Details for gene set SCHMITT_HMG

Table: GSEA Results Summary

Dataset	shNF1_exprs.shNF1_phenotype.cls #shNF1_versus_shCtrl.shNF1_phenotype.cls #shNF1_versus_shCtrl_repos
Phenotype	shNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in class	shCtrl
GeneSet	SCHMITT_HMG_2020
Enrichment Score (ES)	-0.24968427
Normalized Enrichment Score (NES)	-1.1926215
Nominal p-value	0.09256198
FDR q-value	0.2458025
FWER p-Value	0.939

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BCYRN1	BCYRN1	6	0.135	0.0160	No
2	MAN2A1	MAN2A1	12	0.125	0.0308	No
3	AHNAK2	AHNAK2	25	0.114	0.0439	No
4	COL6A1	COL6A1	29	0.107	0.0566	No
5	RDH10	RDH10	82	0.093	0.0653	No
6	COL6A2	COL6A2	92	0.091	0.0758	No
7	CD44	CD44	141	0.084	0.0836	No
8	PTCHD1	PTCHD1	173	0.080	0.0917	No
9	GOLT1B	GOLT1B	293	0.071	0.0946	No
10	PDGFRB	PDGFRB	370	0.067	0.0991	No
11	NAMPT	NAMPT	426	0.065	0.1043	No
12	TNC	TNC	488	0.062	0.1089	No
13	OSMR	OSMR	580	0.059	0.1117	No
14	SGK1	SGK1	650	0.057	0.1154	No
15	PMP22	PMP22	706	0.056	0.1196	No
16	MVP	MVP	711	0.056	0.1261	No
17	SERPINE1	SERPINE1	725	0.056	0.1322	No
18	LDLR	LDLR	923	0.052	0.1292	No
19	SNX10	SNX10	963	0.051	0.1336	No
20	ABHD4	ABHD4	1124	0.049	0.1319	No
21	PMM2	PMM2	1142	0.048	0.1369	No
22	RUNX1T1	RUNX1T1	1160	0.048	0.1419	No
23	SPTY2D1	SPTY2D1	1243	0.047	0.1436	No
24	GRIK1	GRIK1	1270	0.046	0.1480	No
25	HMGCS1	HMGCS1	1450	0.044	0.1449	No
26	PPP2R5A	PPP2R5A	1498	0.043	0.1479	No
27	SLC2A3	SLC2A3	1536	0.043	0.1513	No
28	EMP1	EMP1	1560	0.043	0.1554	No
29	CLU	CLU	1635	0.042	0.1570	No
30	NRCAM	NRCAM	1689	0.042	0.1595	No
31	GLIS3	GLIS3	1691	0.041	0.1644	No
32	DUSP5	DUSP5	1702	0.041	0.1689	No
33	IDI1	IDI1	1936	0.039	0.1627	No
34	LIPG	LIPG	1986	0.039	0.1651	No
35	GPR20	GPR20	2062	0.038	0.1661	No
36	FGD4	FGD4	2095	0.038	0.1692	No
37	NEDD9	NEDD9	2245	0.036	0.1665	No
38	ZBTB41	ZBTB41	2533	0.034	0.1572	No
39	NR4A3	NR4A3	2589	0.034	0.1587	No
40	EPHA5	EPHA5	2756	0.033	0.1548	No
41	HSD3B7	HSD3B7	2762	0.033	0.1585	No
42	CHN2	CHN2	2905	0.032	0.1556	No
43	ICAM1	ICAM1	2950	0.031	0.1573	No
44	ATF3	ATF3	2995	0.031	0.1590	No
45	SYCP2	SYCP2	3089	0.030	0.1583	No
46	PTGES	PTGES	3126	0.030	0.1602	No
47	GOLGB1	GOLGB1	3127	0.030	0.1639	No
48	AGT	AGT	3200	0.030	0.1641	No
49	SLC30A5	SLC30A5	3286	0.029	0.1636	No
