Details for gene set SP100

Table: GSEA Results Summary

Dataset	shNF1_exprs.shNF1_phenotype.cls #shNF1_versus_shCtrl.shNF1_phenotype.cls #shNF1_versus_shCtrl_repos
Phenotype	shNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in class	shCtrl
GeneSet	SP100_REGULON
Enrichment Score (ES)	-0.4345241
Normalized Enrichment Score (NES)	-1.8772086
Nominal p-value	0.0
FDR q-value	5.756579E-4
FWER p-Value	0.002

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MDFIC	MDFIC	271	0.072	0.0058	No
2	LRP10	LRP10	479	0.062	0.0121	No
3	RETSAT	RETSAT	658	0.057	0.0184	No
4	MVP	MVP	711	0.056	0.0303	No
5	TBC1D8	TBC1D8	788	0.055	0.0407	No
6	NPTN	NPTN	878	0.053	0.0501	No
7	TCIRG1	TCIRG1	1021	0.050	0.0563	No
8	ELK3	ELK3	1072	0.049	0.0666	No
9	TAPBP	TAPBP	1578	0.043	0.0540	No
10	ITGBL1	ITGBL1	2047	0.038	0.0419	No
11	LRBA	LRBA	2261	0.036	0.0413	No
12	OSBPL3	OSBPL3	2755	0.033	0.0266	No
13	ICAM1	ICAM1	2950	0.031	0.0256	No
14	GBP1	GBP1	2993	0.031	0.0316	No
15	PML	PML	3150	0.030	0.0320	No
16	AMIGO2	AMIGO2	3194	0.030	0.0376	No
17	SMAGP	SMAGP	3414	0.028	0.0346	No
18	SOX11	SOX11	3515	0.028	0.0370	No
19	E2F5	E2F5	3627	0.027	0.0387	No
20	CLEC2B	CLEC2B	4145	0.024	0.0208	No
21	C1R	C1R	4214	0.024	0.0238	No
22	CAMKV	CAMKV	4489	0.023	0.0168	No
23	GATA6	GATA6	4962	0.020	0.0000	No
24	CASP4	CASP4	5106	0.020	-0.0016	No
25	RAB11FIP5	RAB11FIP5	5143	0.020	0.0017	No
26	HFE	HFE	5423	0.018	-0.0066	No
27	ASB13	ASB13	5884	0.016	-0.0238	No
28	SLFN12	SLFN12	5907	0.016	-0.0207	No
29	ARPC1B	ARPC1B	6192	0.015	-0.0301	No
30	RAB27A	RAB27A	6204	0.015	-0.0267	No
31	MICAL2	MICAL2	6513	0.014	-0.0376	No
32	CYLD	CYLD	6516	0.014	-0.0341	No
33	HCFC2	HCFC2	6633	0.013	-0.0361	No
34	FAS	FAS	6689	0.013	-0.0353	No
35	ERAP2	ERAP2	6928	0.012	-0.0433	No
36	APOL1	APOL1	7368	0.011	-0.0610	No
37	LPAR1	LPAR1	7876	0.009	-0.0824	No
38	SHC1	SHC1	8045	0.008	-0.0880	No
39	DDX60	DDX60	8367	0.007	-0.1011	No
40	PLP2	PLP2	8380	0.007	-0.0998	No
41	RALB	RALB	8436	0.007	-0.1005	No
42	DENND4A	DENND4A	8647	0.006	-0.1087	No
43	UTRN	UTRN	9466	0.004	-0.1458	No
44	TRIM38	TRIM38	9876	0.002	-0.1643	No
45	CHD7	CHD7	9974	0.002	-0.1683	No
46	IRF2	IRF2	9976	0.002	-0.1678	No
47	GNS	GNS	10291	0.001	-0.1821	No
48	ITGB5	ITGB5	10457	0.001	-0.1897	No
49	SLC16A6	SLC16A6	10468	0.001	-0.1900	No
50	TPBG	TPBG	10604	0.000	-0.1962	No
51	S100A11	S100A11	10703	-0.000	-0.2007	No
52	SP140L	SP140L	10912	-0.001	-0.2102	No
53	TRIM5	TRIM5	11347	-0.002	-0.2299	No
54	NUDT11	NUDT11	11624	-0.003	-0.2419	No
55	PARP12	PARP12	11918	-0.004	-0.2545	No
56	C1QTNF1	C1QTNF1	11992	-0.004	-0.2568	No
57	SECTM1	SECTM1	12070	-0.005	-0.2592	No
58	OAS2	OAS2	12174	-0.005	-0.2628	No
59	MMP14	MMP14	12245	-0.005	-0.2647	No
60	TAP1	TAP1	12289	-0.005	-0.2653	No
61	KBTBD11	KBTBD11	12489	-0.006	-0.2731	No
