DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetFOSL1_REGULON
Enrichment Score (ES)-0.57744354
Normalized Enrichment Score (NES)-2.627471
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: FOSL1_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ANXA2ANXA2410.1640.0131No
2ANXA1ANXA1870.1330.0233No
3CTNND2CTNND21420.1090.0308No
4MAP2MAP21450.1080.0407No
5CD44CD442810.0920.0428No
6UPP1UPP16940.0700.0300No
7ANXA2P3ANXA2P37150.0690.0354No
8PARVAPARVA7440.0680.0403No
9VCLVCL8220.0650.0427No
10FLNAFLNA9330.0620.0433No
11CDKN1BCDKN1B10880.0590.0415No
12TRAM2TRAM212180.0560.0406No
13MARCKSL1MARCKSL115000.0510.0322No
14ANXA2P2ANXA2P216300.0490.0307No
15PQLC3PQLC316420.0490.0347No
16IMPAD1IMPAD117770.0470.0328No
17ZMYM4ZMYM418750.0460.0325No
18ZBTB38ZBTB3820560.0440.0281No
19SHC1SHC120990.0440.0302No
20CD46CD4621850.0430.0301No
21DEGS1DEGS122550.0420.0307No
22MAST1MAST125780.0390.0193No
23ANPEPANPEP27060.0380.0168No
24GBE1GBE127600.0370.0177No
25STC1STC133030.033-0.0046No
26PLCB1PLCB133120.033-0.0019No
27BET1LBET1L34960.032-0.0076No
28S100A10S100A1037820.030-0.0182No
29TPM2TPM238170.029-0.0171No
30MAFGMAFG38360.029-0.0153No
31AKR1C3AKR1C338440.029-0.0129No
32ABCD1ABCD138580.029-0.0108No
33MYD88MYD8838920.029-0.0097No
34BACE2BACE238970.029-0.0073No
35EXOC3EXOC340480.028-0.0117No
36TCF4TCF445300.025-0.0319No
37IL13RA1IL13RA146250.025-0.0340No
38CLIP4CLIP451090.022-0.0546No
39CRIM1CRIM152060.022-0.0571No
40WDR1WDR157400.019-0.0803No
41CHD7CHD760150.018-0.0915No
42ADRM1ADRM160430.018-0.0912No
43MAN1A1MAN1A161910.017-0.0965No
44FUT9FUT962980.016-0.0999No
45B3GNT2B3GNT263650.016-0.1015No
46CAV2CAV267110.015-0.1163No
47SMAGPSMAGP68810.014-0.1229No
48AXLAXL75430.011-0.1528No
49LRRFIP2LRRFIP277090.011-0.1595No
50DSTNDSTN79170.010-0.1683No
51BFSP1BFSP181900.009-0.1802No
52SLC38A10SLC38A1082460.009-0.1820No
53GLIPR1GLIPR182580.009-0.1817No
54TPD52L2TPD52L284030.008-0.1877No
55GLT8D2GLT8D286170.007-0.1970No
56BAG3BAG391420.005-0.2210No
57MCFD2MCFD293940.005-0.2323No
58HSPA5HSPA594220.004-0.2332No
59RAC2RAC294550.004-0.2343No
60CYB561CYB56195890.004-0.2401No
61ANXA11ANXA1196000.004-0.2403No
62RHOGRHOG98340.003-0.2509No
63TMEM109TMEM109100130.002-0.2590No
64SEMA4FSEMA4F102810.001-0.2714No
65PMAIP1PMAIP1103280.001-0.2734No
66KCNN4KCNN4103340.001-0.2736No
67ARFRP1ARFRP1103530.001-0.2743No
68COL6A2COL6A2104170.001-0.2772No
69LGALS8LGALS8104380.001-0.2780No
70SERINC3SERINC310713-0.000-0.2908No
71PRNPPRNP10742-0.000-0.2921No
72KCND2KCND210763-0.000-0.2930No
73MGAT4BMGAT4B10778-0.000-0.2937No
74TNFRSF10BTNFRSF10B10856-0.001-0.2972No
75RRBP1RRBP110959-0.001-0.3019No
