Details for gene set SCHMITT_TNF

Table: GSEA Results Summary

Dataset	shNF1_exprs.shNF1_phenotype.cls #shNF1_versus_shCtrl.shNF1_phenotype.cls #shNF1_versus_shCtrl_repos
Phenotype	shNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in class	shCtrl
GeneSet	SCHMITT_TNF_2020
Enrichment Score (ES)	-0.21984534
Normalized Enrichment Score (NES)	-1.0642393
Nominal p-value	0.273021
FDR q-value	0.4127448
FWER p-Value	0.999

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	AHNAK2	AHNAK2	25	0.114	0.0127	No
2	RDH10	RDH10	82	0.093	0.0213	No
3	PLAU	PLAU	94	0.090	0.0318	No
4	CD44	CD44	141	0.084	0.0398	No
5	RBM3	RBM3	172	0.080	0.0482	No
6	ADAMTS1	ADAMTS1	349	0.068	0.0482	No
7	RNF145	RNF145	387	0.066	0.0545	No
8	NAMPT	NAMPT	426	0.065	0.0606	No
9	TNC	TNC	488	0.062	0.0652	No
10	OSMR	OSMR	580	0.059	0.0682	No
11	ELL2	ELL2	633	0.058	0.0728	No
12	SGK1	SGK1	650	0.057	0.0790	No
13	ITGAV	ITGAV	676	0.057	0.0847	No
14	PMP22	PMP22	706	0.056	0.0902	No
15	SH2B3	SH2B3	724	0.056	0.0962	No
16	SERPINE1	SERPINE1	725	0.056	0.1030	No
17	NFE2L3	NFE2L3	787	0.055	0.1067	No
18	EGR2	EGR2	870	0.053	0.1094	No
19	SNX10	SNX10	963	0.051	0.1113	No
20	OSBPL5	OSBPL5	1007	0.050	0.1154	No
21	NCOA7	NCOA7	1043	0.050	0.1198	No
22	RPGR	RPGR	1089	0.049	0.1237	No
23	FAM129A	FAM129A	1139	0.048	0.1272	No
24	WWTR1	WWTR1	1155	0.048	0.1324	No
25	SYT12	SYT12	1190	0.047	0.1365	No
26	ARHGEF16	ARHGEF16	1218	0.047	0.1410	No
27	LRRC4B	LRRC4B	1223	0.047	0.1465	No
28	EFTUD2	EFTUD2	1256	0.047	0.1507	No
29	ADAMTS9	ADAMTS9	1330	0.046	0.1528	No
30	ARHGEF4	ARHGEF4	1335	0.045	0.1581	No
31	GRWD1	GRWD1	1444	0.044	0.1584	No
32	MAP3K11	MAP3K11	1466	0.044	0.1627	No
33	SLC2A3	SLC2A3	1536	0.043	0.1647	No
34	EMP1	EMP1	1560	0.043	0.1689	No
35	TAPBP	TAPBP	1578	0.043	0.1733	No
36	PLAT	PLAT	1636	0.042	0.1757	No
37	NRCAM	NRCAM	1689	0.042	0.1783	No
38	BIRC2	BIRC2	1696	0.041	0.1831	No
39	DUSP5	DUSP5	1702	0.041	0.1879	No
40	ZNF528	ZNF528	1739	0.041	0.1912	No
41	PLCD3	PLCD3	2053	0.038	0.1811	No
42	PRICKLE1	PRICKLE1	2075	0.038	0.1847	No
43	PTPRE	PTPRE	2197	0.037	0.1835	No
44	ADAM19	ADAM19	2199	0.037	0.1880	No
45	ZNF701	ZNF701	2293	0.036	0.1880	No
46	COL9A1	COL9A1	2387	0.035	0.1879	No
47	SPP1	SPP1	2411	0.035	0.1911	No
48	DUSP6	DUSP6	2450	0.035	0.1936	No
49	ARL6IP5	ARL6IP5	2561	0.034	0.1926	No
50	NR4A3	NR4A3	2589	0.034	0.1954	No
51	IGFBP3	IGFBP3	2656	0.033	0.1963	No
52	CABLES1	CABLES1	2708	0.033	0.1980	No
53	MPZ	MPZ	2812	0.032	0.1970	No
54	SLC16A3	SLC16A3	2914	0.032	0.1961	No
55	ICAM1	ICAM1	2950	0.031	0.1983	No
