Details for gene set SCHMITT_TNF

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	SCHMITT_TNF_2020
Enrichment Score (ES)	-0.3609119
Normalized Enrichment Score (NES)	-1.711786
Nominal p-value	0.0
FDR q-value	0.0039041655
FWER p-Value	0.022

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SPARCL1	SPARCL1	0	0.477	0.0365	No
2	SLC16A3	SLC16A3	31	0.173	0.0484	No
3	A2M	A2M	36	0.168	0.0610	No
4	IL1RAP	IL1RAP	42	0.163	0.0733	No
5	ANXA1	ANXA1	87	0.133	0.0814	No
6	ARRDC4	ARRDC4	232	0.096	0.0819	No
7	FZD5	FZD5	235	0.096	0.0892	No
8	MATN2	MATN2	265	0.093	0.0949	No
9	CD44	CD44	281	0.092	0.1012	No
10	ATCAY	ATCAY	286	0.092	0.1080	No
11	KLHL5	KLHL5	321	0.089	0.1132	No
12	PRKAR1B	PRKAR1B	387	0.083	0.1165	No
13	INSR	INSR	396	0.083	0.1224	No
14	NAMPT	NAMPT	433	0.081	0.1269	No
15	KLF5	KLF5	486	0.078	0.1305	No
16	PXDN	PXDN	490	0.078	0.1363	No
17	STAT3	STAT3	496	0.078	0.1421	No
18	SOCS3	SOCS3	538	0.076	0.1460	No
19	SLC16A9	SLC16A9	701	0.069	0.1437	No
20	TNFRSF9	TNFRSF9	706	0.069	0.1488	No
21	MPZ	MPZ	707	0.069	0.1540	No
22	F3	F3	837	0.065	0.1529	No
23	CSRP2	CSRP2	861	0.064	0.1568	No
24	CDKAL1	CDKAL1	930	0.062	0.1583	No
25	C4A	C4A	968	0.061	0.1613	No
26	SLC2A3	SLC2A3	977	0.061	0.1656	No
27	CNTNAP1	CNTNAP1	1061	0.059	0.1662	No
28	PODXL	PODXL	1273	0.055	0.1605	No
29	PTP4A3	PTP4A3	1283	0.055	0.1643	No
30	BIRC2	BIRC2	1360	0.053	0.1648	No
31	RELL1	RELL1	1411	0.053	0.1664	No
32	OSMR	OSMR	1457	0.052	0.1683	No
33	LRP2	LRP2	1595	0.050	0.1657	No
34	JUNB	JUNB	1660	0.049	0.1664	No
35	ZNF347	ZNF347	1670	0.049	0.1697	No
36	DACT1	DACT1	1729	0.048	0.1707	No
37	SOD2	SOD2	1797	0.047	0.1711	No
38	ARHGEF16	ARHGEF16	1823	0.047	0.1735	No
39	BCL6	BCL6	1952	0.045	0.1710	No
40	EFTUD2	EFTUD2	1964	0.045	0.1739	No
41	ZIK1	ZIK1	2021	0.044	0.1747	No
42	SEMA4B	SEMA4B	2149	0.043	0.1720	No
43	ZNF813	ZNF813	2157	0.043	0.1750	No
44	BCL3	BCL3	2307	0.041	0.1711	No
45	IFNGR1	IFNGR1	2319	0.041	0.1737	No
46	RGS16	RGS16	2391	0.040	0.1735	No
47	RPGR	RPGR	2459	0.040	0.1733	No
48	NCOA7	NCOA7	2485	0.039	0.1752	No
49	CRABP2	CRABP2	2885	0.036	0.1592	No
50	CLIC2	CLIC2	3052	0.035	0.1541	No
51	NUAK2	NUAK2	3103	0.034	0.1544	No
52	PTX3	PTX3	3107	0.034	0.1569	No
53	PDGFRL	PDGFRL	3174	0.034	0.1564	No
54	PEPD	PEPD	3273	0.033	0.1543	No
55	SFRP1	SFRP1	3395	0.032	0.1511	No
56	ADAMTS4	ADAMTS4	3421	0.032	0.1524	No
57	GTSF1	GTSF1	3504	0.031	0.1509	No
58	PGBD5	PGBD5	3513	0.031	0.1529	No
59	SNX10	SNX10	3515	0.031	0.1553	No
60	GRB10	GRB10	3563	0.031	0.1555	No
