DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetVERHAAK_MES_2010
Enrichment Score (ES)0.30602142
Normalized Enrichment Score (NES)1.4981086
Nominal p-value0.0
FDR q-value0.018248387
FWER p-Value0.152
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_MES_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LRRFIP1LRRFIP150.1370.0218Yes
2MAN2A1MAN2A1120.1250.0416Yes
3THBS1THBS1130.1230.0614Yes
4BNC2BNC2400.1020.0766Yes
5LAMB1LAMB1720.0950.0904Yes
6TGFBR2TGFBR2800.0930.1050Yes
7PLAUPLAU940.0900.1188Yes
8COL1A1COL1A11580.0820.1291Yes
9ITGA5ITGA52080.0770.1391Yes
10ELF4ELF43280.0690.1446Yes
11IQGAP1IQGAP13780.0670.1530Yes
12DCBLD2DCBLD24940.0620.1576Yes
13COL1A2COL1A26510.0570.1595Yes
14MVPMVP7110.0560.1657Yes
15SH2B3SH2B37240.0560.1741Yes
16SERPINE1SERPINE17250.0560.1831Yes
17FHOD1FHOD17260.0560.1921Yes
18YAP1YAP17830.0550.1982Yes
19TCIRG1TCIRG110210.0500.1952Yes
20GCNT1GCNT110930.0490.1998Yes
21FER1L3FER1L311260.0490.2061Yes
22ANXA2ANXA211460.0480.2129Yes
23WWTR1WWTR111550.0480.2203Yes
24CTSZCTSZ11610.0480.2277Yes
25PTGER4PTGER412070.0470.2332Yes
26CD2APCD2AP12140.0470.2405Yes
27LOXLOX13910.0450.2394Yes
28TLR4TLR414120.0440.2456Yes
29NRP1NRP114140.0440.2527Yes
30IL4RIL4R14740.0440.2570Yes
31FHL2FHL214930.0430.2631Yes
32CLCF1CLCF117580.0410.2573Yes
33MYH9MYH917780.0410.2630Yes
34SQRDLSQRDL18880.0400.2642Yes
35ZNF217ZNF21719340.0390.2684Yes
36PLS3PLS320010.0390.2715Yes
37SYPL1SYPL121070.0380.2726Yes
38FNDC3BFNDC3B21510.0370.2766Yes
39FOLR2FOLR221830.0370.2811Yes
40DOK3DOK321880.0370.2868Yes
41C1orf38C1orf3822160.0370.2915Yes
42PTRFPTRF22600.0360.2953Yes
43NCF4NCF424260.0350.2932Yes
44IL15RAIL15RA24860.0350.2960Yes
45SRPX2SRPX228510.0320.2841Yes
46ARHGAP29ARHGAP2928870.0320.2876Yes
47SLC16A3SLC16A329140.0320.2915Yes
48SEC24DSEC24D29510.0310.2948Yes
49EFEMP2EFEMP230220.0310.2965Yes
50ACPPACPP30840.0300.2985Yes
51ADAM12ADAM1231140.0300.3020Yes
52ARSJARSJ31330.0300.3060Yes
53LCP2LCP237200.0270.2829No
54CASTCAST38940.0260.2789No
55NCF2NCF239400.0250.2809No
56CLEC2BCLEC2B41450.0240.2752No
57PLK3PLK342630.0240.2735No
58GLT25D1GLT25D147080.0220.2562No
59CHI3L1CHI3L147520.0210.2577No
60TGFBITGFBI47920.0210.2592No
61PSCDBPPSCDBP48000.0210.2623No
62TNFRSF1BTNFRSF1B48660.0210.2626No
63ALOX5ALOX548720.0210.2658No
64HEXBHEXB50230.0200.2620No
65CNN2CNN250910.0200.2620No
66CASP4CASP451060.0200.2645No
67ACSL1ACSL151300.0200.2666No
68FLJ22662FLJ2266251510.0200.2688No
69ANXA1ANXA152930.0190.2653No
70FCGR2AFCGR2A54140.0180.2626No
