Dataset | shNF1_exprs.shNF1_phenotype.cls #shNF1_versus_shCtrl.shNF1_phenotype.cls #shNF1_versus_shCtrl_repos |
Phenotype | shNF1_phenotype.cls#shNF1_versus_shCtrl_repos |
Upregulated in class | shNF1 |
GeneSet | VERHAAK_MES_2010 |
Enrichment Score (ES) | 0.30602142 |
Normalized Enrichment Score (NES) | 1.4981086 |
Nominal p-value | 0.0 |
FDR q-value | 0.018248387 |
FWER p-Value | 0.152 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | LRRFIP1 | LRRFIP1 | 5 | 0.137 | 0.0218 | Yes |
2 | MAN2A1 | MAN2A1 | 12 | 0.125 | 0.0416 | Yes |
3 | THBS1 | THBS1 | 13 | 0.123 | 0.0614 | Yes |
4 | BNC2 | BNC2 | 40 | 0.102 | 0.0766 | Yes |
5 | LAMB1 | LAMB1 | 72 | 0.095 | 0.0904 | Yes |
6 | TGFBR2 | TGFBR2 | 80 | 0.093 | 0.1050 | Yes |
7 | PLAU | PLAU | 94 | 0.090 | 0.1188 | Yes |
8 | COL1A1 | COL1A1 | 158 | 0.082 | 0.1291 | Yes |
9 | ITGA5 | ITGA5 | 208 | 0.077 | 0.1391 | Yes |
10 | ELF4 | ELF4 | 328 | 0.069 | 0.1446 | Yes |
11 | IQGAP1 | IQGAP1 | 378 | 0.067 | 0.1530 | Yes |
12 | DCBLD2 | DCBLD2 | 494 | 0.062 | 0.1576 | Yes |
13 | COL1A2 | COL1A2 | 651 | 0.057 | 0.1595 | Yes |
14 | MVP | MVP | 711 | 0.056 | 0.1657 | Yes |
15 | SH2B3 | SH2B3 | 724 | 0.056 | 0.1741 | Yes |
16 | SERPINE1 | SERPINE1 | 725 | 0.056 | 0.1831 | Yes |
17 | FHOD1 | FHOD1 | 726 | 0.056 | 0.1921 | Yes |
18 | YAP1 | YAP1 | 783 | 0.055 | 0.1982 | Yes |
19 | TCIRG1 | TCIRG1 | 1021 | 0.050 | 0.1952 | Yes |
20 | GCNT1 | GCNT1 | 1093 | 0.049 | 0.1998 | Yes |
21 | FER1L3 | FER1L3 | 1126 | 0.049 | 0.2061 | Yes |
22 | ANXA2 | ANXA2 | 1146 | 0.048 | 0.2129 | Yes |
23 | WWTR1 | WWTR1 | 1155 | 0.048 | 0.2203 | Yes |
24 | CTSZ | CTSZ | 1161 | 0.048 | 0.2277 | Yes |
25 | PTGER4 | PTGER4 | 1207 | 0.047 | 0.2332 | Yes |
26 | CD2AP | CD2AP | 1214 | 0.047 | 0.2405 | Yes |
27 | LOX | LOX | 1391 | 0.045 | 0.2394 | Yes |
28 | TLR4 | TLR4 | 1412 | 0.044 | 0.2456 | Yes |
29 | NRP1 | NRP1 | 1414 | 0.044 | 0.2527 | Yes |
30 | IL4R | IL4R | 1474 | 0.044 | 0.2570 | Yes |
31 | FHL2 | FHL2 | 1493 | 0.043 | 0.2631 | Yes |
32 | CLCF1 | CLCF1 | 1758 | 0.041 | 0.2573 | Yes |
33 | MYH9 | MYH9 | 1778 | 0.041 | 0.2630 | Yes |
34 | SQRDL | SQRDL | 1888 | 0.040 | 0.2642 | Yes |
35 | ZNF217 | ZNF217 | 1934 | 0.039 | 0.2684 | Yes |
36 | PLS3 | PLS3 | 2001 | 0.039 | 0.2715 | Yes |
37 | SYPL1 | SYPL1 | 2107 | 0.038 | 0.2726 | Yes |