56	KLF10	KLF10	3092	0.030	0.1954	No
57	AGT	AGT	3200	0.030	0.1940	No
58	ARRDC4	ARRDC4	3209	0.030	0.1972	No
59	KIAA0040	KIAA0040	3344	0.029	0.1944	No
60	MGAT3	MGAT3	3486	0.028	0.1912	No
61	KLHL5	KLHL5	3501	0.028	0.1939	No
62	ABR	ABR	3629	0.027	0.1912	No
63	ZIK1	ZIK1	3651	0.027	0.1935	No
64	ZSWIM4	ZSWIM4	4201	0.024	0.1706	No
65	EMILIN1	EMILIN1	4248	0.024	0.1714	No
66	GCLM	GCLM	4379	0.023	0.1681	No
67	SEMA4B	SEMA4B	4397	0.023	0.1701	No
68	RIPK1	RIPK1	4403	0.023	0.1727	No
69	NBL1	NBL1	4431	0.023	0.1742	No
70	ETNK2	ETNK2	4503	0.023	0.1736	No
71	TRIM8	TRIM8	4618	0.022	0.1709	No
72	CHI3L1	CHI3L1	4752	0.021	0.1673	No
73	TAGLN2	TAGLN2	4844	0.021	0.1655	No
74	LRP2	LRP2	5128	0.020	0.1546	No
75	FGF2	FGF2	5289	0.019	0.1494	No
76	ANXA1	ANXA1	5293	0.019	0.1516	No
77	FADS3	FADS3	5335	0.019	0.1519	No
78	PTX3	PTX3	5379	0.018	0.1522	No
79	L1CAM	L1CAM	5566	0.018	0.1456	No
80	DRAM1	DRAM1	5593	0.018	0.1465	No
81	GTSF1	GTSF1	5606	0.017	0.1481	No
82	RAB35	RAB35	5868	0.016	0.1378	No
83	TMEM158	TMEM158	5946	0.016	0.1362	No
84	SFRP1	SFRP1	5972	0.016	0.1369	No
85	UGCG	UGCG	6131	0.015	0.1314	No
86	MGAT4B	MGAT4B	6161	0.015	0.1319	No
87	PERP	PERP	6265	0.015	0.1288	No
88	CDH4	CDH4	6379	0.014	0.1252	No
89	LPGAT1	LPGAT1	6405	0.014	0.1258	No
90	MAOB	MAOB	6447	0.014	0.1256	No
91	CYLD	CYLD	6516	0.014	0.1241	No
92	RGS16	RGS16	6547	0.014	0.1243	No
93	MYO5B	MYO5B	6571	0.014	0.1249	No
94	THY1	THY1	6652	0.013	0.1228	No
95	PCDH1	PCDH1	6707	0.013	0.1218	No
96	ADAMTS4	ADAMTS4	6977	0.012	0.1106	No
97	SYNGR3	SYNGR3	7095	0.012	0.1066	No
98	GFRA1	GFRA1	7266	0.011	0.0999	No
99	HMOX1	HMOX1	7308	0.011	0.0993	No
100	RELL1	RELL1	7311	0.011	0.1005	No
101	KCNN4	KCNN4	7369	0.011	0.0992	No
102	CITED4	CITED4	7421	0.011	0.0981	No
103	LIF	LIF	7552	0.010	0.0932	No
104	SOCS3	SOCS3	7565	0.010	0.0938	No
105	PGM2L1	PGM2L1	7861	0.009	0.0811	No
106	ZDHHC14	ZDHHC14	7892	0.009	0.0807	No
107	ZNF611	ZNF611	7906	0.009	0.0812	No
108	IER2	IER2	7947	0.009	0.0804	No
109	KLF5	KLF5	7958	0.009	0.0810	No
110	ADAMTS14	ADAMTS14	7964	0.009	0.0818	No
111	IL1RAP	IL1RAP	8040	0.008	0.0793	No
112	CSF1	CSF1	8101	0.008	0.0775	No
113	NPNT	NPNT	8220	0.008	0.0729	No
114	FOSL2	FOSL2	8254	0.008	0.0723	No
115	IL4I1	IL4I1	8341	0.007	0.0691	No
116	NFKB2	NFKB2	8342	0.007	0.0700	No
117	FZD5	FZD5	8463	0.007	0.0653	No
118	NUDT4	NUDT4	8590	0.007	0.0601	No
119	IER3	IER3	8602	0.007	0.0604	No
120	SMOC2	SMOC2	8614	0.007	0.0607	No
121	IRF3	IRF3	8619	0.007	0.0613	No
122	C1orf226	C1orf226	8697	0.006	0.0584	No