71HFEHFE54230.0180.2652No
72TMBIM1TMBIM154370.0180.2675No
73TNFAIP8TNFAIP854650.0180.2692No
74BATFBATF55320.0180.2689No
75PYGLPYGL56610.0170.2657No
76PTPRCPTPRC57660.0170.2636No
77TRPM2TRPM257730.0170.2660No
78CTSCCTSC60830.0160.2540No
79MGAT1MGAT160970.0150.2559No
80CD14CD1461290.0150.2569No
81ARPC1BARPC1B61920.0150.2565No
82RAB27ARAB27A62040.0150.2584No
83CD4CD462360.0150.2593No
84CDCP1CDCP162380.0150.2616No
85EHD2EHD263880.0140.2570No
86PSCD4PSCD465670.0140.2508No
87FLJ20273FLJ2027366000.0130.2515No
88P4HA2P4HA270580.0120.2320No
89TESTES71440.0110.2299No
90ALDH3B1ALDH3B172620.0110.2262No
91BDKRB2BDKRB273100.0110.2257No
92LHFPL2LHFPL274350.0100.2216No
93CYBRD1CYBRD174420.0100.2230No
94RBMS1RBMS174430.0100.2247No
95PLAURPLAUR74770.0100.2248No
96HEXAHEXA75560.0100.2228No
97DSC2DSC278480.0090.2106No
98MYO1FMYO1F79750.0090.2061No
99SHC1SHC180450.0080.2042No
100LILRB3LILRB381070.0080.2027No
101FESFES81430.0080.2024No
102MAN1A1MAN1A187270.0060.1761No
103SLAMF8SLAMF888760.0060.1701No
104AIM1AIM190260.0050.1640No
105SFT2D2SFT2D291070.0050.1610No
106SYNGR2SYNGR294370.0040.1462No
107RHOGRHOG95780.0030.1402No
108LAPTM5LAPTM596040.0030.1396No
109TLR2TLR297020.0030.1355No
110TRIM38TRIM3898760.0020.1278No
111SLC11A1SLC11A198850.0020.1278No
112TGOLN2TGOLN299310.0020.1261No
113HK3HK399710.0020.1246No
114UAP1UAP1101690.0010.1156No
115GNA15GNA15105070.0000.0999No
116CSTACSTA10682-0.0000.0918No
117S100A11S100A1110703-0.0000.0909No
118LAIR1LAIR110798-0.0000.0866No
119LGALS1LGALS111128-0.0010.0714No
120PTPN6PTPN611227-0.0020.0671No
121NOD2NOD211272-0.0020.0654No
122SWAP70SWAP7011405-0.0020.0596No
123LILRB2LILRB211421-0.0020.0593No
124FCGR2BFCGR2B11499-0.0030.0561No
125CLIC1CLIC111509-0.0030.0561No
126MRC2MRC211609-0.0030.0520No
127LCP1LCP111622-0.0030.0519No
128ENGENG11938-0.0040.0379No
129LTBP2LTBP211962-0.0040.0375No
130PDPNPDPN11998-0.0040.0365No
131C5AR1C5AR112203-0.0050.0278No
132STXBP2STXBP212501-0.0060.0149No
133CTSBCTSB12661-0.0070.0085No
134LY75LY7512816-0.0070.0025No
135CASP8CASP812893-0.0070.0001No
136LTBP1LTBP113035-0.008-0.0053No
137RUNX2RUNX213175-0.008-0.0105No
138CASP1CASP113302-0.009-0.0149No
139ITGA4ITGA413362-0.009-0.0163No
140AMPD3AMPD313388-0.009-0.0160No
141S100A13S100A1313428-0.009-0.0164No
142TECTEC13487-0.009-0.0176No
143STAT6STAT613627-0.010-0.0226No
144SCPEP1SCPEP113899-0.011-0.0335No
145ITGB2ITGB213986-0.011-0.0358No
146PROCRPROCR14056-0.011-0.0372No
147COL5A1COL5A114074-0.011-0.0362No
