DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetPOU3F3_REGULON
Enrichment Score (ES)0.21948913
Normalized Enrichment Score (NES)0.94285506
Nominal p-value0.5808656
FDR q-value0.59351146
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: POU3F3_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LRRFIP1LRRFIP150.1370.0518Yes
2CARD10CARD10510.1000.0875Yes
3PTCD3PTCD31500.0830.1144Yes
4ELOVL5ELOVL512500.0470.0810Yes
5SV2ASV2A13000.0460.0962Yes
6CACNB2CACNB213530.0450.1109Yes
7PSD3PSD313630.0450.1276Yes
8FHL2FHL214930.0430.1381Yes
9LUZP1LUZP115930.0430.1497Yes
10BCL2L1BCL2L117300.0410.1590Yes
11CRTC1CRTC120050.0390.1609Yes
12EFR3BEFR3B23050.0360.1606Yes
13KLF12KLF1224730.0350.1660Yes
14C1orf21C1orf2125950.0340.1732Yes
15EHD4EHD426890.0330.1815Yes
16IBTKIBTK30500.0310.1764Yes
17KCNA2KCNA230710.0310.1871Yes
18ATICATIC30810.0300.1982Yes
19FZD3FZD330870.0300.2095Yes
20GOLPH3GOLPH331450.0300.2183Yes
21ZNF117ZNF11735650.0270.2092Yes
22ZNF24ZNF2436040.0270.2178Yes
23EXTL3EXTL337820.0260.2195Yes
24HPS5HPS544440.0230.1974No
25TLE1TLE147660.0210.1906No
26KANK1KANK148590.0210.1942No
27DPP6DPP651040.0200.1904No
28ACSL1ACSL151300.0200.1967No
29ADD2ADD251630.0200.2026No
30TRIM37TRIM3753340.0190.2018No
31KIF1BKIF1B54550.0180.2031No
32PDE4BPDE4B60420.0160.1818No
33TRPM3TRPM360590.0160.1870No
34KLHL25KLHL2563250.0150.1802No
35CDH4CDH463790.0140.1832No
36RGS12RGS1267240.0130.1721No
37RNMTRNMT71330.0120.1575No
38RFX4RFX479040.0090.1251No
39FLRT1FLRT181460.0080.1169No
40TMEM123TMEM12387740.0060.0901No
41RAB11FIP2RAB11FIP289180.0060.0855No
42ZNF253ZNF25391030.0050.0788No
43PURGPURG95220.0040.0608No
44UTYUTY96200.0030.0575No
45TBPL1TBPL197810.0030.0511No
46PCDH9PCDH998500.0020.0488No
47DNMT3ADNMT3A103100.0010.0279No
48SALL1SALL1106180.0000.0137No
49SCP2SCP210700-0.0000.0099No
50SLC7A1SLC7A110948-0.001-0.0012No
51CACNG4CACNG411146-0.002-0.0098No
52TARSTARS11342-0.002-0.0180No
53PBX1PBX111395-0.002-0.0195No
54RFX2RFX212049-0.005-0.0482No
55TUBA1ATUBA1A12515-0.006-0.0675No
56UTP6UTP613423-0.009-0.1062No
57RAI14RAI1413643-0.010-0.1127No
58GPRC5BGPRC5B13715-0.010-0.1122No
59DZIP3DZIP313776-0.010-0.1111No
60ATF7IPATF7IP13904-0.011-0.1129No
61SRPK2SRPK213946-0.011-0.1107No
62FABP7FABP714093-0.011-0.1132No
63P2RY1P2RY114374-0.012-0.1215No
64TNIP1TNIP114388-0.012-0.1174No
65HP1BP3HP1BP314549-0.013-0.1199No
66LPIN1LPIN114700-0.014-0.1217No
67FXYD5FXYD514924-0.014-0.1265No
68PIK3C2BPIK3C2B14984-0.015-0.1237No
69CACNG1CACNG115275-0.016-0.1311No
70TMEM156TMEM15615326-0.016-0.1273No
71HIP1HIP115693-0.018-0.1377No
72C4orf19C4orf1915905-0.019-0.1404No
73NSL1NSL116698-0.022-0.1688No
74SSBP2SSBP216700-0.022-0.1604No
75GLULGLUL16877-0.023-0.1598No
76TMCO1TMCO116914-0.023-0.1526No
77MEIS2MEIS217076-0.024-0.1510No
78C11orf49C11orf4918227-0.031-0.1929No
79TEKT2TEKT218606-0.033-0.1981No
80ARL3ARL318627-0.033-0.1865No
81ZKSCAN3ZKSCAN318909-0.035-0.1863No
82ABCD2ABCD218967-0.035-0.1756No
83SPATA6SPATA619249-0.037-0.1744No
84ERI3ERI319381-0.039-0.1659No
85STMN3STMN319531-0.040-0.1578No
86MYO1CMYO1C19667-0.041-0.1485No
87KLHDC8AKLHDC8A19821-0.042-0.1395No
88DUSP11DUSP1119870-0.043-0.1254No
89FAM131BFAM131B19958-0.044-0.1127No
90ING4ING420331-0.049-0.1115No
91VPS72VPS7220799-0.057-0.1115No
92CREG1CREG120852-0.058-0.0917No
93NCALDNCALD21072-0.065-0.0772No
94GAS1GAS121567-0.130-0.0507No
95TTYH1TTYH121573-0.1370.0011No
Table: GSEA details [plain text format]



Fig 2: POU3F3_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POU3F3_REGULON: Random ES distribution   
Gene set null distribution of ES for POU3F3_REGULON