Details for gene set VERHAAK_MES

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	VERHAAK_MES_2010
Enrichment Score (ES)	-0.41741687
Normalized Enrichment Score (NES)	-1.8966436
Nominal p-value	0.0
FDR q-value	0.0014184209
FWER p-Value	0.004

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLC16A3	SLC16A3	31	0.173	0.0196	No
2	ANXA2	ANXA2	41	0.164	0.0389	No
3	ANXA1	ANXA1	87	0.133	0.0530	No
4	TGFBI	TGFBI	137	0.111	0.0641	No
5	LAMB1	LAMB1	150	0.108	0.0765	No
6	CCDC109B	CCDC109B	170	0.105	0.0884	No
7	PYGL	PYGL	230	0.096	0.0972	No
8	ST14	ST14	402	0.082	0.0992	No
9	MRC2	MRC2	789	0.066	0.0892	No
10	SCPEP1	SCPEP1	820	0.065	0.0956	No
11	TGFBR2	TGFBR2	835	0.065	0.1028	No
12	ZNF217	ZNF217	879	0.063	0.1085	No
13	FCGR2B	FCGR2B	886	0.063	0.1159	No
14	EFEMP2	EFEMP2	1047	0.060	0.1156	No
15	SIGLEC9	SIGLEC9	1342	0.054	0.1083	No
16	COL5A1	COL5A1	1392	0.053	0.1124	No
17	RBMS1	RBMS1	1489	0.051	0.1142	No
18	THBD	THBD	1759	0.048	0.1073	No
19	WIPF1	WIPF1	1992	0.045	0.1019	No
20	CNN2	CNN2	2016	0.045	0.1062	No
21	SHC1	SHC1	2099	0.044	0.1077	No
22	CLEC2B	CLEC2B	2106	0.043	0.1126	No
23	SYPL1	SYPL1	2200	0.042	0.1134	No
24	LGALS3	LGALS3	2318	0.041	0.1129	No
25	LCP1	LCP1	2414	0.040	0.1133	No
26	CD2AP	CD2AP	2453	0.040	0.1163	No
27	TES	TES	2692	0.038	0.1098	No
28	FXYD5	FXYD5	3344	0.033	0.0833	No
29	TRADD	TRADD	3580	0.031	0.0760	No
30	FNDC3B	FNDC3B	3596	0.031	0.0791	No
31	FES	FES	3658	0.030	0.0799	No
32	TNFAIP8	TNFAIP8	4128	0.027	0.0613	No
33	HEXA	HEXA	4265	0.027	0.0582	No
34	FER1L3	FER1L3	4388	0.026	0.0556	No
35	ARHGAP29	ARHGAP29	4409	0.026	0.0578	No
36	PIGP	PIGP	4429	0.026	0.0600	No
37	ITGAM	ITGAM	4691	0.024	0.0507	No
38	IL15RA	IL15RA	4976	0.023	0.0402	No
39	LOX	LOX	5014	0.022	0.0412	No
40	MAN2B1	MAN2B1	5141	0.022	0.0379	No
41	TGOLN2	TGOLN2	5196	0.022	0.0380	No
42	SLC11A1	SLC11A1	5678	0.019	0.0178	No
43	ENG	ENG	5719	0.019	0.0182	No
44	RAB32	RAB32	5770	0.019	0.0182	No
45	MAN1A1	MAN1A1	6191	0.017	0.0006	No
46	NCF4	NCF4	6514	0.016	-0.0126	No
47	COL8A2	COL8A2	6523	0.015	-0.0111	No
48	NRP1	NRP1	6636	0.015	-0.0145	No
49	TEC	TEC	6651	0.015	-0.0134	No
50	LAIR1	LAIR1	7013	0.013	-0.0286	No
51	BDKRB2	BDKRB2	7039	0.013	-0.0282	No
52	HK3	HK3	7250	0.012	-0.0365	No
