DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetVERHAAK_CL_2010
Enrichment Score (ES)0.28641808
Normalized Enrichment Score (NES)1.2468582
Nominal p-value0.06451613
FDR q-value0.13352494
FWER p-Value0.783
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_CL_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1TBX2TBX22140.0980.0100Yes
2LHFPLHFP2430.0950.0279Yes
3WSCD1WSCD12540.0930.0464Yes
4IRS2IRS23020.0900.0626Yes
5CDK6CDK64130.0820.0741Yes
6FZD3FZD34250.0810.0901Yes
7ZNF211ZNF2116580.0710.0936Yes
8PRPF31PRPF316590.0710.1080Yes
9PTPN14PTPN147180.0690.1193Yes
10LFNGLFNG7590.0670.1311Yes
11NDPNDP8290.0650.1411Yes
12BTBD2BTBD28680.0640.1523Yes
13FZD7FZD78720.0640.1651Yes
14ITGB8ITGB89080.0630.1762Yes
15ANXA5ANXA59930.0610.1846Yes
16GPR56GPR5610190.0600.1957Yes
17SMOSMO10350.0600.2071Yes
18NR2E1NR2E110680.0590.2177Yes
19RBM42RBM4211400.0580.2262Yes
20RGS6RGS616610.0490.2119Yes
21ZNF671ZNF67116730.0490.2213Yes
22SIPA1L1SIPA1L117680.0470.2265Yes
23DMWDDMWD18630.0460.2315Yes
24KEAP1KEAP118670.0460.2408Yes
25HSPBP1HSPBP118850.0460.2494Yes
26QTRT1QTRT118930.0460.2584Yes
27ZFHX4ZFHX419420.0450.2654Yes
28DAG1DAG121590.0430.2640Yes
29KIAA0355KIAA035521800.0430.2717Yes
30GLI2GLI222520.0420.2769Yes
31SOX9SOX923230.0410.2819Yes
32ZNF304ZNF30424990.0390.2818Yes
33TMEM161ATMEM161A26940.0380.2804Yes
34VPS16VPS1631800.0340.2647Yes
35VAV3VAV332180.0340.2698Yes
36PEPDPEPD32730.0330.2740Yes
37SNTA1SNTA134560.0320.2719Yes
38EGFREGFR35170.0310.2755Yes
39CDH2CDH235360.0310.2810Yes
40PMP22PMP2236400.0310.2824Yes
41ACSL3ACSL337180.0300.2850Yes
42RFXANKRFXANK38780.0290.2834Yes
43CDH4CDH439390.0290.2864Yes
44CD3EAPCD3EAP43850.0260.2709No
45FGFR3FGFR345010.0250.2707No
46SLC4A4SLC4A445380.0250.2741No
47POMT2POMT245730.0250.2776No
48GJA1GJA146000.0250.2814No
49LAMB2LAMB249600.0230.2693No
50ZNF45ZNF4549740.0230.2732No
51ZNF235ZNF23549920.0230.2770No
52TGIF2TGIF251570.0220.2738No
53PTPRAPTPRA52690.0210.2729No
54KLHDC8AKLHDC8A54970.0200.2664No
55RFX2RFX256470.0190.2634No
56ZNF134ZNF13457420.0190.2628No
57B3GALT1B3GALT165490.0150.2284No
58MEOX2MEOX268350.0140.2179No
59LMO2LMO271820.0130.2044No
60CC2D1ACC2D1A72130.0130.2055No
61GSTK1GSTK172720.0120.2054No
62SLC6A11SLC6A1173460.0120.2044No
63CREB5CREB573630.0120.2061No
64TEAD3TEAD375360.0110.2004No
65DLC1DLC181590.0090.1732No
66TRIB2TRIB286470.0070.1520No
67RBCK1RBCK188280.0070.1449No
68DOCK6DOCK688950.0060.1431No
69PDGFAPDGFA90460.0060.1373No
70SCAMP4SCAMP493450.0050.1244No
71ILKILK93850.0050.1235No
72MLC1MLC194690.0040.1205No
73GRIK1GRIK195860.0040.1158No
74TMED1TMED197530.0030.1087No
75PLA2G5PLA2G598250.0030.1060No
76SARS2SARS298280.0030.1065No
77DENND2ADENND2A98910.0030.1041No
78RGS12RGS1298960.0030.1045No
79ELOVL2ELOVL2104750.0010.0777No
80NPEPL1NPEPL111036-0.0010.0518No
81MAB21L1MAB21L111085-0.0010.0499No
