Details for gene set SCHMITT_HMG

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	SCHMITT_HMG_2020
Enrichment Score (ES)	-0.30534154
Normalized Enrichment Score (NES)	-1.4367709
Nominal p-value	0.002008032
FDR q-value	0.03409353
FWER p-Value	0.299

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PMP2	PMP2	15	0.222	0.0193	No
2	A2M	A2M	36	0.168	0.0335	No
3	KLF6	KLF6	97	0.128	0.0423	No
4	C1S	C1S	115	0.117	0.0521	No
5	C12orf76	C12orf76	118	0.116	0.0625	No
6	ZNF608	ZNF608	125	0.113	0.0724	No
7	FBXO32	FBXO32	131	0.111	0.0822	No
8	NEDD9	NEDD9	136	0.111	0.0920	No
9	TBC1D23	TBC1D23	164	0.106	0.1003	No
10	SYNM	SYNM	168	0.105	0.1097	No
11	FZD5	FZD5	235	0.096	0.1152	No
12	MATN2	MATN2	265	0.093	0.1222	No
13	CD44	CD44	281	0.092	0.1298	No
14	TPST1	TPST1	285	0.092	0.1379	No
15	ATCAY	ATCAY	286	0.092	0.1462	No
16	NAMPT	NAMPT	433	0.081	0.1466	No
17	TBC1D15	TBC1D15	449	0.080	0.1532	No
18	SOCS3	SOCS3	538	0.076	0.1559	No
19	LIPG	LIPG	629	0.072	0.1582	No
20	FUT1	FUT1	673	0.070	0.1625	No
21	FMN2	FMN2	736	0.068	0.1658	No
22	F3	F3	837	0.065	0.1669	No
23	CBWD5	CBWD5	874	0.064	0.1710	No
24	PTCHD1	PTCHD1	940	0.062	0.1735	No
25	C4A	C4A	968	0.061	0.1778	No
26	SLC2A3	SLC2A3	977	0.061	0.1829	No
27	EPHX1	EPHX1	988	0.061	0.1880	No
28	CIR1	CIR1	1002	0.060	0.1928	No
29	GPR107	GPR107	1062	0.059	0.1954	No
30	YPEL2	YPEL2	1121	0.058	0.1979	No
31	LONRF1	LONRF1	1199	0.057	0.1994	No
32	STK19	STK19	1247	0.056	0.2022	No
33	PODXL	PODXL	1273	0.055	0.2060	No
34	PTP4A3	PTP4A3	1283	0.055	0.2106	No
35	COG6	COG6	1296	0.055	0.2149	No
36	OSMR	OSMR	1457	0.052	0.2121	No
37	CRYAB	CRYAB	1460	0.052	0.2167	No
38	DBP	DBP	1538	0.051	0.2176	No
39	UFM1	UFM1	1675	0.049	0.2157	No
40	RPE65	RPE65	1945	0.045	0.2071	No
41	BCL6	BCL6	1952	0.045	0.2109	No
42	SEMA4B	SEMA4B	2149	0.043	0.2056	No
43	HABP4	HABP4	2236	0.042	0.2054	No
44	EFNA1	EFNA1	2376	0.040	0.2025	No
45	RGS16	RGS16	2391	0.040	0.2055	No
46	TXNIP	TXNIP	2509	0.039	0.2035	No
47	YPEL3	YPEL3	2592	0.039	0.2032	No
48	YOD1	YOD1	2855	0.036	0.1942	No
49	CLIC2	CLIC2	3052	0.035	0.1881	No
50	PDP2	PDP2	3055	0.035	0.1912	No
51	NUAK2	NUAK2	3103	0.034	0.1921	No
52	SYDE2	SYDE2	3200	0.034	0.1906	No
53	C1QL1	C1QL1	3268	0.033	0.1905	No
54	MYCN	MYCN	3326	0.033	0.1908	No
55	SNX10	SNX10	3515	0.031	0.1848	No
