Details for gene set VERHAAK_PN

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	GRD
GeneSet	VERHAAK_PN_2010
Enrichment Score (ES)	0.42768008
Normalized Enrichment Score (NES)	1.9229542
Nominal p-value	0.0
FDR q-value	0.0011165414
FWER p-Value	0.002

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GRIA2	GRIA2	27	0.178	0.0333	Yes
2	CLASP2	CLASP2	34	0.171	0.0661	Yes
3	MAP2	MAP2	145	0.108	0.0820	Yes
4	SEZ6L	SEZ6L	228	0.096	0.0968	Yes
5	TMCC1	TMCC1	264	0.093	0.1131	Yes
6	SRGAP3	SRGAP3	327	0.088	0.1272	Yes
7	MTSS1	MTSS1	362	0.085	0.1421	Yes
8	SNX26	SNX26	373	0.084	0.1579	Yes
9	NCALD	NCALD	403	0.082	0.1724	Yes
10	NCAM1	NCAM1	549	0.075	0.1803	Yes
11	ZNF286A	ZNF286A	668	0.071	0.1884	Yes
12	ABAT	ABAT	806	0.066	0.1947	Yes
13	FXYD6	FXYD6	892	0.063	0.2030	Yes
14	PPM1D	PPM1D	995	0.061	0.2100	Yes
15	CBX1	CBX1	1000	0.060	0.2215	Yes
16	RALGPS1	RALGPS1	1050	0.060	0.2307	Yes
17	CDKN1B	CDKN1B	1088	0.059	0.2404	Yes
18	PLCB4	PLCB4	1109	0.058	0.2508	Yes
19	MYB	MYB	1166	0.057	0.2593	Yes
20	FAM125B	FAM125B	1173	0.057	0.2701	Yes
21	ZNF184	ZNF184	1217	0.056	0.2789	Yes
22	STMN1	STMN1	1330	0.054	0.2841	Yes
23	SATB1	SATB1	1348	0.054	0.2937	Yes
24	DPYSL4	DPYSL4	1368	0.053	0.3031	Yes
25	NLGN3	NLGN3	1376	0.053	0.3130	Yes
26	TOP2B	TOP2B	1403	0.053	0.3220	Yes
27	MARCKSL1	MARCKSL1	1500	0.051	0.3274	Yes
28	STMN4	STMN4	1560	0.050	0.3344	Yes
29	TTYH1	TTYH1	1643	0.049	0.3401	Yes
30	MATR3	MATR3	1662	0.049	0.3488	Yes
31	ATP1A3	ATP1A3	1678	0.049	0.3575	Yes
32	DBN1	DBN1	1852	0.046	0.3584	Yes
33	ARHGEF9	ARHGEF9	1905	0.046	0.3649	Yes
34	HN1	HN1	1966	0.045	0.3708	Yes
35	MARCKS	MARCKS	2032	0.044	0.3763	Yes
36	TAF5	TAF5	2071	0.044	0.3831	Yes
37	SOX10	SOX10	2218	0.042	0.3844	Yes
38	RAB33A	RAB33A	2265	0.042	0.3903	Yes
39	NRXN2	NRXN2	2272	0.042	0.3981	Yes
40	BCOR	BCOR	2426	0.040	0.3987	Yes
41	SEC61A2	SEC61A2	2469	0.040	0.4044	Yes
42	SCG3	SCG3	2487	0.039	0.4112	Yes
43	MAST1	MAST1	2578	0.039	0.4145	Yes
44	KLRK1	KLRK1	2943	0.036	0.4044	Yes
45	MYT1	MYT1	3053	0.035	0.4061	Yes
46	C6orf134	C6orf134	3169	0.034	0.4073	Yes
47	C1QL1	C1QL1	3268	0.033	0.4092	Yes
48	FLRT1	FLRT1	3282	0.033	0.4150	Yes
49	LPHN3	LPHN3	3346	0.033	0.4183	Yes
50	TMEFF1	TMEFF1	3356	0.033	0.4242	Yes
51	DUSP26	DUSP26	3426	0.032	0.4272	Yes
52	ALCAM	ALCAM	3548	0.031	0.4276	Yes
