DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshCtrl
GeneSetVERHAAK_PN_2010
Enrichment Score (ES)-0.31741506
Normalized Enrichment Score (NES)-1.4421126
Nominal p-value0.005076142
FDR q-value0.03953936
FWER p-Value0.315
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_PN_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ALCAMALCAM450.1000.0191No
2CBX1CBX1580.0980.0392No
3RAP2ARAP2A2360.0750.0468No
4ZNF286AZNF286A2950.0700.0589No
5GPM6AGPM6A4220.0650.0667No
6CNTN1CNTN14520.0630.0787No
7DNM3DNM35480.0600.0869No
8ACTR1AACTR1A7470.0550.0894No
9TOP2BTOP2B7940.0550.0987No
10CAMSAP1L1CAMSAP1L18290.0540.1085No
11DBN1DBN18400.0540.1194No
12RAD21RAD218630.0530.1296No
13GABRA3GABRA39890.0510.1344No
14FHOD3FHOD315160.0430.1190No
15ZNF510ZNF51017940.0410.1146No
16BCORBCOR18300.0400.1215No
17SEZ6LSEZ6L20220.0380.1207No
18TTC3TTC321760.0370.1213No
19HDAC2HDAC225300.0340.1121No
20NOL4NOL430410.0310.0948No
21LPHN3LPHN330720.0310.0998No
22E2F3E2F331080.0300.1046No
23HOXD3HOXD334320.0280.0955No
24NRXN2NRXN234920.0280.0986No
25SOX11SOX1135150.0280.1034No
26FGF9FGF935780.0270.1063No
27SLC1A1SLC1A136120.0270.1105No
28PAK3PAK336670.0270.1136No
29MLLT11MLLT1140750.0250.0998No
30BCL7ABCL7A41260.0240.1026No
31SLCO5A1SLCO5A142990.0240.0995No
32ZNF184ZNF18444980.0230.0951No
33MPPED2MPPED245500.0220.0974No
34ZEB2ZEB246140.0220.0991No
35TNRC4TNRC450830.0200.0814No
36DPP6DPP651040.0200.0847No
37CLASP2CLASP251190.0200.0882No
38PAK7PAK752150.0190.0878No
39PCDH11YPCDH11Y52650.0190.0896No
40MMP16MMP1653480.0190.0897No
41VEZF1VEZF153970.0180.0913No
42DCXDCX58060.0170.0758No
43NCAM1NCAM164260.0140.0499No
44LRRTM4LRRTM464290.0140.0528No
45ATAD5ATAD564350.0140.0555No
46TOPBP1TOPBP165310.0140.0540No
47GRID2GRID268740.0120.0406No
48SPTBN2SPTBN270010.0120.0373No
49CXXC4CXXC473550.0110.0230No
50KLRC4KLRC475260.0100.0173No
51FBXO21FBXO2177280.0100.0099No
52SRGAP3SRGAP377460.0090.0111No
53GSK3BGSK3B78020.0090.0105No
54MATR3MATR380830.008-0.0009No
55FLRT1FLRT181460.008-0.0021No
56ATP1A3ATP1A383910.007-0.0119No
57CDKN1BCDKN1B84920.007-0.0151No
58TMEM35TMEM3586010.007-0.0188No
59KIF21BKIF21B87870.006-0.0261No
60EPB41EPB4188440.006-0.0275No
61ABATABAT91250.005-0.0396No
62KLRK1KLRK191470.005-0.0396No
63C6orf134C6orf13492640.004-0.0440No
64ZNF248ZNF24893180.004-0.0456No
65PFN2PFN294450.004-0.0507No
66PURGPURG95220.004-0.0535No
67SNX26SNX2695290.004-0.0530No
68MCM10MCM1095650.003-0.0539No
69CLGNCLGN95850.003-0.0541No
70SOX10SOX1097610.003-0.0617No
71ZNF711ZNF71197860.003-0.0622No
72CDC25ACDC25A97880.003-0.0617No
73CASKCASK98900.002-0.0659No
74RALGPS2RALGPS299340.002-0.0675No
75CA10CA1099720.002-0.0688No
76CHD7CHD799740.002-0.0684No
77AOF2AOF299900.002-0.0686No
78KLRC3KLRC3100080.002-0.0690No
79STMN1STMN1100270.002-0.0695No
80MARCKSMARCKS100360.002-0.0694No
81WASF1WASF1100410.002-0.0692No
82SATB1SATB1100950.002-0.0714No
83DGKIDGKI101080.002-0.0716No
84RALGPS1RALGPS1102030.001-0.0757No
85TAF5TAF5104190.001-0.0855No
86FAM125BFAM125B104900.001-0.0887No
87RUFY3RUFY3105560.000-0.0917No
