Dataset | NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos |
Phenotype | NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos |
Upregulated in class | GRD |
GeneSet | NEFTEL_MES2_2019 |
Enrichment Score (ES) | 0.473447 |
Normalized Enrichment Score (NES) | 1.6622528 |
Nominal p-value | 0.004149378 |
FDR q-value | 0.008401492 |
FWER p-Value | 0.043 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | ANXA2 | ANXA2 | 41 | 0.164 | 0.0461 | Yes |
2 | BNIP3L | BNIP3L | 60 | 0.144 | 0.0876 | Yes |
3 | ERO1L | ERO1L | 70 | 0.140 | 0.1285 | Yes |
4 | P4HA1 | P4HA1 | 80 | 0.135 | 0.1677 | Yes |
5 | SLC6A6 | SLC6A6 | 113 | 0.117 | 0.2006 | Yes |
6 | INSIG2 | INSIG2 | 152 | 0.107 | 0.2304 | Yes |
7 | PLOD2 | PLOD2 | 157 | 0.107 | 0.2616 | Yes |
8 | CA9 | CA9 | 191 | 0.101 | 0.2898 | Yes |
9 | ENO2 | ENO2 | 222 | 0.097 | 0.3168 | Yes |
10 | NAMPT | NAMPT | 433 | 0.081 | 0.3308 | Yes |
11 | PPP1R15A | PPP1R15A | 477 | 0.079 | 0.3519 | Yes |
12 | ADM | ADM | 533 | 0.076 | 0.3718 | Yes |
13 | SLC2A1 | SLC2A1 | 541 | 0.076 | 0.3937 | Yes |
14 | BNIP3 | BNIP3 | 620 | 0.072 | 0.4112 | Yes |
15 | PGK1 | PGK1 | 897 | 0.063 | 0.4169 | Yes |
16 | SLC2A3 | SLC2A3 | 977 | 0.061 | 0.4312 | Yes |
17 | ANGPTL4 | ANGPTL4 | 1289 | 0.055 | 0.4328 | Yes |
18 | VIM | VIM | 1546 | 0.051 | 0.4358 | Yes |
19 | AKAP12 | AKAP12 | 1567 | 0.050 | 0.4496 | Yes |
20 | UFM1 | UFM1 | 1675 | 0.049 | 0.4590 | Yes |
21 | EPAS1 | EPAS1 | 1753 | 0.048 | 0.4694 | Yes |
22 | DNAJB9 | DNAJB9 | 1954 | 0.045 | 0.4734 | Yes |
23 | LGALS3 | LGALS3 | 2318 | 0.041 | 0.4686 | No |
24 | EGLN3 | EGLN3 | 2526 | 0.039 | 0.4705 | No |
25 | GBE1 | GBE1 | 2760 | 0.037 | 0.4706 | No |
26 | PFKP | PFKP | 3701 | 0.030 | 0.4359 | No |
27 | XPOT | XPOT | 4630 | 0.024 | 0.4000 | No |
28 | LDHA | LDHA | 5202 | 0.022 | 0.3798 | No |
29 | NRN1 | NRN1 | 6540 | 0.015 | 0.3223 | No |
30 | HSPA5 | HSPA5 | 9422 | 0.004 | 0.1899 | No |
31 | FTL | FTL | 9543 | 0.004 | 0.1855 | No |
32 | SLC39A14 | SLC39A14 | 10792 | -0.000 | 0.1277 | No |
33 | ATF3 | ATF3 | 11356 | -0.002 | 0.1023 | No |
34 | GOLT1B | GOLT1B | 11639 | -0.003 | 0.0902 | No |
35 | TRAM1 | TRAM1 | 13353 | -0.010 | 0.0135 | No |
36 | HERPUD1 | HERPUD1 | 14200 | -0.013 | -0.0220 | No |
37 | HSPA9 | HSPA9 | 16238 | -0.022 | -0.1102 | No |
38 | RPL21 | RPL21 | 17015 | -0.025 | -0.1388 | No |
39 | IGFBP3 | IGFBP3 | 19998 | -0.050 | -0.2625 | No |
40 | SQSTM1 | SQSTM1 | 20653 | -0.062 | -0.2747 | No |
41 | DDIT3 | DDIT3 | 20728 | -0.064 | -0.2593 | No |
42 | ASNS | ASNS | 20893 | -0.069 | -0.2465 | No |
43 | CDKN1A | CDKN1A | 20989 | -0.072 | -0.2297 | No |
44 | SERTAD1 | SERTAD1 | 21172 | -0.081 | -0.2142 | No |
45 | MT1X | MT1X | 21257 | -0.087 | -0.1925 | No |
46 | WARS | WARS | 21449 | -0.112 | -0.1684 | No |
47 | NDRG1 | NDRG1 | 21524 | -0.149 | -0.1280 | No |
48 | TRIB3 | TRIB3 | 21564 | -0.183 | -0.0760 | No |
49 | GDF15 | GDF15 | 21592 | -0.263 | 0.0001 | No |