61	ADAMTS1	ADAMTS1	3635	0.031	0.1545	No
62	PMP22	PMP22	3640	0.031	0.1566	No
63	EBI3	EBI3	3755	0.030	0.1535	No
64	BATF3	BATF3	3760	0.030	0.1556	No
65	ZNF229	ZNF229	3771	0.030	0.1574	No
66	S100A10	S100A10	3782	0.030	0.1592	No
67	STAP2	STAP2	3798	0.029	0.1607	No
68	SYNGR3	SYNGR3	3890	0.029	0.1587	No
69	BACE2	BACE2	3897	0.029	0.1606	No
70	NAB2	NAB2	3904	0.029	0.1625	No
71	CDH4	CDH4	3939	0.029	0.1631	No
72	PLAT	PLAT	4053	0.028	0.1599	No
73	CREB3	CREB3	4238	0.027	0.1533	No
74	ZNF329	ZNF329	4295	0.026	0.1527	No
75	CD83	CD83	4319	0.026	0.1536	No
76	VAX1	VAX1	4322	0.026	0.1556	No
77	APOL6	APOL6	4528	0.025	0.1479	No
78	PRR16	PRR16	4546	0.025	0.1490	No
79	HAS2	HAS2	4692	0.024	0.1440	No
80	ZFP36	ZFP36	4748	0.024	0.1432	No
81	ELL2	ELL2	4749	0.024	0.1451	No
82	SGPP2	SGPP2	4856	0.023	0.1419	No
83	LIFR	LIFR	4928	0.023	0.1403	No
84	FJX1	FJX1	5024	0.022	0.1375	No
85	B2M	B2M	5076	0.022	0.1368	No
86	OPTN	OPTN	5205	0.022	0.1324	No
87	PSMD5	PSMD5	5228	0.021	0.1330	No
88	BMP5	BMP5	5262	0.021	0.1331	No
89	THY1	THY1	5296	0.021	0.1332	No
90	STOM	STOM	5826	0.019	0.1097	No
91	IL6ST	IL6ST	5931	0.018	0.1062	No
92	NPNT	NPNT	6054	0.017	0.1018	No
93	NR4A3	NR4A3	6451	0.016	0.0845	No
94	CSF1	CSF1	6684	0.015	0.0747	No
95	ZNF267	ZNF267	6876	0.014	0.0668	No
96	FZD8	FZD8	7021	0.013	0.0610	No
97	PCDH1	PCDH1	7051	0.013	0.0607	No
98	RBM3	RBM3	7375	0.012	0.0464	No
99	GABRA5	GABRA5	7431	0.012	0.0448	No
100	HLA-B	HLA-B	7810	0.010	0.0278	No
101	CYP1A1	CYP1A1	7889	0.010	0.0249	No
102	CDC42EP5	CDC42EP5	7999	0.010	0.0205	No
103	VWA1	VWA1	8282	0.009	0.0079	No
104	IL32	IL32	8306	0.008	0.0075	No
105	ZNF611	ZNF611	8319	0.008	0.0076	No
106	EMILIN2	EMILIN2	8526	0.008	-0.0015	No
107	CDKN2B	CDKN2B	8624	0.007	-0.0055	No
108	PARP9	PARP9	8752	0.007	-0.0109	No
109	PDGFA	PDGFA	9046	0.006	-0.0243	No
110	TSC22D4	TSC22D4	9139	0.006	-0.0282	No
111	ETV6	ETV6	9202	0.005	-0.0307	No
112	WIPF3	WIPF3	9336	0.005	-0.0365	No
113	ERAP1	ERAP1	9374	0.005	-0.0379	No
114	TMEM173	TMEM173	9450	0.004	-0.0411	No
115	CYP4V2	CYP4V2	9462	0.004	-0.0413	No
116	ORAI1	ORAI1	9567	0.004	-0.0459	No
117	MITD1	MITD1	9643	0.004	-0.0492	No
118	GCLM	GCLM	9716	0.003	-0.0523	No
119	SERPINA3	SERPINA3	10080	0.002	-0.0692	No
120	EGFLAM	EGFLAM	10147	0.002	-0.0721	No
121	IER2	IER2	10164	0.002	-0.0727	No
122	ZNF28	ZNF28	10202	0.002	-0.0743	No
123	NFE2L3	NFE2L3	10242	0.001	-0.0761	No
124	C1orf226	C1orf226	10309	0.001	-0.0791	No
125	KCNN4	KCNN4	10334	0.001	-0.0801	No
126	ITGAV	ITGAV	10370	0.001	-0.0817	No