53	WASF1	WASF1	3673	0.030	0.4277	Yes
54	CDK5R1	CDK5R1	4054	0.028	0.4153	No
55	CSPG5	CSPG5	4138	0.027	0.4168	No
56	TOPBP1	TOPBP1	4266	0.027	0.4160	No
57	BCL7A	BCL7A	4293	0.026	0.4199	No
58	SLCO5A1	SLCO5A1	4568	0.025	0.4119	No
59	PFN2	PFN2	4694	0.024	0.4108	No
60	CRMP1	CRMP1	4989	0.023	0.4014	No
61	C1orf106	C1orf106	5333	0.021	0.3894	No
62	BCAN	BCAN	5383	0.021	0.3911	No
63	VEZF1	VEZF1	5451	0.020	0.3919	No
64	ACTR1A	ACTR1A	5470	0.020	0.3950	No
65	PCDH11Y	PCDH11Y	5599	0.020	0.3928	No
66	PDE10A	PDE10A	5744	0.019	0.3898	No
67	SOX11	SOX11	5768	0.019	0.3923	No
68	MMP15	MMP15	5862	0.018	0.3915	No
69	RAP2A	RAP2A	5913	0.018	0.3927	No
70	CHD7	CHD7	6015	0.018	0.3914	No
71	CRB1	CRB1	6017	0.018	0.3948	No
72	ZEB2	ZEB2	6101	0.017	0.3943	No
73	MMP16	MMP16	6212	0.017	0.3924	No
74	DPF1	DPF1	6416	0.016	0.3860	No
75	CSNK1E	CSNK1E	6457	0.016	0.3872	No
76	PAFAH1B3	PAFAH1B3	6681	0.015	0.3796	No
77	TSPAN3	TSPAN3	6907	0.014	0.3718	No
78	SOX2	SOX2	6993	0.013	0.3704	No
79	CASK	CASK	7134	0.013	0.3664	No
80	YPEL1	YPEL1	7294	0.012	0.3614	No
81	GPR17	GPR17	7361	0.012	0.3606	No
82	ZNF711	ZNF711	7592	0.011	0.3520	No
83	PELI1	PELI1	7614	0.011	0.3532	No
84	GPM6A	GPM6A	7717	0.011	0.3505	No
85	EPB41	EPB41	7892	0.010	0.3444	No
86	AMOTL2	AMOTL2	7900	0.010	0.3460	No
87	AOF2	AOF2	8005	0.010	0.3430	No
88	MLLT11	MLLT11	8092	0.009	0.3408	No
89	TTC3	TTC3	8101	0.009	0.3422	No
90	KLRC4	KLRC4	8265	0.009	0.3362	No
91	GNG4	GNG4	8384	0.008	0.3323	No
92	CDC7	CDC7	8577	0.008	0.3248	No
93	P2RX7	P2RX7	8606	0.007	0.3249	No
94	VAX2	VAX2	8641	0.007	0.3248	No
95	SCN3A	SCN3A	8713	0.007	0.3228	No
96	MYST2	MYST2	9183	0.005	0.3020	No
97	PODXL2	PODXL2	9226	0.005	0.3010	No
98	LRP6	LRP6	9312	0.005	0.2980	No
99	GRID2	GRID2	9539	0.004	0.2882	No
100	GADD45G	GADD45G	9799	0.003	0.2767	No
101	NOL4	NOL4	9805	0.003	0.2770	No
102	ASCL1	ASCL1	10271	0.001	0.2556	No
103	EPHB1	EPHB1	10273	0.001	0.2558	No
104	ZNF643	ZNF643	10518	0.001	0.2445	No
105	HRASLS	HRASLS	10626	0.000	0.2395	No
106	BAI3	BAI3	10928	-0.001	0.2256	No
107	MAPT	MAPT	11069	-0.001	0.2194	No
108	ATAD5	ATAD5	11274	-0.002	0.2102	No
109	HOXD3	HOXD3	11340	-0.002	0.2077	No
110	FGF9	FGF9	11403	-0.003	0.2053	No
111	ERBB3	ERBB3	11564	-0.003	0.1984	No
112	RUFY3	RUFY3	11730	-0.004	0.1915	No
