DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetPHILLIPS_PN_2006
Enrichment Score (ES)0.28624728
Normalized Enrichment Score (NES)1.3187621
Nominal p-value0.024948025
FDR q-value0.103173785
FWER p-Value0.592
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_PN_2006   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NTRK2NTRK2140.2250.0274Yes
2GRIA2GRIA2270.1780.0490Yes
3HEY2HEY2450.1550.0676Yes
4PCSK1NPCSK1N670.1420.0844Yes
5TPM1TPM11200.1160.0963Yes
6TMEM100TMEM1001390.1100.1093Yes
7RTN1RTN11410.1100.1229Yes
8SNRPNSNRPN1960.1000.1329Yes
9SEZ6LSEZ6L2280.0960.1434Yes
10WNT7BWNT7B2570.0930.1537Yes
11TIMP4TIMP43000.0900.1630Yes
12FBXO2FBXO23800.0830.1697Yes
13GPRC5BGPRC5B4120.0820.1785Yes
14SLIT1SLIT14170.0820.1885Yes
15SOX8SOX84460.0800.1972Yes
16THRATHRA4470.0800.2072Yes
17GRIA1GRIA14610.0800.2165Yes
18NCAM1NCAM15490.0750.2218Yes
19ATP6V1G2ATP6V1G25680.0740.2302Yes
20GAD1GAD16990.0690.2328Yes
21TMEM59LTMEM59L7040.0690.2413Yes
22IL17DIL17D7470.0680.2477Yes
23GAB2GAB28650.0640.2502Yes
24FXYD6FXYD68920.0630.2569Yes
25SLITRK5SLITRK512820.0550.2455Yes
26NUMA1NUMA112910.0550.2520Yes
27B3GAT1B3GAT113870.0530.2541Yes
28CRYABCRYAB14600.0520.2572Yes
29RASSF4RASSF414750.0520.2629Yes
30OLIG1OLIG115820.0500.2642Yes
31TTYH1TTYH116430.0490.2675Yes
32CCNKCCNK16570.0490.2731Yes
33FSD1FSD117020.0480.2770Yes
34ABLIM1ABLIM117550.0480.2805Yes
35NAP1L3NAP1L317730.0470.2857Yes
36PHYHIPLPHYHIPL18840.0460.2862Yes
37ZDHHC22ZDHHC2220640.0440.2834No
38GABBR2GABBR221680.0430.2839No
39SCG3SCG324870.0390.2739No
40RAC3RAC325730.0390.2748No
41LUZP2LUZP225960.0390.2785No
42PAR5PAR526090.0380.2828No
43KIF1AKIF1A29660.0360.2705No
44TMOD2TMOD229860.0350.2741No
45IKZF5IKZF530620.0350.2749No
46DPP10DPP1032430.0330.2707No
47C1QL1C1QL132680.0330.2737No
48FLRT1FLRT132820.0330.2772No
49PLCB1PLCB133120.0330.2799No
50DUSP26DUSP2634260.0320.2786No
51KCNQ5KCNQ535500.0310.2768No
52F2F236290.0310.2769No
53KCNN3KCNN337640.0300.2743No
54RIPPLY2RIPPLY237790.0300.2774No
55HSPA12AHSPA12A38050.0290.2799No
56EPB41L2EPB41L238980.0290.2791No
57CMTM5CMTM540510.0280.2755No
58WDR86WDR8640550.0280.2788No
59ZNF488ZNF48840560.0280.2823No
60GNAO1GNAO140750.0280.2849No
61C11orf2C11orf241290.0270.2859No
62psiTPTE22psiTPTE2242590.0270.2832No
63LRRC4LRRC442740.0270.2858No
64GRID1GRID144460.0260.2810No
65CALCRLCALCRL48910.0230.2631No
66SEC31BSEC31B50600.0220.2580No
67C13orf15C13orf1551740.0220.2554No
68BCANBCAN53830.0210.2483No
69JPH3JPH354110.0200.2496No
70RASL10ARASL10A54780.0200.2490No
71SCDSCD58070.0190.2360No
72FAM133AFAM133A60410.0180.2272No
73CDR1CDR160650.0170.2283No
74ADCY2ADCY261350.0170.2272No
75SGCGSGCG61920.0170.2267No
