090	-0.3492	No
211	ARMCX1	ARMCX1	19940	-0.091	-0.3472	No
212	SPTY2D1	SPTY2D1	19946	-0.091	-0.3450	No
213	CD44	CD44	19954	-0.091	-0.3429	No
214	TNC	TNC	19967	-0.092	-0.3409	No
215	SLC26A2	SLC26A2	20050	-0.096	-0.3418	No
216	PODXL	PODXL	20071	-0.097	-0.3400	No
217	PDP1	PDP1	20145	-0.101	-0.3404	No
218	CLDN4	CLDN4	20291	-0.107	-0.3435	No
219	HDAC9	HDAC9	20388	-0.111	-0.3445	No
220	DGKI	DGKI	20677	-0.127	-0.3531	No
221	EPHX1	EPHX1	20781	-0.132	-0.3538	Yes
222	FZD5	FZD5	20828	-0.135	-0.3521	Yes
223	RPE65	RPE65	20877	-0.138	-0.3504	Yes
224	JADE2	JADE2	20889	-0.140	-0.3472	Yes
225	GLIS3	GLIS3	20957	-0.147	-0.3460	Yes
226	IRF9	IRF9	20986	-0.150	-0.3432	Yes
227	CAMK2D	CAMK2D	21027	-0.154	-0.3407	Yes
228	DTX3L	DTX3L	21046	-0.156	-0.3373	Yes
229	SPARC	SPARC	21114	-0.162	-0.3358	Yes
230	ABCD2	ABCD2	21118	-0.163	-0.3316	Yes
231	GPR20	GPR20	21135	-0.164	-0.3278	Yes
232	PKIG	PKIG	21151	-0.165	-0.3241	Yes
233	NEDD9	NEDD9	21158	-0.166	-0.3199	Yes
234	EMP1	EMP1	21196	-0.170	-0.3169	Yes
235	FUT1	FUT1	21286	-0.180	-0.3158	Yes
236	NUPR1	NUPR1	21314	-0.184	-0.3120	Yes
237	GBP2	GBP2	21326	-0.185	-0.3075	Yes
238	ATF3	ATF3	21368	-0.190	-0.3041	Yes
239	ANXA11	ANXA11	21579	-0.211	-0.3072	Yes
240	SLC22A18	SLC22A18	21596	-0.212	-0.3022	Yes
241	BST2	BST2	21635	-0.216	-0.2981	Yes
242	RCN3	RCN3	21673	-0.220	-0.2937	Yes
243	BMP5	BMP5	21844	-0.245	-0.2942	Yes
244	PRICKLE2	PRICKLE2	21857	-0.248	-0.2881	Yes
245	A2M	A2M	21880	-0.251	-0.2823	Yes
246	EML2	EML2	21882	-0.251	-0.2757	Yes
247	CRYAB	CRYAB	21884	-0.252	-0.2690	Yes
248	TRIQK	TRIQK	21944	-0.260	-0.2645	Yes
249	SYNM	SYNM	21947	-0.261	-0.2577	Yes
250	LYST	LYST	22043	-0.276	-0.2542	Yes
251	SLC2A3	SLC2A3	22057	-0.278	-0.2474	Yes
252	LIPG	LIPG	22107	-0.286	-0.2418	Yes
253	COL6A2	COL6A2	22117	-0.287	-0.2345	Yes
254	VGF	VGF	22175	-0.298	-0.2289	Yes
255	TLCD2	TLCD2	22251	-0.311	-0.2237	Yes
256	TTC39B	TTC39B	22254	-0.312	-0.2155	Yes
257	FGD4	FGD4	22299	-0.321	-0.2088	Yes
258	NR4A3	NR4A3	22302	-0.321	-0.2003	Yes
259	SYCP2	SYCP2	22322	-0.326	-0.1924	Yes
260	ATG9B	ATG9B	22362	-0.333	-0.1851	Yes
261	MERTK	MERTK	22373	-0.334	-0.1766	Yes
262	FABP3	FABP3	22389	-0.337	-0.1682	Yes
263	COL14A1	COL14A1	22421	-0.344	-0.1603	Yes
264	TRPM8	TRPM8	22449	-0.349	-0.1522	Yes
265	FSTL5	FSTL5	23043	-0.372	-0.1668	Yes
266	GREM2	GREM2	23392	-0.443	-0.1695	Yes
267	RGS16	RGS16	23418	-0.454	-0.1584	Yes
268	AHNAK	AHNAK	23609	-0.531	-0.1521	Yes
269	PGM2L1	PGM2L1	23652	-0.545	-0.1393	Yes
270	PHF24	PHF24	23716	-0.585	-0.1264	Yes
271	ISG20	ISG20	24023	-0.758	-0.1188	Yes
272	PDGFRB	PDGFRB	24091	-0.852	-0.0989	Yes
273	THEMIS2	THEMIS2	24103	-0.877	-0.0760	Yes
274	ITGA11	ITGA11	24303	-1.408	-0.0467	Yes
275	LHX9	LHX9	24365	-1.883	0.0010	Yes