DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetFOSL1_REGULON
Enrichment Score (ES)0.43442577
Normalized Enrichment Score (NES)2.13733
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: FOSL1_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GFPT2GFPT240.1410.0212Yes
2SLC4A7SLC4A780.1320.0411Yes
3ITGA3ITGA3220.1160.0580Yes
4AHNAK2AHNAK2250.1140.0752Yes
5SEMA4FSEMA4F590.0980.0885Yes
6COL6A2COL6A2920.0910.1007Yes
7PLAUPLAU940.0900.1144Yes
8RIN1RIN11250.0860.1259Yes
9CD44CD441410.0840.1379Yes
10TRAM2TRAM21420.0840.1506Yes
11LPPLPP1440.0830.1632Yes
12ESYT1ESYT11560.0820.1752Yes
13ACTN4ACTN41740.0800.1865Yes
14ITGA5ITGA52080.0770.1966Yes
15MYOFMYOF2450.0740.2062Yes
16COL18A1COL18A12630.0730.2164Yes
17PYGBPYGB3080.0700.2249Yes
18KLHL21KLHL213240.0690.2347Yes
19AXLAXL3660.0670.2430Yes
20IQGAP1IQGAP13780.0670.2526Yes
21FLNAFLNA4930.0620.2566Yes
22DCBLD2DCBLD24940.0620.2660Yes
23METMET5200.0610.2740Yes
24CDC42EP3CDC42EP35760.0590.2804Yes
25QSOX1QSOX15820.0590.2892Yes
26CRIM1CRIM16150.0580.2965Yes
27SLC35C1SLC35C16390.0580.3042Yes
28MYLKMYLK6540.0570.3122Yes
29VCLVCL6740.0570.3199Yes
30SYNJ2SYNJ27030.0560.3271Yes
31MVPMVP7110.0560.3353Yes
32SH2B3SH2B37240.0560.3432Yes
33SERPINE1SERPINE17250.0560.3517Yes
34CAV1CAV18140.0540.3558Yes
35B3GNT2B3GNT28980.0530.3599Yes
36CRTAMCRTAM10950.0490.3581Yes
37PARVAPARVA10970.0490.3655Yes
38ANXA2ANXA211460.0480.3706Yes
39PTGER4PTGER412070.0470.3749Yes
40ACTN1ACTN112270.0470.3811Yes
41PMAIP1PMAIP112840.0460.3855Yes
42IL11IL1113290.0460.3903Yes
43GEMGEM14030.0450.3937Yes
44CUL7CUL714410.0440.3986Yes
45DSTNDSTN14460.0440.4051Yes
46FHL2FHL214930.0430.4096Yes
47EMP1EMP115600.0430.4130Yes
48ABCD1ABCD115730.0430.4189Yes
49TAPBPTAPBP15780.0430.4252Yes
50FBRSFBRS15790.0430.4316Yes
51MYH9MYH917780.0410.4285Yes
52WDR1WDR118850.0400.4296Yes
53TCF4TCF419500.0390.4325Yes
54EDEM1EDEM120340.0380.4344Yes
55PTHLHPTHLH23070.0360.4272No
56ANXA2P3ANXA2P323360.0360.4313No
57EPHA2EPHA226040.0340.4239No
58SRPX2SRPX228510.0320.4172No
59CSRP1CSRP132330.0290.4039No
60MYD88MYD8832940.0290.4055No
61TMEM214TMEM21433210.0290.4086No
62ZMYM4ZMYM433750.0290.4105No
63SMAGPSMAGP34140.0280.4130No
64FYCO1FYCO138690.0260.3957No
65CASTCAST38940.0260.3984No
66CLIP4CLIP439360.0250.4003No
67GBE1GBE139830.0250.4020No
68ZBTB38ZBTB3840760.0250.4014No
69DLX2DLX241320.0240.4025No
70ADORA2BADORA2B41960.0240.4032No
71KCND1KCND142820.0240.4028No
72G6PDG6PD42940.0240.4059No
73PLCB1PLCB143370.0230.4075No
74ECM1ECM143900.0230.4085No
