DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshCtrl
GeneSetPHILLIPS_PN_2006
Enrichment Score (ES)-0.32946315
Normalized Enrichment Score (NES)-1.5353752
Nominal p-value0.0
FDR q-value0.016571008
FWER p-Value0.136
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_PN_2006   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CNTN1CNTN14520.063-0.0112No
2OPCMLOPCML4970.062-0.0035No
3KSR2KSR25080.0610.0057No
4DNM3DNM35480.0600.0134No
5TPM1TPM16140.0580.0195No
6F2F26410.0580.0274No
7GABRA3GABRA39890.0510.0192No
8SNAP91SNAP9110750.0490.0230No
9NUMA1NUMA111160.0490.0288No
10DSCAML1DSCAML111560.0480.0345No
11PSDPSD11720.0480.0414No
12NOGNOG12600.0470.0446No
13NKAIN4NKAIN413390.0450.0482No
14C12orf53C12orf5314530.0440.0498No
15SSTR2SSTR217660.0410.0416No
16FAM19A5FAM19A518030.0400.0463No
17SHDSHD19030.0390.0479No
18ARHGAP22ARHGAP2219240.0390.0532No
19CRTC1CRTC120050.0390.0555No
20SEZ6LSEZ6L20220.0380.0608No
21FGF14FGF1421870.0370.0590No
22RAB11FIP4RAB11FIP422950.0360.0597No
23NTRK2NTRK224220.0350.0593No
24WDR86WDR8624230.0350.0649No
25RPRMRPRM24690.0350.0683No
26SGCGSGCG25860.0340.0682No
27SLC25A21SLC25A2126690.0330.0696No
28RTN1RTN127370.0330.0716No
29SLITRK5SLITRK527980.0320.0739No
30KCNB1KCNB128030.0320.0788No
31OVOL1OVOL128400.0320.0822No
32EPB41L2EPB41L229880.0310.0802No
33OMGOMG30050.0310.0844No
34GLUD2GLUD230450.0310.0874No
35ZNF488ZNF48832680.0290.0816No
36AP2B1AP2B135550.0280.0726No
37SLC1A1SLC1A136120.0270.0743No
38WNT7BWNT7B36840.0270.0752No
39SLC1A4SLC1A437180.0270.0778No
40FLJ16779FLJ1677940820.0250.0647No
41PLCB1PLCB143370.0230.0565No
42GRIK4GRIK443430.0230.0599No
43psiTPTE22psiTPTE2244590.0230.0581No
44GABBR2GABBR245250.0220.0586No
45CYFIP2CYFIP247050.0220.0537No
46HS3ST4HS3ST448550.0210.0500No
47FGF12FGF1250040.0200.0463No
48P2RY13P2RY1353040.0190.0353No
49AJAP1AJAP153290.0190.0371No
50MMP16MMP1653480.0190.0392No
51FSD1FSD153660.0190.0413No
52PHACTR3PHACTR354910.0180.0384No
53DSCAMDSCAM55270.0180.0396No
54SMOC1SMOC157500.0170.0318No
55TMLHETMLHE58250.0170.0310No
56PARD3PARD358600.0160.0320No
57ASB13ASB1358840.0160.0335No
58PRKCZPRKCZ63420.0140.0144No
59ABLIM3ABLIM364250.0140.0128No
60NCAM1NCAM164260.0140.0150No
61CALCRLCALCRL64850.0140.0145No
62HIP1RHIP1R65080.0140.0156No
63PAR5PAR565960.0140.0137No
64PCSK6PCSK666310.0130.0142No
65KCTD4KCTD466870.0130.0137No
66FSTL5FSTL566930.0130.0156No
67FERMT1FERMT169080.0120.0075No
68FAM133AFAM133A69450.0120.0077No
69DPP10DPP1069510.0120.0094No
70GGTA1GGTA169750.0120.0102No
71MAPK8IP2MAPK8IP270500.0120.0086No
72GNAO1GNAO171340.0120.0066No
73MARCH8MARCH871500.0110.0077No
74ZC3H12BZC3H12B71940.0110.0074No
75FRYFRY72530.0110.0065No
76GFRA1GFRA172660.0110.0077No
