Dataset | shNF1_exprs.shNF1_phenotype.cls #shNF1_versus_shCtrl.shNF1_phenotype.cls #shNF1_versus_shCtrl_repos |
Phenotype | shNF1_phenotype.cls#shNF1_versus_shCtrl_repos |
Upregulated in class | shNF1 |
GeneSet | PHILLIPS_PROLIFERATIVE_2006 |
Enrichment Score (ES) | 0.37314028 |
Normalized Enrichment Score (NES) | 1.7831552 |
Nominal p-value | 0.0 |
FDR q-value | 0.0017542485 |
FWER p-Value | 0.008 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | C3orf34 | C3orf34 | 16 | 0.119 | 0.0230 | Yes |
2 | RRM2 | RRM2 | 67 | 0.095 | 0.0398 | Yes |
3 | MDFIC | MDFIC | 271 | 0.072 | 0.0447 | Yes |
4 | DTL | DTL | 278 | 0.072 | 0.0588 | Yes |
5 | ZWILCH | ZWILCH | 311 | 0.070 | 0.0713 | Yes |
6 | E2F1 | E2F1 | 314 | 0.070 | 0.0851 | Yes |
7 | AURKA | AURKA | 326 | 0.069 | 0.0985 | Yes |
8 | MCM2 | MCM2 | 327 | 0.069 | 0.1123 | Yes |
9 | LMNB1 | LMNB1 | 337 | 0.068 | 0.1255 | Yes |
10 | CCNE2 | CCNE2 | 344 | 0.068 | 0.1389 | Yes |
11 | NCAPG | NCAPG | 399 | 0.066 | 0.1495 | Yes |
12 | HMMR | HMMR | 419 | 0.065 | 0.1616 | Yes |
13 | CENPF | CENPF | 504 | 0.061 | 0.1700 | Yes |
14 | DLGAP5 | DLGAP5 | 517 | 0.061 | 0.1816 | Yes |
15 | KIF23 | KIF23 | 521 | 0.061 | 0.1935 | Yes |
16 | EIF1AX | EIF1AX | 540 | 0.060 | 0.2048 | Yes |
17 | ECT2 | ECT2 | 565 | 0.060 | 0.2156 | Yes |
18 | KIF14 | KIF14 | 608 | 0.059 | 0.2253 | Yes |
19 | TTK | TTK | 655 | 0.057 | 0.2346 | Yes |
20 | RECQL | RECQL | 717 | 0.056 | 0.2430 | Yes |
21 | SGOL2 | SGOL2 | 729 | 0.056 | 0.2536 | Yes |
22 | CCNA2 | CCNA2 | 936 | 0.052 | 0.2543 | Yes |
23 | ASPM | ASPM | 950 | 0.051 | 0.2640 | Yes |
24 | ITGA2 | ITGA2 | 1015 | 0.050 | 0.2711 | Yes |
25 | HJURP | HJURP | 1220 | 0.047 | 0.2710 | Yes |
26 | CENPL | CENPL | 1531 | 0.043 | 0.2651 | Yes |
27 | EMP2 | EMP2 | 1549 | 0.043 | 0.2729 | Yes |
28 | CENPE | CENPE | 1627 | 0.042 | 0.2777 | Yes |
29 | CEP152 | CEP152 | 1732 | 0.041 | 0.2811 | Yes |
30 | BUB1 | BUB1 | 1741 | 0.041 | 0.2890 | Yes |
31 | DEK | DEK | 1818 | 0.040 | 0.2935 | Yes |
32 | RRM1 | RRM1 | 1971 | 0.039 | 0.2941 | Yes |
33 | DBF4 | DBF4 | 1978 | 0.039 | 0.3016 | Yes |
34 | GMPS | GMPS | 2101 | 0.038 | 0.3034 | Yes |
35 | KIF4A | KIF4A | 2109 | 0.038 | 0.3106 | Yes |
36 | PLK4 | PLK4 | 2118 | 0.038 | 0.3177 | Yes |
37 | WEE1 | WEE1 | 2218 | 0.037 | 0.3205 | Yes |
38 | STIL | STIL | 2246 | 0.036 | 0.3265 | Yes |
39 | PCNA | PCNA | 2290 | 0.036 | 0.3317 | Yes |
40 | TOP2A | TOP2A | 2360 | 0.036 | 0.3356 | Yes |
