DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshCtrl
GeneSetVERHAAK_NEU_2010
Enrichment Score (ES)-0.25262275
Normalized Enrichment Score (NES)-1.0977135
Nominal p-value0.25906736
FDR q-value0.38658342
FWER p-Value0.998
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_NEU_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1BASP1BASP11360.0840.0198No
2EDIL3EDIL31690.0800.0433No
3KIAA1598KIAA15983610.0670.0553No
4ANKRD46ANKRD464120.0650.0732No
5MBPMBP7410.0550.0751No
6EPB41L3EPB41L37640.0550.0911No
7USP33USP339370.0520.0992No
8PPP2R5APPP2R5A14980.0430.0865No
9FEZF2FEZF215950.0420.0952No
10MYBPC1MYBPC116650.0420.1050No
11MAT2BMAT2B17150.0410.1155No
12BCAS1BCAS120690.0380.1108No
13SPASTSPAST20720.0380.1225No
14ADD3ADD322140.0370.1273No
15CCKCCK25390.0340.1228No
16PARP8PARP826340.0330.1288No
17MMDMMD28160.0320.1304No
18FBXO3FBXO331120.0300.1260No
19VIPVIP31420.0300.1340No
20DYNC1I1DYNC1I131960.0300.1407No
21YPEL5YPEL536390.0270.1285No
22HPCAL4HPCAL436970.0270.1341No
23CPNE6CPNE638370.0260.1357No
24CRYZL1CRYZL139900.0250.1364No
25SNCGSNCG40860.0250.1396No
26MORF4L2MORF4L243340.0230.1353No
27AGTPBP1AGTPBP145180.0220.1338No
28SLCO1A2SLCO1A246120.0220.1363No
29DHRS9DHRS955820.0180.0966No
30EVI2AEVI2A56340.0170.0996No
31IMPA1IMPA156620.0170.1037No
32PLCL1PLCL159240.0160.0966No
33CRYMCRYM62730.0150.0849No
34PPFIA2PPFIA265290.0140.0773No
35TSNAXTSNAX65720.0140.0796No
36GNAI1GNAI169980.0120.0635No
37CASQ1CASQ175790.0100.0396No
38SLC30A10SLC30A1075890.0100.0422No
39PEX19PEX1976430.0100.0428No
40TMEM144TMEM14476760.0100.0443No
41HPRT1HPRT177060.0100.0459No
42HPCAHPCA77340.0090.0476No
43SLC31A2SLC31A278550.0090.0448No
44PEX11BPEX11B81920.0080.0316No
45SAR1ASAR1A87040.0060.0098No
46ORC4LORC4L88600.0060.0043No
47SIRT5SIRT588620.0060.0061No
48PSCD1PSCD192790.004-0.0120No
49SNX11SNX1192830.004-0.0108No
50SH3GL3SH3GL393330.004-0.0117No
51ANXA3ANXA395200.004-0.0193No
52ENPP4ENPP495210.004-0.0182No
53GPR22GPR2297770.003-0.0292No
54REPS2REPS299370.002-0.0359No
55ENPP2ENPP299840.002-0.0374No
56SLC16A7SLC16A7100690.002-0.0408No
57ANXA7ANXA7103950.001-0.0557No
58FAM49BFAM49B10790-0.000-0.0739No
59THTPATHTPA10865-0.001-0.0771No
60ZNF323ZNF32311006-0.001-0.0833No
61EDG1EDG111045-0.001-0.0847No
62CUTCCUTC11428-0.002-0.1017No
63FUT9FUT911437-0.003-0.1013No
64ACSL4ACSL411692-0.003-0.1121No
65KCNK1KCNK111747-0.004-0.1135No
66CHN1CHN112022-0.004-0.1249No
67SEPP1SEPP112146-0.005-0.1291No
68GABRB2GABRB212157-0.005-0.1280No
69UGT8UGT812182-0.005-0.1276No
70GRM3GRM312517-0.006-0.1413No
71TTC1TTC112623-0.006-0.1442No
72PPA1PPA112702-0.007-0.1457No
73NTSR2NTSR212778-0.007-0.1471No
74BEST1BEST112800-0.007-0.1459No
75ANKS1BANKS1B12848-0.007-0.1458No
76MDH1MDH112859-0.007-0.1441No
77MGC72080MGC7208013033-0.008-0.1497No
78ATRNL1ATRNL113338-0.009-0.1611No
79PGBD5PGBD513582-0.010-0.1695No
80NDRG2NDRG213872-0.011-0.1797No
81ATP5LATP5L13996-0.011-0.1820No
82ATP5F1ATP5F114275-0.012-0.1912No
83CLCA4CLCA414478-0.013-0.1967No
84CALM2CALM214676-0.014-0.2016No
85FXYD1FXYD114877-0.014-0.2065No
86FHITFHIT15288-0.016-0.2207No
87VSX1VSX115594-0.017-0.2295No
88CCDC121CCDC12116091-0.019-0.2466Yes
89AKR7A3AKR7A316167-0.020-0.2440Yes
90CDR1CDR116240-0.020-0.2411Yes
91KCNJ3KCNJ316394-0.021-0.2417Yes
92SGK3SGK316412-0.021-0.2360Yes
93LYRM1LYRM116576-0.022-0.2369Yes
94PPP1R1APPP1R1A16579-0.022-0.2302Yes
95POPDC3POPDC316588-0.022-0.2238Yes
96NSL1NSL116698-0.022-0.2220Yes
97SERPINI1SERPINI116810-0.023-0.2201Yes
98CRBNCRBN16841-0.023-0.2144Yes
99GABARAPL2GABARAPL216890-0.023-0.2094Yes
100NANOS1NANOS116932-0.023-0.2041Yes
101RND1RND117096-0.024-0.2042Yes
102TTPATTPA17957-0.029-0.2353Yes
103ARRB1ARRB118099-0.030-0.2326Yes
104CDC42CDC4218129-0.030-0.2247Yes
105GRM1GRM118251-0.031-0.2208Yes
106SCHIP1SCHIP118694-0.033-0.2311Yes
107TPM3TPM318933-0.035-0.2313Yes
108CRYL1CRYL118993-0.036-0.2230Yes
109NDUFS3NDUFS319331-0.038-0.2269Yes
110GUK1GUK119496-0.039-0.2223Yes
111CAMK2GCAMK2G20011-0.045-0.2324Yes
112COX5BCOX5B20105-0.046-0.2226Yes
113MAGEH1MAGEH120147-0.046-0.2101Yes
114PDE6DPDE6D20310-0.048-0.2027Yes
115TCEAL1TCEAL120313-0.048-0.1877Yes
116MRPL49MRPL4920393-0.050-0.1760Yes
117TCEAL2TCEAL220439-0.050-0.1625Yes
118SEPW1SEPW120466-0.051-0.1479Yes
119ROGDIROGDI20589-0.053-0.1372Yes
120PRPSAP2PRPSAP220618-0.054-0.1218Yes
121UROSUROS20643-0.054-0.1061Yes
122AGXT2L1AGXT2L120974-0.062-0.1023Yes
123CA4CA421108-0.066-0.0879Yes
124MGST3MGST321259-0.073-0.0722Yes
125SH3GL2SH3GL221419-0.085-0.0532Yes
126ACYP2ACYP221488-0.096-0.0267Yes
127MSRB2MSRB221513-0.1020.0039Yes
Table: GSEA details [plain text format]



Fig 2: VERHAAK_NEU_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_NEU_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_NEU_2010