77C11orf2C11orf272930.0110.0082No
78AKR1C1AKR1C173620.0110.0067No
79B3GAT1B3GAT173840.0110.0074No
80ACSM5ACSM576980.010-0.0058No
81EFHA2EFHA277520.009-0.0068No
82SCDSCD77760.009-0.0064No
83FBXO2FBXO278040.009-0.0062No
84NTN4NTN480510.008-0.0164No
85FLRT1FLRT181460.008-0.0195No
86ZCCHC24ZCCHC2486300.006-0.0411No
87PTGDSPTGDS87580.006-0.0460No
88KIF21BKIF21B87870.006-0.0464No
89BMP2BMP288850.006-0.0501No
90RASL10ARASL10A89410.006-0.0518No
91RIMS2RIMS290200.005-0.0546No
92IKZF5IKZF590580.005-0.0555No
93RIPPLY2RIPPLY297670.003-0.0882No
94RGS9RGS997890.003-0.0888No
95GALNT13GALNT1398860.002-0.0929No
96NET1NET198950.002-0.0929No
97REPS2REPS299370.002-0.0945No
98KLRC3KLRC3100080.002-0.0974No
99HDAC5HDAC5100700.002-0.1000No
100LRRC4LRRC4101210.002-0.1021No
101PKP4PKP4101830.001-0.1047No
102GPR158GPR158102710.001-0.1086No
103CALN1CALN1103420.001-0.1117No
104CSMD3CSMD3104170.001-0.1151No
105FAM155AFAM155A104740.001-0.1176No
106ELMO1ELMO1105010.000-0.1187No
107SPHKAPSPHKAP105120.000-0.1191No
108NAP1L3NAP1L310763-0.000-0.1308No
109STOX1STOX110795-0.000-0.1321No
110SLIT1SLIT110908-0.001-0.1372No
111CBX7CBX710970-0.001-0.1399No
112EHD3EHD310988-0.001-0.1406No
113TRIM31TRIM3111374-0.002-0.1582No
114FUT9FUT911437-0.003-0.1607No
115FAM110BFAM110B11490-0.003-0.1627No
116PKNOX2PKNOX211744-0.004-0.1740No
117RPL37RPL3711832-0.004-0.1775No
118GABBR1GABBR112173-0.005-0.1926No
119RASGEF1CRASGEF1C12180-0.005-0.1921No
120MAPTMAPT12192-0.005-0.1918No
121SORBS1SORBS112199-0.005-0.1913No
122DOK6DOK612225-0.005-0.1917No
123SORCS3SORCS312363-0.006-0.1972No
124ALDH5A1ALDH5A112447-0.006-0.2001No
125KIF5AKIF5A12467-0.006-0.2001No
126C13orf15C13orf1512550-0.006-0.2029No
127KCNN3KCNN312605-0.006-0.2044No
128TPCN2TPCN212728-0.007-0.2091No
129P2RX7P2RX712774-0.007-0.2101No
130ANKS1BANKS1B12848-0.007-0.2124No
131THRATHRA12849-0.007-0.2112No
132LUZP2LUZP212933-0.007-0.2140No
133TMOD2TMOD212981-0.008-0.2149No
134SMAD9SMAD913239-0.008-0.2256No
135NRG3NRG313312-0.009-0.2276No
136ATRNL1ATRNL113338-0.009-0.2274No
137HSPA12AHSPA12A13516-0.009-0.2342No
138NRSN1NRSN113542-0.009-0.2339No
139SEC31BSEC31B13615-0.010-0.2357No
140GPRC5BGPRC5B13715-0.010-0.2388No
141SUSD5SUSD513751-0.010-0.2388No
142CSDC2CSDC213756-0.010-0.2374No
143GRIA1GRIA113757-0.010-0.2358No
144NDRG2NDRG213872-0.011-0.2395No
145GNALGNAL13906-0.011-0.2393No
146SCN3ASCN3A13980-0.011-0.2410No
147TNKS2TNKS214343-0.012-0.2560No
148MN1MN114447-0.013-0.2588No
149SSTR1SSTR114573-0.013-0.2626No
150RAC3RAC314713-0.014-0.2669No
151LGR5LGR514839-0.014-0.2705No
152GRIA4GRIA414879-0.014-0.2701No
153ABHD6ABHD614951-0.015-0.2711No
154SOX6SOX615079-0.015-0.2747No
155JPH4JPH415142-0.015-0.2751No