56	RAB4A	RAB4A	3630	0.031	0.1822	No
57	PMP22	PMP22	3640	0.031	0.1846	No
58	PIKFYVE	PIKFYVE	3661	0.030	0.1864	No
59	ATP1B2	ATP1B2	3756	0.030	0.1846	No
60	S100A10	S100A10	3782	0.030	0.1861	No
61	HMGCS1	HMGCS1	3917	0.029	0.1824	No
62	ZBTB41	ZBTB41	3980	0.028	0.1821	No
63	LGMN	LGMN	4008	0.028	0.1834	No
64	ARF4	ARF4	4023	0.028	0.1852	No
65	PITPNC1	PITPNC1	4196	0.027	0.1796	No
66	MERTK	MERTK	4235	0.027	0.1802	No
67	APOL6	APOL6	4528	0.025	0.1688	No
68	TCP11L2	TCP11L2	4576	0.025	0.1689	No
69	ARRDC3	ARRDC3	4616	0.025	0.1692	No
70	IL13RA1	IL13RA1	4625	0.025	0.1711	No
71	ZFP36	ZFP36	4748	0.024	0.1675	No
72	INSIG1	INSIG1	4796	0.023	0.1674	No
73	SEC14L1	SEC14L1	4877	0.023	0.1658	No
74	ARMCX1	ARMCX1	4886	0.023	0.1675	No
75	LIFR	LIFR	4928	0.023	0.1676	No
76	PRICKLE2	PRICKLE2	4947	0.023	0.1688	No
77	PJA2	PJA2	5193	0.022	0.1593	No
78	BMP5	BMP5	5262	0.021	0.1580	No
79	CYB561D2	CYB561D2	5400	0.021	0.1534	No
80	GOLGA3	GOLGA3	5596	0.020	0.1460	No
81	BCAM	BCAM	5767	0.019	0.1398	No
82	SLC30A5	SLC30A5	5788	0.019	0.1405	No
83	GPR20	GPR20	5880	0.018	0.1379	No
84	TTC39B	TTC39B	5975	0.018	0.1351	No
85	FAM114A1	FAM114A1	6037	0.018	0.1338	No
86	CLU	CLU	6086	0.017	0.1331	No
87	MAFF	MAFF	6367	0.016	0.1215	No
88	MAP3K6	MAP3K6	6418	0.016	0.1206	No
89	NR4A3	NR4A3	6451	0.016	0.1205	No
90	GOLGA5	GOLGA5	6600	0.015	0.1149	No
91	ZFP28	ZFP28	6662	0.015	0.1134	No
92	EDEM3	EDEM3	6670	0.015	0.1144	No
93	CSF1	CSF1	6684	0.015	0.1151	No
94	GOLGA4	GOLGA4	6735	0.015	0.1141	No
95	TAF1D	TAF1D	6778	0.014	0.1134	No
96	FGFBP3	FGFBP3	6933	0.014	0.1074	No
97	USP51	USP51	7060	0.013	0.1027	No
98	ARID5A	ARID5A	7438	0.012	0.0861	No
99	KCNA4	KCNA4	7449	0.012	0.0867	No
100	ABHD4	ABHD4	7525	0.011	0.0842	No
101	ZFPL1	ZFPL1	7551	0.011	0.0840	No
102	SLC16A4	SLC16A4	7741	0.011	0.0761	No
103	ATG9B	ATG9B	7873	0.010	0.0709	No
104	SYN3	SYN3	7920	0.010	0.0697	No
105	GDA	GDA	7957	0.010	0.0688	No
106	ITGA10	ITGA10	8067	0.009	0.0646	No
107	DCDC2	DCDC2	8165	0.009	0.0608	No
108	POLR3D	POLR3D	8357	0.008	0.0526	No
109	IRF9	IRF9	8540	0.008	0.0448	No
110	PFKFB2	PFKFB2	8821	0.007	0.0322	No
111	PIM1	PIM1	8834	0.006	0.0323	No
112	DCAF4L1	DCAF4L1	8953	0.006	0.0273	No
113	JAG2	JAG2	9080	0.006	0.0219	No
114	COL11A2	COL11A2	9133	0.006	0.0200	No