75PRNPPRNP46410.0220.4002No
76SH2D4ASH2D4A47760.0210.3971No
77CAPN2CAPN247950.0210.3995No
78LGALS8LGALS849270.0210.3965No
79ANXA1ANXA152930.0190.3823No
80FADS3FADS353350.0190.3832No
81PXNPXN53590.0190.3850No
82IFRD2IFRD255460.0180.3789No
83DRAM1DRAM155930.0180.3795No
84GLIPR1GLIPR156050.0170.3816No
85GLRXGLRX56150.0170.3838No
86ITGA6ITGA656790.0170.3835No
87LMNALMNA59190.0160.3748No
88OLFML2BOLFML2B59390.0160.3763No
89MGAT1MGAT160970.0150.3713No
90APOBEC3BAPOBEC3B61190.0150.3727No
91ADSSADSS61530.0150.3734No
92MGAT4BMGAT4B61610.0150.3754No
93ARPC1BARPC1B61920.0150.3763No
94EXOC3EXOC362620.0150.3753No
95PERPPERP62650.0150.3775No
96ANXA11ANXA1162700.0150.3795No
97VASPVASP64610.0140.3727No
98MICAL2MICAL265130.0140.3724No
99RHBDF2RHBDF267210.0130.3647No
100KCNAB2KCNAB267750.0130.3642No
101ATP1A1ATP1A170340.0120.3539No
102P4HA2P4HA270580.0120.3546No
103ANXA2P2ANXA2P271740.0110.3510No
104CXXC4CXXC473550.0110.3442No
105KCNN4KCNN473690.0110.3452No
106CAV2CAV274290.0100.3440No
107CYBRD1CYBRD174420.0100.3450No
108PLAURPLAUR74770.0100.3450No
109LIFLIF75520.0100.3431No
110KCND2KCND276670.0100.3392No
111SSH3SSH379390.0090.3279No
112IL13RA1IL13RA180330.0080.3248No
113SHC1SHC180450.0080.3255No
114CD46CD4681060.0080.3240No
115BAG3BAG381510.0080.3231No
116FOSL2FOSL282540.0080.3195No
117PLP2PLP283800.0070.3148No
118NT5ENT5E84190.0070.3141No
119PARVBPARVB84700.0070.3128No
120CDKN1BCDKN1B84920.0070.3129No
121BFSP1BFSP185390.0070.3118No
122IER3IER386020.0070.3099No
123MAN1A1MAN1A187270.0060.3050No
124GLT8D2GLT8D288410.0060.3006No
125S100A6S100A690020.0050.2939No
126BET1LBET1L92000.0050.2854No
127UPP1UPP193120.0040.2808No
128RHOGRHOG95780.0030.2690No
129IL18R1IL18R198650.0020.2559No
130ANPEPANPEP99080.0020.2543No
131CHD7CHD799740.0020.2516No
132DEGS1DEGS199850.0020.2514No
133MOCOSMOCOS100490.0020.2488No
134RNH1RNH1100780.0020.2477No
135DNAJC10DNAJC10105500.0000.2257No
136MT2AMT2A105780.0000.2245No
137ANP32AANP32A106160.0000.2228No
138TNFRSF12ATNFRSF12A106500.0000.2213No
139S100A11S100A1110703-0.0000.2188No
140RNFT2RNFT210803-0.0000.2143No
141TXNTXN10958-0.0010.2072No
142CBX7CBX710970-0.0010.2069No
143LGALS1LGALS111128-0.0010.1997No
144S100A10S100A1011216-0.0020.1959No
145TMED9TMED911408-0.0020.1874No
146FUT9FUT911437-0.0030.1864No
147CLIC1CLIC111509-0.0030.1835No
148RAVER2RAVER211529-0.0030.1831No
149SQSTM1SQSTM111598-0.0030.1804No
150PNPLA2PNPLA211791-0.0040.1719No
151ADRM1ADRM111859-0.0040.1694No
152AKR1C3AKR1C311866-0.0040.1697No
153AHNAKAHNAK11869-0.0040.1702No