127	NUDT4	NUDT4	10643	0.000	-0.0945	No
128	NFKBIZ	NFKBIZ	10728	-0.000	-0.0984	No
129	MGAT4B	MGAT4B	10778	-0.000	-0.1007	No
130	ASB9	ASB9	10841	-0.001	-0.1035	No
131	SPRED3	SPRED3	10899	-0.001	-0.1062	No
132	LHX9	LHX9	10908	-0.001	-0.1065	No
133	SORBS1	SORBS1	10911	-0.001	-0.1065	No
134	OSCP1	OSCP1	10914	-0.001	-0.1065	No
135	ZNF468	ZNF468	11024	-0.001	-0.1116	No
136	HLA-E	HLA-E	11037	-0.001	-0.1120	No
137	ACSL6	ACSL6	11065	-0.001	-0.1132	No
138	FOSL2	FOSL2	11178	-0.002	-0.1183	No
139	NFKB1	NFKB1	11278	-0.002	-0.1228	No
140	LPGAT1	LPGAT1	11369	-0.002	-0.1268	No
141	TNFRSF1A	TNFRSF1A	11380	-0.003	-0.1271	No
142	CARS	CARS	11438	-0.003	-0.1296	No
143	NRG1	NRG1	11523	-0.003	-0.1333	No
144	NR4A1	NR4A1	11625	-0.003	-0.1378	No
145	ARHGEF4	ARHGEF4	11675	-0.004	-0.1398	No
146	ANO9	ANO9	11713	-0.004	-0.1413	No
147	RAB31	RAB31	11737	-0.004	-0.1421	No
148	NTN1	NTN1	11776	-0.004	-0.1436	No
149	LRRC4B	LRRC4B	11821	-0.004	-0.1453	No
150	NDUFB8	NDUFB8	11831	-0.004	-0.1454	No
151	L1CAM	L1CAM	11912	-0.004	-0.1489	No
152	ALPL	ALPL	12058	-0.005	-0.1553	No
153	PIK3CD	PIK3CD	12129	-0.005	-0.1582	No
154	KLHL6	KLHL6	12204	-0.005	-0.1613	No
155	TRIM8	TRIM8	12222	-0.005	-0.1616	No
156	LGALS1	LGALS1	12490	-0.006	-0.1737	No
157	SGK1	SGK1	12551	-0.007	-0.1760	No
158	ZNF766	ZNF766	12637	-0.007	-0.1795	No
159	WWTR1	WWTR1	12641	-0.007	-0.1791	No
160	ZDHHC14	ZDHHC14	12666	-0.007	-0.1797	No
161	DOC2B	DOC2B	12953	-0.008	-0.1925	No
162	FGF2	FGF2	13179	-0.009	-0.2024	No
163	ZNF528	ZNF528	13265	-0.009	-0.2057	No
164	IFIH1	IFIH1	13292	-0.009	-0.2062	No
165	NFKB2	NFKB2	13329	-0.009	-0.2071	No
166	HIVEP1	HIVEP1	13411	-0.010	-0.2102	No
167	IRF3	IRF3	13414	-0.010	-0.2095	No
168	COL9A1	COL9A1	13493	-0.010	-0.2124	No
169	GAP43	GAP43	13780	-0.011	-0.2250	No
170	IL4I1	IL4I1	13781	-0.011	-0.2242	No
171	KLF10	KLF10	13829	-0.011	-0.2255	No
172	DUSP6	DUSP6	13939	-0.012	-0.2297	No
173	RELB	RELB	14022	-0.012	-0.2326	No
174	GABRB3	GABRB3	14334	-0.013	-0.2462	No
175	LIMD2	LIMD2	14364	-0.013	-0.2466	No
176	EMILIN1	EMILIN1	14486	-0.014	-0.2512	No
177	CITED4	CITED4	14506	-0.014	-0.2510	No
178	TAF13	TAF13	14634	-0.014	-0.2559	No
179	LOXL2	LOXL2	14726	-0.015	-0.2590	No
180	RHPN2	RHPN2	14785	-0.015	-0.2606	No
181	FAM43A	FAM43A	14824	-0.015	-0.2612	No
182	IFITM1	IFITM1	15019	-0.016	-0.2691	No
183	FADS3	FADS3	15104	-0.017	-0.2717	No
184	ZNF667	ZNF667	15111	-0.017	-0.2707	No
185	PLA2G4C	PLA2G4C	15113	-0.017	-0.2695	No
186	RGS3	RGS3	15170	-0.017	-0.2709	No