148COL8A2COL8A214151-0.012-0.0379No
149CCDC109BCCDC109B14261-0.012-0.0410No
150LY96LY9614269-0.012-0.0394No
151ANXA4ANXA414631-0.013-0.0542No
152TRADDTRADD14833-0.014-0.0613No
153FXYD5FXYD514924-0.014-0.0632No
154FURINFURIN15012-0.015-0.0649No
155DAB2DAB215121-0.015-0.0675No
156PGCPPGCP15177-0.016-0.0675No
157MAPK13MAPK1315279-0.016-0.0697No
158UCP2UCP215449-0.017-0.0749No
159MSR1MSR115535-0.017-0.0762No
160CASP5CASP515558-0.017-0.0744No
161POLD4POLD415599-0.017-0.0735No
162ASLASL15697-0.018-0.0752No
163STAB1STAB115860-0.018-0.0799No
164ST14ST1415998-0.019-0.0832No
165TIMP1TIMP116033-0.019-0.0817No
166SIGLEC7SIGLEC716107-0.019-0.0820No
167DSEDSE16192-0.020-0.0827No
168SERPINA1SERPINA116362-0.021-0.0873No
169EMP3EMP316399-0.021-0.0857No
170MGST2MGST216668-0.022-0.0946No
171MFSD1MFSD116964-0.023-0.1047No
172WIPF1WIPF117056-0.024-0.1051No
173SIGLEC9SIGLEC917366-0.025-0.1154No
174CCR5CCR517404-0.026-0.1130No
175VDRVDR17575-0.027-0.1167No
176ITGAMITGAM17946-0.029-0.1294No
177MS4A4AMS4A4A18007-0.029-0.1275No
178PTPN22PTPN2218066-0.030-0.1254No
179TNFAIP3TNFAIP318220-0.030-0.1277No
180TRIM22TRIM2218283-0.031-0.1256No
181TNFRSF1ATNFRSF1A18376-0.031-0.1249No
182SAT1SAT118435-0.032-0.1225No
183RELBRELB18625-0.033-0.1260No
184MAFBMAFB18670-0.033-0.1228No
185COPZ2COPZ219095-0.036-0.1368No
186RABGAP1LRABGAP1L19333-0.038-0.1417No
187KYNUKYNU19528-0.040-0.1444No
188THBDTHBD19532-0.040-0.1382No
189IL1R1IL1R119546-0.040-0.1324No
190FMNL1FMNL119627-0.041-0.1297No
191SLC10A3SLC10A319679-0.041-0.1255No
192RAB11FIP1RAB11FIP119728-0.041-0.1211No
193RAB32RAB3219768-0.042-0.1162No
194GRNGRN19813-0.042-0.1114No
195MAN2B1MAN2B120031-0.045-0.1144No
196SP100SP10020037-0.045-0.1074No
197S100A4S100A420089-0.046-0.1024No
198NPC2NPC220205-0.047-0.1003No
199TNFRSF11ATNFRSF11A20262-0.048-0.0953No
200RRASRRAS20323-0.049-0.0903No
201PHF11PHF1120428-0.050-0.0871No
202PIGPPIGP20442-0.050-0.0796No
203IFI30IFI3020457-0.051-0.0721No
204VAMP5VAMP520551-0.052-0.0680No
205RAC2RAC221019-0.063-0.0797No
206RBKSRBKS21065-0.065-0.0714No
207BLVRBBLVRB21104-0.066-0.0625No
208ICAM3ICAM321189-0.070-0.0553No
209LGALS3LGALS321310-0.076-0.0487No
210ECGF1ECGF121391-0.082-0.0392No
211CEBPBCEBPB21428-0.086-0.0270No
212IGFBP6IGFBP621454-0.091-0.0135No
213C1orf54C1orf5421561-0.1250.0016No
Table: GSEA details [plain text format]



Fig 2: VERHAAK_MES_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_MES_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_MES_2010