41 | SPIN4 | SPIN4 | 2365 | 0.036 | 0.3425 | Yes |
42 | NUF2 | NUF2 | 2400 | 0.035 | 0.3480 | Yes |
43 | FBXO5 | FBXO5 | 2404 | 0.035 | 0.3549 | Yes |
44 | NEK2 | NEK2 | 2578 | 0.034 | 0.3536 | Yes |
45 | NUSAP1 | NUSAP1 | 2626 | 0.034 | 0.3581 | Yes |
46 | LRIG3 | LRIG3 | 2665 | 0.033 | 0.3630 | Yes |
47 | C12orf48 | C12orf48 | 2899 | 0.032 | 0.3584 | Yes |
48 | PRPS2 | PRPS2 | 2917 | 0.032 | 0.3639 | Yes |
49 | SMC4 | SMC4 | 3088 | 0.030 | 0.3621 | Yes |
50 | MLF1IP | MLF1IP | 3203 | 0.030 | 0.3627 | Yes |
51 | NDC80 | NDC80 | 3260 | 0.029 | 0.3659 | Yes |
52 | WDHD1 | WDHD1 | 3378 | 0.029 | 0.3662 | Yes |
53 | ZNF367 | ZNF367 | 3455 | 0.028 | 0.3683 | Yes |
54 | DHFR | DHFR | 3471 | 0.028 | 0.3731 | Yes |
55 | NUCB2 | NUCB2 | 3816 | 0.026 | 0.3623 | No |
56 | CDC6 | CDC6 | 3903 | 0.026 | 0.3634 | No |
57 | CDKN2C | CDKN2C | 4193 | 0.024 | 0.3547 | No |
58 | MAD2L1 | MAD2L1 | 4216 | 0.024 | 0.3584 | No |
59 | TOM1L1 | TOM1L1 | 4252 | 0.024 | 0.3616 | No |
60 | FBXO11 | FBXO11 | 4297 | 0.024 | 0.3642 | No |
61 | GCLM | GCLM | 4379 | 0.023 | 0.3651 | No |
62 | SLC25A24 | SLC25A24 | 4511 | 0.023 | 0.3634 | No |
63 | PPIG | PPIG | 4528 | 0.022 | 0.3672 | No |
64 | SMC2 | SMC2 | 4588 | 0.022 | 0.3689 | No |
65 | CENPK | CENPK | 4988 | 0.020 | 0.3543 | No |
66 | CENPI | CENPI | 5193 | 0.019 | 0.3486 | No |
67 | BARD1 | BARD1 | 5508 | 0.018 | 0.3376 | No |
68 | RAD51AP1 | RAD51AP1 | 5628 | 0.017 | 0.3355 | No |
69 | HAUS6 | HAUS6 | 5681 | 0.017 | 0.3365 | No |
70 | PEG10 | PEG10 | 6183 | 0.015 | 0.3161 | No |
71 | FANCI | FANCI | 6293 | 0.015 | 0.3140 | No |
72 | CDC25C | CDC25C | 6407 | 0.014 | 0.3115 | No |
73 | MELK | MELK | 6617 | 0.013 | 0.3045 | No |
74 | SHFM1 | SHFM1 | 6840 | 0.013 | 0.2966 | No |
75 | RBM24 | RBM24 | 7143 | 0.011 | 0.2848 | No |
76 | PAWR | PAWR | 7205 | 0.011 | 0.2842 | No |
77 | ZWINT | ZWINT | 7755 | 0.009 | 0.2605 | No |
78 | C6orf173 | C6orf173 | 7794 | 0.009 | 0.2606 | No |
79 | SPC24 | SPC24 | 7836 | 0.009 | 0.2605 | No |
80 | PPIL5 | PPIL5 | 7860 | 0.009 | 0.2612 | No |
81 | MND1 | MND1 | 8115 | 0.008 | 0.2510 | No |
82 | ORC6L | ORC6L | 8326 | 0.008 | 0.2427 | No |
83 | C1orf133 | C1orf133 | 8352 | 0.007 | 0.2430 | No |
84 | YEATS4 | YEATS4 | 8497 | 0.007 | 0.2377 | No |
85 | CDKN2A | CDKN2A | 8498 | 0.007 | 0.2391 | No |
86 | KIAA0101 | KIAA0101 | 8693 | 0.006 | 0.2313 | No |
87 | EZH2 | EZH2 | 8754 | 0.006 | 0.2297 | No |