50	KIAA0040	KIAA0040	3344	0.029	0.1644	No
51	LONRF1	LONRF1	3350	0.029	0.1676	No
52	LGMN	LGMN	3450	0.028	0.1663	No
53	TSC22D3	TSC22D3	3537	0.028	0.1656	No
54	VASH2	VASH2	3549	0.028	0.1684	No
55	BCAM	BCAM	3806	0.026	0.1595	No
56	YOD1	YOD1	3836	0.026	0.1613	No
57	SLC26A2	SLC26A2	3842	0.026	0.1642	No
58	RAB5A	RAB5A	4090	0.025	0.1555	No
59	MKNK1	MKNK1	4120	0.024	0.1571	No
60	UFM1	UFM1	4157	0.024	0.1583	No
61	ATG9B	ATG9B	4218	0.024	0.1584	No
62	SEMA4B	SEMA4B	4397	0.023	0.1528	No
63	PROS1	PROS1	4512	0.023	0.1502	No
64	CLIP2	CLIP2	4695	0.022	0.1442	No
65	ACBD3	ACBD3	4741	0.021	0.1447	No
66	TTC39B	TTC39B	4747	0.021	0.1470	No
67	CHI3L1	CHI3L1	4752	0.021	0.1494	No
68	PDP2	PDP2	4828	0.021	0.1484	No
69	TMEM231	TMEM231	4837	0.021	0.1506	No
70	TAGLN2	TAGLN2	4844	0.021	0.1528	No
71	SLC16A4	SLC16A4	4867	0.021	0.1543	No
72	PKIG	PKIG	5028	0.020	0.1492	No
73	RPL37A	RPL37A	5043	0.020	0.1510	No
74	CRELD1	CRELD1	5048	0.020	0.1532	No
75	C1orf162	C1orf162	5313	0.019	0.1431	No
76	DCAF4L1	DCAF4L1	5394	0.018	0.1415	No
77	GLRX	GLRX	5615	0.017	0.1333	No
78	MALT1	MALT1	5677	0.017	0.1325	No
79	EIF2AK3	EIF2AK3	5823	0.017	0.1277	No
80	GBP2	GBP2	5962	0.016	0.1232	No
81	ZFP28	ZFP28	5974	0.016	0.1246	No
82	JAG2	JAG2	6191	0.015	0.1162	No
83	THBS2	THBS2	6206	0.015	0.1174	No
84	ANXA11	ANXA11	6270	0.015	0.1162	No
85	MOSPD1	MOSPD1	6292	0.015	0.1170	No
86	GDA	GDA	6392	0.014	0.1141	No
87	VMAC	VMAC	6394	0.014	0.1157	No
88	RGS16	RGS16	6547	0.014	0.1102	No
89	MYO5B	MYO5B	6571	0.014	0.1108	No
90	FSTL5	FSTL5	6693	0.013	0.1067	No
91	C1S	C1S	6766	0.013	0.1049	No
92	KCNK10	KCNK10	6833	0.013	0.1033	No
93	ACSS2	ACSS2	6878	0.012	0.1027	No
94	PFKFB2	PFKFB2	6884	0.012	0.1040	No
95	GPR107	GPR107	6891	0.012	0.1052	No
96	SRPX	SRPX	6897	0.012	0.1065	No
97	TMCC3	TMCC3	7155	0.011	0.0958	No
98	GJA3	GJA3	7264	0.011	0.0920	No
99	PORCN	PORCN	7296	0.011	0.0919	No
100	EEPD1	EEPD1	7411	0.011	0.0878	No
101	DCDC2	DCDC2	7487	0.010	0.0856	No
102	SOCS3	SOCS3	7565	0.010	0.0831	No
103	PJA2	PJA2	7649	0.010	0.0804	No
104	IL21R	IL21R	7705	0.010	0.0790	No
105	SPTB	SPTB	7785	0.009	0.0764	No
106	SH3BP5	SH3BP5	7805	0.009	0.0766	No
107	PGM2L1	PGM2L1	7861	0.009	0.0751	No
108	IL13RA1	IL13RA1	8033	0.008	0.0681	No
109	CSF1	CSF1	8101	0.008	0.0660	No
110	KLF6	KLF6	8318	0.008	0.0567	No
