Details for gene set SP100

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	SP100_REGULON
Enrichment Score (ES)	-0.39346373
Normalized Enrichment Score (NES)	-1.692748
Nominal p-value	0.0
FDR q-value	0.0040680408
FWER p-Value	0.028

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1R	C1R	108	0.120	0.0214	No
2	MTSS1	MTSS1	362	0.085	0.0283	No
3	SDF4	SDF4	616	0.072	0.0323	No
4	HCFC2	HCFC2	763	0.067	0.0403	No
5	E2F5	E2F5	815	0.065	0.0523	No
6	SCPEP1	SCPEP1	820	0.065	0.0664	No
7	IFI16	IFI16	831	0.065	0.0801	No
8	RAB11FIP5	RAB11FIP5	875	0.064	0.0921	No
9	NUDT11	NUDT11	1306	0.054	0.0840	No
10	NMI	NMI	1355	0.053	0.0935	No
11	SP110	SP110	1523	0.051	0.0969	No
12	RETSAT	RETSAT	1685	0.049	0.1000	No
13	OSTF1	OSTF1	1920	0.046	0.0992	No
14	SHC1	SHC1	2099	0.044	0.1004	No
15	CLEC2B	CLEC2B	2106	0.043	0.1097	No
16	TRIM5	TRIM5	2928	0.036	0.0793	No
17	TRADD	TRADD	3580	0.031	0.0558	No
18	CBX5	CBX5	3641	0.031	0.0597	No
19	C1QTNF1	C1QTNF1	3773	0.030	0.0601	No
20	KBTBD11	KBTBD11	3871	0.029	0.0620	No
21	LPAR1	LPAR1	3933	0.029	0.0654	No
22	DDX58	DDX58	3946	0.028	0.0711	No
23	NLRP1	NLRP1	4727	0.024	0.0400	No
24	B2M	B2M	5076	0.022	0.0286	No
25	ELK3	ELK3	5298	0.021	0.0229	No
26	MGLL	MGLL	5571	0.020	0.0146	No
27	SOX11	SOX11	5768	0.019	0.0096	No
28	CHD7	CHD7	6015	0.018	0.0020	No
29	SEPHS1	SEPHS1	6256	0.017	-0.0055	No
30	GBP1	GBP1	6648	0.015	-0.0205	No
31	SMAGP	SMAGP	6881	0.014	-0.0282	No
32	APOL1	APOL1	6927	0.014	-0.0273	No
33	RNASEL	RNASEL	6951	0.014	-0.0254	No
34	LNPEP	LNPEP	7078	0.013	-0.0284	No
35	YPEL1	YPEL1	7294	0.012	-0.0357	No
36	TRIM21	TRIM21	7539	0.011	-0.0446	No
37	HLA-B	HLA-B	7810	0.010	-0.0548	No
38	HLA-F	HLA-F	8223	0.009	-0.0721	No
39	OAS2	OAS2	8425	0.008	-0.0797	No
40	TCIRG1	TCIRG1	8678	0.007	-0.0899	No
41	DENND4A	DENND4A	8742	0.007	-0.0913	No
42	MDFIC	MDFIC	8822	0.007	-0.0936	No
43	HERC6	HERC6	8899	0.006	-0.0957	No
44	BTN3A3	BTN3A3	9289	0.005	-0.1127	No
45	CUEDC2	CUEDC2	9311	0.005	-0.1127	No
46	DDX60	DDX60	9347	0.005	-0.1132	No
47	ERAP1	ERAP1	9374	0.005	-0.1134	No
48	SP140L	SP140L	9620	0.004	-0.1240	No
49	PHF11	PHF11	9830	0.003	-0.1331	No
50	SLFN12	SLFN12	9836	0.003	-0.1328	No
51	TRIM38	TRIM38	10082	0.002	-0.1437	No
52	NPTN	NPTN	10169	0.002	-0.1473	No
53	PSMB9	PSMB9	10207	0.002	-0.1487	No
54	TMEM140	TMEM140	10443	0.001	-0.1595	No
55	CASP8	CASP8	10557	0.000	-0.1647	No
56	PML	PML	10625	0.000	-0.1678	No
57	HFE	HFE	10660	0.000	-0.1693	No
58	HLA-E	HLA-E	11037	-0.001	-0.1866	No
59	LRP10	LRP10	11474	-0.003	-0.2063	No
60	TAPBPL	TAPBPL	11983	-0.005	-0.2289	No
61	XAF1	XAF1	12073	-0.005	-0.2320	No
62	CAMKV	CAMKV	12586	-0.007	-0.2544	No
63	RAB27A	RAB27A	12626	-0.007	-0.2547	No
64	GNS	GNS	12627	-0.007	-0.2532	No