38 | FNDC3B | FNDC3B | 2151 | 0.037 | 0.2766 | Yes |
39 | FOLR2 | FOLR2 | 2183 | 0.037 | 0.2811 | Yes |
40 | DOK3 | DOK3 | 2188 | 0.037 | 0.2868 | Yes |
41 | C1orf38 | C1orf38 | 2216 | 0.037 | 0.2915 | Yes |
42 | PTRF | PTRF | 2260 | 0.036 | 0.2953 | Yes |
43 | NCF4 | NCF4 | 2426 | 0.035 | 0.2932 | Yes |
44 | IL15RA | IL15RA | 2486 | 0.035 | 0.2960 | Yes |
45 | SRPX2 | SRPX2 | 2851 | 0.032 | 0.2841 | Yes |
46 | ARHGAP29 | ARHGAP29 | 2887 | 0.032 | 0.2876 | Yes |
47 | SLC16A3 | SLC16A3 | 2914 | 0.032 | 0.2915 | Yes |
48 | SEC24D | SEC24D | 2951 | 0.031 | 0.2948 | Yes |
49 | EFEMP2 | EFEMP2 | 3022 | 0.031 | 0.2965 | Yes |
50 | ACPP | ACPP | 3084 | 0.030 | 0.2985 | Yes |
51 | ADAM12 | ADAM12 | 3114 | 0.030 | 0.3020 | Yes |
52 | ARSJ | ARSJ | 3133 | 0.030 | 0.3060 | Yes |
53 | LCP2 | LCP2 | 3720 | 0.027 | 0.2829 | No |
54 | CAST | CAST | 3894 | 0.026 | 0.2789 | No |
55 | NCF2 | NCF2 | 3940 | 0.025 | 0.2809 | No |
56 | CLEC2B | CLEC2B | 4145 | 0.024 | 0.2752 | No |
57 | PLK3 | PLK3 | 4263 | 0.024 | 0.2735 | No |
58 | GLT25D1 | GLT25D1 | 4708 | 0.022 | 0.2562 | No |
59 | CHI3L1 | CHI3L1 | 4752 | 0.021 | 0.2577 | No |
60 | TGFBI | TGFBI | 4792 | 0.021 | 0.2592 | No |
61 | PSCDBP | PSCDBP | 4800 | 0.021 | 0.2623 | No |
62 | TNFRSF1B | TNFRSF1B | 4866 | 0.021 | 0.2626 | No |
63 | ALOX5 | ALOX5 | 4872 | 0.021 | 0.2658 | No |
64 | HEXB | HEXB | 5023 | 0.020 | 0.2620 | No |
65 | CNN2 | CNN2 | 5091 | 0.020 | 0.2620 | No |
66 | CASP4 | CASP4 | 5106 | 0.020 | 0.2645 | No |
67 | ACSL1 | ACSL1 | 5130 | 0.020 | 0.2666 | No |
68 | FLJ22662 | FLJ22662 | 5151 | 0.020 | 0.2688 | No |
69 | ANXA1 | ANXA1 | 5293 | 0.019 | 0.2653 | No |
70 | FCGR2A | FCGR2A | 5414 | 0.018 | 0.2626 | No |
71 | HFE | HFE | 5423 | 0.018 | 0.2652 | No |
72 | TMBIM1 | TMBIM1 | 5437 | 0.018 | 0.2675 | No |
73 | TNFAIP8 | TNFAIP8 | 5465 | 0.018 | 0.2692 | No |
74 | BATF | BATF | 5532 | 0.018 | 0.2689 | No |
75 | PYGL | PYGL | 5661 | 0.017 | 0.2657 | No |
76 | PTPRC | PTPRC | 5766 | 0.017 | 0.2636 | No |
77 | TRPM2 | TRPM2 | 5773 | 0.017 | 0.2660 | No |
78 | CTSC | CTSC | 6083 | 0.016 | 0.2540 | No |
79 | MGAT1 | MGAT1 | 6097 | 0.015 | 0.2559 | No |
80 | CD14 | CD14 | 6129 | 0.015 | 0.2569 | No |
81 | ARPC1B | ARPC1B | 6192 | 0.015 | 0.2565 | No |
82 | RAB27A | RAB27A | 6204 | 0.015 | 0.2584 | No |
83 | CD4 | CD4 | 6236 | 0.015 | 0.2593 | No |