111	DNHD1	DNHD1	8354	0.007	0.0560	No
112	YPEL2	YPEL2	8392	0.007	0.0551	No
113	FZD5	FZD5	8463	0.007	0.0527	No
114	MERTK	MERTK	8524	0.007	0.0507	No
115	TMEM87B	TMEM87B	8588	0.007	0.0485	No
116	TAF1D	TAF1D	8715	0.006	0.0434	No
117	MTUS1	MTUS1	8750	0.006	0.0425	No
118	C9orf72	C9orf72	8849	0.006	0.0386	No
119	CIR1	CIR1	9110	0.005	0.0270	No
120	INSIG1	INSIG1	9121	0.005	0.0271	No
121	TMEM50B	TMEM50B	9225	0.004	0.0228	No
122	MAFF	MAFF	9596	0.003	0.0059	No
123	LAPTM5	LAPTM5	9604	0.003	0.0059	No
124	CAMK2D	CAMK2D	9629	0.003	0.0052	No
125	CCNG1	CCNG1	9675	0.003	0.0035	No
126	ZBTB46	ZBTB46	9705	0.003	0.0025	No
127	DGKI	DGKI	10108	0.002	-0.0162	No
128	APOL2	APOL2	10270	0.001	-0.0236	No
129	BMP5	BMP5	10348	0.001	-0.0271	No
130	GOLGA4	GOLGA4	10466	0.001	-0.0325	No
131	LIN7A	LIN7A	10583	0.000	-0.0379	No
132	BCL6	BCL6	10628	0.000	-0.0400	No
133	PDXDC1	PDXDC1	10731	-0.000	-0.0447	No
134	SEC14L1	SEC14L1	10735	-0.000	-0.0449	No
135	DDR1	DDR1	10864	-0.001	-0.0508	No
136	LYST	LYST	10914	-0.001	-0.0530	No
137	CBX7	CBX7	10970	-0.001	-0.0554	No
138	GOLGA3	GOLGA3	11015	-0.001	-0.0574	No
139	HDAC9	HDAC9	11049	-0.001	-0.0588	No
140	COL14A1	COL14A1	11066	-0.001	-0.0594	No
141	MAP3K6	MAP3K6	11111	-0.001	-0.0612	No
142	S100A10	S100A10	11216	-0.002	-0.0659	No
143	EDEM3	EDEM3	11335	-0.002	-0.0712	No
144	LHX9	LHX9	11566	-0.003	-0.0816	No
145	AHNAK	AHNAK	11869	-0.004	-0.0953	No
146	KCNA4	KCNA4	12101	-0.005	-0.1056	No
147	ITGA11	ITGA11	12219	-0.005	-0.1105	No
148	ALPK1	ALPK1	12247	-0.005	-0.1111	No
149	ARRDC3	ARRDC3	12290	-0.005	-0.1124	No
150	FAM114A1	FAM114A1	12331	-0.006	-0.1136	No
151	CLIC2	CLIC2	12353	-0.006	-0.1139	No
152	FMN2	FMN2	12401	-0.006	-0.1155	No
153	ACSL6	ACSL6	12624	-0.006	-0.1251	No
154	RAB3B	RAB3B	12649	-0.006	-0.1254	No
155	ARID5A	ARID5A	12660	-0.007	-0.1251	No
156	RPE65	RPE65	12670	-0.007	-0.1248	No
157	C4A	C4A	12892	-0.007	-0.1342	No
158	PPM1K	PPM1K	12992	-0.008	-0.1380	No
159	FBXO32	FBXO32	13025	-0.008	-0.1385	No
160	TCP11L2	TCP11L2	13119	-0.008	-0.1419	No
161	SPARC	SPARC	13228	-0.008	-0.1460	No
162	RGS3	RGS3	13557	-0.009	-0.1602	No
163	USP51	USP51	13624	-0.010	-0.1622	No
164	PIKFYVE	PIKFYVE	13752	-0.010	-0.1669	No
165	IL6R	IL6R	13823	-0.010	-0.1689	No
166	NDRG2	NDRG2	13872	-0.011	-0.1699	No
167	ARMCX1	ARMCX1	13972	-0.011	-0.1732	No