76OLFML2BOLFML2B11166-0.002-0.3114No
77ESYT1ESYT111172-0.002-0.3114No
78FOSL2FOSL211178-0.002-0.3115No
79APOBEC3BAPOBEC3B11389-0.003-0.3211No
80MYOFMYOF11422-0.003-0.3223No
81S100A13S100A1312345-0.006-0.3649No
82LGALS1LGALS112490-0.006-0.3711No
83CXXC4CXXC412495-0.006-0.3707No
84FOXC1FOXC113007-0.008-0.3938No
85METMET13160-0.009-0.4001No
86ACTN1ACTN113245-0.009-0.4032No
87RAVER2RAVER213442-0.010-0.4115No
88FLIIFLII13589-0.010-0.4173No
89ITGA6ITGA613656-0.011-0.4194No
90RELBRELB14022-0.012-0.4354No
91LPPLPP14112-0.013-0.4384No
92FBRSFBRS14331-0.013-0.4474No
93KLHL21KLHL2114354-0.013-0.4472No
94CAV1CAV114427-0.014-0.4493No
95ANXA4ANXA414597-0.014-0.4559No
96RNH1RNH114608-0.014-0.4550No
97ANP32AANP32A14657-0.015-0.4559No
98IL18R1IL18R114781-0.015-0.4603No
99TXNTXN15009-0.016-0.4694No
100FADS3FADS315104-0.017-0.4723No
101ACTN4ACTN415234-0.017-0.4767No
102RPS6KA4RPS6KA415237-0.017-0.4753No
103ARSAARSA15481-0.018-0.4850No
104VDRVDR15499-0.018-0.4841No
105PIGTPIGT15640-0.019-0.4889No
106PTGER4PTGER415657-0.019-0.4879No
107GEMGEM15692-0.019-0.4878No
108FOXN3FOXN315699-0.019-0.4863No
109MYH9MYH915863-0.020-0.4921No
110FHL2FHL215905-0.020-0.4922No
111KCND1KCND116049-0.021-0.4970No
112VASPVASP16317-0.022-0.5074No
113SRPX2SRPX216721-0.024-0.5241No
114IFRD2IFRD216761-0.024-0.5237No
115GSTA4GSTA417184-0.026-0.5410No
116EDEM1EDEM117197-0.026-0.5391No
117REXO2REXO217287-0.027-0.5408No
118TAPBPTAPBP17481-0.028-0.5473No
119PERPPERP17526-0.028-0.5467No
120MGAT1MGAT117652-0.029-0.5499No
121TMED9TMED918120-0.032-0.5689No
122SERPINB6SERPINB618196-0.032-0.5694No
123CBX7CBX718278-0.033-0.5702No
124MVPMVP18318-0.033-0.5689No
125YIPF3YIPF318348-0.033-0.5672No
126MYLKMYLK18526-0.035-0.5723No
127DNAJC10DNAJC1018556-0.035-0.5705No
128CSRP1CSRP118681-0.036-0.5730No
129GFPT2GFPT218731-0.036-0.5719No
130SSH3SSH318771-0.037-0.5704No
131SH3BGRL3SH3BGRL318804-0.037-0.5685No
132TSPAN7TSPAN718945-0.038-0.5715No
133KCNAB2KCNAB218977-0.038-0.5694No
134LMNALMNA19085-0.039-0.5708No
135ATP1A1ATP1A119146-0.040-0.5699No
136KDELR3KDELR319172-0.040-0.5674No
137GSDMDGSDMD19363-0.042-0.5724No
138P4HA2P4HA219472-0.043-0.5735Yes
139WDR55WDR5519475-0.043-0.5696Yes
140CRTAMCRTAM19489-0.043-0.5662Yes
141CAPN2CAPN219513-0.044-0.5632Yes
142CASTCAST19519-0.044-0.5595Yes
143PLAURPLAUR19606-0.045-0.5594Yes
144FADDFADD19627-0.045-0.5561Yes
145CDC42EP3CDC42EP319644-0.045-0.5527Yes
146SLC10A3SLC10A319691-0.046-0.5507Yes
147EMP3EMP319792-0.047-0.5510Yes
148TMEM214TMEM21419809-0.047-0.5474Yes
149QSOX1QSOX119823-0.047-0.5437Yes
150PARP12PARP1219840-0.048-0.5400Yes
151MOCOSMOCOS19883-0.048-0.5375Yes