84 | CDCP1 | CDCP1 | 6238 | 0.015 | 0.2616 | No |
85 | EHD2 | EHD2 | 6388 | 0.014 | 0.2570 | No |
86 | PSCD4 | PSCD4 | 6567 | 0.014 | 0.2508 | No |
87 | FLJ20273 | FLJ20273 | 6600 | 0.013 | 0.2515 | No |
88 | P4HA2 | P4HA2 | 7058 | 0.012 | 0.2320 | No |
89 | TES | TES | 7144 | 0.011 | 0.2299 | No |
90 | ALDH3B1 | ALDH3B1 | 7262 | 0.011 | 0.2262 | No |
91 | BDKRB2 | BDKRB2 | 7310 | 0.011 | 0.2257 | No |
92 | LHFPL2 | LHFPL2 | 7435 | 0.010 | 0.2216 | No |
93 | CYBRD1 | CYBRD1 | 7442 | 0.010 | 0.2230 | No |
94 | RBMS1 | RBMS1 | 7443 | 0.010 | 0.2247 | No |
95 | PLAUR | PLAUR | 7477 | 0.010 | 0.2248 | No |
96 | HEXA | HEXA | 7556 | 0.010 | 0.2228 | No |
97 | DSC2 | DSC2 | 7848 | 0.009 | 0.2106 | No |
98 | MYO1F | MYO1F | 7975 | 0.009 | 0.2061 | No |
99 | SHC1 | SHC1 | 8045 | 0.008 | 0.2042 | No |
100 | LILRB3 | LILRB3 | 8107 | 0.008 | 0.2027 | No |
101 | FES | FES | 8143 | 0.008 | 0.2024 | No |
102 | MAN1A1 | MAN1A1 | 8727 | 0.006 | 0.1761 | No |
103 | SLAMF8 | SLAMF8 | 8876 | 0.006 | 0.1701 | No |
104 | AIM1 | AIM1 | 9026 | 0.005 | 0.1640 | No |
105 | SFT2D2 | SFT2D2 | 9107 | 0.005 | 0.1610 | No |
106 | SYNGR2 | SYNGR2 | 9437 | 0.004 | 0.1462 | No |
107 | RHOG | RHOG | 9578 | 0.003 | 0.1402 | No |
108 | LAPTM5 | LAPTM5 | 9604 | 0.003 | 0.1396 | No |
109 | TLR2 | TLR2 | 9702 | 0.003 | 0.1355 | No |
110 | TRIM38 | TRIM38 | 9876 | 0.002 | 0.1278 | No |
111 | SLC11A1 | SLC11A1 | 9885 | 0.002 | 0.1278 | No |
112 | TGOLN2 | TGOLN2 | 9931 | 0.002 | 0.1261 | No |
113 | HK3 | HK3 | 9971 | 0.002 | 0.1246 | No |
114 | UAP1 | UAP1 | 10169 | 0.001 | 0.1156 | No |
115 | GNA15 | GNA15 | 10507 | 0.000 | 0.0999 | No |
116 | CSTA | CSTA | 10682 | -0.000 | 0.0918 | No |
117 | S100A11 | S100A11 | 10703 | -0.000 | 0.0909 | No |
118 | LAIR1 | LAIR1 | 10798 | -0.000 | 0.0866 | No |
119 | LGALS1 | LGALS1 | 11128 | -0.001 | 0.0714 | No |
120 | PTPN6 | PTPN6 | 11227 | -0.002 | 0.0671 | No |
121 | NOD2 | NOD2 | 11272 | -0.002 | 0.0654 | No |
122 | SWAP70 | SWAP70 | 11405 | -0.002 | 0.0596 | No |
123 | LILRB2 | LILRB2 | 11421 | -0.002 | 0.0593 | No |
124 | FCGR2B | FCGR2B | 11499 | -0.003 | 0.0561 | No |
125 | CLIC1 | CLIC1 | 11509 | -0.003 | 0.0561 | No |
126 | MRC2 | MRC2 | 11609 | -0.003 | 0.0520 | No |
127 | LCP1 | LCP1 | 11622 | -0.003 | 0.0519 | No |
128 | ENG | ENG | 11938 | -0.004 | 0.0379 | No |