82ERCC2ERCC211147-0.0020.0474No
83EYA2EYA211213-0.0020.0447No
84ZNF20ZNF2011223-0.0020.0447No
85AKT2AKT211421-0.0030.0360No
86LRP10LRP1011474-0.0030.0342No
87C19orf22C19orf2211484-0.0030.0344No
88ACSBG1ACSBG112021-0.0050.0103No
89GLG1GLG112198-0.0050.0032No
90MYO5CMYO5C12276-0.0060.0007No
91TRIP6TRIP612336-0.006-0.0008No
92GNASGNAS12432-0.006-0.0040No
93LRRC16LRRC1612465-0.006-0.0042No
94ARNTLARNTL12633-0.007-0.0106No
95NR2F6NR2F612640-0.007-0.0095No
96CDH6CDH612859-0.008-0.0181No
97SHOX2SHOX212923-0.008-0.0194No
98SOCS2SOCS212965-0.008-0.0196No
99CD97CD9712979-0.008-0.0186No
100CENTD1CENTD113241-0.009-0.0289No
101JAG1JAG113262-0.009-0.0280No
102CD151CD15113304-0.009-0.0280No
103FBXO17FBXO1713319-0.009-0.0267No
104IRF3IRF313414-0.010-0.0291No
105ABCD2ABCD213424-0.010-0.0275No
106ZNF8ZNF814099-0.012-0.0564No
107SLC2A10SLC2A1014204-0.013-0.0587No
108TGFB3TGFB314231-0.013-0.0573No
109APBA3APBA314234-0.013-0.0547No
110PIPOXPIPOX14260-0.013-0.0532No
111MEGF8MEGF814380-0.014-0.0560No
112JUNDJUND14460-0.014-0.0569No
113ZNF419ZNF41914479-0.014-0.0549No
114LRP5LRP514516-0.014-0.0537No
115KLHL25KLHL2514523-0.014-0.0512No
116TMEM147TMEM14714641-0.015-0.0537No
117MEIS1MEIS114829-0.015-0.0593No
118ZNF227ZNF22715043-0.016-0.0659No
119ZNF606ZNF60615137-0.017-0.0669No
120PCSK5PCSK515516-0.018-0.0808No
121NESNES15616-0.019-0.0816No
122GRIK5GRIK515628-0.019-0.0783No
123MGC2752MGC275215906-0.020-0.0872No
124EXTL3EXTL316028-0.021-0.0886No
125MCCMCC16327-0.022-0.0981No
126NPAS3NPAS316347-0.022-0.0945No
127ITGA7ITGA716442-0.022-0.0943No
128SPRY2SPRY216493-0.023-0.0920No
129TLE2TLE216986-0.025-0.1098No
130GALNT4GALNT416989-0.025-0.1048No
131HS3ST3B1HS3ST3B117068-0.026-0.1032No
132SLC6A9SLC6A917309-0.027-0.1090No
133RASGRP1RASGRP117827-0.030-0.1270No
134POFUT1POFUT118272-0.033-0.1410No
135ZNF264ZNF26418741-0.036-0.1555No
136EPHB4EPHB418748-0.036-0.1484No
137SSH3SSH318771-0.037-0.1419No
138ADAM19ADAM1918801-0.037-0.1358No
139SEMA6DSEMA6D18870-0.038-0.1313No
140ZNF446ZNF44619404-0.042-0.1476No
141CALM1CALM119460-0.043-0.1414No
142SEMA6ASEMA6A19784-0.047-0.1469No
143BLMBLM20072-0.051-0.1500No
144LRFN3LRFN320177-0.052-0.1442No
145CLIP2CLIP220211-0.053-0.1350No
146OSBPL3OSBPL320251-0.054-0.1259No
147GAS1GAS120486-0.058-0.1250No
148PRKD2PRKD220637-0.062-0.1195No
149M6PRBP1M6PRBP120748-0.065-0.1115No
150SLC12A4SLC12A420790-0.066-0.1000No
151GNG7GNG720829-0.067-0.0881No
152RIN1RIN120944-0.071-0.0790No
153HMG20BHMG20B21026-0.074-0.0678No
154KLHL4KLHL421129-0.079-0.0566No
155CAMK2BCAMK2B21401-0.105-0.0480No
156NOS2ANOS2A21431-0.108-0.0273No
157KCNF1KCNF121551-0.1720.0021No
Table: GSEA details [plain text format]



Fig 2: VERHAAK_CL_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_CL_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_CL_2010