88 | KIAA0895 | KIAA0895 | 8837 | 0.006 | 0.2270 | No |
89 | NCAPH | NCAPH | 8920 | 0.006 | 0.2243 | No |
90 | HMGB2 | HMGB2 | 8932 | 0.006 | 0.2249 | No |
91 | RAD51 | RAD51 | 8999 | 0.005 | 0.2229 | No |
92 | DSN1 | DSN1 | 9006 | 0.005 | 0.2236 | No |
93 | E2F7 | E2F7 | 9177 | 0.005 | 0.2166 | No |
94 | ITGB3BP | ITGB3BP | 9518 | 0.004 | 0.2015 | No |
95 | CCNB1 | CCNB1 | 9534 | 0.004 | 0.2015 | No |
96 | GJC1 | GJC1 | 9791 | 0.003 | 0.1901 | No |
97 | CREBZF | CREBZF | 9949 | 0.002 | 0.1832 | No |
98 | CDK2 | CDK2 | 9977 | 0.002 | 0.1823 | No |
99 | CENPA | CENPA | 10022 | 0.002 | 0.1807 | No |
100 | E2F8 | E2F8 | 10105 | 0.002 | 0.1772 | No |
101 | TEX9 | TEX9 | 10392 | 0.001 | 0.1640 | No |
102 | PAIP1 | PAIP1 | 10511 | 0.000 | 0.1586 | No |
103 | KIF18A | KIF18A | 10533 | 0.000 | 0.1577 | No |
104 | HELLS | HELLS | 10654 | -0.000 | 0.1521 | No |
105 | TTC26 | TTC26 | 11389 | -0.002 | 0.1183 | No |
106 | CHAF1B | CHAF1B | 11706 | -0.003 | 0.1042 | No |
107 | RBBP8 | RBBP8 | 11848 | -0.004 | 0.0984 | No |
108 | MAGOHB | MAGOHB | 11889 | -0.004 | 0.0973 | No |
109 | MCM6 | MCM6 | 11922 | -0.004 | 0.0966 | No |
110 | IL13RA2 | IL13RA2 | 11965 | -0.004 | 0.0955 | No |
111 | GINS1 | GINS1 | 12068 | -0.005 | 0.0917 | No |
112 | IFT74 | IFT74 | 12136 | -0.005 | 0.0896 | No |
113 | PDK1 | PDK1 | 12184 | -0.005 | 0.0884 | No |
114 | SIP1 | SIP1 | 12214 | -0.005 | 0.0880 | No |
115 | TIMELESS | TIMELESS | 12249 | -0.005 | 0.0875 | No |
116 | GGH | GGH | 12373 | -0.006 | 0.0829 | No |
117 | BRCA1 | BRCA1 | 12386 | -0.006 | 0.0835 | No |
118 | KNTC1 | KNTC1 | 12528 | -0.006 | 0.0781 | No |
119 | FANCD2 | FANCD2 | 12570 | -0.006 | 0.0774 | No |
120 | DONSON | DONSON | 12583 | -0.006 | 0.0782 | No |
121 | PABPC4L | PABPC4L | 12978 | -0.008 | 0.0613 | No |
122 | CHEK1 | CHEK1 | 13220 | -0.008 | 0.0517 | No |
123 | C1orf112 | C1orf112 | 13394 | -0.009 | 0.0454 | No |
124 | ABHD3 | ABHD3 | 13401 | -0.009 | 0.0469 | No |
125 | ZC3HAV1L | ZC3HAV1L | 13510 | -0.009 | 0.0437 | No |
126 | MNS1 | MNS1 | 13714 | -0.010 | 0.0363 | No |
127 | TMEM38B | TMEM38B | 13782 | -0.010 | 0.0352 | No |
128 | WDR34 | WDR34 | 14036 | -0.011 | 0.0256 | No |
129 | LSM5 | LSM5 | 14246 | -0.012 | 0.0183 | No |
130 | RFC4 | RFC4 | 14295 | -0.012 | 0.0184 | No |
131 | TCF19 | TCF19 | 14364 | -0.012 | 0.0177 | No |
132 | SHOX2 | SHOX2 | 14494 | -0.013 | 0.0143 | No |
133 | ANKRD5 | ANKRD5 | 14550 | -0.013 | 0.0143 | No |