168	TRAF1	TRAF1	13990	-0.011	-0.1727	No
169	PDE4DIP	PDE4DIP	14030	-0.011	-0.1732	No
170	SERPINA3	SERPINA3	14162	-0.012	-0.1779	No
171	CRTAP	CRTAP	14254	-0.012	-0.1808	No
172	PTP4A3	PTP4A3	14475	-0.013	-0.1896	No
173	EML2	EML2	14507	-0.013	-0.1895	No
174	N4BP2L1	N4BP2L1	14589	-0.013	-0.1917	No
175	GOSR2	GOSR2	14718	-0.014	-0.1960	No
176	TMEM97	TMEM97	14730	-0.014	-0.1949	No
177	AKNA	AKNA	14787	-0.014	-0.1958	No
178	FGFBP3	FGFBP3	14791	-0.014	-0.1943	No
179	CDKN1A	CDKN1A	14918	-0.014	-0.1985	No
180	TBC1D15	TBC1D15	15156	-0.015	-0.2077	No
181	SLC22A18	SLC22A18	15179	-0.016	-0.2069	No
182	JAK3	JAK3	15181	-0.016	-0.2051	No
183	APOE	APOE	15188	-0.016	-0.2035	No
184	TPST1	TPST1	15205	-0.016	-0.2023	No
185	GCNT4	GCNT4	15337	-0.016	-0.2065	No
186	WIPI1	WIPI1	15356	-0.016	-0.2054	No
187	PLSCR4	PLSCR4	15367	-0.016	-0.2040	No
188	COL11A2	COL11A2	15475	-0.017	-0.2070	No
189	SYN3	SYN3	15537	-0.017	-0.2078	No
190	KLF9	KLF9	15550	-0.017	-0.2063	No
191	SLC2A4	SLC2A4	15768	-0.018	-0.2143	No
192	GOLGA2	GOLGA2	15779	-0.018	-0.2126	No
193	TMEM120A	TMEM120A	15962	-0.019	-0.2189	No
194	PITPNC1	PITPNC1	16013	-0.019	-0.2189	No
195	TBC1D23	TBC1D23	16014	-0.019	-0.2166	No
196	TIMP1	TIMP1	16033	-0.019	-0.2152	No
197	MEIS3	MEIS3	16068	-0.019	-0.2144	No
198	TMEM173	TMEM173	16087	-0.019	-0.2129	No
199	PRICKLE2	PRICKLE2	16208	-0.020	-0.2162	No
200	ULBP2	ULBP2	16324	-0.021	-0.2191	No
201	DNAJB5	DNAJB5	16434	-0.021	-0.2217	No
202	PDK4	PDK4	16555	-0.022	-0.2247	No
203	SYDE2	SYDE2	16648	-0.022	-0.2264	No
204	NUAK2	NUAK2	16714	-0.022	-0.2267	No
205	ATCAY	ATCAY	16784	-0.023	-0.2272	No
206	CBWD5	CBWD5	16814	-0.023	-0.2259	No
207	SYNM	SYNM	16956	-0.023	-0.2297	No
208	TXNIP	TXNIP	17036	-0.024	-0.2305	No
209	ARF4	ARF4	17210	-0.025	-0.2356	No
210	HABP4	HABP4	17367	-0.025	-0.2399	No
211	POLR3D	POLR3D	17376	-0.026	-0.2372	No
212	TRIM7	TRIM7	17458	-0.026	-0.2379	No
213	F3	F3	17464	-0.026	-0.2350	No
214	ZFP36	ZFP36	17472	-0.026	-0.2322	No
215	CCNB1IP1	CCNB1IP1	17578	-0.027	-0.2339	No
216	GOLGA5	GOLGA5	17579	-0.027	-0.2307	No
217	TRPM8	TRPM8	17614	-0.027	-0.2290	No
218	ZNF608	ZNF608	17618	-0.027	-0.2259	No
219	FTL	FTL	17640	-0.027	-0.2237	No
220	RAB4A	RAB4A	17755	-0.028	-0.2257	No
221	FUT1	FUT1	17919	-0.029	-0.2299	No
