DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetPHILLIPS_PROLIFERATIVE_2006
Enrichment Score (ES)0.37314028
Normalized Enrichment Score (NES)1.7831552
Nominal p-value0.0
FDR q-value0.0017542485
FWER p-Value0.008
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_PROLIFERATIVE_2006   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1C3orf34C3orf34160.1190.0230Yes
2RRM2RRM2670.0950.0398Yes
3MDFICMDFIC2710.0720.0447Yes
4DTLDTL2780.0720.0588Yes
5ZWILCHZWILCH3110.0700.0713Yes
6E2F1E2F13140.0700.0851Yes
7AURKAAURKA3260.0690.0985Yes
8MCM2MCM23270.0690.1123Yes
9LMNB1LMNB13370.0680.1255Yes
10CCNE2CCNE23440.0680.1389Yes
11NCAPGNCAPG3990.0660.1495Yes
12HMMRHMMR4190.0650.1616Yes
13CENPFCENPF5040.0610.1700Yes
14DLGAP5DLGAP55170.0610.1816Yes
15KIF23KIF235210.0610.1935Yes
16EIF1AXEIF1AX5400.0600.2048Yes
17ECT2ECT25650.0600.2156Yes
18KIF14KIF146080.0590.2253Yes
19TTKTTK6550.0570.2346Yes
20RECQLRECQL7170.0560.2430Yes
21SGOL2SGOL27290.0560.2536Yes
22CCNA2CCNA29360.0520.2543Yes
23ASPMASPM9500.0510.2640Yes
24ITGA2ITGA210150.0500.2711Yes
25HJURPHJURP12200.0470.2710Yes
26CENPLCENPL15310.0430.2651Yes
27EMP2EMP215490.0430.2729Yes
28CENPECENPE16270.0420.2777Yes
29CEP152CEP15217320.0410.2811Yes
30BUB1BUB117410.0410.2890Yes
31DEKDEK18180.0400.2935Yes
32RRM1RRM119710.0390.2941Yes
33DBF4DBF419780.0390.3016Yes
34GMPSGMPS21010.0380.3034Yes
35KIF4AKIF4A21090.0380.3106Yes
36PLK4PLK421180.0380.3177Yes
37WEE1WEE122180.0370.3205Yes
38STILSTIL22460.0360.3265Yes
39PCNAPCNA22900.0360.3317Yes
40TOP2ATOP2A23600.0360.3356Yes
41SPIN4SPIN423650.0360.3425Yes
42NUF2NUF224000.0350.3480Yes
43FBXO5FBXO524040.0350.3549Yes
44NEK2NEK225780.0340.3536Yes
45NUSAP1NUSAP126260.0340.3581Yes
46LRIG3LRIG326650.0330.3630Yes
47C12orf48C12orf4828990.0320.3584Yes
48PRPS2PRPS229170.0320.3639Yes
49SMC4SMC430880.0300.3621Yes
50MLF1IPMLF1IP32030.0300.3627Yes
51NDC80NDC8032600.0290.3659Yes
52WDHD1WDHD133780.0290.3662Yes
53ZNF367ZNF36734550.0280.3683Yes
54DHFRDHFR34710.0280.3731Yes
55NUCB2NUCB238160.0260.3623No
56CDC6CDC639030.0260.3634No
57CDKN2CCDKN2C41930.0240.3547No
58MAD2L1MAD2L142160.0240.3584No
59TOM1L1TOM1L142520.0240.3616No
60FBXO11FBXO1142970.0240.3642No
61GCLMGCLM43790.0230.3651No
62SLC25A24SLC25A2445110.0230.3634No
63PPIGPPIG45280.0220.3672No
64SMC2SMC245880.0220.3689No
65CENPKCENPK49880.0200.3543No
66CENPICENPI51930.0190.3486No
67BARD1BARD155080.0180.3376No
68RAD51AP1RAD51AP156280.0170.3355No
69HAUS6HAUS656810.0170.3365No
70PEG10PEG1061830.0150.3161No
71FANCIFANCI62930.0150.3140No
72CDC25CCDC25C64070.0140.3115No
73MELKMELK66170.0130.3045No
74SHFM1SHFM168400.0130.2966No
75RBM24RBM2471430.0110.2848No
76PAWRPAWR72050.0110.2842No
77ZWINTZWINT77550.0090.2605No
78C6orf173C6orf17377940.0090.2606No
79SPC24SPC2478360.0090.2605No
80PPIL5PPIL578600.0090.2612No
81MND1MND181150.0080.2510No
82ORC6LORC6L83260.0080.2427No
83C1orf133C1orf13383520.0070.2430No
84YEATS4YEATS484970.0070.2377No
85CDKN2ACDKN2A84980.0070.2391No
86KIAA0101KIAA010186930.0060.2313No
87EZH2EZH287540.0060.2297No
88KIAA0895KIAA089588370.0060.2270No
89NCAPHNCAPH89200.0060.2243No
90HMGB2HMGB289320.0060.2249No
91RAD51RAD5189990.0050.2229No
