DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetPHILLIPS_PROLIFERATIVE_2006
Enrichment Score (ES)0.2944577
Normalized Enrichment Score (NES)1.2969382
Nominal p-value0.040567953
FDR q-value0.10944437
FWER p-Value0.657
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_PROLIFERATIVE_2006   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1RRM2RRM2630.1430.0243Yes
2CREBZFCREBZF1790.1030.0386Yes
3MAD2L1MAD2L12020.1000.0567Yes
4WEE1WEE13110.0890.0686Yes
5CDCA7CDCA73120.0890.0856Yes
6PEG10PEG103810.0830.0984Yes
7SMC2SMC24260.0810.1118Yes
8PCNAPCNA4320.0810.1270Yes
9ABHD3ABHD34520.0800.1414Yes
10MNS1MNS14870.0780.1547Yes
11TMEM14BTMEM14B5400.0760.1668Yes
12PAIP1PAIP17540.0670.1697Yes
13TOM1L1TOM1L17780.0670.1814Yes
14C3orf14C3orf148940.0630.1881Yes
15CENPKCENPK11840.0570.1854Yes
16CDKN2CCDKN2C14960.0510.1807Yes
17ACN9ACN915890.0500.1859Yes
18DBF4DBF415930.0500.1953Yes
19MCM2MCM216490.0490.2021Yes
20FBXO5FBXO517780.0470.2052Yes
21GGHGGH18250.0470.2119Yes
22YEATS4YEATS418430.0460.2200Yes
23ANKRD32ANKRD3220500.0440.2188Yes
24DONSONDONSON21320.0430.2233Yes
25KIAA0101KIAA010121650.0430.2300Yes
26EZH2EZH221910.0430.2369Yes
27GINS1GINS122080.0420.2443Yes
28LRIG3LRIG322270.0420.2514Yes
29CHEK1CHEK122400.0420.2589Yes
30CENPLCENPL23020.0410.2639Yes
31TOP2ATOP2A23710.0400.2684Yes
32KNTC1KNTC124900.0390.2704Yes
33TCF19TCF1925610.0390.2746Yes
34MND1MND125760.0390.2813Yes
35PPIGPPIG26850.0380.2835Yes
36FANCIFANCI28600.0360.2823Yes
37CEP152CEP15230430.0350.2805Yes
38CDK2CDK231580.0340.2817Yes
39XRCC4XRCC431870.0340.2868Yes
40GINS2GINS232290.0330.2913Yes
41ITGA2ITGA232970.0330.2945Yes
42PLK4PLK436840.0300.2822No
43CCNA2CCNA241560.0270.2654No
44LMNB1LMNB141740.0270.2698No
45ZWILCHZWILCH42540.0270.2712No
46TEX9TEX942580.0270.2762No
47NPHP1NPHP143840.0260.2753No
48RFC4RFC446220.0250.2689No
49MELKMELK47750.0240.2663No
50DSN1DSN149860.0230.2608No
51CDC6CDC650670.0220.2613No
52ATG12ATG1254500.0200.2474No
53PABPC4LPABPC4L54650.0200.2506No
54TRMT6TRMT655140.0200.2522No
55TTKTTK55900.0200.2524No
56CENPACENPA57480.0190.2487No
57TTC12TTC1257810.0190.2507No
58USP1USP158540.0180.2509No
59CDC25CCDC25C62380.0170.2362No
60HMGB2HMGB262850.0170.2372No
61RRM1RRM163500.0160.2373No
62CCDC34CCDC3463580.0160.2401No
63ORC6LORC6L63910.0160.2417No
64SHFM1SHFM165650.0150.2365No
65NASPNASP68330.0140.2267No
66KIF4AKIF4A68890.0140.2268No
67RAD51AP1RAD51AP170250.0130.2231No
68GJC1GJC171720.0130.2187No
69MLF1MLF174910.0120.2060No
70SLC25A24SLC25A2475650.0110.2048No
71MLF1IPMLF1IP77110.0110.2000No
72DHFRDHFR78010.0100.1979No
73CENPICENPI78590.0100.1972No
74RBBP8RBBP878620.0100.1990No
75SMC4SMC479510.0100.1968No
76KIF23KIF2380570.0090.1937No
77TTC26TTC2681890.0090.1893No
78MAGOHBMAGOHB85800.0080.1725No
79BARD1BARD186680.0070.1698No
80C3orf34C3orf3488030.0070.1648No
81MDFICMDFIC88220.0070.1652No
82PPIL5PPIL588330.0070.1660No
83RPA3RPA389850.0060.1601No
84HELLSHELLS90450.0060.1584No
85TMEM79TMEM7991670.0050.1538No
86C4orf47C4orf4794570.0040.1412No
87NUSAP1NUSAP195060.0040.1397No
88E2F1E2F195340.0040.1392No
89NCAPHNCAPH95800.0040.1378No
90GCLMGCLM97160.0030.1321No
91CHAF1BCHAF1B97400.0030.1317No
92CACYBPCACYBP97420.0030.1322No