65	ITGBL1	ITGBL1	12642	-0.007	-0.2523	No
66	DDO	DDO	12952	-0.008	-0.2649	No
67	APOL3	APOL3	13025	-0.008	-0.2665	No
68	HLA-C	HLA-C	13036	-0.008	-0.2651	No
69	ASB13	ASB13	13194	-0.009	-0.2704	No
70	ERAP2	ERAP2	13347	-0.010	-0.2754	No
71	APOM	APOM	14093	-0.012	-0.3074	No
72	ANXA4	ANXA4	14597	-0.014	-0.3277	No
73	BIN1	BIN1	14717	-0.015	-0.3299	No
74	INTS9	INTS9	15069	-0.016	-0.3427	No
75	IRF2	IRF2	15223	-0.017	-0.3461	No
76	C19orf66	C19orf66	15338	-0.017	-0.3476	No
77	TLR3	TLR3	15426	-0.018	-0.3477	No
78	RUNX2	RUNX2	15638	-0.019	-0.3534	No
79	UTRN	UTRN	15859	-0.020	-0.3593	No
80	HERC5	HERC5	16012	-0.021	-0.3619	No
81	RALB	RALB	16034	-0.021	-0.3583	No
82	APOBEC3G	APOBEC3G	16135	-0.021	-0.3584	No
83	PPIC	PPIC	16165	-0.021	-0.3551	No
84	SALL2	SALL2	16354	-0.022	-0.3590	No
85	IFIT3	IFIT3	16496	-0.023	-0.3606	No
86	CYLD	CYLD	16905	-0.025	-0.3741	No
87	MFSD1	MFSD1	16982	-0.025	-0.3721	No
88	CASP4	CASP4	17111	-0.026	-0.3724	No
89	ICAM1	ICAM1	17117	-0.026	-0.3669	No
90	TAPBP	TAPBP	17481	-0.028	-0.3777	No
91	RTP4	RTP4	17640	-0.029	-0.3788	No
92	CASP1	CASP1	17665	-0.029	-0.3735	No
93	TPBG	TPBG	17767	-0.029	-0.3718	No
94	TAP1	TAP1	18234	-0.033	-0.3863	Yes
95	LRBA	LRBA	18305	-0.033	-0.3823	Yes
96	MVP	MVP	18318	-0.033	-0.3757	Yes
97	ALAD	ALAD	18331	-0.033	-0.3689	Yes
98	MX1	MX1	18439	-0.034	-0.3665	Yes
99	BST2	BST2	18775	-0.037	-0.3740	Yes
100	BACH2	BACH2	18961	-0.038	-0.3742	Yes
101	GATA6	GATA6	18967	-0.038	-0.3660	Yes
102	IFI35	IFI35	19250	-0.041	-0.3701	Yes
103	VRK1	VRK1	19288	-0.041	-0.3628	Yes
104	MR1	MR1	19310	-0.042	-0.3546	Yes
105	GSDMD	GSDMD	19363	-0.042	-0.3478	Yes
106	FLT3LG	FLT3LG	19490	-0.043	-0.3442	Yes
107	C1RL	C1RL	19665	-0.046	-0.3423	Yes
108	PARP12	PARP12	19840	-0.048	-0.3399	Yes
109	AMIGO2	AMIGO2	20174	-0.052	-0.3439	Yes
110	OSBPL3	OSBPL3	20251	-0.054	-0.3357	Yes
111	TBC1D8	TBC1D8	20453	-0.057	-0.3325	Yes
112	PARP3	PARP3	20533	-0.059	-0.3233	Yes
113	FAS	FAS	20765	-0.065	-0.3197	Yes
114	DHX58	DHX58	20776	-0.065	-0.3058	Yes
115	SAMD9	SAMD9	20789	-0.066	-0.2918	Yes
116	MMP14	MMP14	20926	-0.070	-0.2828	Yes
117	STAT1	STAT1	21042	-0.074	-0.2718	Yes
118	S100A11	S100A11	21047	-0.075	-0.2556	Yes
119	ARPC1B	ARPC1B	21177	-0.082	-0.2436	Yes
120	PLP2	PLP2	21203	-0.083	-0.2265	Yes
121	SECTM1	SECTM1	21221	-0.085	-0.2086	Yes
122	PSMB8	PSMB8	21234	-0.086	-0.1903	Yes
123	MICAL2	MICAL2	21308	-0.091	-0.1736	Yes
124	PROCR	PROCR	21321	-0.093	-0.1536	Yes
125	BLVRB	BLVRB	21350	-0.098	-0.1335	Yes
126	WIPI1	WIPI1	21433	-0.109	-0.1134	Yes
127	IRF1	IRF1	21459	-0.115	-0.0894	Yes
128	TNFRSF14	TNFRSF14	21471	-0.118	-0.0640	Yes
129	ITGB5	ITGB5	21506	-0.140	-0.0348	Yes
130	SLC16A6	SLC16A6	21559	-0.177	0.0017	Yes