115	SH3BP5	SH3BP5	9184	0.005	0.0181	No
116	MEIS3	MEIS3	9284	0.005	0.0139	No
117	TMEM173	TMEM173	9450	0.004	0.0065	No
118	VASH2	VASH2	9532	0.004	0.0031	No
119	FTL	FTL	9543	0.004	0.0030	No
120	GRIK1	GRIK1	9586	0.004	0.0014	No
121	ANXA11	ANXA11	9600	0.004	0.0011	No
122	PPP2R5A	PPP2R5A	9841	0.003	-0.0099	No
123	IL6R	IL6R	9881	0.003	-0.0115	No
124	SERPINA3	SERPINA3	10080	0.002	-0.0206	No
125	C1orf162	C1orf162	10186	0.002	-0.0254	No
126	ZBTB46	ZBTB46	10279	0.001	-0.0296	No
127	RPL37A	RPL37A	10290	0.001	-0.0299	No
128	COL6A1	COL6A1	10351	0.001	-0.0326	No
129	COL6A2	COL6A2	10417	0.001	-0.0356	No
130	PDK4	PDK4	10548	0.000	-0.0417	No
131	TSC22D3	TSC22D3	10720	-0.000	-0.0497	No
132	CHN2	CHN2	10836	-0.001	-0.0550	No
133	LHX9	LHX9	10908	-0.001	-0.0583	No
134	MKNK1	MKNK1	10976	-0.001	-0.0613	No
135	HLA-E	HLA-E	11037	-0.001	-0.0640	No
136	ACSL6	ACSL6	11065	-0.001	-0.0652	No
137	ACBD3	ACBD3	11309	-0.002	-0.0764	No
138	IL21R	IL21R	11345	-0.002	-0.0778	No
139	ATF3	ATF3	11356	-0.002	-0.0780	No
140	TNFRSF1A	TNFRSF1A	11380	-0.003	-0.0789	No
141	PDE4DIP	PDE4DIP	11426	-0.003	-0.0808	No
142	FGD4	FGD4	11560	-0.003	-0.0867	No
143	YIPF2	YIPF2	11568	-0.003	-0.0868	No
144	GOLT1B	GOLT1B	11639	-0.003	-0.0897	No
145	TRIM7	TRIM7	11789	-0.004	-0.0964	No
146	ACSS2	ACSS2	11798	-0.004	-0.0964	No
147	RAB5A	RAB5A	11854	-0.004	-0.0986	No
148	NUPR1	NUPR1	11883	-0.004	-0.0995	No
149	TMEM87B	TMEM87B	11889	-0.004	-0.0994	No
150	IDI1	IDI1	12013	-0.005	-0.1047	No
151	ITGA11	ITGA11	12108	-0.005	-0.1087	No
152	TMEM231	TMEM231	12228	-0.005	-0.1138	No
153	SGK1	SGK1	12551	-0.007	-0.1283	No
154	ULBP2	ULBP2	12567	-0.007	-0.1284	No
155	TMEM50B	TMEM50B	12622	-0.007	-0.1303	No
156	SPTB	SPTB	12682	-0.007	-0.1324	No
157	KCNK10	KCNK10	12828	-0.008	-0.1385	No
158	TMEM97	TMEM97	12999	-0.008	-0.1458	No
159	PDXDC1	PDXDC1	13092	-0.009	-0.1493	No
160	PLSCR4	PLSCR4	13134	-0.009	-0.1504	No
161	RAB3B	RAB3B	13316	-0.009	-0.1581	No
162	ABCD2	ABCD2	13424	-0.010	-0.1622	No
163	APOL2	APOL2	13712	-0.011	-0.1747	No
164	CRELD1	CRELD1	13725	-0.011	-0.1743	No
165	GOSR2	GOSR2	13727	-0.011	-0.1733	No
166	GJA3	GJA3	13863	-0.011	-0.1786	No
167	MTUS1	MTUS1	14054	-0.012	-0.1864	No
168	SPTY2D1	SPTY2D1	14111	-0.013	-0.1879	No