53	MAPK13	MAPK13	7296	0.012	-0.0371	No
54	PLS3	PLS3	7307	0.012	-0.0361	No
55	FLJ22662	FLJ22662	7392	0.012	-0.0386	No
56	CASP5	CASP5	7584	0.011	-0.0462	No
57	LY75	LY75	7705	0.011	-0.0505	No
58	BATF	BATF	7729	0.011	-0.0503	No
59	FOLR2	FOLR2	7819	0.010	-0.0532	No
60	IL1R1	IL1R1	7833	0.010	-0.0525	No
61	DOK3	DOK3	8275	0.009	-0.0721	No
62	AMPD3	AMPD3	8352	0.008	-0.0747	No
63	FCGR2A	FCGR2A	8432	0.008	-0.0774	No
64	TCIRG1	TCIRG1	8678	0.007	-0.0880	No
65	NOD2	NOD2	8780	0.007	-0.0919	No
66	PTPN22	PTPN22	9047	0.006	-0.1036	No
67	ECGF1	ECGF1	9283	0.005	-0.1140	No
68	ALOX5	ALOX5	9377	0.005	-0.1178	No
69	CDCP1	CDCP1	9398	0.005	-0.1182	No
70	RAC2	RAC2	9455	0.004	-0.1203	No
71	TLR2	TLR2	9697	0.003	-0.1311	No
72	PHF11	PHF11	9830	0.003	-0.1370	No
73	RHOG	RHOG	9834	0.003	-0.1368	No
74	ITGA4	ITGA4	9898	0.003	-0.1394	No
75	COL1A2	COL1A2	9939	0.003	-0.1409	No
76	TRIM38	TRIM38	10082	0.002	-0.1473	No
77	SFT2D2	SFT2D2	10153	0.002	-0.1504	No
78	TLR4	TLR4	10298	0.001	-0.1570	No
79	TNFRSF11A	TNFRSF11A	10308	0.001	-0.1572	No
80	PTPN6	PTPN6	10380	0.001	-0.1604	No
81	SLAMF8	SLAMF8	10547	0.000	-0.1682	No
82	CASP8	CASP8	10557	0.000	-0.1685	No
83	HFE	HFE	10660	0.000	-0.1733	No
84	ASL	ASL	10673	-0.000	-0.1739	No
85	GNA15	GNA15	10715	-0.000	-0.1758	No
86	THBS1	THBS1	10919	-0.001	-0.1852	No
87	PTPRC	PTPRC	10983	-0.001	-0.1880	No
88	ACPP	ACPP	10996	-0.001	-0.1884	No
89	DSC2	DSC2	11016	-0.001	-0.1892	No
90	RABGAP1L	RABGAP1L	11078	-0.001	-0.1918	No
91	ADAM12	ADAM12	11250	-0.002	-0.1996	No
92	GRN	GRN	11270	-0.002	-0.2002	No
93	MYO1F	MYO1F	11289	-0.002	-0.2008	No
94	KYNU	KYNU	11298	-0.002	-0.2009	No
95	MSR1	MSR1	11351	-0.002	-0.2030	No
96	TNFRSF1A	TNFRSF1A	11380	-0.003	-0.2040	No
97	PSCDBP	PSCDBP	11717	-0.004	-0.2193	No
98	LRRFIP1	LRRFIP1	12234	-0.005	-0.2428	No
99	S100A13	S100A13	12345	-0.006	-0.2472	No
100	LGALS1	LGALS1	12490	-0.006	-0.2532	No
101	GCNT1	GCNT1	12523	-0.007	-0.2539	No
102	LILRB2	LILRB2	12596	-0.007	-0.2564	No
103	RAB27A	RAB27A	12626	-0.007	-0.2569	No
104	WWTR1	WWTR1	12641	-0.007	-0.2568	No
105	C5AR1	C5AR1	12879	-0.008	-0.2669	No
106	SERPINA1	SERPINA1	12892	-0.008	-0.2665	No
107	GLT25D1	GLT25D1	12962	-0.008	-0.2688	No