134 | CCDC138 | CCDC138 | 14706 | -0.014 | 0.0098 | No |
135 | ANKRD32 | ANKRD32 | 15061 | -0.015 | -0.0037 | No |
136 | CKS2 | CKS2 | 15081 | -0.015 | -0.0016 | No |
137 | NASP | NASP | 15306 | -0.016 | -0.0088 | No |
138 | CHAF1A | CHAF1A | 15565 | -0.017 | -0.0174 | No |
139 | TYMS | TYMS | 15597 | -0.017 | -0.0154 | No |
140 | TTC12 | TTC12 | 15975 | -0.019 | -0.0293 | No |
141 | TRIM36 | TRIM36 | 16112 | -0.020 | -0.0317 | No |
142 | CENPN | CENPN | 16724 | -0.022 | -0.0557 | No |
143 | ERCC6L | ERCC6L | 16895 | -0.023 | -0.0590 | No |
144 | TIFA | TIFA | 17139 | -0.024 | -0.0655 | No |
145 | TMEM14B | TMEM14B | 17263 | -0.025 | -0.0663 | No |
146 | CDC2 | CDC2 | 17468 | -0.026 | -0.0706 | No |
147 | TMPO | TMPO | 17776 | -0.028 | -0.0794 | No |
148 | C17orf75 | C17orf75 | 17833 | -0.028 | -0.0763 | No |
149 | ARNTL2 | ARNTL2 | 17840 | -0.028 | -0.0710 | No |
150 | XRCC4 | XRCC4 | 18053 | -0.030 | -0.0749 | No |
151 | TMEM79 | TMEM79 | 18147 | -0.030 | -0.0733 | No |
152 | CDCA7 | CDCA7 | 18427 | -0.032 | -0.0800 | No |
153 | ACN9 | ACN9 | 18689 | -0.033 | -0.0855 | No |
154 | PIN4 | PIN4 | 18832 | -0.034 | -0.0852 | No |
155 | NPHP1 | NPHP1 | 18898 | -0.035 | -0.0813 | No |
156 | TRMT6 | TRMT6 | 19050 | -0.036 | -0.0812 | No |
157 | MLF1 | MLF1 | 19200 | -0.037 | -0.0807 | No |
158 | EXOSC9 | EXOSC9 | 19308 | -0.038 | -0.0781 | No |
159 | USP1 | USP1 | 19375 | -0.038 | -0.0735 | No |
160 | TMEM106C | TMEM106C | 19588 | -0.040 | -0.0754 | No |
161 | MAGOH | MAGOH | 19634 | -0.041 | -0.0694 | No |
162 | MTF2 | MTF2 | 19651 | -0.041 | -0.0620 | No |
163 | C3orf14 | C3orf14 | 19700 | -0.041 | -0.0560 | No |
164 | CCDC34 | CCDC34 | 19746 | -0.042 | -0.0497 | No |
165 | EVC2 | EVC2 | 19764 | -0.042 | -0.0422 | No |
166 | RPA3 | RPA3 | 19805 | -0.042 | -0.0356 | No |
167 | ATG12 | ATG12 | 19992 | -0.045 | -0.0354 | No |
168 | PRIM2 | PRIM2 | 20260 | -0.048 | -0.0383 | No |
169 | ACYP1 | ACYP1 | 20304 | -0.048 | -0.0306 | No |
170 | CACYBP | CACYBP | 20569 | -0.053 | -0.0324 | No |
171 | C4orf47 | C4orf47 | 20609 | -0.054 | -0.0235 | No |
172 | ABCA5 | ABCA5 | 20650 | -0.054 | -0.0145 | No |
173 | PPIC | PPIC | 20717 | -0.056 | -0.0064 | No |
174 | EFCAB2 | EFCAB2 | 20766 | -0.057 | 0.0027 | No |
175 | C3orf15 | C3orf15 | 20823 | -0.058 | 0.0116 | No |
176 | GINS2 | GINS2 | 20871 | -0.059 | 0.0212 | No |
177 | C1orf97 | C1orf97 | 21011 | -0.063 | 0.0273 | No |