123	FZD8	FZD8	8737	0.006	0.0574	No
124	IL27RA	IL27RA	8743	0.006	0.0579	No
125	SPSB1	SPSB1	8857	0.006	0.0533	No
126	BMP2	BMP2	8885	0.006	0.0527	No
127	ZNF667	ZNF667	9136	0.005	0.0415	No
128	WARS	WARS	9459	0.004	0.0269	No
129	TAF13	TAF13	9465	0.004	0.0271	No
130	CDKN2B	CDKN2B	9502	0.004	0.0258	No
131	ZNF347	ZNF347	9527	0.004	0.0252	No
132	ZNF468	ZNF468	9567	0.003	0.0237	No
133	FAM43A	FAM43A	9601	0.003	0.0226	No
134	LAPTM5	LAPTM5	9604	0.003	0.0229	No
135	CAMK2D	CAMK2D	9629	0.003	0.0222	No
136	IL6ST	IL6ST	9746	0.003	0.0170	No
137	ZBED1	ZBED1	9842	0.002	0.0129	No
138	BCL3	BCL3	9852	0.002	0.0128	No
139	ENPP2	ENPP2	9984	0.002	0.0069	No
140	HAS2	HAS2	9986	0.002	0.0071	No
141	STOM	STOM	10182	0.001	-0.0019	No
142	BMP5	BMP5	10348	0.001	-0.0096	No
143	RASEF	RASEF	10445	0.001	-0.0140	No
144	SGPP2	SGPP2	10471	0.001	-0.0151	No
145	CTSS	CTSS	10531	0.000	-0.0178	No
146	BCL6	BCL6	10628	0.000	-0.0223	No
147	TNFRSF12A	TNFRSF12A	10650	0.000	-0.0233	No
148	PNKD	PNKD	10694	-0.000	-0.0253	No
149	CNTNAP1	CNTNAP1	10758	-0.000	-0.0282	No
150	HIVEP1	HIVEP1	10907	-0.001	-0.0351	No
151	DPP4	DPP4	10921	-0.001	-0.0356	No
152	C10orf90	C10orf90	11075	-0.001	-0.0426	No
153	LGALS1	LGALS1	11128	-0.001	-0.0449	No
154	S100A10	S100A10	11216	-0.002	-0.0487	No
155	IRAK2	IRAK2	11333	-0.002	-0.0539	No
156	C1orf198	C1orf198	11388	-0.002	-0.0562	No
157	SPRED3	SPRED3	11502	-0.003	-0.0611	No
158	LHX9	LHX9	11566	-0.003	-0.0637	No
159	FJX1	FJX1	11575	-0.003	-0.0638	No
160	ASPHD1	ASPHD1	11595	-0.003	-0.0643	No
161	SQSTM1	SQSTM1	11598	-0.003	-0.0640	No
162	DACT1	DACT1	11619	-0.003	-0.0646	No
163	CA8	CA8	11620	-0.003	-0.0642	No
164	GABRA5	GABRA5	11667	-0.003	-0.0660	No
165	CDC42EP5	CDC42EP5	11669	-0.003	-0.0656	No
166	PDGFA	PDGFA	11928	-0.004	-0.0772	No
167	ZNF813	ZNF813	11939	-0.004	-0.0772	No
168	PIK3CD	PIK3CD	11950	-0.004	-0.0772	No
169	STAT3	STAT3	12000	-0.004	-0.0789	No
170	ZNF329	ZNF329	12024	-0.004	-0.0795	No
171	DOC2B	DOC2B	12058	-0.005	-0.0805	No
172	SORBS1	SORBS1	12199	-0.005	-0.0864	No
173	VWA1	VWA1	12201	-0.005	-0.0858	No
174	ALPK1	ALPK1	12247	-0.005	-0.0873	No
175	CLIC2	CLIC2	12353	-0.006	-0.0916	No
176	SEMA3B	SEMA3B	12400	-0.006	-0.0930	No
177	RHPN2	RHPN2	12485	-0.006	-0.0962	No
178	ACSL6	ACSL6	12624	-0.006	-0.1019	No
179	NRG1	NRG1	12821	-0.007	-0.1103	No
180	C4A	C4A	12892	-0.007	-0.1127	No
181	LARP6	LARP6	12926	-0.007	-0.1133	No
182	PDGFRL	PDGFRL	13079	-0.008	-0.1195	No
183	ZNF28	ZNF28	13167	-0.008	-0.1226	No
184	APBA1	APBA1	13243	-0.008	-0.1251	No