222	ZFPL1	ZFPL1	17976	-0.029	-0.2290	No
223	PODXL	PODXL	18139	-0.030	-0.2330	No
224	CLDN4	CLDN4	18245	-0.031	-0.2343	No
225	AOC2	AOC2	18353	-0.031	-0.2355	No
226	APOL6	APOL6	18357	-0.031	-0.2319	No
227	TNFRSF1A	TNFRSF1A	18376	-0.031	-0.2289	No
228	GPX3	GPX3	18429	-0.032	-0.2276	No
229	FABP3	FABP3	18525	-0.032	-0.2281	No
230	RCN3	RCN3	18598	-0.033	-0.2276	No
231	CBS	CBS	18899	-0.035	-0.2375	No
232	EPHX1	EPHX1	18947	-0.035	-0.2355	No
233	ABCD2	ABCD2	18967	-0.035	-0.2321	No
234	DTX3L	DTX3L	19343	-0.038	-0.2451	Yes
235	ACAN	ACAN	19414	-0.039	-0.2437	Yes
236	CDKL3	CDKL3	19504	-0.039	-0.2432	Yes
237	GREM2	GREM2	19639	-0.041	-0.2446	Yes
238	EFNA1	EFNA1	19748	-0.042	-0.2446	Yes
239	CISH	CISH	19838	-0.043	-0.2437	Yes
240	ENO3	ENO3	19882	-0.043	-0.2405	Yes
241	CCDC113	CCDC113	19895	-0.043	-0.2359	Yes
242	LIFR	LIFR	19899	-0.043	-0.2308	Yes
243	C1QL1	C1QL1	19916	-0.044	-0.2263	Yes
244	LMAN1	LMAN1	20047	-0.045	-0.2270	Yes
245	CITED1	CITED1	20122	-0.046	-0.2249	Yes
246	NPC2	NPC2	20205	-0.047	-0.2231	Yes
247	ITGA10	ITGA10	20207	-0.047	-0.2175	Yes
248	COG6	COG6	20280	-0.048	-0.2151	Yes
249	YPEL3	YPEL3	20281	-0.048	-0.2094	Yes
250	DBP	DBP	20367	-0.049	-0.2074	Yes
251	ANKRD20A4	ANKRD20A4	20426	-0.050	-0.2041	Yes
252	GADD45A	GADD45A	20448	-0.051	-0.1990	Yes
253	PIM1	PIM1	20458	-0.051	-0.1933	Yes
254	CYB561D2	CYB561D2	20550	-0.052	-0.1913	Yes
255	A2M	A2M	20660	-0.055	-0.1899	Yes
256	MYCN	MYCN	20661	-0.055	-0.1833	Yes
257	STK19	STK19	20680	-0.055	-0.1776	Yes
258	PIK3IP1	PIK3IP1	20797	-0.057	-0.1761	Yes
259	ATP1B2	ATP1B2	20813	-0.058	-0.1699	Yes
260	CIB1	CIB1	20907	-0.060	-0.1670	Yes
261	HLA-E	HLA-E	20930	-0.061	-0.1608	Yes
262	YIPF2	YIPF2	20994	-0.063	-0.1562	Yes
263	KDELR3	KDELR3	20996	-0.063	-0.1487	Yes
264	VGF	VGF	21040	-0.064	-0.1430	Yes
265	C12orf76	C12orf76	21193	-0.070	-0.1418	Yes
266	CRYAB	CRYAB	21443	-0.089	-0.1427	Yes
267	ISG20	ISG20	21453	-0.091	-0.1322	Yes
268	IFITM2	IFITM2	21470	-0.093	-0.1217	Yes
269	NUPR1	NUPR1	21514	-0.103	-0.1114	Yes
270	IRF9	IRF9	21517	-0.103	-0.0991	Yes
271	PLA2G4C	PLA2G4C	21551	-0.117	-0.0867	Yes
272	IFITM1	IFITM1	21556	-0.120	-0.0725	Yes
273	MCEE	MCEE	21560	-0.125	-0.0576	Yes
274	PMP2	PMP2	21584	-0.157	-0.0398	Yes
275	BST2	BST2	21587	-0.164	-0.0201	Yes
276	MATN2	MATN2	21589	-0.170	0.0003	Yes