108	DSE	DSE	13335	-0.009	-0.2850	No
109	SQRDL	SQRDL	13592	-0.010	-0.2957	No
110	STXBP2	STXBP2	13597	-0.010	-0.2946	No
111	LILRB3	LILRB3	13888	-0.012	-0.3068	No
112	RELB	RELB	14022	-0.012	-0.3116	No
113	NPC2	NPC2	14183	-0.013	-0.3175	No
114	ITGB2	ITGB2	14233	-0.013	-0.3182	No
115	NCF2	NCF2	14311	-0.013	-0.3202	No
116	SAT1	SAT1	14351	-0.013	-0.3204	No
117	RAB11FIP1	RAB11FIP1	14584	-0.014	-0.3295	No
118	ANXA4	ANXA4	14597	-0.014	-0.3284	No
119	BNC2	BNC2	14603	-0.014	-0.3269	No
120	PGCP	PGCP	14738	-0.015	-0.3313	No
121	SIGLEC7	SIGLEC7	14855	-0.015	-0.3349	No
122	COL1A1	COL1A1	14878	-0.016	-0.3340	No
123	VDR	VDR	15499	-0.018	-0.3608	No
124	RUNX2	RUNX2	15638	-0.019	-0.3650	No
125	PTGER4	PTGER4	15657	-0.019	-0.3636	No
126	IL4R	IL4R	15794	-0.020	-0.3676	No
127	YAP1	YAP1	15834	-0.020	-0.3670	No
128	MYH9	MYH9	15863	-0.020	-0.3659	No
129	FHL2	FHL2	15905	-0.020	-0.3654	No
130	PDPN	PDPN	16322	-0.022	-0.3822	No
131	CSTA	CSTA	16659	-0.024	-0.3950	No
132	SRPX2	SRPX2	16721	-0.024	-0.3950	No
133	STAB1	STAB1	16747	-0.024	-0.3933	No
134	FMNL1	FMNL1	16757	-0.024	-0.3908	No
135	SWAP70	SWAP70	16826	-0.024	-0.3910	No
136	MS4A4A	MS4A4A	16861	-0.025	-0.3896	No
137	MFSD1	MFSD1	16982	-0.025	-0.3922	No
138	FHOD1	FHOD1	17016	-0.025	-0.3907	No
139	CASP4	CASP4	17111	-0.026	-0.3919	No
140	LCP2	LCP2	17322	-0.027	-0.3985	No
141	CTSZ	CTSZ	17374	-0.027	-0.3976	No
142	STAT6	STAT6	17480	-0.028	-0.3991	No
143	CD4	CD4	17521	-0.028	-0.3976	No
144	MAFB	MAFB	17593	-0.029	-0.3974	No
145	MGAT1	MGAT1	17652	-0.029	-0.3966	No
146	CASP1	CASP1	17665	-0.029	-0.3937	No
147	SYNGR2	SYNGR2	17709	-0.029	-0.3922	No
148	HEXB	HEXB	17761	-0.029	-0.3910	No
149	DAB2	DAB2	18163	-0.032	-0.4059	No
150	TRPM2	TRPM2	18171	-0.032	-0.4023	No
151	MVP	MVP	18318	-0.033	-0.4051	No
152	CTSB	CTSB	18445	-0.034	-0.4069	No
153	C1orf38	C1orf38	18543	-0.035	-0.4072	No
154	POLD4	POLD4	18762	-0.037	-0.4130	Yes
155	SP100	SP100	18830	-0.037	-0.4116	Yes
156	UAP1	UAP1	18886	-0.038	-0.4096	Yes
157	ARSJ	ARSJ	18970	-0.038	-0.4089	Yes
158	PSCD4	PSCD4	19101	-0.040	-0.4102	Yes
159	TMBIM1	TMBIM1	19162	-0.040	-0.4081	Yes
160	PLK3	PLK3	19168	-0.040	-0.4034	Yes
161	C1orf54	C1orf54	19444	-0.043	-0.4111	Yes
