DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetPHILLIPS_MES_2006
Enrichment Score (ES)0.41752848
Normalized Enrichment Score (NES)1.8970993
Nominal p-value0.0
FDR q-value3.0769233E-4
FWER p-Value0.001
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_MES_2006   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ITGA3ITGA3220.1160.0299Yes
2SPOCD1SPOCD1790.0930.0520Yes
3PMEPA1PMEPA1890.0910.0760Yes
4PLAUPLAU940.0900.0999Yes
5ITGA5ITGA52080.0770.1151Yes
6FGFRL1FGFRL12730.0720.1313Yes
7NCLNNCLN2820.0720.1501Yes
8FAM38AFAM38A3390.0680.1657Yes
9TWF1TWF14830.0620.1756Yes
10TNCTNC4880.0620.1920Yes
11FLNAFLNA4930.0620.2083Yes
12SGSHSGSH5540.0600.2215Yes
13OSMROSMR5800.0590.2361Yes
14GPR116GPR1166670.0570.2473Yes
15MVPMVP7110.0560.2603Yes
16SERPINE1SERPINE17250.0560.2746Yes
17SHROOM3SHROOM37970.0550.2859Yes
18LZTS1LZTS19540.0510.2923Yes
19TAGLNTAGLN9560.0510.3060Yes
20FLT1FLT110230.0500.3163Yes
21ACTN1ACTN112270.0470.3193Yes
22FAM20CFAM20C12510.0470.3307Yes
23COL4A2COL4A213970.0450.3359Yes
24NRP1NRP114140.0440.3470Yes
25FCGR2CFCGR2C14450.0440.3573Yes
26EMP1EMP115600.0430.3635Yes
27SBNO2SBNO217190.0410.3671Yes
28MYH9MYH917780.0410.3753Yes
29NRP2NRP218100.0400.3846Yes
30PI3PI319220.0390.3899Yes
31C22orf26C22orf2620350.0380.3949Yes
32PTRFPTRF22600.0360.3942Yes
33OSBPL3OSBPL327550.0330.3799Yes
34HSD3B7HSD3B727620.0330.3883Yes
35ITGA7ITGA729000.0320.3904Yes
36SLC16A3SLC16A329140.0320.3982Yes
37ICAM1ICAM129500.0310.4049Yes
38EFEMP2EFEMP230220.0310.4098Yes
39CECR2CECR231220.0300.4133Yes
40SLC39A8SLC39A832020.0300.4175Yes
41SALL4SALL436540.0270.4037No
42DEF6DEF636580.0270.4107No
43ANGPTL4ANGPTL439260.0250.4051No
44STEAP3STEAP339300.0250.4117No
45C1RC1R42140.0240.4049No
46CD151CD15142330.0240.4104No
47PVRL2PVRL245920.0220.3997No
48CHI3L1CHI3L147520.0210.3980No
49TRIM47TRIM4748210.0210.4004No
50SLC25A37SLC25A3748330.0210.4055No
51ECE1ECE151920.0190.3940No
52SLC12A9SLC12A957190.0170.3741No
53ZYXZYX58350.0170.3731No
54KLF16KLF1662910.0150.3559No
55FGGFGG63010.0150.3593No
56EHD2EHD263880.0140.3591No
57TTC38TTC3866730.0130.3494No
58MYL9MYL967870.0130.3476No
59PLAURPLAUR74770.0100.3183No
60LIFLIF75520.0100.3175No
61SOCS3SOCS375650.0100.3196No
62TRIM56TRIM5676150.0100.3200No
63LPAR1LPAR178760.0090.3103No
64PDLIM4PDLIM478950.0090.3118No
65MAP2K3MAP2K380230.0080.3082No
66GGNGGN80370.0080.3098No
67SHC1SHC180450.0080.3117No
68FESFES81430.0080.3093No
69FOSL2FOSL282540.0080.3063No
70FPR2FPR294520.0040.2515No
71EFNB2EFNB296810.0030.2417No
72RYR3RYR397300.0030.2403No
73FBN1FBN198200.0030.2368No
74BCL3BCL398520.0020.2360No
75ANPEPANPEP99080.0020.2340No
76HK3HK399710.0020.2317No
77S100A11S100A1110703-0.0000.1977No
78ANGPT2ANGPT210813-0.0010.1928No
79CA12CA1210917-0.0010.1882No
80PDGFAPDGFA11928-0.0040.1423No
81C1QTNF1C1QTNF111992-0.0040.1405No
82PDPNPDPN11998-0.0040.1414No
83RUNX1RUNX112042-0.0050.1406No
84UNC93B1UNC93B112108-0.0050.1389No
85VWA1VWA112201-0.0050.1359No
86MMP14MMP1412245-0.0050.1353No
87PDGFRLPDGFRL13079-0.0080.0986No
88DLC1DLC113283-0.0090.0915No
89METTL7BMETTL7B14209-0.0120.0515No
90PLA2G5PLA2G514303-0.0120.0504No
91CD97CD9714451-0.0130.0470No
92PDLIM7PDLIM714524-0.0130.0471No
93PAPPAPAPPA14536-0.0130.0500No
94TPP1TPP114556-0.0130.0526No
95TRABDTRABD14647-0.0130.0520No
96TNFRSF10DTNFRSF10D14712-0.0140.0527No
97HOMER3HOMER314990-0.0150.0438No
98SLC22A18SLC22A1815179-0.0160.0392No
99CD248CD24815184-0.0160.0431No
100HRH1HRH115226-0.0160.0454No
101JUNBJUNB15319-0.0160.0454No
102BACE2BACE215352-0.0160.0483No
103C15orf52C15orf5215366-0.0160.0520No
104SERPINH1SERPINH115559-0.0170.0476No
105RAB34RAB3415944-0.0190.0347No
106COL4A1COL4A116019-0.0190.0364No
107TIMP1TIMP116033-0.0190.0409No
108SERPINA1SERPINA116362-0.0210.0312No
109C1RLC1RL16390-0.0210.0355No
110EMP3EMP316399-0.0210.0406No
111EPAS1EPAS116865-0.0230.0251No
112LRRC32LRRC3218378-0.031-0.0369No
113NEURL2NEURL219294-0.038-0.0694No
114IL32IL3219484-0.039-0.0677No
115THBDTHBD19532-0.040-0.0593No
116RRBP1RRBP119589-0.040-0.0512No
117LRRC29LRRC2920012-0.045-0.0589No
118PARP10PARP1020078-0.045-0.0498No
119ESM1ESM120127-0.046-0.0398No
120ACTA2ACTA220255-0.048-0.0330No
121RRASRRAS20323-0.049-0.0232No
122RHOJRHOJ20420-0.050-0.0143No
123PLEKHF1PLEKHF121123-0.067-0.0290No
124IFITM2IFITM221470-0.093-0.0203No
125IFITM3IFITM321498-0.0980.0046No
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_MES_2006   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_MES_2006: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_MES_2006