93TRIM36TRIM3699580.0020.1227No
94CHAF1ACHAF1A101320.0020.1150No
95SGOL2SGOL2102590.0010.1093No
96ABCA5ABCA5104210.0010.1020No
97EMP2EMP2105010.0010.0984No
98SPIN4SPIN4106480.0000.0916No
99SIP1SIP1106490.0000.0916No
100TYMSTYMS10714-0.0000.0886No
101PIN4PIN410730-0.0000.0880No
102LSM5LSM510878-0.0010.0812No
103HMMRHMMR10925-0.0010.0792No
104KIAA0895KIAA089511192-0.0020.0672No
105NCAPGNCAPG11200-0.0020.0672No
106EVC2EVC211477-0.0030.0549No
107KIF14KIF1412031-0.0050.0299No
108C17orf75C17orf7512035-0.0050.0307No
109E2F8E2F812050-0.0050.0310No
110RBM24RBM2412064-0.0050.0313No
111FANCD2FANCD212160-0.0050.0278No
112ZC3HAV1LZC3HAV1L12206-0.0050.0268No
113CDC2CDC212363-0.0060.0206No
114SHOX2SHOX212923-0.008-0.0040No
115ANKRD5ANKRD513001-0.008-0.0060No
116EFCAB2EFCAB213174-0.009-0.0123No
117PDK1PDK113252-0.009-0.0142No
118GMPSGMPS13258-0.009-0.0126No
119DLGAP5DLGAP513290-0.009-0.0123No
120FBXO11FBXO1113432-0.010-0.0170No
121TMEM38BTMEM38B13445-0.010-0.0157No
122PAWRPAWR13492-0.010-0.0159No
123EXOSC9EXOSC913539-0.010-0.0161No
124MAGOHMAGOH13631-0.011-0.0183No
125NUF2NUF213660-0.011-0.0176No
126BRCA1BRCA113703-0.011-0.0175No
127TIMELESSTIMELESS13865-0.011-0.0228No
128ERCC6LERCC6L14047-0.012-0.0289No
129C1orf133C1orf13314269-0.013-0.0367No
130CKS2CKS214596-0.014-0.0492No
131DTLDTL14609-0.014-0.0470No
132HAUS6HAUS614851-0.015-0.0554No
133ZWINTZWINT15079-0.016-0.0628No
134PRIM2PRIM215174-0.017-0.0640No
135HJURPHJURP15377-0.018-0.0701No
136CDKN2ACDKN2A15787-0.019-0.0854No
137MTF2MTF215829-0.020-0.0836No
138C3orf15C3orf1515876-0.020-0.0819No
139MCM6MCM616039-0.021-0.0856No
140ECT2ECT216101-0.021-0.0844No
141PPICPPIC16165-0.021-0.0833No
142ZNF367ZNF36716445-0.022-0.0921No
143CENPNCENPN16498-0.023-0.0901No
144SPC24SPC2416709-0.024-0.0954No
145AURKAAURKA17242-0.027-0.1152No
146WDR34WDR3417253-0.027-0.1105No
147DEKDEK17294-0.027-0.1073No
148CENPFCENPF17620-0.029-0.1170No
149RECQLRECQL18052-0.031-0.1311No
150TMPOTMPO18652-0.036-0.1523No
151IL13RA2IL13RA218711-0.036-0.1481No
152RAD51RAD5118816-0.037-0.1459No
153BUB1BUB118913-0.038-0.1432No
154E2F7E2F718955-0.038-0.1378No
155C6orf173C6orf17318998-0.039-0.1324No
156CENPECENPE19121-0.040-0.1304No
157TIFATIFA19209-0.041-0.1268No
158IFT74IFT7419364-0.042-0.1259No
159CCNB1CCNB119401-0.042-0.1195No
160ASPMASPM19569-0.044-0.1189No
161CCNE2CCNE219671-0.046-0.1149No
162NDC80NDC8019700-0.046-0.1075No
163STILSTIL19782-0.047-0.1023No
164KIF18AKIF18A19894-0.048-0.0982No
165CCDC138CCDC13819994-0.050-0.0933No
166C1orf112C1orf11220051-0.051-0.0863No
167C12orf48C12orf4820069-0.051-0.0774No
168TMEM106CTMEM106C20103-0.051-0.0691No
169NEK2NEK220480-0.058-0.0757No
170NUCB2NUCB220509-0.058-0.0658No
171C1orf97C1orf9720638-0.062-0.0601No
172ARNTL2ARNTL220855-0.068-0.0572No
173ACYP1ACYP121062-0.075-0.0525No
174WDHD1WDHD121236-0.086-0.0441No
175PRPS2PRPS221310-0.092-0.0301No
176ITGB3BPITGB3BP21405-0.105-0.0144No
177EIF1AXEIF1AX21479-0.1220.0054No
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_PROLIFERATIVE_2006   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_PROLIFERATIVE_2006: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_PROLIFERATIVE_2006