DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshCtrl
GeneSetVDR_REGULON
Enrichment Score (ES)-0.18814127
Normalized Enrichment Score (NES)-0.844639
Nominal p-value0.8446281
FDR q-value0.8173369
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: VDR_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PI15PI15100.1290.0367No
2DENND3DENND31030.0880.0580No
3ME1ME13380.0680.0668No
4S100A8S100A85460.0600.0745No
5NAV3NAV35470.0600.0918No
6TNFSF9TNFSF96380.0580.1042No
7ABCA7ABCA79780.0510.1031No
8TCIRG1TCIRG110210.0500.1157No
9GPR39GPR3910400.0500.1292No
10GCNT1GCNT110930.0490.1410No
11TFAP2CTFAP2C16250.0420.1284No
12SERPINB7SERPINB717420.0410.1348No
13IL15RAIL15RA24860.0350.1102No
14ZFRZFR26940.0330.1101No
15TNNT1TNNT127960.0320.1147No
16MPZMPZ28120.0320.1233No
17SMARCD2SMARCD228570.0320.1305No
18DCAF7DCAF730010.0310.1327No
19STX11STX1133200.0290.1262No
20UBE2ZUBE2Z33590.0290.1327No
21CXCL3CXCL334330.0280.1375No
22CPPED1CPPED134340.0280.1456No
23SOX11SOX1135150.0280.1499No
24MSX2MSX235530.0280.1561No
25GALNT6GALNT636110.0270.1613No
26CD55CD5537960.0260.1602No
27RAD50RAD5038170.0260.1668No
28STEAP3STEAP339300.0250.1689No
29STARD5STARD542840.0240.1593No
30AOX1AOX148150.0210.1406No
31LAMC2LAMC249720.0200.1392No
32TMEM40TMEM4050590.0200.1410No
33CASP4CASP451060.0200.1446No
34IPPKIPPK55600.0180.1285No
35EVI2AEVI2A56340.0170.1301No
36RAB27ARAB27A62040.0150.1080No
37CDCP1CDCP162380.0150.1107No
38HPCAL1HPCAL162810.0150.1130No
39COL17A1COL17A164030.0140.1114No
40ABLIM3ABLIM364250.0140.1145No
41YWHAEYWHAE65010.0140.1150No
42IQSEC2IQSEC265230.0140.1180No
43ITPR3ITPR368210.0130.1078No
44LTBRLTBR69190.0120.1068No
45BANK1BANK170270.0120.1053No
46C3C371140.0120.1046No
47TGM2TGM271780.0110.1049No
48SH3TC1SH3TC173460.0110.1002No
49AKR1C1AKR1C173620.0110.1026No
50APOL1APOL173680.0110.1055No
51SELPLGSELPLG74030.0110.1069No
52TBX3TBX374130.0110.1096No
53LLGL2LLGL276510.0100.1013No
54ACSL5ACSL578320.0090.0956No
55PHF7PHF778700.0090.0964No
56TNFAIP2TNFAIP278990.0090.0977No
57PLP2PLP283800.0070.0774No
58MCOLN3MCOLN386850.0060.0651No
59LRRC8ELRRC8E90250.0050.0508No
60ABATABAT91250.0050.0475No
61VNN1VNN191730.0050.0467No
62TRAPPC10TRAPPC1092230.0040.0457No
63ADRB2ADRB292880.0040.0440No
64ENOX2ENOX293110.0040.0442No
65SYNGR2SYNGR294370.0040.0395No
66ABL2ABL294770.0040.0387No
67FLI1FLI195260.0040.0375No
68ALDH3A1ALDH3A196100.0030.0346No
69PVRPVR96620.0030.0331No
70TRIM38TRIM3898760.0020.0239No
71C16orf71C16orf7198830.0020.0243No
72CHD7CHD799740.0020.0207No
73SRGNSRGN103640.0010.0028No
74PRKCDPRKCD104100.0010.0009No
75TCF12TCF12104380.001-0.0002No
76ASPHASPH106350.000-0.0093No
77MID2MID2106460.000-0.0098No
78TNNC2TNNC210890-0.001-0.0209No
79PRICKLE3PRICKLE310903-0.001-0.0212No
80SP140LSP140L10912-0.001-0.0213No
81PKP3PKP310976-0.001-0.0240No
