Dataset | NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos |
Phenotype | NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos |
Upregulated in class | Ctrl |
GeneSet | PHILLIPS_MES_2006 |
Enrichment Score (ES) | -0.41462108 |
Normalized Enrichment Score (NES) | -1.7570016 |
Nominal p-value | 0.0 |
FDR q-value | 0.0040573115 |
FWER p-Value | 0.014 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | SLC16A3 | SLC16A3 | 31 | 0.173 | 0.0284 | No |
2 | COL4A2 | COL4A2 | 76 | 0.139 | 0.0502 | No |
3 | C1R | C1R | 108 | 0.120 | 0.0695 | No |
4 | SALL4 | SALL4 | 123 | 0.114 | 0.0885 | No |
5 | FAM20C | FAM20C | 128 | 0.112 | 0.1076 | No |
6 | SOCS3 | SOCS3 | 538 | 0.076 | 0.1016 | No |
7 | COL4A1 | COL4A1 | 732 | 0.068 | 0.1044 | No |
8 | RHOJ | RHOJ | 899 | 0.063 | 0.1074 | No |
9 | TWF1 | TWF1 | 911 | 0.062 | 0.1177 | No |
10 | FLNA | FLNA | 933 | 0.062 | 0.1274 | No |
11 | EFEMP2 | EFEMP2 | 1047 | 0.060 | 0.1324 | No |
12 | ANGPTL4 | ANGPTL4 | 1289 | 0.055 | 0.1306 | No |
13 | OSMR | OSMR | 1457 | 0.052 | 0.1317 | No |
14 | JUNB | JUNB | 1660 | 0.049 | 0.1307 | No |
15 | EPAS1 | EPAS1 | 1753 | 0.048 | 0.1346 | No |
16 | THBD | THBD | 1759 | 0.048 | 0.1426 | No |
17 | NRP2 | NRP2 | 1947 | 0.045 | 0.1417 | No |
18 | SHC1 | SHC1 | 2099 | 0.044 | 0.1421 | No |
19 | BCL3 | BCL3 | 2307 | 0.041 | 0.1395 | No |
20 | RYR3 | RYR3 | 2410 | 0.040 | 0.1417 | No |
21 | C15orf52 | C15orf52 | 2436 | 0.040 | 0.1473 | No |
22 | ANPEP | ANPEP | 2706 | 0.038 | 0.1413 | No |
23 | PDLIM7 | PDLIM7 | 3162 | 0.034 | 0.1259 | No |
24 | PDGFRL | PDGFRL | 3174 | 0.034 | 0.1312 | No |
25 | PARP10 | PARP10 | 3573 | 0.031 | 0.1180 | No |
26 | ACTA2 | ACTA2 | 3608 | 0.031 | 0.1217 | No |
27 | FES | FES | 3658 | 0.030 | 0.1247 | No |
28 | C1QTNF1 | C1QTNF1 | 3773 | 0.030 | 0.1245 | No |
29 | STEAP3 | STEAP3 | 3794 | 0.029 | 0.1286 | No |
30 | SLC12A9 | SLC12A9 | 3874 | 0.029 | 0.1299 | No |
31 | BACE2 | BACE2 | 3897 | 0.029 | 0.1338 | No |
32 | LPAR1 | LPAR1 | 3933 | 0.029 | 0.1371 | No |
33 | TPP1 | TPP1 | 4503 | 0.025 | 0.1150 | No |
34 | TRIM56 | TRIM56 | 4505 | 0.025 | 0.1193 | No |
35 | MYL9 | MYL9 | 4571 | 0.025 | 0.1205 | No |
36 | FPR2 | FPR2 | 4676 | 0.024 | 0.1198 | No |
37 | SGSH | SGSH | 4705 | 0.024 | 0.1226 | No |
38 | KLF16 | KLF16 | 4901 | 0.023 | 0.1175 | No |
39 | GGN | GGN | 5113 | 0.022 | 0.1114 | No |
