DatasetshNF1_exprs.shNF1_phenotype.cls
#shNF1_versus_shCtrl.shNF1_phenotype.cls
#shNF1_versus_shCtrl_repos
PhenotypeshNF1_phenotype.cls#shNF1_versus_shCtrl_repos
Upregulated in classshNF1
GeneSetBNC2_REGULON
Enrichment Score (ES)0.39187753
Normalized Enrichment Score (NES)1.7351049
Nominal p-value0.0
FDR q-value0.0015367322
FWER p-Value0.009
Table: GSEA Results Summary



Fig 1: Enrichment plot: BNC2_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1THBS1THBS1130.1230.0323Yes
2TGFBR2TGFBR2800.0930.0541Yes
3RGS4RGS4880.0920.0782Yes
4COL6A2COL6A2920.0910.1023Yes
5B4GALT1B4GALT11550.0830.1214Yes
6COL1A1COL1A11580.0820.1432Yes
7EDIL3EDIL31690.0800.1642Yes
8MYOFMYOF2450.0740.1806Yes
9PPLPPL2590.0730.1995Yes
10MDFICMDFIC2710.0720.2183Yes
11ADAMTS1ADAMTS13490.0680.2328Yes
12METMET5200.0610.2411Yes
13COL1A2COL1A26510.0570.2503Yes
14CAV1CAV18140.0540.2573Yes
15WNT5AWNT5A8920.0530.2678Yes
16COL6A3COL6A39610.0510.2783Yes
17COL21A1COL21A19710.0510.2915Yes
18CPA4CPA410660.0500.3003Yes
19CCDC88CCCDC88C10810.0490.3128Yes
20GCNT1GCNT110930.0490.3254Yes
21ANXA2ANXA211460.0480.3359Yes
22PTGER4PTGER412070.0470.3457Yes
23MBNL2MBNL213100.0460.3531Yes
24LOXLOX13910.0450.3613Yes
25GEMGEM14030.0450.3727Yes
26SLC14A1SLC14A115010.0430.3798Yes
27DPYDDPYD17040.0410.3814Yes
28ALDH1A1ALDH1A117170.0410.3919Yes
29MCTP2MCTP220440.0380.3869No
30ARHGAP10ARHGAP1022170.0370.3887No
31SEMA3CSEMA3C28630.0320.3672No
32MLPHMLPH29820.0310.3700No
33ACPPACPP30840.0300.3734No
34ITGA1ITGA131590.0300.3780No
35AMIGO2AMIGO231940.0300.3843No
36OLFML2AOLFML2A32280.0300.3907No
37CNN1CNN134960.0280.3857No
38CASTCAST38940.0260.3740No
39GBE1GBE139830.0250.3766No
40CLEC2BCLEC2B41450.0240.3756No
41AQP1AQP142790.0240.3757No
42TSPAN9TSPAN946700.0220.3634No
43TGFBITGFBI47920.0210.3634No
44PNPLA4PNPLA449290.0210.3626No
45CNN2CNN250910.0200.3604No
46ANXA1ANXA152930.0190.3561No
47PHACTR1PHACTR158090.0170.3365No
48ASB13ASB1358840.0160.3375No
49ARPC1BARPC1B61920.0150.3272No
50RAB27ARAB27A62040.0150.3307No
51ABLIM3ABLIM364250.0140.3242No
52P4HA2P4HA270580.0120.2980No
53SYNCSYNC72430.0110.2924No
54CAV2CAV274290.0100.2866No
55ACVR1ACVR174520.0100.2883No
56PLAURPLAUR74770.0100.2900No
57CYP1B1CYP1B176730.0100.2835No
58ANXA5ANXA579340.0090.2737No
59BST1BST181200.0080.2673No
60STAT4STAT481350.0080.2688No
61MICBMICB83470.0070.2610No
62HBP1HBP184930.0070.2561No
63PYCARDPYCARD87490.0060.2458No
64GLT8D2GLT8D288410.0060.2432No
65TRPV2TRPV290620.0050.2343No
66ABCA3ABCA391890.0050.2296No
67SGCESGCE95930.0030.2118No
68HLA-DPB1HLA-DPB196720.0030.2090No
69TGOLN2TGOLN299310.0020.1975No
70CHD7CHD799740.0020.1961No
71DCNDCN101790.0010.1870No
72MAPK9MAPK9104040.0010.1768No
73RNFT2RNFT210803-0.0000.1584No
74PTGS2PTGS211356-0.0020.1333No
75PTPRRPTPRR11434-0.0020.1304No
76CLCA2CLCA211500-0.0030.1281No
77ARHGDIGARHGDIG11589-0.0030.1248No
78AHNAKAHNAK11869-0.0040.1129No
79PIK3CDPIK3CD11950-0.0040.1103No
80CAMSAP1CAMSAP112633-0.0060.0803No
81PSD4PSD413124-0.0080.0596No
82WIF1WIF113310-0.0090.0533No
83PAMPAM13468-0.0090.0485No
84PLA2R1PLA2R113994-0.0110.0270No
85PROCRPROCR14056-0.0110.0271No
86COL5A3COL5A315453-0.017-0.0334No
87MARK1MARK116034-0.019-0.0552No
88COL3A1COL3A116349-0.021-0.0643No
89CH25HCH25H16756-0.023-0.0772No
90CKBCKB17020-0.024-0.0831No
91PCCBPCCB17478-0.026-0.0974No
92SEC61A2SEC61A217540-0.026-0.0932No
93HLA-DOAHLA-DOA17607-0.027-0.0891No
94LUMLUM18137-0.030-0.1057No
95ENPP1ENPP118657-0.033-0.1210No
96SALL2SALL218895-0.035-0.1228No
97COPZ2COPZ219095-0.036-0.1224No
98GSDMDGSDMD19445-0.039-0.1282No
99IL1R1IL1R119546-0.040-0.1222No
100ZNF75DZNF75D19598-0.040-0.1139No
101MYO1CMYO1C19667-0.041-0.1061No
102SLC10A3SLC10A319679-0.041-0.0957No
103COL10A1COL10A120176-0.047-0.1063No
104CTNND2CTNND220977-0.062-0.1270No
105OLIG2OLIG221293-0.075-0.1217No
106TPD52L1TPD52L121385-0.082-0.1041No
107CSPG5CSPG521531-0.108-0.0820No
108TTYH1TTYH121573-0.137-0.0473No
109C1orf61C1orf6121592-0.1810.0002No
Table: GSEA details [plain text format]



Fig 2: BNC2_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BNC2_REGULON: Random ES distribution   
Gene set null distribution of ES for BNC2_REGULON