76MMP16MMP1662120.0170.2279No
77FUT9FUT962980.0160.2260No
78AKR1C1AKR1C165480.0150.2163No
79OMGOMG67130.0150.2104No
80NRSN1NRSN167540.0140.2104No
81CYFIP2CYFIP267760.0140.2112No
82SPHKAPSPHKAP68540.0140.2093No
83FAM19A5FAM19A571160.0130.1987No
84KSR2KSR271510.0130.1987No
85NALCNNALCN74020.0120.1885No
86PCSK6PCSK674480.0120.1879No
87FGF14FGF1475530.0110.1844No
88RAB11FIP4RAB11FIP480280.0090.1634No
89SLITRK2SLITRK280430.0090.1639No
90PLEKHB1PLEKHB184420.0080.1463No
91MPPE1MPPE184620.0080.1464No
92HLFHLF84770.0080.1467No
93ZC3H12BZC3H12B85050.0080.1464No
94P2RX7P2RX786060.0070.1427No
95ABLIM3ABLIM386940.0070.1395No
96SCN3ASCN3A87130.0070.1395No
97NET1NET187360.0070.1394No
98OVOL1OVOL187410.0070.1400No
99MARCH8MARCH887920.0070.1385No
100PHACTR3PHACTR388420.0060.1370No
101PDK2PDK290810.0060.1266No
102FAM155AFAM155A90870.0060.1271No
103SOX6SOX691370.0060.1255No
104RASGEF1CRASGEF1C93490.0050.1162No
105HIP1RHIP1R94970.0040.1098No
106REPS2REPS296070.0040.1052No
107FLJ16779FLJ1677996420.0040.1040No
108RPRMRPRM97370.0030.1000No
109KIF5AKIF5A97800.0030.0985No
110TRIM31TRIM3199150.0030.0925No
111ASCL1ASCL1102710.0010.0761No
112EPHB1EPHB1102730.0010.0762No
113SGSM1SGSM1104230.0010.0693No
114CSMD3CSMD3104410.0010.0686No
115P2RY13P2RY13105320.0000.0645No
116PDK4PDK4105480.0000.0638No
117NKAIN4NKAIN4105500.0000.0638No
118MN1MN1105630.0000.0633No
119BEND7BEND7106440.0000.0596No
120GNALGNAL10853-0.0010.0499No
121SORBS1SORBS110911-0.0010.0473No
122PKNOX2PKNOX211018-0.0010.0425No
123NTN4NTN411035-0.0010.0419No
124MAPTMAPT11069-0.0010.0405No
125KCNB1KCNB111153-0.0020.0369No
126FGF13FGF1311372-0.0020.0270No
127PRKCZPRKCZ11556-0.0030.0188No
128DOK6DOK611846-0.0040.0058No
129ARHGAP22ARHGAP2212000-0.005-0.0008No
130PSDPSD12036-0.005-0.0018No
131SORCS3SORCS312038-0.005-0.0013No
132FGF12FGF1212435-0.006-0.0190No
133GRIA4GRIA412459-0.006-0.0193No
134TMLHETMLHE12478-0.006-0.0194No
135DTX4DTX412548-0.007-0.0218No
136DLL1DLL112760-0.007-0.0307No
137SMAD9SMAD912940-0.008-0.0381No
138GABRA3GABRA312970-0.008-0.0385No
139KLRC3KLRC313100-0.009-0.0434No
140ASB13ASB1313194-0.009-0.0467No
141C12orf53C12orf5313561-0.010-0.0625No
142SNAP91SNAP9113591-0.010-0.0626No
143FERMT1FERMT113596-0.010-0.0615No
144AJAP1AJAP113934-0.012-0.0758No
145CRTC1CRTC114224-0.013-0.0877No
146PDE2APDE2A14236-0.013-0.0866No
147SHDSHD14332-0.013-0.0894No
148GABRB3GABRB314334-0.013-0.0877No
149ZCCHC24ZCCHC2414458-0.014-0.0918No
150DLL3DLL314605-0.014-0.0968No
151CNTN3CNTN314740-0.015-0.1012No
152GABBR1GABBR114827-0.015-0.1033No
153KCTD4KCTD414935-0.016-0.1064No
154ATRNL1ATRNL115040-0.016-0.1092No
155NDRG2NDRG215120-0.017-0.1109No
