DatasetNSCs_shNf1_sgFosl1.NSCs_shNf1_sgFosl1.cls
#Fosl1_versus_Ctrl.NSCs_shNf1_sgFosl1.cls
#Fosl1_versus_Ctrl_repos
PhenotypeNSCs_shNf1_sgFosl1.cls#Fosl1_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetFOSL1_REGULON
Enrichment Score (ES)-0.5214364
Normalized Enrichment Score (NES)-1.5120555
Nominal p-value0.034042552
FDR q-value0.10422026
FWER p-Value0.176
Table: GSEA Results Summary



Fig 1: Enrichment plot: FOSL1_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MOCOSMOCOS1150.8100.0172No
2VDRVDR4840.5330.0164No
3KCNN4KCNN44870.5280.0306No
4IL13RA1IL13RA16490.4520.0362No
5LIFLIF6680.4450.0475No
6DRAM1DRAM17180.4340.0572No
7SRPX2SRPX27240.4340.0687No
8CYBRD1CYBRD112160.3510.0579No
9SH2D4ASH2D4A14300.3000.0572No
10MAST1MAST116150.2690.0569No
11PTHLHPTHLH16490.2630.0627No
12WIPI1WIPI128440.2020.0187No
13PLAUPLAU28660.1990.0232No
14KCND2KCND230360.1810.0212No
15GFPT2GFPT231090.1750.0229No
16BFSP1BFSP132210.1650.0228No
17CXXC4CXXC432580.1620.0257No
18RELBRELB32680.1610.0297No
19TIMP1TIMP135280.1390.0227No
20CBX7CBX737080.1280.0188No
21TNFRSF10BTNFRSF10B37480.1240.0205No
22TFPI2TFPI238150.1200.0210No
23ADORA2BADORA2B38990.1160.0207No
24DLX2DLX239910.1120.0200No
25CDC42EP3CDC42EP340320.1100.0213No
26PLEKHF1PLEKHF142180.1020.0164No
27CD46CD4642240.1020.0190No
28FUT9FUT943250.0970.0174No
29GLRXGLRX43650.0950.0184No
30ETHE1ETHE144440.0910.0176No
31SMAGPSMAGP44610.0900.0194No
32TSPAN7TSPAN746240.0830.0150No
33STC1STC147770.0790.0108No
34RHOGRHOG50420.0710.0018No
35CHD7CHD750750.0700.0024No
36MVPMVP54460.061-0.0112No
37MYD88MYD8855850.058-0.0154No
38ARSAARSA55940.058-0.0141No
39CTNND2CTNND257010.056-0.0170No
40RNFT2RNFT260450.050-0.0298No
41CEBPBCEBPB61850.048-0.0343No
42MAP2MAP264120.044-0.0425No
43REXO2REXO265320.042-0.0462No
44ATOX1ATOX166440.040-0.0497No
45TSPAN1TSPAN167050.040-0.0512No
46FADDFADD67420.039-0.0516No
47MYLKMYLK68120.038-0.0534No
48ITGA5ITGA569400.036-0.0577No
49CLIP4CLIP471080.034-0.0637No
50EDEM1EDEM171550.034-0.0646No
51BET1LBET1L71850.033-0.0649No
52MARCKSL1MARCKSL172310.033-0.0659No
53TMED9TMED975260.029-0.0773No
54ANP32AANP32A75270.029-0.0765No
55KCNAB2KCNAB276460.028-0.0806No
56TPD52L2TPD52L279660.024-0.0932No
57TCF4TCF481690.022-0.1009No
58ARFRP1ARFRP183850.020-0.1093No
59IFRD2IFRD286500.017-0.1197No
60SSH3SSH388480.016-0.1274No
61S100A10S100A1088790.015-0.1283No
62GEMGEM89220.015-0.1296No
63FOXC1FOXC189400.015-0.1299No
64VASPVASP90490.014-0.1340No
65YIF1AYIF1A91510.013-0.1378No
66CDKN1BCDKN1B92510.012-0.1416No
67ABCD1ABCD199930.005-0.1721No