187	ENPP2	ENPP2	15253	-0.017	-0.2734	No
188	SMOC2	SMOC2	15346	-0.017	-0.2764	No
189	VDR	VDR	15499	-0.018	-0.2822	No
190	FAM174B	FAM174B	15521	-0.018	-0.2818	No
191	CA8	CA8	15603	-0.019	-0.2841	No
192	AHR	AHR	15846	-0.020	-0.2940	No
193	DPP4	DPP4	15849	-0.020	-0.2926	No
194	ALPK1	ALPK1	15888	-0.020	-0.2928	No
195	MYO5B	MYO5B	15898	-0.020	-0.2917	No
196	MAOB	MAOB	15939	-0.020	-0.2920	No
197	CTSS	CTSS	15988	-0.020	-0.2927	No
198	NRCAM	NRCAM	16138	-0.021	-0.2981	No
199	CAMK2D	CAMK2D	16390	-0.022	-0.3082	No
200	ETNK2	ETNK2	16452	-0.023	-0.3093	No
201	TNIP2	TNIP2	16539	-0.023	-0.3116	No
202	KIAA0040	KIAA0040	16549	-0.023	-0.3103	No
203	TNC	TNC	16569	-0.023	-0.3094	No
204	GFRA1	GFRA1	16618	-0.023	-0.3099	No
205	ADAMTS14	ADAMTS14	16661	-0.024	-0.3101	No
206	ARL6IP5	ARL6IP5	16696	-0.024	-0.3099	No
207	MGAT3	MGAT3	16883	-0.025	-0.3167	No
208	OSBPL5	OSBPL5	16892	-0.025	-0.3152	No
209	CYLD	CYLD	16905	-0.025	-0.3139	No
210	ZSWIM4	ZSWIM4	16916	-0.025	-0.3124	No
211	ROBO1	ROBO1	17097	-0.026	-0.3189	No
212	ICAM1	ICAM1	17117	-0.026	-0.3178	No
213	PGM2L1	PGM2L1	17386	-0.027	-0.3283	No
214	PNKD	PNKD	17390	-0.027	-0.3263	No
215	TAPBP	TAPBP	17481	-0.028	-0.3284	No
216	PERP	PERP	17526	-0.028	-0.3283	No
217	RIPK1	RIPK1	18029	-0.031	-0.3495	No
218	ABR	ABR	18044	-0.031	-0.3478	No
219	SYT12	SYT12	18143	-0.032	-0.3500	No
220	RASEF	RASEF	18160	-0.032	-0.3483	No
221	PTPRE	PTPRE	18369	-0.033	-0.3555	No
222	PLEKHA4	PLEKHA4	18474	-0.034	-0.3578	No
223	C10orf90	C10orf90	18542	-0.035	-0.3582	Yes
224	MICALL2	MICALL2	18568	-0.035	-0.3567	Yes
225	TGFB1	TGFB1	18625	-0.035	-0.3567	Yes
226	PLLP	PLLP	18644	-0.036	-0.3548	Yes
227	NFKBIA	NFKBIA	18697	-0.036	-0.3545	Yes
228	ADAM19	ADAM19	18801	-0.037	-0.3565	Yes
229	RNF145	RNF145	18808	-0.037	-0.3539	Yes
230	GRWD1	GRWD1	18842	-0.037	-0.3526	Yes
231	BMP2	BMP2	18843	-0.037	-0.3498	Yes
232	DTX3L	DTX3L	19022	-0.039	-0.3552	Yes
233	SEMA3B	SEMA3B	19064	-0.039	-0.3541	Yes
234	SYNPO	SYNPO	19198	-0.041	-0.3573	Yes
235	APBA1	APBA1	19206	-0.041	-0.3545	Yes
236	TIFA	TIFA	19209	-0.041	-0.3515	Yes
237	IL27RA	IL27RA	19221	-0.041	-0.3489	Yes
238	TBC1D10A	TBC1D10A	19226	-0.041	-0.3459	Yes
239	RAB35	RAB35	19240	-0.041	-0.3434	Yes
240	C1orf198	C1orf198	19498	-0.043	-0.3521	Yes
241	ZNF701	ZNF701	19514	-0.044	-0.3495	Yes
242	TAGLN2	TAGLN2	19565	-0.044	-0.3485	Yes
243	CXCL10	CXCL10	19596	-0.045	-0.3465	Yes
244	KREMEN2	KREMEN2	19663	-0.045	-0.3461	Yes
245	TMEM151B	TMEM151B	19693	-0.046	-0.3439	Yes
246	UGCG	UGCG	19783	-0.047	-0.3445	Yes