152PXNPXN19986-0.050-0.5378Yes
153PARVBPARVB20036-0.050-0.5354Yes
154FYCO1FYCO120080-0.051-0.5327Yes
155DLX2DLX220090-0.051-0.5284Yes
156ITGA5ITGA520099-0.051-0.5241Yes
157CLIC1CLIC120260-0.054-0.5266Yes
158ETHE1ETHE120382-0.056-0.5271Yes
159ADSSADSS20415-0.057-0.5234Yes
160CUL7CUL720458-0.057-0.5201Yes
161CYBRD1CYBRD120489-0.058-0.5162Yes
162NSMAFNSMAF20593-0.060-0.5155Yes
163PLEKHF1PLEKHF120606-0.061-0.5104Yes
164TFPI2TFPI220632-0.062-0.5059Yes
165SQSTM1SQSTM120653-0.062-0.5012Yes
166MT2AMT2A20689-0.063-0.4970Yes
167RBKSRBKS20720-0.064-0.4925Yes
168COQ10BCOQ10B20781-0.066-0.4893Yes
169MYO1CMYO1C20807-0.066-0.4843Yes
170RNFT2RNFT220811-0.067-0.4783Yes
171GLRXGLRX20844-0.068-0.4736Yes
172S100A6S100A620850-0.068-0.4676Yes
173SH2D4ASH2D4A20863-0.068-0.4619Yes
174AHNAKAHNAK20906-0.070-0.4574Yes
175PNPLA2PNPLA220942-0.071-0.4526Yes
176RIN1RIN120944-0.071-0.4461Yes
177YIF1AYIF1A20945-0.071-0.4396Yes
178SLC35C1SLC35C120992-0.072-0.4350Yes
179ADORA2BADORA2B20998-0.073-0.4286Yes
180TIMP1TIMP121029-0.074-0.4232Yes
181S100A11S100A1121047-0.075-0.4171Yes
182DRAP1DRAP121080-0.076-0.4116Yes
183IQGAP1IQGAP121134-0.079-0.4068Yes
184TSPAN1TSPAN121147-0.080-0.4000Yes
185PHLDA2PHLDA221151-0.080-0.3928Yes
186ARPC1BARPC1B21177-0.082-0.3865Yes
187PLP2PLP221203-0.083-0.3800Yes
188DRAM1DRAM121232-0.086-0.3734Yes
189CEBPBCEBPB21289-0.090-0.3677Yes
190MICAL2MICAL221308-0.091-0.3601Yes
191FURINFURIN21311-0.092-0.3518Yes
192EPHA2EPHA221313-0.092-0.3434Yes
193SH2B3SH2B321319-0.093-0.3351Yes
194PROCRPROCR21321-0.093-0.3265Yes
195SYNJ2SYNJ221354-0.098-0.3190Yes
196DCBLD2DCBLD221387-0.103-0.3111Yes
197LIFLIF21404-0.105-0.3021Yes
198WIPI1WIPI121433-0.109-0.2934Yes
199NT5ENT5E21448-0.112-0.2838Yes
200G6PDG6PD21456-0.114-0.2736Yes
201PRSS23PRSS2321462-0.116-0.2631Yes
202IER3IER321480-0.122-0.2527Yes
203COL18A1COL18A121486-0.124-0.2415Yes
204SDC4SDC421489-0.125-0.2302Yes
205ATOX1ATOX121492-0.129-0.2184Yes
206FAHFAH21496-0.130-0.2066Yes
207PLAUPLAU21507-0.141-0.1941Yes
208RHBDF2RHBDF221513-0.144-0.1810Yes
209EMP1EMP121515-0.145-0.1678Yes
210AHNAK2AHNAK221523-0.148-0.1545Yes
211TNFRSF12ATNFRSF12A21534-0.154-0.1407Yes
212SERPINE1SERPINE121554-0.173-0.1257Yes
213PYGBPYGB21557-0.175-0.1096Yes
214PTHLHPTHLH21558-0.176-0.0934Yes
215MT1GMT1G21561-0.180-0.0770Yes
216IL11IL1121567-0.185-0.0602Yes
217ITGA3ITGA321577-0.205-0.0417Yes
218SLC4A7SLC4A721578-0.212-0.0222Yes
219ECM1ECM121591-0.2490.0002Yes
Table: GSEA details [plain text format]



Fig 2: FOSL1_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FOSL1_REGULON: Random ES distribution   
Gene set null distribution of ES for FOSL1_REGULON