40 | DEF6 | DEF6 | 5581 | 0.020 | 0.0931 | No |
41 | PVRL2 | PVRL2 | 5908 | 0.018 | 0.0810 | No |
42 | NRP1 | NRP1 | 6636 | 0.015 | 0.0497 | No |
43 | FLT1 | FLT1 | 6853 | 0.014 | 0.0421 | No |
44 | HK3 | HK3 | 7250 | 0.012 | 0.0258 | No |
45 | DLC1 | DLC1 | 8159 | 0.009 | -0.0149 | No |
46 | VWA1 | VWA1 | 8282 | 0.009 | -0.0192 | No |
47 | IL32 | IL32 | 8306 | 0.008 | -0.0188 | No |
48 | SHROOM3 | SHROOM3 | 8405 | 0.008 | -0.0219 | No |
49 | CD248 | CD248 | 8480 | 0.008 | -0.0240 | No |
50 | PDGFA | PDGFA | 9046 | 0.006 | -0.0494 | No |
51 | PLA2G5 | PLA2G5 | 9825 | 0.003 | -0.0851 | No |
52 | SLC39A8 | SLC39A8 | 10462 | 0.001 | -0.1146 | No |
53 | TAGLN | TAGLN | 10574 | 0.000 | -0.1197 | No |
54 | MAP2K3 | MAP2K3 | 10600 | 0.000 | -0.1209 | No |
55 | RRBP1 | RRBP1 | 10959 | -0.001 | -0.1374 | No |
56 | FOSL2 | FOSL2 | 11178 | -0.002 | -0.1472 | No |
57 | RUNX1 | RUNX1 | 11533 | -0.003 | -0.1632 | No |
58 | CA12 | CA12 | 12657 | -0.007 | -0.2143 | No |
59 | SERPINA1 | SERPINA1 | 12892 | -0.008 | -0.2238 | No |
60 | CD97 | CD97 | 12979 | -0.008 | -0.2264 | No |
61 | FCGR2C | FCGR2C | 13021 | -0.008 | -0.2269 | No |
62 | CECR2 | CECR2 | 13164 | -0.009 | -0.2320 | No |
63 | ACTN1 | ACTN1 | 13245 | -0.009 | -0.2341 | No |
64 | CD151 | CD151 | 13304 | -0.009 | -0.2352 | No |
65 | FAM38A | FAM38A | 13376 | -0.010 | -0.2369 | No |
66 | TRIM47 | TRIM47 | 13644 | -0.011 | -0.2475 | No |
67 | PI3 | PI3 | 13838 | -0.011 | -0.2545 | No |
68 | HRH1 | HRH1 | 14572 | -0.014 | -0.2862 | No |
69 | ANGPT2 | ANGPT2 | 14888 | -0.016 | -0.2982 | No |
70 | LRRC32 | LRRC32 | 15357 | -0.018 | -0.3170 | No |
71 | TRABD | TRABD | 15409 | -0.018 | -0.3163 | No |
72 | NCLN | NCLN | 15460 | -0.018 | -0.3155 | No |
73 | ECE1 | ECE1 | 15587 | -0.019 | -0.3182 | No |
74 | MYH9 | MYH9 | 15863 | -0.020 | -0.3276 | No |
75 | RAB34 | RAB34 | 15885 | -0.020 | -0.3251 | No |
76 | GPR116 | GPR116 | 16131 | -0.021 | -0.3329 | No |
77 | PDPN | PDPN | 16322 | -0.022 | -0.3380 | No |
78 | ITGA7 | ITGA7 | 16442 | -0.022 | -0.3397 | No |
79 | TNC | TNC | 16569 | -0.023 | -0.3416 | No |
80 | PMEPA1 | PMEPA1 | 17051 | -0.026 | -0.3596 | No |
81 | ESM1 | ESM1 | 17075 | -0.026 | -0.3563 | No |
82 | ICAM1 | ICAM1 | 17117 | -0.026 | -0.3537 | No |
83 | LRRC29 | LRRC29 | 17347 | -0.027 | -0.3597 | No |
