DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetSALL2_REGULON
Enrichment Score (ES)0.2837111
Normalized Enrichment Score (NES)1.1333504
Nominal p-value0.23265307
FDR q-value0.25941712
FWER p-Value0.966
Table: GSEA Results Summary



Fig 1: Enrichment plot: SALL2_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1AGPAT5AGPAT5540.1480.0426Yes
2JAM2JAM21120.1180.0759Yes
3CTNND2CTNND21420.1090.1078Yes
4MAP2MAP21450.1080.1406Yes
5FZD3FZD34250.0810.1523Yes
6NOTCH3NOTCH38120.0650.1542Yes
7STARD7STARD79850.0610.1647Yes
8MT3MT310200.0600.1814Yes
9SNX7SNX712030.0560.1901Yes
10NLGN3NLGN313760.0530.1982Yes
11MARCKSL1MARCKSL115000.0510.2081Yes
12TRIM24TRIM2416260.0490.2173Yes
13TTYH1TTYH116430.0490.2315Yes
14KIF2AKIF2A17560.0480.2408Yes
15OSTF1OSTF119200.0460.2471Yes
16CEP68CEP6822750.0420.2433Yes
17DHTKD1DHTKD122890.0410.2552Yes
18SEC61A2SEC61A224690.0400.2589Yes
19ZNF219ZNF21925820.0390.2655Yes
20RASSF2RASSF225950.0390.2766Yes
21ARNT2ARNT226910.0380.2837Yes
22FXYD5FXYD533440.0330.2633No
23ATP1B2ATP1B237560.0300.2532No
24RPL39LRPL39L39810.0280.2514No
25TBC1D8BTBC1D8B41640.0270.2512No
26POMT2POMT245730.0250.2398No
27PCM1PCM149500.0230.2292No
28LLGL1LLGL149770.0230.2349No
29ADAMTS3ADAMTS351290.0220.2345No
30DTX3DTX352630.0210.2348No
31APBA2APBA253940.0210.2350No
32CHD7CHD760150.0180.2115No
33RAB8BRAB8B63100.0160.2028No
34SLC22A17SLC22A1771650.0130.1670No
35PHLPP1PHLPP175980.0110.1503No
36GAL3ST4GAL3ST478860.0100.1400No
37CDC42BPBCDC42BPB81800.0090.1291No
38COPB2COPB287020.0070.1070No
39IL17RBIL17RB90670.0060.0918No
40TANC2TANC295270.0040.0717No
41SGSM2SGSM297030.0030.0646No
42DICER1DICER199350.0030.0546No
43ASCL1ASCL1102710.0010.0395No
44MED8MED810755-0.0000.0171No
45EFNB3EFNB310969-0.0010.0075No
46ZHX2ZHX211575-0.003-0.0197No
47NOVA1NOVA111602-0.003-0.0199No
48BAG5BAG511634-0.003-0.0203No
49KIF1BKIF1B11819-0.004-0.0276No
50ACSBG1ACSBG112021-0.005-0.0356No
51DENND5ADENND5A12040-0.005-0.0350No
52EVLEVL12208-0.005-0.0411No
53NTAN1NTAN112749-0.007-0.0640No
54CHD8CHD812896-0.008-0.0684No
55WNT11WNT1112964-0.008-0.0690No
56TARBP1TARBP113104-0.009-0.0729No
57PTGS2PTGS213295-0.009-0.0789No
58AGRNAGRN13386-0.010-0.0801No
59SOX4SOX413444-0.010-0.0797No
60ZFP30ZFP3013877-0.012-0.0963No
61VASH1VASH114254-0.013-0.1099No
62PCP4PCP414265-0.013-0.1063No
63ZMYM2ZMYM214316-0.013-0.1046No
64YKT6YKT614560-0.014-0.1116No
65DIP2CDIP2C14830-0.015-0.1195No
66CKBCKB15032-0.016-0.1239No
67PDCD6IPPDCD6IP15839-0.020-0.1553No
68KLKL16020-0.021-0.1575No
69NPAS3NPAS316347-0.022-0.1659No
70FLRT3FLRT316911-0.025-0.1846No
71CASP4CASP417111-0.026-0.1859No
72ALDH6A1ALDH6A117804-0.030-0.2091No
73NCANNCAN17822-0.030-0.2008No
74TRAPPC3TRAPPC318516-0.035-0.2225No
75MYLKMYLK18526-0.035-0.2124No
76PLXNA2PLXNA218553-0.035-0.2030No
77GLRX2GLRX219020-0.039-0.2128No
78LMNALMNA19085-0.039-0.2038No
79ENPP1ENPP119331-0.042-0.2025No
80SEMA6ASEMA6A19784-0.047-0.2093No
81PAQR6PAQR620364-0.056-0.2193No
82MSI1MSI120727-0.064-0.2166No
83ZNF629ZNF62920767-0.065-0.1986No
84RNFT2RNFT220811-0.067-0.1804No
85MEF2DMEF2D21021-0.074-0.1677No
86ARPC1BARPC1B21177-0.082-0.1500No
87PLP2PLP221203-0.083-0.1258No
88MICAL2MICAL221308-0.091-0.1029No
89PROCRPROCR21321-0.093-0.0750No
90STX3STX321399-0.104-0.0469No
91RIN2RIN221566-0.1840.0013No
Table: GSEA details [plain text format]



Fig 2: SALL2_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SALL2_REGULON: Random ES distribution   
Gene set null distribution of ES for SALL2_REGULON