185	ASB9	ASB9	13256	-0.008	-0.1246	No
186	NR4A1	NR4A1	13330	-0.009	-0.1270	No
187	TNFRSF9	TNFRSF9	13379	-0.009	-0.1281	No
188	CD63	CD63	13471	-0.009	-0.1313	No
189	GRB10	GRB10	13536	-0.009	-0.1332	No
190	RGS3	RGS3	13557	-0.009	-0.1329	No
191	MICALL2	MICALL2	13569	-0.010	-0.1323	No
192	PGBD5	PGBD5	13582	-0.010	-0.1317	No
193	PRKAR1B	PRKAR1B	13742	-0.010	-0.1379	No
194	EMILIN2	EMILIN2	13747	-0.010	-0.1369	No
195	VAX1	VAX1	13903	-0.011	-0.1429	No
196	ERAP1	ERAP1	13923	-0.011	-0.1424	No
197	TRAF1	TRAF1	13990	-0.011	-0.1442	No
198	SERPINA3	SERPINA3	14162	-0.012	-0.1508	No
199	PXDN	PXDN	14300	-0.012	-0.1558	No
200	TMEM151B	TMEM151B	14400	-0.012	-0.1589	No
201	STAP2	STAP2	14427	-0.013	-0.1586	No
202	ZNF229	ZNF229	14428	-0.013	-0.1571	No
203	PTP4A3	PTP4A3	14475	-0.013	-0.1577	No
204	ZNF267	ZNF267	14587	-0.013	-0.1613	No
205	CDKN1A	CDKN1A	14918	-0.014	-0.1750	No
206	SDC4	SDC4	14948	-0.015	-0.1746	No
207	LOXL2	LOXL2	14962	-0.015	-0.1734	No
208	AHR	AHR	15028	-0.015	-0.1747	No
209	TNIP2	TNIP2	15269	-0.016	-0.1840	No
210	SLC16A9	SLC16A9	15307	-0.016	-0.1838	No
211	JUNB	JUNB	15319	-0.016	-0.1824	No
212	BACE2	BACE2	15352	-0.016	-0.1819	No
213	GABRB3	GABRB3	15373	-0.016	-0.1809	No
214	NDUFB8	NDUFB8	15387	-0.016	-0.1795	No
215	EGFLAM	EGFLAM	15424	-0.017	-0.1792	No
216	PSMD5	PSMD5	15705	-0.018	-0.1902	No
217	SYNPO	SYNPO	15750	-0.018	-0.1900	No
218	PRR16	PRR16	15808	-0.018	-0.1905	No
219	RAB31	RAB31	15883	-0.018	-0.1917	No
220	ROBO1	ROBO1	15917	-0.019	-0.1910	No
221	ALPL	ALPL	15927	-0.019	-0.1892	No
222	NFKBIZ	NFKBIZ	15950	-0.019	-0.1879	No
223	TSC22D4	TSC22D4	15969	-0.019	-0.1865	No
224	CYP1A1	CYP1A1	15993	-0.019	-0.1852	No
225	TIMP1	TIMP1	16033	-0.019	-0.1847	No
226	TMEM173	TMEM173	16087	-0.019	-0.1849	No
227	ORAI1	ORAI1	16179	-0.020	-0.1867	No
228	CDKAL1	CDKAL1	16212	-0.020	-0.1858	No
229	EMP3	EMP3	16399	-0.021	-0.1920	No
230	IFNGR2	IFNGR2	16407	-0.021	-0.1898	No
231	TGFB1	TGFB1	16486	-0.021	-0.1909	No
232	EBI3	EBI3	16613	-0.022	-0.1941	No
233	CARS	CARS	16647	-0.022	-0.1930	No
234	NUAK2	NUAK2	16714	-0.022	-0.1934	No
235	NAB2	NAB2	16741	-0.022	-0.1918	No
236	NFKBIE	NFKBIE	16753	-0.023	-0.1896	No
237	ATCAY	ATCAY	16784	-0.023	-0.1883	No
238	ZNF766	ZNF766	17043	-0.024	-0.1975	No
239	TIFA	TIFA	17139	-0.024	-0.1990	No
240	NFKB1	NFKB1	17156	-0.024	-0.1968	No
241	ETV6	ETV6	17172	-0.024	-0.1945	No
242	F3	F3	17464	-0.026	-0.2050	No
243	ZFP36	ZFP36	17472	-0.026	-0.2022	No
244	VDR	VDR	17575	-0.027	-0.2037	No
245	TRPM8	TRPM8	17614	-0.027	-0.2022	No