154PARP12PARP1211918-0.0040.1686No
155ATOX1ATOX111943-0.0040.1681No
156PIGTPIGT12052-0.0050.1637No
157PRSS23PRSS2312359-0.0060.1503No
158TSPAN7TSPAN712707-0.0070.1351No
159TPD52L2TPD52L212877-0.0070.1283No
160DRAP1DRAP113004-0.0080.1235No
161FLIIFLII13261-0.0090.1128No
162S100A13S100A1313428-0.0090.1065No
163SERPINB6SERPINB613572-0.0100.1012No
164TSPAN1TSPAN113721-0.0100.0958No
165MAP2MAP214012-0.0110.0839No
166PROCRPROCR14056-0.0110.0836No
167ARFRP1ARFRP114333-0.0120.0726No
168ANXA4ANXA414631-0.0130.0607No
169SLC38A10SLC38A1014660-0.0140.0614No
170MCFD2MCFD214723-0.0140.0606No
171SDC4SDC414948-0.0150.0524No
172FURINFURIN15012-0.0150.0517No
173FAHFAH15132-0.0150.0484No
174HSPA5HSPA515169-0.0150.0491No
175TPM2TPM215346-0.0160.0433No
176BACE2BACE215352-0.0160.0455No
177STC1STC115355-0.0160.0479No
178WIPI1WIPI115356-0.0160.0503No
179TIMP1TIMP116033-0.0190.0216No
180CYB561CYB56116073-0.0190.0227No
181IMPAD1IMPAD116242-0.0200.0179No
182PQLC3PQLC316257-0.0200.0204No
183EMP3EMP316399-0.0210.0169No
184LRRFIP2LRRFIP216442-0.0210.0181No
185RPS6KA4RPS6KA416531-0.0220.0173No
186MARCKSL1MARCKSL116590-0.0220.0179No
187TNFRSF10BTNFRSF10B16697-0.0220.0163No
188NSMAFNSMAF17159-0.024-0.0016No
189FOXN3FOXN317248-0.025-0.0019No
190MAFGMAFG17346-0.025-0.0026No
191MT1GMT1G17375-0.026-0.0000No
192FADDFADD17454-0.0260.0002No
193PHLDA2PHLDA217461-0.0260.0039No
194VDRVDR17575-0.0270.0027No
195COQ10BCOQ10B17692-0.0270.0014No
196ARSAARSA18134-0.030-0.0147No
197MAST1MAST118212-0.030-0.0137No
198SERINC3SERINC318410-0.032-0.0181No
199FOXC1FOXC118488-0.032-0.0168No
200RELBRELB18625-0.033-0.0182No
201YIPF3YIPF318888-0.035-0.0252No
202TMEM109TMEM10918922-0.035-0.0214No
203TFPI2TFPI219324-0.038-0.0344No
204GSDMDGSDMD19445-0.039-0.0341No
205ETHE1ETHE119464-0.039-0.0291No
206RRBP1RRBP119589-0.040-0.0288No
207MYO1CMYO1C19667-0.041-0.0262No
208SLC10A3SLC10A319679-0.041-0.0205No
209WDR55WDR5519807-0.042-0.0200No
210REXO2REXO220431-0.050-0.0415No
211CTNND2CTNND220977-0.062-0.0576No
212SH3BGRL3SH3BGRL320978-0.062-0.0482No
213KDELR3KDELR320996-0.063-0.0395No
214RAC2RAC221019-0.063-0.0309No
215RBKSRBKS21065-0.065-0.0232No
216PLEKHF1PLEKHF121123-0.067-0.0157No
217YIF1AYIF1A21214-0.071-0.0092No
218CEBPBCEBPB21428-0.086-0.0060No
219GSTA4GSTA421457-0.0910.0065No
Table: GSEA details [plain text format]



Fig 2: FOSL1_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FOSL1_REGULON: Random ES distribution   
Gene set null distribution of ES for FOSL1_REGULON