68SLC38A10SLC38A10100610.005-0.1747No
69PIGTPIGT101060.005-0.1764No
70SLC4A7SLC4A7101720.004-0.1790No
71ANXA1ANXA1102760.003-0.1832No
72WDR55WDR55103480.002-0.1861No
73SLC35C1SLC35C114908-0.001-0.3746No
74PRNPPRNP15108-0.003-0.3827No
75TMEM214TMEM21415119-0.003-0.3831No
76GSDMDGSDMD15450-0.005-0.3966No
77ARPC1BARPC1B15616-0.007-0.4032No
78ITGA6ITGA615693-0.008-0.4062No
79FYCO1FYCO115713-0.008-0.4067No
80SERPINE1SERPINE115830-0.009-0.4113No
81DCBLD2DCBLD215941-0.010-0.4156No
82MGAT4BMGAT4B16035-0.011-0.4191No
83FBRSFBRS16041-0.011-0.4190No
84RHBDF2RHBDF216132-0.012-0.4224No
85ADRM1ADRM116232-0.013-0.4262No
86S100A13S100A1316435-0.015-0.4341No
87DNAJC10DNAJC1016505-0.016-0.4366No
88KDELR3KDELR316508-0.016-0.4362No
89DRAP1DRAP116540-0.016-0.4371No
90RRBP1RRBP116591-0.016-0.4387No
91COQ10BCOQ10B16755-0.018-0.4449No
92EMP3EMP316762-0.018-0.4447No
93TMEM109TMEM10916979-0.021-0.4531No
94QSOX1QSOX116995-0.021-0.4531No
95DSTNDSTN17009-0.021-0.4531No
96FLIIFLII17011-0.021-0.4525No
97ZMYM4ZMYM417046-0.022-0.4534No
98EXOC3EXOC317088-0.022-0.4545No
99DEGS1DEGS117089-0.022-0.4539No
100B3GNT2B3GNT217124-0.023-0.4547No
101YIPF3YIPF317160-0.023-0.4555No
102MAFGMAFG17175-0.023-0.4554No
103LRRFIP2LRRFIP217343-0.025-0.4617No
104ADSSADSS17435-0.026-0.4647No
105PNPLA2PNPLA217451-0.026-0.4646No
106HSPA5HSPA517529-0.027-0.4671No
107PYGBPYGB17535-0.028-0.4665No
108CSRP1CSRP117567-0.028-0.4670No
109MGAT1MGAT117682-0.030-0.4710No
110NSMAFNSMAF17710-0.030-0.4713No
111LGALS8LGALS817818-0.032-0.4748No
112CUL7CUL717865-0.032-0.4758No
113MCFD2MCFD217913-0.033-0.4769No
114PARVBPARVB18018-0.035-0.4803No
115CLIC1CLIC118140-0.037-0.4843No
116GBE1GBE118170-0.037-0.4845No
117GLIPR1GLIPR118201-0.038-0.4847No
118SH3BGRL3SH3BGRL318251-0.039-0.4856No
119ECM1ECM118376-0.041-0.4897No
120IQGAP1IQGAP118498-0.043-0.4935No
121CAPN2CAPN218601-0.046-0.4965No
122FLNAFLNA18719-0.048-0.5000No
123LGALS1LGALS118926-0.053-0.5071No
124FOXN3FOXN319085-0.058-0.5120No
125PMAIP1PMAIP119107-0.058-0.5113No
126FOSL2FOSL219180-0.061-0.5127No
127PLCB1PLCB119196-0.061-0.5116No
128ACTN4ACTN419250-0.063-0.5121No
129TRAM2TRAM219266-0.064-0.5110No
130SERINC3SERINC319317-0.065-0.5113No
131PARVAPARVA19372-0.067-0.5117No
132CAV2CAV219408-0.069-0.5113No
133VCLVCL19438-0.070-0.5106No
134PXNPXN19583-0.075-0.5145No
135IMPAD1IMPAD119595-0.075-0.5130No
136KLHL21KLHL2119631-0.077-0.5123No
137FURINFURIN19684-0.079-0.5124No
138TAPBPTAPBP19699-0.079-0.5108No
139ATP1A1ATP1A119740-0.081-0.5102No
140WDR1WDR119790-0.084-0.5100No
141PLP2PLP219799-0.084-0.5081No