169	CIB1	CIB1	14116	-0.013	-0.1870	No
170	NPC2	NPC2	14183	-0.013	-0.1889	No
171	GOLGB1	GOLGB1	14237	-0.013	-0.1902	No
172	ACAN	ACAN	14358	-0.013	-0.1946	No
173	EPHA5	EPHA5	14371	-0.013	-0.1940	No
174	GOLGA2	GOLGA2	14378	-0.014	-0.1930	No
175	KLF9	KLF9	14521	-0.014	-0.1984	No
176	SYCP2	SYCP2	14692	-0.015	-0.2051	No
177	IFITM1	IFITM1	15019	-0.016	-0.2189	No
178	PLA2G4C	PLA2G4C	15113	-0.017	-0.2218	No
179	NDRG2	NDRG2	15120	-0.017	-0.2206	No
180	RGS3	RGS3	15170	-0.017	-0.2213	No
181	AKNA	AKNA	15224	-0.017	-0.2223	No
182	LYST	LYST	15231	-0.017	-0.2210	No
183	PPM1K	PPM1K	15370	-0.018	-0.2259	No
184	N4BP2L1	N4BP2L1	15404	-0.018	-0.2259	No
185	VMAC	VMAC	15558	-0.018	-0.2314	No
186	RUNX1T1	RUNX1T1	15645	-0.019	-0.2337	No
187	ALPK1	ALPK1	15888	-0.020	-0.2433	No
188	MYO5B	MYO5B	15898	-0.020	-0.2419	No
189	NRCAM	NRCAM	16138	-0.021	-0.2512	No
190	COL14A1	COL14A1	16208	-0.021	-0.2525	No
191	BCYRN1	BCYRN1	16312	-0.022	-0.2553	No
192	FABP3	FABP3	16361	-0.022	-0.2556	No
193	CAMK2D	CAMK2D	16390	-0.022	-0.2549	No
194	CISH	CISH	16396	-0.022	-0.2531	No
195	MOSPD1	MOSPD1	16479	-0.023	-0.2549	No
196	KIAA0040	KIAA0040	16549	-0.023	-0.2561	No
197	TNC	TNC	16569	-0.023	-0.2549	No
198	HDAC9	HDAC9	16598	-0.023	-0.2541	No
199	GLIS3	GLIS3	16600	-0.023	-0.2521	No
200	PTGES	PTGES	16673	-0.024	-0.2533	No
201	TMCC3	TMCC3	16823	-0.024	-0.2581	No
202	ANKRD20A4	ANKRD20A4	17071	-0.026	-0.2674	No
203	ICAM1	ICAM1	17117	-0.026	-0.2671	No
204	GREM2	GREM2	17223	-0.027	-0.2697	No
205	PGM2L1	PGM2L1	17386	-0.027	-0.2748	No
206	DDR1	DDR1	17762	-0.029	-0.2897	No
207	CCDC113	CCDC113	17909	-0.030	-0.2938	No
208	GADD45A	GADD45A	17924	-0.030	-0.2917	No
209	TMEM120A	TMEM120A	18185	-0.032	-0.3010	No
210	CBX7	CBX7	18278	-0.033	-0.3024	Yes
211	FSTL5	FSTL5	18308	-0.033	-0.3008	Yes
212	MVP	MVP	18318	-0.033	-0.2982	Yes
213	C9orf72	C9orf72	18425	-0.034	-0.3001	Yes
214	PROS1	PROS1	18515	-0.035	-0.3011	Yes
215	CDKL3	CDKL3	18574	-0.035	-0.3007	Yes
216	DGKI	DGKI	18589	-0.035	-0.2982	Yes
217	LIN7A	LIN7A	18595	-0.035	-0.2952	Yes
218	MALT1	MALT1	18604	-0.035	-0.2924	Yes
219	IFITM2	IFITM2	18618	-0.035	-0.2898	Yes
220	DNHD1	DNHD1	18657	-0.036	-0.2884	Yes
221	PORCN	PORCN	18766	-0.037	-0.2901	Yes
222	BST2	BST2	18775	-0.037	-0.2872	Yes