247	EMP3	EMP3	19792	-0.047	-0.3413	Yes
248	TRAF1	TRAF1	19832	-0.048	-0.3395	Yes
249	ZBED1	ZBED1	19862	-0.048	-0.3372	Yes
250	FAM131B	FAM131B	19876	-0.048	-0.3341	Yes
251	TMEM158	TMEM158	19929	-0.049	-0.3328	Yes
252	IGFBP3	IGFBP3	19998	-0.050	-0.3322	Yes
253	CLDN4	CLDN4	20006	-0.050	-0.3287	Yes
254	CITED1	CITED1	20119	-0.051	-0.3300	Yes
255	LARP6	LARP6	20168	-0.052	-0.3283	Yes
256	MAP3K11	MAP3K11	20212	-0.053	-0.3263	Yes
257	CABLES1	CABLES1	20336	-0.055	-0.3278	Yes
258	PLCD3	PLCD3	20398	-0.056	-0.3264	Yes
259	IFNGR2	IFNGR2	20399	-0.056	-0.3221	Yes
260	CD63	CD63	20414	-0.056	-0.3184	Yes
261	NFKBIE	NFKBIE	20540	-0.059	-0.3198	Yes
262	PLEKHF1	PLEKHF1	20606	-0.061	-0.3182	Yes
263	TRPM8	TRPM8	20649	-0.062	-0.3154	Yes
264	SQSTM1	SQSTM1	20653	-0.062	-0.3108	Yes
265	LAPTM5	LAPTM5	20687	-0.063	-0.3076	Yes
266	RRAS	RRAS	20702	-0.064	-0.3034	Yes
267	AGT	AGT	20709	-0.064	-0.2988	Yes
268	FAM129A	FAM129A	20817	-0.067	-0.2987	Yes
269	RAB13	RAB13	20830	-0.067	-0.2941	Yes
270	ARNTL2	ARNTL2	20855	-0.068	-0.2900	Yes
271	ADAMTS9	ADAMTS9	20954	-0.071	-0.2892	Yes
272	CDKN1A	CDKN1A	20989	-0.072	-0.2853	Yes
273	TIMP1	TIMP1	21029	-0.074	-0.2814	Yes
274	SERTAD1	SERTAD1	21172	-0.081	-0.2819	Yes
275	CAPN5	CAPN5	21192	-0.083	-0.2765	Yes
276	DRAM1	DRAM1	21232	-0.086	-0.2717	Yes
277	ASPHD1	ASPHD1	21242	-0.086	-0.2656	Yes
278	IRAK2	IRAK2	21246	-0.087	-0.2591	Yes
279	NBL1	NBL1	21269	-0.088	-0.2534	Yes
280	PRICKLE1	PRICKLE1	21280	-0.089	-0.2471	Yes
281	CEBPB	CEBPB	21289	-0.090	-0.2406	Yes
282	SH2B3	SH2B3	21319	-0.093	-0.2348	Yes
283	EGR2	EGR2	21344	-0.097	-0.2286	Yes
284	LIF	LIF	21404	-0.105	-0.2233	Yes
285	LRRN3	LRRN3	21411	-0.106	-0.2155	Yes
286	WARS	WARS	21449	-0.112	-0.2087	Yes
287	IRF1	IRF1	21459	-0.115	-0.2003	Yes
288	IER3	IER3	21480	-0.122	-0.1919	Yes
289	SPP1	SPP1	21488	-0.124	-0.1827	Yes
290	SDC4	SDC4	21489	-0.125	-0.1732	Yes
291	TNFAIP3	TNFAIP3	21499	-0.132	-0.1636	Yes
292	PLAU	PLAU	21507	-0.141	-0.1531	Yes
293	HMOX1	HMOX1	21512	-0.144	-0.1423	Yes
294	EMP1	EMP1	21515	-0.145	-0.1313	Yes
295	SPSB1	SPSB1	21516	-0.145	-0.1202	Yes
296	AHNAK2	AHNAK2	21523	-0.148	-0.1092	Yes
297	TNFRSF12A	TNFRSF12A	21534	-0.154	-0.0979	Yes
298	ISG20	ISG20	21547	-0.169	-0.0855	Yes
299	RNF19A	RNF19A	21550	-0.172	-0.0725	Yes
300	SERPINE1	SERPINE1	21554	-0.173	-0.0594	Yes
301	VGF	VGF	21563	-0.182	-0.0458	Yes
302	CHI3L1	CHI3L1	21572	-0.194	-0.0314	Yes
303	RDH10	RDH10	21576	-0.204	-0.0159	Yes
304	DUSP5	DUSP5	21581	-0.219	0.0007	Yes