DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetVDR_REGULON
Enrichment Score (ES)-0.298967
Normalized Enrichment Score (NES)-1.2960764
Nominal p-value0.044487428
FDR q-value0.08163539
FWER p-Value0.673
Table: GSEA Results Summary



Fig 1: Enrichment plot: VDR_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PTPRDPTPRD90.2410.0552No
2HMBOX1HMBOX12470.0940.0660No
3MPZMPZ7070.0690.0606No
4ABATABAT8060.0660.0711No
5ALDH3A1ALDH3A19040.0630.0811No
6TCF12TCF1211950.0570.0806No
7PVRPVR13930.0530.0836No
8TRIM24TRIM2416260.0490.0843No
9HLA-DQB1HLA-DQB117490.0480.0896No
10GPRC5AGPRC5A20520.0440.0857No
11TBX3TBX323010.0410.0837No
12MID2MID223080.0410.0929No
13FLI1FLI125180.0390.0922No
14IPPKIPPK25750.0390.0985No
15ABL2ABL227050.0380.1012No
16ICOSLGICOSLG29850.0350.0964No
17JUPJUP33500.0330.0870No
18TUBB2ATUBB2A34280.0320.0908No
19PTPRUPTPRU35700.0310.0914No
20STEAP3STEAP337940.0290.0878No
21RAD50RAD5039420.0280.0875No
22ADRB2ADRB242720.0270.0783No
23KRT7KRT744910.0250.0740No
24LRRC8ELRRC8E44960.0250.0797No
25STEAP1STEAP147670.0240.0725No
26IL15RAIL15RA49760.0230.0681No
27ASPHASPH52150.0210.0619No
28ZFRZFR52720.0210.0642No
29PNMA2PNMA255580.0200.0555No
30SOX11SOX1157680.0190.0501No
31ITPR3ITPR358080.0190.0526No
32GALNT6GALNT658290.0190.0559No
33S100A8S100A860030.0180.0520No
34C9orf3C9orf360080.0180.0559No
35CHD7CHD760150.0180.0597No
36FAM114A1FAM114A160370.0180.0627No
37MARK1MARK160780.0170.0649No
38SRGNSRGN62010.0170.0631No
39AKR1C1AKR1C165480.0150.0505No
40TNFSF9TNFSF967920.0140.0425No
41LLGL2LLGL268680.0140.0422No
42APOL1APOL169270.0140.0427No
43NAV3NAV370540.0130.0399No
44CDC42EP1CDC42EP173760.0120.0277No
45BCL2A1BCL2A174410.0120.0274No
46PHLPP1PHLPP175980.0110.0227No
47ME1ME176590.0110.0224No
48TGM2TGM277520.0110.0206No
49C16orf71C16orf7178160.0100.0201No
50IL1R1IL1R178330.0100.0217No
51IL15IL1580400.0090.0143No
52CHST15CHST1582430.0090.0069No
53TRAF3IP1TRAF3IP183940.0080.0018No
54LAMC2LAMC284180.0080.0025No
55TCIRG1TCIRG186780.007-0.0079No
56ABLIM3ABLIM386940.007-0.0069No
57PI15PI1588690.006-0.0136No
58S100A2S100A290270.006-0.0196No
59TNNC2TNNC292350.005-0.0280No
60ACSL5ACSL592570.005-0.0278No
61CDCP1CDCP193980.005-0.0333No
62TNNT1TNNT195660.004-0.0402No
63SP140LSP140L96200.004-0.0418No
64IL24IL2498220.003-0.0506No
65HPCAL1HPCAL1100030.002-0.0584No
66TRIM38TRIM38100820.002-0.0616No
67CBR1CBR1100850.002-0.0612No
68MCOLN3MCOLN3103640.001-0.0739No
69SPAG1SPAG1104120.001-0.0759No
70DCAF7DCAF7104500.001-0.0775No
71CDS1CDS1105850.000-0.0836No
72LAMB3LAMB3106020.000-0.0843No
73AOX1AOX110665-0.000-0.0872No
74G0S2G0S211140-0.002-0.1089No
75HTR7HTR711232-0.002-0.1127No
76KYNUKYNU11298-0.002-0.1153No
77MAGEB2MAGEB211801-0.004-0.1377No
78GMDSGMDS11876-0.004-0.1402No
79HMGA1HMGA111895-0.004-0.1401No
80PHF7PHF712048-0.005-0.1461No