62	CASP8	CASP8	12893	-0.007	-0.2900	No
63	BACH2	BACH2	12964	-0.008	-0.2913	No
64	RUNX2	RUNX2	13175	-0.008	-0.2990	No
65	CASP1	CASP1	13302	-0.009	-0.3026	No
66	NLRP1	NLRP1	13867	-0.011	-0.3262	No
67	INTS9	INTS9	13879	-0.011	-0.3240	No
68	SCPEP1	SCPEP1	13899	-0.011	-0.3222	No
69	ERAP1	ERAP1	13923	-0.011	-0.3205	No
70	PARP3	PARP3	13963	-0.011	-0.3195	No
71	BIN1	BIN1	13979	-0.011	-0.3174	No
72	PROCR	PROCR	14056	-0.011	-0.3181	No
73	IFI16	IFI16	14371	-0.012	-0.3296	No
74	SDF4	SDF4	14481	-0.013	-0.3314	No
75	YPEL1	YPEL1	14618	-0.013	-0.3343	No
76	ANXA4	ANXA4	14631	-0.013	-0.3314	No
77	VRK1	VRK1	14755	-0.014	-0.3336	No
78	TRADD	TRADD	14833	-0.014	-0.3336	No
79	TLR3	TLR3	15001	-0.015	-0.3376	No
80	ALAD	ALAD	15243	-0.016	-0.3448	No
81	WIPI1	WIPI1	15356	-0.016	-0.3459	No
82	SEPHS1	SEPHS1	15849	-0.018	-0.3641	No
83	MR1	MR1	15904	-0.019	-0.3619	No
84	DDO	DDO	16097	-0.019	-0.3659	No
85	C1RL	C1RL	16390	-0.021	-0.3741	No
86	APOL3	APOL3	16408	-0.021	-0.3696	No
87	BTN3A3	BTN3A3	16601	-0.022	-0.3730	No
88	MGLL	MGLL	16941	-0.023	-0.3828	No
89	MFSD1	MFSD1	16964	-0.023	-0.3778	No
90	RNASEL	RNASEL	17483	-0.026	-0.3952	No
91	B2M	B2M	17865	-0.028	-0.4057	No
92	PSMB8	PSMB8	18363	-0.031	-0.4209	No
93	CBX5	CBX5	18368	-0.031	-0.4130	No
94	LNPEP	LNPEP	18551	-0.032	-0.4132	No
95	TRIM21	TRIM21	18682	-0.033	-0.4108	No
96	SALL2	SALL2	18895	-0.035	-0.4118	No
97	HLA-B	HLA-B	18926	-0.035	-0.4042	No
98	GSDMD	GSDMD	19445	-0.039	-0.4184	No
99	FLT3LG	FLT3LG	19792	-0.042	-0.4238	Yes
100	CUEDC2	CUEDC2	19824	-0.042	-0.4144	Yes
101	APOBEC3G	APOBEC3G	19920	-0.044	-0.4076	Yes
102	MX1	MX1	19984	-0.044	-0.3992	Yes
103	OSTF1	OSTF1	20018	-0.045	-0.3893	Yes
104	DDX58	DDX58	20077	-0.045	-0.3804	Yes
105	IFIT3	IFIT3	20082	-0.045	-0.3690	Yes
106	SAMD9	SAMD9	20134	-0.046	-0.3596	Yes
107	HERC5	HERC5	20185	-0.047	-0.3501	Yes
108	MTSS1	MTSS1	20289	-0.048	-0.3426	Yes
109	PHF11	PHF11	20428	-0.050	-0.3362	Yes
110	HLA-F	HLA-F	20653	-0.054	-0.3327	Yes
111	HERC6	HERC6	20663	-0.055	-0.3192	Yes
112	IRF1	IRF1	20690	-0.055	-0.3063	Yes
113	PPIC	PPIC	20717	-0.056	-0.2933	Yes
114	SP110	SP110	20846	-0.058	-0.2844	Yes
115	APOM	APOM	20908	-0.060	-0.2719	Yes
116	TMEM140	TMEM140	20922	-0.060	-0.2571	Yes
117	HLA-E	HLA-E	20930	-0.061	-0.2419	Yes
118	RTP4	RTP4	21020	-0.063	-0.2299	Yes
119	BLVRB	BLVRB	21104	-0.066	-0.2168	Yes
120	HLA-C	HLA-C	21127	-0.067	-0.2007	Yes
121	DHX58	DHX58	21153	-0.068	-0.1844	Yes
122	TAPBPL	TAPBPL	21272	-0.074	-0.1710	Yes
123	NMI	NMI	21290	-0.075	-0.1527	Yes
124	TNFRSF14	TNFRSF14	21312	-0.076	-0.1343	Yes
125	STAT1	STAT1	21320	-0.076	-0.1152	Yes
126	IFI35	IFI35	21374	-0.081	-0.0970	Yes
127	XAF1	XAF1	21402	-0.084	-0.0769	Yes
128	PSMB9	PSMB9	21406	-0.084	-0.0555	Yes
129	C19orf66	C19orf66	21434	-0.087	-0.0345	Yes
130	BST2	BST2	21587	-0.164	0.0004	Yes