142LPPLPP19943-0.091-0.5115No
143CD44CD4419954-0.091-0.5095No
144ZBTB38ZBTB3819975-0.092-0.5078No
145SQSTM1SQSTM120077-0.098-0.5093No
146IER3IER320182-0.102-0.5109No
147ANXA4ANXA420186-0.103-0.5082No
148RBKSRBKS20507-0.117-0.5183Yes
149SYNJ2SYNJ220519-0.118-0.5155Yes
150ESYT1ESYT120568-0.120-0.5143Yes
151MYH9MYH920636-0.124-0.5137Yes
152RPS6KA4RPS6KA420745-0.130-0.5146Yes
153BAG3BAG320851-0.138-0.5152Yes
154SDC4SDC420885-0.139-0.5128Yes
155RNH1RNH120892-0.140-0.5093Yes
156MYO1CMYO1C20897-0.140-0.5056Yes
157GSTA4GSTA420940-0.145-0.5035Yes
158KCND1KCND120941-0.145-0.4995Yes
159CRIM1CRIM120947-0.146-0.4958Yes
160UPP1UPP121058-0.157-0.4961Yes
161EMP1EMP121196-0.170-0.4971Yes
162FAHFAH21237-0.174-0.4941Yes
163CASTCAST21363-0.190-0.4941Yes
164PARP12PARP1221383-0.192-0.4897Yes
165CRTAMCRTAM21490-0.203-0.4886Yes
166LMNALMNA21572-0.210-0.4863Yes
167ANXA11ANXA1121579-0.211-0.4808Yes
168SH2B3SH2B321658-0.219-0.4781Yes
169SHC1SHC121741-0.230-0.4753Yes
170SLC10A3SLC10A321813-0.241-0.4717Yes
171RAVER2RAVER221909-0.255-0.4687Yes
172ACTN1ACTN121926-0.257-0.4624Yes
173BACE2BACE222035-0.275-0.4595Yes
174P4HA2P4HA222070-0.281-0.4533Yes
175NT5ENT5E22108-0.287-0.4470Yes
176COL6A2COL6A222117-0.287-0.4396Yes
177RIN1RIN122120-0.288-0.4319Yes
178ANPEPANPEP22140-0.292-0.4248Yes
179TNFRSF12ATNFRSF12A22148-0.293-0.4172Yes
180PRSS23PRSS2322159-0.295-0.4096Yes
181RAC2RAC222161-0.295-0.4017Yes
182PROCRPROCR22311-0.323-0.3991Yes
183PTGER4PTGER422332-0.329-0.3910Yes
184COL18A1COL18A122357-0.332-0.3830Yes
185ANXA2ANXA222374-0.334-0.3746Yes
186IL11IL1123152-0.395-0.3961Yes
187PLAURPLAUR23251-0.408-0.3891Yes
188AXLAXL23290-0.416-0.3794Yes
189PHLDA2PHLDA223371-0.437-0.3709Yes
190PERPPERP23434-0.459-0.3610Yes
191OLFML2BOLFML2B23440-0.462-0.3487Yes
192ITGA3ITGA323486-0.477-0.3377Yes
193S100A11S100A1123510-0.487-0.3255Yes
194PQLC3PQLC323524-0.491-0.3127Yes
195AHNAKAHNAK23609-0.531-0.3018Yes
196MICAL2MICAL223614-0.532-0.2876Yes
197MYOFMYOF23756-0.619-0.2767Yes
198CYB561CYB56123857-0.641-0.2634Yes
199IL18R1IL18R123880-0.650-0.2468Yes
200FADS3FADS323982-0.718-0.2315Yes
201METMET24021-0.756-0.2126Yes
202TPM2TPM224050-0.788-0.1925Yes
203CAV1CAV124167-1.007-0.1700Yes
204FHL2FHL224205-1.090-0.1421Yes
205SEMA4FSEMA4F24247-1.192-0.1115Yes
206EPHA2EPHA224249-1.201-0.0791Yes
207S100A6S100A624307-1.423-0.0429Yes
208GLT8D2GLT8D224346-1.7080.0017Yes
Table: GSEA details [plain text format]



Fig 2: FOSL1_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FOSL1_REGULON: Random ES distribution   
Gene set null distribution of ES for FOSL1_REGULON