82CHST15CHST1511178-0.002-0.0329No
83SDC1SDC111233-0.002-0.0349No
84HMGA1HMGA111260-0.002-0.0355No
85HTR7HTR711264-0.002-0.0351No
86DNASE1L1DNASE1L111287-0.002-0.0356No
87TRIM24TRIM2411296-0.002-0.0353No
88GMDSGMDS11353-0.002-0.0373No
89PTPRHPTPRH11396-0.002-0.0386No
90IL15IL1511439-0.003-0.0398No
91CYB5R2CYB5R211635-0.003-0.0480No
92GPRC5AGPRC5A11746-0.004-0.0521No
93ADARB1ADARB111825-0.004-0.0546No
94SPAG1SPAG111852-0.004-0.0547No
95PIK3CDPIK3CD11950-0.004-0.0580No
96LTBP2LTBP211962-0.004-0.0573No
97CDC42EP1CDC42EP112211-0.005-0.0674No
98JPH2JPH212241-0.005-0.0673No
99FAM114A1FAM114A112331-0.006-0.0698No
100MMEMME12407-0.006-0.0717No
101HLA-DQB1HLA-DQB112616-0.006-0.0795No
102MYO1DMYO1D12831-0.007-0.0874No
103PTPRUPTPRU13450-0.009-0.1136No
104STAT6STAT613627-0.010-0.1190No
105MAP3K1MAP3K113827-0.010-0.1253No
106LAMB3LAMB313898-0.011-0.1255No
107TRAF1TRAF113990-0.011-0.1265No
108IL2RBIL2RB14060-0.011-0.1265No
109HMBOX1HMBOX114079-0.011-0.1241No
110JUPJUP14519-0.013-0.1408No
111EXPH5EXPH514654-0.013-0.1432No
112TNFRSF10DTNFRSF10D14712-0.014-0.1419No
113TUBB2ATUBB2A15383-0.016-0.1684No
114MAGEB2MAGEB215714-0.018-0.1787No
115RIPK4RIPK415918-0.019-0.1828Yes
116STEAP1STEAP115925-0.019-0.1777Yes
117MARK1MARK116034-0.019-0.1772Yes
118SPAG4SPAG416140-0.020-0.1764Yes
119SPINT1SPINT116232-0.020-0.1748Yes
120SERPINA1SERPINA116362-0.021-0.1749Yes
121CCND3CCND316368-0.021-0.1691Yes
122PTPRDPTPRD16374-0.021-0.1634Yes
123PHLPP1PHLPP116520-0.021-0.1640Yes
124NFKBIENFKBIE16753-0.023-0.1683Yes
125ID4ID416762-0.023-0.1621Yes
126G0S2G0S217260-0.025-0.1781Yes
127SLC9A7SLC9A717414-0.026-0.1778Yes
128S100A2S100A217551-0.027-0.1765Yes
129C9orf3C9orf317586-0.027-0.1704Yes
130BCL2A1BCL2A117594-0.027-0.1630Yes
131PDCD1LG2PDCD1LG217851-0.028-0.1667Yes
132TRAF3IP1TRAF3IP117858-0.028-0.1588Yes
133PLEK2PLEK218347-0.031-0.1725Yes
134PLEKHO1PLEKHO118411-0.032-0.1664Yes
135IL24IL2418723-0.034-0.1711Yes
136SALL2SALL218895-0.035-0.1691Yes
137SVILSVIL19033-0.036-0.1652Yes
138ICOSLGICOSLG19306-0.038-0.1669Yes
139TPMTTPMT19352-0.038-0.1580Yes
140KYNUKYNU19528-0.040-0.1547Yes
141IL1R1IL1R119546-0.040-0.1440Yes
142FMNL1FMNL119627-0.041-0.1361Yes
143SLC10A3SLC10A319679-0.041-0.1266Yes
144AGPAT2AGPAT219769-0.042-0.1187Yes
145CBR1CBR119808-0.042-0.1083Yes
146KRT7KRT719994-0.045-0.1040Yes
147CDS1CDS120163-0.046-0.0985Yes
148PNMA2PNMA220375-0.049-0.0940Yes
149NCANNCAN20556-0.053-0.0873Yes
150FOSL1FOSL120794-0.057-0.0818Yes
151DOCK2DOCK221196-0.070-0.0803Yes
152CXCL1CXCL121200-0.070-0.0602Yes
153IGFBP6IGFBP621454-0.091-0.0457Yes
154C1orf61C1orf6121592-0.1810.0002Yes
Table: GSEA details [plain text format]



Fig 2: VDR_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VDR_REGULON: Random ES distribution   
Gene set null distribution of ES for VDR_REGULON