156DSCAML1DSCAML115376-0.018-0.1206No
157ID4ID415399-0.018-0.1194No
158RGS9RGS915474-0.018-0.1206No
159KIF21BKIF21B15568-0.018-0.1227No
160GPR158GPR15815705-0.019-0.1267No
161MCF2MCF215808-0.020-0.1290No
162RUNDC3ARUNDC3A16030-0.021-0.1368No
163NEU4NEU416227-0.022-0.1433No
164FBXL15FBXL1516286-0.022-0.1433No
165GLUD1GLUD116502-0.023-0.1505No
166STOX1STOX116589-0.023-0.1516No
167GFRA1GFRA116618-0.023-0.1500No
168TPCN2TPCN216788-0.024-0.1549No
169RIMS2RIMS217201-0.026-0.1709No
170TAL1TAL117243-0.027-0.1695No
171AP2B1AP2B117307-0.027-0.1691No
172RPL13RPL1317362-0.027-0.1682No
173ELMO1ELMO117786-0.030-0.1843No
174USH1CUSH1C17846-0.030-0.1834No
175CNTN1CNTN117931-0.031-0.1835No
176GLUD2GLUD217976-0.031-0.1817No
177JPH4JPH418046-0.031-0.1811No
178GGTA1GGTA118047-0.031-0.1772No
179NRG3NRG318101-0.032-0.1757No
180SLC25A21SLC25A2118124-0.032-0.1728No
181RPL37RPL3718247-0.033-0.1744No
182PID1PID118259-0.033-0.1709No
183TNKS2TNKS218264-0.033-0.1670No
184CBX7CBX718278-0.033-0.1635No
185FSTL5FSTL518308-0.033-0.1608No
186SMOC1SMOC118310-0.033-0.1567No
187SSTR2SSTR218316-0.033-0.1528No
188ACSM5ACSM518397-0.034-0.1524No
189MAPK8IP2MAPK8IP218423-0.034-0.1493No
190CSDC2CSDC218464-0.034-0.1469No
191FRYFRY18585-0.035-0.1481No
192BMP2BMP218843-0.037-0.1555No
193HDAC5HDAC518847-0.037-0.1510No
194SH3GL2SH3GL218995-0.039-0.1531No
195NOGNOG19054-0.039-0.1509No
196GRIK4GRIK419077-0.039-0.1470No
197DNM3DNM319167-0.040-0.1462No
198LGR5LGR519567-0.044-0.1593No
199EFHA2EFHA219707-0.046-0.1601No
200SLC1A1SLC1A119759-0.047-0.1567No
201ALDH5A1ALDH5A119835-0.048-0.1543No
202OLIG2OLIG219896-0.049-0.1510No
203CALN1CALN119946-0.049-0.1472No
204SSTR1SSTR119990-0.050-0.1430No
205PKP4PKP420046-0.051-0.1393No
206PARD3PARD320063-0.051-0.1337No
207ENHOENHO20124-0.052-0.1301No
208ANKS1BANKS1B20262-0.054-0.1297No
209MAFMAF20429-0.057-0.1304No
210EHD3EHD320493-0.058-0.1262No
211ZNF804AZNF804A20595-0.060-0.1234No
212FAIM2FAIM220666-0.062-0.1189No
213SUSD5SUSD520697-0.063-0.1124No
214ARL3ARL320721-0.064-0.1055No
215CECR6CECR620795-0.066-0.1006No
216FAM110BFAM110B20872-0.068-0.0957No
217ALDOCALDOC20972-0.072-0.0914No
218DSCAMDSCAM20996-0.073-0.0834No
219DNAJC12DNAJC1221017-0.073-0.0752No
220OPCMLOPCML21056-0.075-0.0676No
221PTGDSPTGDS21153-0.080-0.0622No
222HS3ST4HS3ST421265-0.088-0.0564No
223ABHD6ABHD621294-0.090-0.0465No
224SLC1A4SLC1A421329-0.095-0.0363No
225GALNT13GALNT1321474-0.119-0.0282No
226APOEAPOE21593-0.2720.0001No
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_PN_2006   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_PN_2006: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_PN_2006