113	IL1RAPL1	IL1RAPL1	11783	-0.004	0.1898	No
114	SORCS3	SORCS3	12038	-0.005	0.1788	No
115	DPP6	DPP6	12045	-0.005	0.1795	No
116	TMEM35	TMEM35	12134	-0.005	0.1764	No
117	BEX1	BEX1	12138	-0.005	0.1772	No
118	C1orf61	C1orf61	12173	-0.005	0.1767	No
119	DCX	DCX	12388	-0.006	0.1678	No
120	CXXC4	CXXC4	12495	-0.006	0.1641	No
121	PHF16	PHF16	12818	-0.008	0.1506	No
122	GABRA3	GABRA3	12970	-0.008	0.1451	No
123	RALGPS2	RALGPS2	13046	-0.008	0.1432	No
124	PURG	PURG	13098	-0.009	0.1425	No
125	KLRC3	KLRC3	13100	-0.009	0.1441	No
126	CLGN	CLGN	13156	-0.009	0.1433	No
127	PCDH11X	PCDH11X	13392	-0.010	0.1342	No
128	SOX4	SOX4	13444	-0.010	0.1337	No
129	TOX3	TOX3	13571	-0.010	0.1298	No
130	CA10	CA10	13883	-0.012	0.1176	No
131	ZNF510	ZNF510	14252	-0.013	0.1029	No
132	ZNF248	ZNF248	14416	-0.014	0.0979	No
133	HMGB3	HMGB3	14419	-0.014	0.1005	No
134	RBPJ	RBPJ	14462	-0.014	0.1012	No
135	RAD21	RAD21	14563	-0.014	0.0993	No
136	DLL3	DLL3	14605	-0.014	0.1002	No
137	TMEM118	TMEM118	14809	-0.015	0.0936	No
138	CKB	CKB	15032	-0.016	0.0864	No
139	HDAC2	HDAC2	15049	-0.016	0.0888	No
140	NR0B1	NR0B1	15070	-0.016	0.0911	No
141	KIF21B	KIF21B	15568	-0.018	0.0714	No
142	NRXN1	NRXN1	16554	-0.023	0.0299	No
143	PPM1E	PPM1E	16778	-0.024	0.0242	No
144	FHOD3	FHOD3	17073	-0.026	0.0155	No
145	GSTA4	GSTA4	17184	-0.026	0.0154	No
146	REEP1	REEP1	17553	-0.028	0.0037	No
147	CAMSAP1L1	CAMSAP1L1	17874	-0.030	-0.0054	No
148	CNTN1	CNTN1	17931	-0.031	-0.0021	No
149	ICK	ICK	18209	-0.032	-0.0087	No
150	PAK7	PAK7	18244	-0.033	-0.0040	No
151	MYO10	MYO10	18482	-0.034	-0.0084	No
152	MCM10	MCM10	18493	-0.035	-0.0022	No
153	DGKI	DGKI	18589	-0.035	0.0002	No
154	SPTBN2	SPTBN2	18605	-0.035	0.0063	No
155	FBXO21	FBXO21	18650	-0.036	0.0111	No
156	WDR68	WDR68	18813	-0.037	0.0107	No
157	PAK3	PAK3	18892	-0.038	0.0144	No
158	DNM3	DNM3	19167	-0.040	0.0094	No
159	E2F3	E2F3	19227	-0.041	0.0146	No
160	MPPED2	MPPED2	19357	-0.042	0.0167	No
161	SLC1A1	SLC1A1	19759	-0.047	0.0070	No
162	OLIG2	OLIG2	19896	-0.049	0.0100	No
163	CDC25A	CDC25A	19936	-0.049	0.0177	No
164	TNRC4	TNRC4	20276	-0.054	0.0124	No
165	LRRTM4	LRRTM4	20562	-0.060	0.0106	No
166	ZNF804A	ZNF804A	20595	-0.060	0.0208	No
167	GSK3B	GSK3B	20757	-0.065	0.0258	No
168	FAM110B	FAM110B	20872	-0.068	0.0337	No