81TMEM40TMEM4012102-0.005-0.1474No
82AGPAT2AGPAT212113-0.005-0.1467No
83PIK3CDPIK3CD12129-0.005-0.1462No
84C1orf61C1orf6112173-0.005-0.1470No
85TNFAIP2TNFAIP212244-0.006-0.1490No
86CXCL3CXCL312327-0.006-0.1514No
87PLEK2PLEK212406-0.006-0.1537No
88GCNT1GCNT112523-0.007-0.1576No
89RAB27ARAB27A12626-0.007-0.1607No
90EVI2AEVI2A12796-0.007-0.1669No
91GPR39GPR3912880-0.008-0.1690No
92SERPINA1SERPINA112892-0.008-0.1677No
93DOCK2DOCK213017-0.008-0.1715No
94ABCA7ABCA713097-0.009-0.1732No
95BANK1BANK113225-0.009-0.1770No
96DENND3DENND313479-0.010-0.1865No
97PKP3PKP313678-0.011-0.1933No
98COL17A1COL17A113955-0.012-0.2034No
99STARD5STARD514125-0.013-0.2084No
100MMEMME14310-0.013-0.2139No
101SPINT1SPINT114601-0.014-0.2241No
102CD55CD5515072-0.016-0.2423No
103SPAG4SPAG415315-0.017-0.2495No
104ID4ID415399-0.018-0.2493No
105SERPINB7SERPINB715479-0.018-0.2488No
106CCND3CCND315504-0.018-0.2458No
107TRAPPC10TRAPPC1016153-0.021-0.2711No
108SALL2SALL216354-0.022-0.2753No
109UBE2ZUBE2Z16451-0.023-0.2746No
110FMNL1FMNL116757-0.024-0.2833No
111YWHAEYWHAE17050-0.026-0.2910No
112PDCD1LG2PDCD1LG217082-0.026-0.2865No
113CASP4CASP417111-0.026-0.2818No
114STAT6STAT617480-0.028-0.2925Yes
115MSX2MSX217495-0.028-0.2867Yes
116SVILSVIL17535-0.028-0.2820Yes
117EXPH5EXPH517572-0.028-0.2771Yes
118IL2RBIL2RB17658-0.029-0.2744Yes
119SYNGR2SYNGR217709-0.029-0.2700Yes
120NCANNCAN17822-0.030-0.2683Yes
121RIPK4RIPK417844-0.030-0.2624Yes
122TFAP2CTFAP2C17889-0.030-0.2574Yes
123PRKCDPRKCD18125-0.032-0.2611Yes
124SELPLGSELPLG18133-0.032-0.2540Yes
125MAP3K1MAP3K118630-0.035-0.2690Yes
126MYO1DMYO1D18698-0.036-0.2638Yes
127PRICKLE3PRICKLE318763-0.037-0.2583Yes
128SDC1SDC118831-0.037-0.2528Yes
129ADARB1ADARB118888-0.038-0.2468Yes
130TNFRSF10DTNFRSF10D18900-0.038-0.2385Yes
131DNASE1L1DNASE1L118949-0.038-0.2319Yes
132LTBRLTBR18956-0.038-0.2234Yes
133ENOX2ENOX219508-0.044-0.2390Yes
134SLC10A3SLC10A319691-0.046-0.2369Yes
135JPH2JPH219706-0.046-0.2270Yes
136PLEKHO1PLEKHO119793-0.047-0.2201Yes
137TRAF1TRAF119832-0.048-0.2109Yes
138C3C320052-0.051-0.2094Yes
139CXCL1CXCL120079-0.051-0.1988Yes
140VNN1VNN120294-0.054-0.1962Yes
141SMARCD2SMARCD220295-0.054-0.1836Yes
142PTPRHPTPRH20410-0.056-0.1759Yes
143STX11STX1120425-0.057-0.1634Yes
144IQSEC2IQSEC220471-0.058-0.1522Yes
145NFKBIENFKBIE20540-0.059-0.1418Yes
146SLC9A7SLC9A720719-0.064-0.1353Yes
147SH3TC1SH3TC120896-0.069-0.1275Yes
148IGFBP6IGFBP621022-0.074-0.1163Yes
149CPPED1CPPED121119-0.078-0.1028Yes
150CYB5R2CYB5R221152-0.080-0.0858Yes
151PLP2PLP221203-0.083-0.0688Yes
152LTBP2LTBP221266-0.088-0.0514Yes
153TPMTTPMT21478-0.121-0.0332Yes
154FOSL1FOSL121546-0.1670.0023Yes
Table: GSEA details [plain text format]



Fig 2: VDR_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VDR_REGULON: Random ES distribution   
Gene set null distribution of ES for VDR_REGULON