129 | LTBP2 | LTBP2 | 11962 | -0.004 | 0.0375 | No |
130 | PDPN | PDPN | 11998 | -0.004 | 0.0365 | No |
131 | C5AR1 | C5AR1 | 12203 | -0.005 | 0.0278 | No |
132 | STXBP2 | STXBP2 | 12501 | -0.006 | 0.0149 | No |
133 | CTSB | CTSB | 12661 | -0.007 | 0.0085 | No |
134 | LY75 | LY75 | 12816 | -0.007 | 0.0025 | No |
135 | CASP8 | CASP8 | 12893 | -0.007 | 0.0001 | No |
136 | LTBP1 | LTBP1 | 13035 | -0.008 | -0.0053 | No |
137 | RUNX2 | RUNX2 | 13175 | -0.008 | -0.0105 | No |
138 | CASP1 | CASP1 | 13302 | -0.009 | -0.0149 | No |
139 | ITGA4 | ITGA4 | 13362 | -0.009 | -0.0163 | No |
140 | AMPD3 | AMPD3 | 13388 | -0.009 | -0.0160 | No |
141 | S100A13 | S100A13 | 13428 | -0.009 | -0.0164 | No |
142 | TEC | TEC | 13487 | -0.009 | -0.0176 | No |
143 | STAT6 | STAT6 | 13627 | -0.010 | -0.0226 | No |
144 | SCPEP1 | SCPEP1 | 13899 | -0.011 | -0.0335 | No |
145 | ITGB2 | ITGB2 | 13986 | -0.011 | -0.0358 | No |
146 | PROCR | PROCR | 14056 | -0.011 | -0.0372 | No |
147 | COL5A1 | COL5A1 | 14074 | -0.011 | -0.0362 | No |
148 | COL8A2 | COL8A2 | 14151 | -0.012 | -0.0379 | No |
149 | CCDC109B | CCDC109B | 14261 | -0.012 | -0.0410 | No |
150 | LY96 | LY96 | 14269 | -0.012 | -0.0394 | No |
151 | ANXA4 | ANXA4 | 14631 | -0.013 | -0.0542 | No |
152 | TRADD | TRADD | 14833 | -0.014 | -0.0613 | No |
153 | FXYD5 | FXYD5 | 14924 | -0.014 | -0.0632 | No |
154 | FURIN | FURIN | 15012 | -0.015 | -0.0649 | No |
155 | DAB2 | DAB2 | 15121 | -0.015 | -0.0675 | No |
156 | PGCP | PGCP | 15177 | -0.016 | -0.0675 | No |
157 | MAPK13 | MAPK13 | 15279 | -0.016 | -0.0697 | No |
158 | UCP2 | UCP2 | 15449 | -0.017 | -0.0749 | No |
159 | MSR1 | MSR1 | 15535 | -0.017 | -0.0762 | No |
160 | CASP5 | CASP5 | 15558 | -0.017 | -0.0744 | No |
161 | POLD4 | POLD4 | 15599 | -0.017 | -0.0735 | No |
162 | ASL | ASL | 15697 | -0.018 | -0.0752 | No |
163 | STAB1 | STAB1 | 15860 | -0.018 | -0.0799 | No |
164 | ST14 | ST14 | 15998 | -0.019 | -0.0832 | No |
165 | TIMP1 | TIMP1 | 16033 | -0.019 | -0.0817 | No |
166 | SIGLEC7 | SIGLEC7 | 16107 | -0.019 | -0.0820 | No |
167 | DSE | DSE | 16192 | -0.020 | -0.0827 | No |
168 | SERPINA1 | SERPINA1 | 16362 | -0.021 | -0.0873 | No |
169 | EMP3 | EMP3 | 16399 | -0.021 | -0.0857 | No |
170 | MGST2 | MGST2 | 16668 | -0.022 | -0.0946 | No |
171 | MFSD1 | MFSD1 | 16964 | -0.023 | -0.1047 | No |