223	AOC2	AOC2	18782	-0.037	-0.2842	Yes
224	PMM2	PMM2	18829	-0.037	-0.2830	Yes
225	DTX3L	DTX3L	19022	-0.039	-0.2885	Yes
226	PIK3IP1	PIK3IP1	19025	-0.039	-0.2851	Yes
227	GCNT4	GCNT4	19062	-0.039	-0.2832	Yes
228	ENO3	ENO3	19107	-0.040	-0.2817	Yes
229	KDELR3	KDELR3	19172	-0.040	-0.2811	Yes
230	LMAN1	LMAN1	19532	-0.044	-0.2939	Yes
231	SLC26A2	SLC26A2	19546	-0.044	-0.2906	Yes
232	TAGLN2	TAGLN2	19565	-0.044	-0.2874	Yes
233	JAK3	JAK3	19570	-0.044	-0.2836	Yes
234	SLC2A4	SLC2A4	19617	-0.045	-0.2817	Yes
235	CBS	CBS	19684	-0.046	-0.2807	Yes
236	EIF2AK3	EIF2AK3	19733	-0.046	-0.2787	Yes
237	DNAJB5	DNAJB5	19743	-0.046	-0.2750	Yes
238	EML2	EML2	19805	-0.047	-0.2736	Yes
239	TRAF1	TRAF1	19832	-0.048	-0.2705	Yes
240	CLDN4	CLDN4	20006	-0.050	-0.2741	Yes
241	CITED1	CITED1	20119	-0.051	-0.2747	Yes
242	GBP2	GBP2	20133	-0.052	-0.2707	Yes
243	CRTAP	CRTAP	20159	-0.052	-0.2671	Yes
244	HSD3B7	HSD3B7	20165	-0.052	-0.2627	Yes
245	CLIP2	CLIP2	20211	-0.053	-0.2600	Yes
246	SRPX	SRPX	20571	-0.060	-0.2714	Yes
247	TRPM8	TRPM8	20649	-0.062	-0.2695	Yes
248	LAPTM5	LAPTM5	20687	-0.063	-0.2655	Yes
249	AGT	AGT	20709	-0.064	-0.2607	Yes
250	MCEE	MCEE	20710	-0.064	-0.2550	Yes
251	CCNG1	CCNG1	20744	-0.064	-0.2507	Yes
252	EEPD1	EEPD1	20815	-0.067	-0.2479	Yes
253	GLRX	GLRX	20844	-0.068	-0.2431	Yes
254	AHNAK	AHNAK	20906	-0.070	-0.2397	Yes
255	SPARC	SPARC	20960	-0.071	-0.2358	Yes
256	CDKN1A	CDKN1A	20989	-0.072	-0.2305	Yes
257	TIMP1	TIMP1	21029	-0.074	-0.2257	Yes
258	PDGFRB	PDGFRB	21109	-0.078	-0.2224	Yes
259	CCNB1IP1	CCNB1IP1	21183	-0.082	-0.2184	Yes
260	PKIG	PKIG	21205	-0.084	-0.2118	Yes
261	GPX3	GPX3	21217	-0.085	-0.2047	Yes
262	SLC22A18	SLC22A18	21336	-0.096	-0.2016	Yes
263	MAN2A1	MAN2A1	21374	-0.101	-0.1942	Yes
264	LDLR	LDLR	21410	-0.105	-0.1864	Yes
265	WIPI1	WIPI1	21433	-0.109	-0.1776	Yes
266	RCN3	RCN3	21446	-0.111	-0.1681	Yes
267	EMP1	EMP1	21515	-0.145	-0.1582	Yes
268	AHNAK2	AHNAK2	21523	-0.148	-0.1451	Yes
269	ISG20	ISG20	21547	-0.169	-0.1310	Yes
270	SERPINE1	SERPINE1	21554	-0.173	-0.1156	Yes
271	VGF	VGF	21563	-0.182	-0.0995	Yes
272	CHI3L1	CHI3L1	21572	-0.194	-0.0824	Yes
273	RDH10	RDH10	21576	-0.204	-0.0641	Yes
274	DUSP5	DUSP5	21581	-0.219	-0.0445	Yes
275	THBS2	THBS2	21584	-0.228	-0.0241	Yes
276	APOE	APOE	21593	-0.272	0.0001	Yes