156APOEAPOE15188-0.016-0.2748No
157USH1CUSH1C15270-0.016-0.2761No
158GABRB3GABRB315373-0.016-0.2783No
159ZNF804AZNF804A15432-0.017-0.2784No
160SGSM1SGSM115492-0.017-0.2785No
161CNTN3CNTN315542-0.017-0.2781No
162BEND7BEND715669-0.018-0.2812No
163EPHB1EPHB115812-0.018-0.2850No
164FGF13FGF1315887-0.019-0.2855No
165GRID1GRID116020-0.019-0.2887No
166CDR1CDR116240-0.020-0.2957No
167ABLIM1ABLIM116439-0.021-0.3017No
168PDK4PDK416555-0.022-0.3037No
169CCNKCCNK16660-0.022-0.3050No
170GLUD1GLUD116679-0.022-0.3024No
171DNAJC12DNAJC1216742-0.022-0.3017No
172ID4ID416762-0.023-0.2990No
173MPPE1MPPE116945-0.023-0.3039No
174JPH3JPH317299-0.025-0.3164No
175SLITRK2SLITRK217512-0.026-0.3222No
176TMEM100TMEM10017557-0.027-0.3200No
177NALCNNALCN17655-0.027-0.3203No
178MCF2MCF217656-0.027-0.3160No
179RASSF4RASSF417872-0.028-0.3216No
180PLEKHB1PLEKHB117954-0.029-0.3208No
181ADCY2ADCY218088-0.030-0.3223No
182CECR6CECR618226-0.031-0.3239Yes
183TAL1TAL118273-0.031-0.3212Yes
184DUSP26DUSP2618351-0.031-0.3199Yes
185KCNQ5KCNQ518355-0.031-0.3151Yes
186PDE2APDE2A18370-0.031-0.3108Yes
187PDK2PDK218509-0.032-0.3121Yes
188HLFHLF18571-0.033-0.3099Yes
189ARL3ARL318627-0.033-0.3072Yes
190ZDHHC22ZDHHC2218734-0.034-0.3069Yes
191FAIM2FAIM218932-0.035-0.3106Yes
192GAB2GAB218965-0.035-0.3065Yes
193RPL13RPL1319310-0.038-0.3166Yes
194DTX4DTX419579-0.040-0.3228Yes
195GAD1GAD119722-0.041-0.3229Yes
196IL17DIL17D19815-0.042-0.3206Yes
197CMTM5CMTM519908-0.044-0.3180Yes
198C1QL1C1QL119916-0.044-0.3114Yes
199TMEM59LTMEM59L20054-0.045-0.3107Yes
200RUNDC3ARUNDC3A20069-0.045-0.3042Yes
201ATP6V1G2ATP6V1G220165-0.046-0.3013Yes
202BCANBCAN20254-0.048-0.2979Yes
203SNRPNSNRPN20423-0.050-0.2979Yes
204MAFMAF20468-0.051-0.2919Yes
205GRIA2GRIA220478-0.051-0.2843Yes
206PID1PID120654-0.054-0.2839Yes
207FBXL15FBXL1521042-0.064-0.2919Yes
208ALDOCALDOC21046-0.064-0.2819Yes
209OLIG2OLIG221293-0.075-0.2816Yes
210DLL1DLL121352-0.079-0.2718Yes
211ENHOENHO21382-0.082-0.2602Yes
212PHYHIPLPHYHIPL21383-0.082-0.2473Yes
213PCSK1NPCSK1N21396-0.083-0.2348Yes
214FXYD6FXYD621404-0.084-0.2219Yes
215SH3GL2SH3GL221419-0.085-0.2091Yes
216CRYABCRYAB21443-0.089-0.1961Yes
217SCG3SCG321484-0.096-0.1829Yes
218HEY2HEY221491-0.096-0.1680Yes
219KIF1AKIF1A21496-0.097-0.1528Yes
220DLL3DLL321526-0.105-0.1376Yes
221OLIG1OLIG121528-0.106-0.1209Yes
222NEU4NEU421549-0.115-0.1037Yes
223TTYH1TTYH121573-0.137-0.0831Yes
224TIMP4TIMP421580-0.147-0.0603Yes
225SOX8SOX821591-0.180-0.0323Yes
226ASCL1ASCL121596-0.206-0.0000Yes
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_PN_2006   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_PN_2006: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_PN_2006