246	ARNTL2	ARNTL2	17840	-0.028	-0.2094	No
247	B2M	B2M	17865	-0.028	-0.2070	No
248	PODXL	PODXL	18139	-0.030	-0.2162	Yes
249	CAPN5	CAPN5	18149	-0.030	-0.2130	Yes
250	TNFAIP3	TNFAIP3	18220	-0.030	-0.2125	Yes
251	CLDN4	CLDN4	18245	-0.031	-0.2099	Yes
252	IFNGR1	IFNGR1	18286	-0.031	-0.2081	Yes
253	APOL6	APOL6	18357	-0.031	-0.2075	Yes
254	TNFRSF1A	TNFRSF1A	18376	-0.031	-0.2046	Yes
255	KREMEN2	KREMEN2	18433	-0.032	-0.2033	Yes
256	RELB	RELB	18625	-0.033	-0.2083	Yes
257	KLHL6	KLHL6	18640	-0.033	-0.2049	Yes
258	HLA-B	HLA-B	18926	-0.035	-0.2141	Yes
259	LIMD2	LIMD2	18969	-0.035	-0.2117	Yes
260	PEPD	PEPD	19062	-0.036	-0.2117	Yes
261	TBC1D10A	TBC1D10A	19159	-0.037	-0.2117	Yes
262	SERTAD1	SERTAD1	19291	-0.038	-0.2133	Yes
263	DTX3L	DTX3L	19343	-0.038	-0.2110	Yes
264	IFIH1	IFIH1	19379	-0.039	-0.2080	Yes
265	ANO9	ANO9	19420	-0.039	-0.2052	Yes
266	SPARCL1	SPARCL1	19426	-0.039	-0.2007	Yes
267	IL32	IL32	19484	-0.039	-0.1986	Yes
268	GAP43	GAP43	19602	-0.040	-0.1992	Yes
269	PLEKHA4	PLEKHA4	19653	-0.041	-0.1965	Yes
270	NTN1	NTN1	19759	-0.042	-0.1964	Yes
271	CRABP2	CRABP2	19841	-0.043	-0.1950	Yes
272	LIFR	LIFR	19899	-0.043	-0.1924	Yes
273	FAM131B	FAM131B	19958	-0.044	-0.1898	Yes
274	CITED1	CITED1	20122	-0.046	-0.1918	Yes
275	SOD2	SOD2	20301	-0.048	-0.1943	Yes
276	RRAS	RRAS	20323	-0.049	-0.1894	Yes
277	FAM174B	FAM174B	20370	-0.049	-0.1856	Yes
278	OPTN	OPTN	20412	-0.050	-0.1814	Yes
279	CREB3	CREB3	20436	-0.050	-0.1764	Yes
280	CSRP2	CSRP2	20480	-0.051	-0.1722	Yes
281	WIPF3	WIPF3	20571	-0.053	-0.1700	Yes
282	RAB13	RAB13	20576	-0.053	-0.1637	Yes
283	A2M	A2M	20660	-0.055	-0.1610	Yes
284	PARP9	PARP9	20685	-0.055	-0.1554	Yes
285	IRF1	IRF1	20690	-0.055	-0.1489	Yes
286	OSCP1	OSCP1	20719	-0.056	-0.1434	Yes
287	RNF19A	RNF19A	20805	-0.058	-0.1404	Yes
288	CD83	CD83	20841	-0.058	-0.1350	Yes
289	CXCL10	CXCL10	20903	-0.060	-0.1306	Yes
290	HLA-E	HLA-E	20930	-0.061	-0.1244	Yes
291	INSR	INSR	20961	-0.062	-0.1183	Yes
292	VGF	VGF	21040	-0.064	-0.1142	Yes
293	PLEKHF1	PLEKHF1	21123	-0.067	-0.1099	Yes
294	BATF3	BATF3	21207	-0.070	-0.1052	Yes
295	PLLP	PLLP	21296	-0.075	-0.1002	Yes
296	CYP4V2	CYP4V2	21304	-0.075	-0.0914	Yes
297	LRRN3	LRRN3	21309	-0.076	-0.0824	Yes
298	CEBPB	CEBPB	21428	-0.086	-0.0774	Yes
299	ISG20	ISG20	21453	-0.091	-0.0674	Yes
300	MITD1	MITD1	21492	-0.096	-0.0575	Yes
301	NFKBIA	NFKBIA	21524	-0.105	-0.0462	Yes
302	PLA2G4C	PLA2G4C	21551	-0.117	-0.0332	Yes
303	IFITM1	IFITM1	21556	-0.120	-0.0189	Yes
304	MATN2	MATN2	21589	-0.170	0.0003	Yes