DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetVERHAAK_NEU_2010
Enrichment Score (ES)-0.18673901
Normalized Enrichment Score (NES)-0.8068953
Nominal p-value0.89
FDR q-value0.8753801
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_NEU_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CHN1CHN11190.1160.0286No
2TSNAXTSNAX3410.0870.0437No
3FHITFHIT4570.0800.0619No
4TCEAL1TCEAL14630.0800.0850No
5SCHIP1SCHIP19010.0630.0831No
6MORF4L2MORF4L212120.0560.0851No
7CRBNCRBN12210.0560.1012No
8KCNJ3KCNJ318320.0470.0865No
9PPP1R1APPP1R1A20090.0450.0914No
10FBXO3FBXO320570.0440.1022No
11BASP1BASP123650.0400.0998No
12TPM3TPM324940.0390.1054No
13PPFIA2PPFIA229580.0360.0943No
14PARP8PARP830290.0350.1014No
15ADD3ADD333920.0320.0940No
16NSL1NSL134590.0320.1003No
17PGBD5PGBD535130.0310.1070No
18PEX11BPEX11B38290.0290.1009No
19ATP5F1ATP5F141990.0270.0917No
20TTPATTPA43370.0260.0930No
21CRYMCRYM43690.0260.0992No
22VSX1VSX144640.0250.1023No
23TMEM144TMEM14446560.0240.1006No
24SNCGSNCG47690.0240.1023No
25MGST3MGST348810.0230.1039No
26GABARAPL2GABARAPL250640.0220.1019No
27RND1RND152190.0210.1011No
28CRYZL1CRYZL152440.0210.1062No
29EPB41L3EPB41L352970.0210.1100No
30TTC1TTC159850.0180.0832No
31SIRT5SIRT560640.0170.0847No
32CDR1CDR160650.0170.0898No
33AGXT2L1AGXT2L161960.0170.0887No
34PRPSAP2PRPSAP262070.0170.0932No
35FUT9FUT962980.0160.0938No
36AGTPBP1AGTPBP163790.0160.0948No
37ANXA7ANXA764130.0160.0980No
38GNAI1GNAI165520.0150.0961No
39MGC72080MGC7208067590.0140.0907No
40CAMK2GCAMK2G68620.0140.0901No
41PPA1PPA168870.0140.0931No
42CA4CA468910.0140.0970No
43EDIL3EDIL369600.0140.0978No
44KCNK1KCNK170340.0130.0983No
45MAT2BMAT2B71150.0130.0984No
46SNX11SNX1173030.0120.0933No
47IMPA1IMPA173270.0120.0958No
48CCDC121CCDC12173690.0120.0974No
49SAR1ASAR1A74300.0120.0981No
50USP33USP3376770.0110.0898No
51CDC42CDC4277060.0110.0917No
52ORC4LORC4L79930.0100.0812No
53NDUFS3NDUFS380030.0100.0836No
54FXYD1FXYD181460.0090.0797No
55CALM2CALM282180.0090.0789No
56ENPP4ENPP486340.0070.0618No
57GUK1GUK186460.0070.0634No
58HPCAL4HPCAL487640.0070.0599No
59HPCAHPCA94760.0040.0281No
60REPS2REPS296070.0040.0231No
61PPP2R5APPP2R5A98410.0030.0131No
62SEPW1SEPW1103780.001-0.0116No
63NANOS1NANOS1106310.000-0.0233No
64MAGEH1MAGEH1106330.000-0.0233No
65BCAS1BCAS1106620.000-0.0247No
66CUTCCUTC10699-0.000-0.0263No
67MMDMMD11165-0.002-0.0474No
68SEPP1SEPP111451-0.003-0.0599No
69MDH1MDH111609-0.003-0.0662No
70SLCO1A2SLCO1A211966-0.005-0.0815No
71CASQ1CASQ112231-0.005-0.0922No
72PEX19PEX1912748-0.007-0.1141No
73EVI2AEVI2A12796-0.007-0.1141No
74SLC30A10SLC30A1013514-0.010-0.1445No
75MBPMBP13559-0.010-0.1435No
76MYBPC1MYBPC113750-0.011-0.1491No
77GPR22GPR2213807-0.011-0.1484No
78FAM49BFAM49B13875-0.012-0.1482No
79ATP5LATP5L14017-0.012-0.1512No
80GABRB2GABRB214212-0.013-0.1564No
81AKR7A3AKR7A314423-0.014-0.1622No
82COX5BCOX5B14494-0.014-0.1614No
83ATRNL1ATRNL115040-0.016-0.1820Yes
84GRM1GRM115067-0.016-0.1784Yes
85GRM3GRM315106-0.017-0.1753Yes
86NDRG2NDRG215120-0.017-0.1710Yes
87ENPP2ENPP215253-0.017-0.1721Yes
88SGK3SGK315307-0.017-0.1695Yes
89CPNE6CPNE615408-0.018-0.1690Yes
90TCEAL2TCEAL215517-0.018-0.1686Yes
91UGT8UGT815565-0.018-0.1654Yes
92PSCD1PSCD115634-0.019-0.1631Yes
93DHRS9DHRS915701-0.019-0.1605Yes
94ANXA3ANXA315751-0.019-0.1571Yes
95SH3GL3SH3GL315758-0.019-0.1517Yes
96VIPVIP15786-0.019-0.1473Yes
97DYNC1I1DYNC1I116423-0.022-0.1703Yes
98PLCL1PLCL116734-0.024-0.1777Yes
99ACSL4ACSL416737-0.024-0.1708Yes
100LYRM1LYRM116811-0.024-0.1670Yes
101THTPATHTPA17061-0.026-0.1711Yes
102BEST1BEST117159-0.026-0.1679Yes
103NTSR2NTSR217219-0.027-0.1629Yes
104CLCA4CLCA417277-0.027-0.1577Yes
105EDG1EDG117474-0.028-0.1586Yes
106ARRB1ARRB117728-0.029-0.1618Yes
107PDE6DPDE6D17843-0.030-0.1583Yes
108UROSUROS17887-0.030-0.1514Yes
109KIAA1598KIAA159817974-0.031-0.1464Yes
110ANKRD46ANKRD4618519-0.035-0.1615Yes
111ROGDIROGDI18649-0.036-0.1571Yes
112SH3GL2SH3GL218995-0.039-0.1618Yes
113CCKCCK19492-0.043-0.1721Yes
114YPEL5YPEL519594-0.045-0.1637Yes
115MSRB2MSRB219719-0.046-0.1560Yes
116POPDC3POPDC319791-0.047-0.1455Yes
117SLC16A7SLC16A719910-0.049-0.1366Yes
118ACYP2ACYP220030-0.050-0.1274Yes
119SERPINI1SERPINI120241-0.053-0.1215Yes
120ANKS1BANKS1B20262-0.054-0.1065Yes
121HPRT1HPRT120301-0.055-0.0922Yes
122CRYL1CRYL120724-0.064-0.0931Yes
123ZNF323ZNF32320788-0.066-0.0766Yes
124FEZF2FEZF221069-0.076-0.0675Yes
125SPASTSPAST21117-0.078-0.0468Yes
126MRPL49MRPL4921214-0.084-0.0265Yes
127SLC31A2SLC31A221529-0.1500.0031Yes
Table: GSEA details [plain text format]



Fig 2: VERHAAK_NEU_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_NEU_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_NEU_2010