92DSN1DSN190060.0050.2236No
93E2F7E2F791770.0050.2166No
94ITGB3BPITGB3BP95180.0040.2015No
95CCNB1CCNB195340.0040.2015No
96GJC1GJC197910.0030.1901No
97CREBZFCREBZF99490.0020.1832No
98CDK2CDK299770.0020.1823No
99CENPACENPA100220.0020.1807No
100E2F8E2F8101050.0020.1772No
101TEX9TEX9103920.0010.1640No
102PAIP1PAIP1105110.0000.1586No
103KIF18AKIF18A105330.0000.1577No
104HELLSHELLS10654-0.0000.1521No
105TTC26TTC2611389-0.0020.1183No
106CHAF1BCHAF1B11706-0.0030.1042No
107RBBP8RBBP811848-0.0040.0984No
108MAGOHBMAGOHB11889-0.0040.0973No
109MCM6MCM611922-0.0040.0966No
110IL13RA2IL13RA211965-0.0040.0955No
111GINS1GINS112068-0.0050.0917No
112IFT74IFT7412136-0.0050.0896No
113PDK1PDK112184-0.0050.0884No
114SIP1SIP112214-0.0050.0880No
115TIMELESSTIMELESS12249-0.0050.0875No
116GGHGGH12373-0.0060.0829No
117BRCA1BRCA112386-0.0060.0835No
118KNTC1KNTC112528-0.0060.0781No
119FANCD2FANCD212570-0.0060.0774No
120DONSONDONSON12583-0.0060.0782No
121PABPC4LPABPC4L12978-0.0080.0613No
122CHEK1CHEK113220-0.0080.0517No
123C1orf112C1orf11213394-0.0090.0454No
124ABHD3ABHD313401-0.0090.0469No
125ZC3HAV1LZC3HAV1L13510-0.0090.0437No
126MNS1MNS113714-0.0100.0363No
127TMEM38BTMEM38B13782-0.0100.0352No
128WDR34WDR3414036-0.0110.0256No
129LSM5LSM514246-0.0120.0183No
130RFC4RFC414295-0.0120.0184No
131TCF19TCF1914364-0.0120.0177No
132SHOX2SHOX214494-0.0130.0143No
133ANKRD5ANKRD514550-0.0130.0143No
134CCDC138CCDC13814706-0.0140.0098No
135ANKRD32ANKRD3215061-0.015-0.0037No
136CKS2CKS215081-0.015-0.0016No
137NASPNASP15306-0.016-0.0088No
138CHAF1ACHAF1A15565-0.017-0.0174No
139TYMSTYMS15597-0.017-0.0154No
140TTC12TTC1215975-0.019-0.0293No
141TRIM36TRIM3616112-0.020-0.0317No
142CENPNCENPN16724-0.022-0.0557No
143ERCC6LERCC6L16895-0.023-0.0590No
144TIFATIFA17139-0.024-0.0655No
145TMEM14BTMEM14B17263-0.025-0.0663No
146CDC2CDC217468-0.026-0.0706No
147TMPOTMPO17776-0.028-0.0794No
148C17orf75C17orf7517833-0.028-0.0763No
149ARNTL2ARNTL217840-0.028-0.0710No
150XRCC4XRCC418053-0.030-0.0749No
151TMEM79TMEM7918147-0.030-0.0733No
152CDCA7CDCA718427-0.032-0.0800No
153ACN9ACN918689-0.033-0.0855No
154PIN4PIN418832-0.034-0.0852No
155NPHP1NPHP118898-0.035-0.0813No
156TRMT6TRMT619050-0.036-0.0812No
157MLF1MLF119200-0.037-0.0807No
158EXOSC9EXOSC919308-0.038-0.0781No
159USP1USP119375-0.038-0.0735No
160TMEM106CTMEM106C19588-0.040-0.0754No
161MAGOHMAGOH19634-0.041-0.0694No
162MTF2MTF219651-0.041-0.0620No
163C3orf14C3orf1419700-0.041-0.0560No
164CCDC34CCDC3419746-0.042-0.0497No
165EVC2EVC219764-0.042-0.0422No
166RPA3RPA319805-0.042-0.0356No
167ATG12ATG1219992-0.045-0.0354No
168PRIM2PRIM220260-0.048-0.0383No
169ACYP1ACYP120304-0.048-0.0306No
170CACYBPCACYBP20569-0.053-0.0324No
171C4orf47C4orf4720609-0.054-0.0235No
172ABCA5ABCA520650-0.054-0.0145No
173PPICPPIC20717-0.056-0.0064No
174EFCAB2EFCAB220766-0.0570.0027No
175C3orf15C3orf1520823-0.0580.0116No
176GINS2GINS220871-0.0590.0212No
177C1orf97C1orf9721011-0.0630.0273No
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_PROLIFERATIVE_2006   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_PROLIFERATIVE_2006: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_PROLIFERATIVE_2006