162	P4HA2	P4HA2	19472	-0.043	-0.4071	Yes
163	SEC24D	SEC24D	19494	-0.043	-0.4029	Yes
164	CAST	CAST	19519	-0.044	-0.3987	Yes
165	PLAUR	PLAUR	19606	-0.045	-0.3973	Yes
166	SLC10A3	SLC10A3	19691	-0.046	-0.3957	Yes
167	LHFPL2	LHFPL2	19740	-0.046	-0.3923	Yes
168	CD14	CD14	19758	-0.047	-0.3875	Yes
169	UCP2	UCP2	19769	-0.047	-0.3823	Yes
170	EMP3	EMP3	19792	-0.047	-0.3776	Yes
171	ELF4	ELF4	19885	-0.048	-0.3761	Yes
172	CTSC	CTSC	19916	-0.049	-0.3716	Yes
173	AIM1	AIM1	20012	-0.050	-0.3700	Yes
174	ITGA5	ITGA5	20099	-0.051	-0.3678	Yes
175	PTRF	PTRF	20222	-0.053	-0.3670	Yes
176	CLIC1	CLIC1	20260	-0.054	-0.3622	Yes
177	TRIM22	TRIM22	20318	-0.055	-0.3583	Yes
178	CCR5	CCR5	20451	-0.057	-0.3575	Yes
179	CYBRD1	CYBRD1	20489	-0.058	-0.3522	Yes
180	LAPTM5	LAPTM5	20687	-0.063	-0.3538	Yes
181	RRAS	RRAS	20702	-0.064	-0.3468	Yes
182	RBKS	RBKS	20720	-0.064	-0.3398	Yes
183	FLJ20273	FLJ20273	20768	-0.065	-0.3341	Yes
184	ACSL1	ACSL1	20777	-0.065	-0.3266	Yes
185	S100A4	S100A4	20836	-0.067	-0.3211	Yes
186	EHD2	EHD2	20980	-0.072	-0.3191	Yes
187	IGFBP6	IGFBP6	21022	-0.074	-0.3121	Yes
188	TIMP1	TIMP1	21029	-0.074	-0.3034	Yes
189	S100A11	S100A11	21047	-0.075	-0.2952	Yes
190	COPZ2	COPZ2	21048	-0.075	-0.2861	Yes
191	ICAM3	ICAM3	21100	-0.077	-0.2792	Yes
192	LTBP1	LTBP1	21123	-0.078	-0.2708	Yes
193	IQGAP1	IQGAP1	21134	-0.079	-0.2617	Yes
194	ARPC1B	ARPC1B	21177	-0.082	-0.2537	Yes
195	ALDH3B1	ALDH3B1	21240	-0.086	-0.2462	Yes
196	LTBP2	LTBP2	21266	-0.088	-0.2367	Yes
197	IFI30	IFI30	21281	-0.089	-0.2266	Yes
198	CEBPB	CEBPB	21289	-0.090	-0.2161	Yes
199	FURIN	FURIN	21311	-0.092	-0.2060	Yes
200	SH2B3	SH2B3	21319	-0.093	-0.1951	Yes
201	PROCR	PROCR	21321	-0.093	-0.1838	Yes
202	BLVRB	BLVRB	21350	-0.098	-0.1733	Yes
203	MGST2	MGST2	21358	-0.098	-0.1617	Yes
204	MAN2A1	MAN2A1	21374	-0.101	-0.1502	Yes
205	DCBLD2	DCBLD2	21387	-0.103	-0.1384	Yes
206	LY96	LY96	21395	-0.104	-0.1261	Yes
207	VAMP5	VAMP5	21463	-0.116	-0.1152	Yes
208	TNFAIP3	TNFAIP3	21499	-0.132	-0.1009	Yes
209	PLAU	PLAU	21507	-0.141	-0.0842	Yes
210	CLCF1	CLCF1	21517	-0.146	-0.0670	Yes
211	SERPINE1	SERPINE1	21554	-0.173	-0.0477	Yes
212	CHI3L1	CHI3L1	21572	-0.194	-0.0250	Yes
213	TNFRSF1B	TNFRSF1B	21580	-0.215	0.0007	Yes