88PELI1PELI110697-0.000-0.0982No
89TSPAN3TSPAN310699-0.000-0.0982No
90MMP15MMP1511307-0.002-0.1261No
91IL1RAPL1IL1RAPL111319-0.002-0.1262No
92CDC7CDC711332-0.002-0.1263No
93FAM110BFAM110B11490-0.003-0.1330No
94PCDH11XPCDH11X11637-0.003-0.1392No
95NRXN1NRXN111758-0.004-0.1440No
96ZNF643ZNF64311822-0.004-0.1462No
97MYO10MYO1011837-0.004-0.1460No
98TMCC1TMCC111903-0.004-0.1482No
99MAPTMAPT12192-0.005-0.1606No
100SORCS3SORCS312363-0.006-0.1673No
101PLCB4PLCB412472-0.006-0.1711No
102P2RX7P2RX712774-0.007-0.1837No
103STMN4STMN412976-0.008-0.1914No
104PDE10APDE10A12988-0.008-0.1903No
105MYBMYB13495-0.009-0.2120No
106SCN3ASCN3A13980-0.011-0.2323No
107MAP2MAP214012-0.011-0.2314No
108LRP6LRP614070-0.011-0.2317No
109HMGB3HMGB314202-0.012-0.2353No
110TMEM118TMEM11814294-0.012-0.2370No
111SOX2SOX214311-0.012-0.2352No
112ERBB3ERBB314471-0.013-0.2399No
113YPEL1YPEL114618-0.013-0.2439No
114DPF1DPF114715-0.014-0.2455No
115HRASLSHRASLS14793-0.014-0.2461No
116MYT1MYT115328-0.016-0.2677No
117ZNF804AZNF804A15432-0.017-0.2690No
118EPHB1EPHB115812-0.018-0.2828No
119AMOTL2AMOTL216000-0.019-0.2875No
120REEP1REEP116058-0.019-0.2861No
121HN1HN116160-0.020-0.2867No
122CRMP1CRMP116380-0.021-0.2925No
123TOX3TOX316422-0.021-0.2900No
124PPM1EPPM1E16519-0.021-0.2899No
125MARCKSL1MARCKSL116590-0.022-0.2886No
126CDK5R1CDK5R116855-0.023-0.2961No
127NR0B1NR0B116982-0.024-0.2970No
128CKBCKB17020-0.024-0.2937No
129DPYSL4DPYSL417265-0.025-0.2998No
130SEC61A2SEC61A217540-0.026-0.3070No
131CRB1CRB117541-0.026-0.3015No
132C1orf106C1orf10617766-0.028-0.3061No
133CSNK1ECSNK1E17942-0.029-0.3081No
134RBPJRBPJ18142-0.030-0.3111Yes
135MAST1MAST118212-0.030-0.3079Yes
136DUSP26DUSP2618351-0.031-0.3077Yes
137PAFAH1B3PAFAH1B318371-0.031-0.3020Yes
138ICKICK18543-0.032-0.3031Yes
139MYST2MYST218726-0.034-0.3045Yes
140PODXL2PODXL218990-0.035-0.3093Yes
141WDR68WDR6818992-0.035-0.3019Yes
142ARHGEF9ARHGEF919238-0.037-0.3054Yes
143BAI3BAI319366-0.038-0.3033Yes
144PHF16PHF1619395-0.039-0.2964Yes
145GPR17GPR1719501-0.039-0.2930Yes
146VAX2VAX219506-0.039-0.2849Yes
147RAB33ARAB33A19565-0.040-0.2791Yes
148TMEFF1TMEFF119736-0.041-0.2783Yes
149GNG4GNG419883-0.043-0.2760Yes
150C1QL1C1QL119916-0.044-0.2683Yes
151BEX1BEX120002-0.045-0.2629Yes
152NLGN3NLGN320159-0.046-0.2604Yes
153BCANBCAN20254-0.048-0.2547Yes
154PPM1DPPM1D20267-0.048-0.2452Yes
155MTSS1MTSS120289-0.048-0.2360Yes
156SOX4SOX420350-0.049-0.2285Yes
157GRIA2GRIA220478-0.051-0.2236Yes
158NCALDNCALD21072-0.065-0.2376Yes
159OLIG2OLIG221293-0.075-0.2321Yes
160FXYD6FXYD621404-0.084-0.2196Yes
161GSTA4GSTA421457-0.091-0.2028Yes
162SCG3SCG321484-0.096-0.1838Yes
163DLL3DLL321526-0.105-0.1636Yes
164CSPG5CSPG521531-0.108-0.1410Yes
165TTYH1TTYH121573-0.137-0.1140Yes
166GADD45GGADD45G21585-0.158-0.0812Yes
167C1orf61C1orf6121592-0.181-0.0433Yes
168ASCL1ASCL121596-0.2060.0000Yes
Table: GSEA details [plain text format]



Fig 2: VERHAAK_PN_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_PN_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_PN_2010