84 | C22orf26 | C22orf26 | 17724 | -0.029 | -0.3722 | No |
85 | SBNO2 | SBNO2 | 17893 | -0.030 | -0.3748 | No |
86 | MVP | MVP | 18318 | -0.033 | -0.3888 | No |
87 | IFITM2 | IFITM2 | 18618 | -0.035 | -0.3967 | No |
88 | FGG | FGG | 18706 | -0.036 | -0.3945 | No |
89 | TNFRSF10D | TNFRSF10D | 18900 | -0.038 | -0.3970 | No |
90 | HOMER3 | HOMER3 | 19026 | -0.039 | -0.3961 | No |
91 | IFITM3 | IFITM3 | 19155 | -0.040 | -0.3952 | No |
92 | NEURL2 | NEURL2 | 19573 | -0.044 | -0.4070 | Yes |
93 | PLAUR | PLAUR | 19606 | -0.045 | -0.4008 | Yes |
94 | C1RL | C1RL | 19665 | -0.046 | -0.3956 | Yes |
95 | UNC93B1 | UNC93B1 | 19712 | -0.046 | -0.3899 | Yes |
96 | TTC38 | TTC38 | 19716 | -0.046 | -0.3821 | Yes |
97 | EMP3 | EMP3 | 19792 | -0.047 | -0.3775 | Yes |
98 | ITGA5 | ITGA5 | 20099 | -0.051 | -0.3829 | Yes |
99 | HSD3B7 | HSD3B7 | 20165 | -0.052 | -0.3770 | Yes |
100 | LZTS1 | LZTS1 | 20169 | -0.052 | -0.3682 | Yes |
101 | PTRF | PTRF | 20222 | -0.053 | -0.3614 | Yes |
102 | OSBPL3 | OSBPL3 | 20251 | -0.054 | -0.3535 | Yes |
103 | FBN1 | FBN1 | 20442 | -0.057 | -0.3525 | Yes |
104 | ZYX | ZYX | 20520 | -0.059 | -0.3461 | Yes |
105 | PLEKHF1 | PLEKHF1 | 20606 | -0.061 | -0.3396 | Yes |
106 | RRAS | RRAS | 20702 | -0.064 | -0.3331 | Yes |
107 | SLC25A37 | SLC25A37 | 20764 | -0.065 | -0.3247 | Yes |
108 | FGFRL1 | FGFRL1 | 20784 | -0.066 | -0.3143 | Yes |
109 | SERPINH1 | SERPINH1 | 20869 | -0.068 | -0.3065 | Yes |
110 | MMP14 | MMP14 | 20926 | -0.070 | -0.2970 | Yes |
111 | EHD2 | EHD2 | 20980 | -0.072 | -0.2871 | Yes |
112 | TIMP1 | TIMP1 | 21029 | -0.074 | -0.2766 | Yes |
113 | S100A11 | S100A11 | 21047 | -0.075 | -0.2646 | Yes |
114 | EFNB2 | EFNB2 | 21255 | -0.087 | -0.2592 | Yes |
115 | PAPPA | PAPPA | 21297 | -0.090 | -0.2456 | Yes |
116 | PDLIM4 | PDLIM4 | 21316 | -0.092 | -0.2305 | Yes |
117 | SLC22A18 | SLC22A18 | 21336 | -0.096 | -0.2150 | Yes |
118 | LIF | LIF | 21404 | -0.105 | -0.2000 | Yes |
119 | SPOCD1 | SPOCD1 | 21473 | -0.118 | -0.1828 | Yes |
120 | PLAU | PLAU | 21507 | -0.141 | -0.1601 | Yes |
121 | EMP1 | EMP1 | 21515 | -0.145 | -0.1356 | Yes |
122 | SERPINE1 | SERPINE1 | 21554 | -0.173 | -0.1075 | Yes |
123 | CHI3L1 | CHI3L1 | 21572 | -0.194 | -0.0750 | Yes |
124 | ITGA3 | ITGA3 | 21577 | -0.205 | -0.0399 | Yes |
125 | METTL7B | METTL7B | 21587 | -0.236 | 0.0004 | Yes |