172 | WIPF1 | WIPF1 | 17056 | -0.024 | -0.1051 | No |
173 | SIGLEC9 | SIGLEC9 | 17366 | -0.025 | -0.1154 | No |
174 | CCR5 | CCR5 | 17404 | -0.026 | -0.1130 | No |
175 | VDR | VDR | 17575 | -0.027 | -0.1167 | No |
176 | ITGAM | ITGAM | 17946 | -0.029 | -0.1294 | No |
177 | MS4A4A | MS4A4A | 18007 | -0.029 | -0.1275 | No |
178 | PTPN22 | PTPN22 | 18066 | -0.030 | -0.1254 | No |
179 | TNFAIP3 | TNFAIP3 | 18220 | -0.030 | -0.1277 | No |
180 | TRIM22 | TRIM22 | 18283 | -0.031 | -0.1256 | No |
181 | TNFRSF1A | TNFRSF1A | 18376 | -0.031 | -0.1249 | No |
182 | SAT1 | SAT1 | 18435 | -0.032 | -0.1225 | No |
183 | RELB | RELB | 18625 | -0.033 | -0.1260 | No |
184 | MAFB | MAFB | 18670 | -0.033 | -0.1228 | No |
185 | COPZ2 | COPZ2 | 19095 | -0.036 | -0.1368 | No |
186 | RABGAP1L | RABGAP1L | 19333 | -0.038 | -0.1417 | No |
187 | KYNU | KYNU | 19528 | -0.040 | -0.1444 | No |
188 | THBD | THBD | 19532 | -0.040 | -0.1382 | No |
189 | IL1R1 | IL1R1 | 19546 | -0.040 | -0.1324 | No |
190 | FMNL1 | FMNL1 | 19627 | -0.041 | -0.1297 | No |
191 | SLC10A3 | SLC10A3 | 19679 | -0.041 | -0.1255 | No |
192 | RAB11FIP1 | RAB11FIP1 | 19728 | -0.041 | -0.1211 | No |
193 | RAB32 | RAB32 | 19768 | -0.042 | -0.1162 | No |
194 | GRN | GRN | 19813 | -0.042 | -0.1114 | No |
195 | MAN2B1 | MAN2B1 | 20031 | -0.045 | -0.1144 | No |
196 | SP100 | SP100 | 20037 | -0.045 | -0.1074 | No |
197 | S100A4 | S100A4 | 20089 | -0.046 | -0.1024 | No |
198 | NPC2 | NPC2 | 20205 | -0.047 | -0.1003 | No |
199 | TNFRSF11A | TNFRSF11A | 20262 | -0.048 | -0.0953 | No |
200 | RRAS | RRAS | 20323 | -0.049 | -0.0903 | No |
201 | PHF11 | PHF11 | 20428 | -0.050 | -0.0871 | No |
202 | PIGP | PIGP | 20442 | -0.050 | -0.0796 | No |
203 | IFI30 | IFI30 | 20457 | -0.051 | -0.0721 | No |
204 | VAMP5 | VAMP5 | 20551 | -0.052 | -0.0680 | No |
205 | RAC2 | RAC2 | 21019 | -0.063 | -0.0797 | No |
206 | RBKS | RBKS | 21065 | -0.065 | -0.0714 | No |
207 | BLVRB | BLVRB | 21104 | -0.066 | -0.0625 | No |
208 | ICAM3 | ICAM3 | 21189 | -0.070 | -0.0553 | No |
209 | LGALS3 | LGALS3 | 21310 | -0.076 | -0.0487 | No |
210 | ECGF1 | ECGF1 | 21391 | -0.082 | -0.0392 | No |
211 | CEBPB | CEBPB | 21428 | -0.086 | -0.0270 | No |
212 | IGFBP6 | IGFBP6 | 21454 | -0.091 | -0.0135 | No |
213 | C1orf54 | C1orf54 | 21561 | -0.125 | 0.0016 | No |