DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetELF4_REGULON
Enrichment Score (ES)-0.40185383
Normalized Enrichment Score (NES)-1.7274532
Nominal p-value0.0
FDR q-value0.004455574
FWER p-Value0.02
Table: GSEA Results Summary



Fig 1: Enrichment plot: ELF4_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ANXA2ANXA2410.1640.0330No
2MAP2MAP21450.1080.0514No
3FBXO2FBXO23800.0830.0583No
4C3orf52C3orf525150.0770.0685No
5SLC39A6SLC39A66180.0720.0792No
6TOM1L1TOM1L17780.0670.0861No
7CASP6CASP69270.0620.0925No
8JAM3JAM314390.0520.0798No
9TMOD3TMOD315660.0500.0847No
10IFT88IFT8817270.0480.0875No
11ZBTB38ZBTB3820560.0440.0816No
12SCML1SCML120820.0440.0898No
13CLEC2BCLEC2B21060.0430.0980No
14RUSC1RUSC122860.0410.0985No
15CASP7CASP723170.0410.1059No
16CRABP2CRABP228850.0360.0872No
17CCNA1CCNA130750.0350.0859No
18PRSS12PRSS1234510.0320.0752No
19FESFES36580.0300.0721No
20PLP1PLP136710.0300.0780No
21CRYBG3CRYBG337960.0290.0785No
22CD83CD8343190.0260.0598No
23EFNA5EFNA543920.0260.0620No
24ZNF573ZNF57349370.0230.0416No
25POU3F2POU3F250210.0220.0425No
26PJA2PJA251930.0220.0391No
27OPTNOPTN52050.0220.0432No
28MDKMDK53100.0210.0428No
29BCANBCAN53830.0210.0439No
30ITPR3ITPR358080.0190.0281No
31GALNT6GALNT658290.0190.0311No
32FAM114A1FAM114A160370.0180.0253No
33PIK3C2BPIK3C2B61420.0170.0241No
34MAN1A1MAN1A161910.0170.0254No
35PPP1R13LPPP1R13L63590.0160.0211No
36MAFFMAFF63670.0160.0243No
37THYN1THYN164380.0160.0244No
38FZD6FZD665020.0160.0248No
39AP1G2AP1G265750.0150.0247No
40SMAGPSMAGP68810.0140.0134No
41ACOT9ACOT969210.0140.0146No
42LYNLYN71320.0130.0075No
43PRXPRX73770.012-0.0013No
44SERPINB1SERPINB173840.0120.0010No
45SLC25A24SLC25A2475650.011-0.0050No
46MICBMICB76880.011-0.0083No
47IL1R1IL1R178330.010-0.0128No
48IL15IL1580400.009-0.0204No
49RIBC2RIBC284900.008-0.0396No
50TCIRG1TCIRG186780.007-0.0468No
51BCAR3BCAR388620.006-0.0540No
52SFNSFN89090.006-0.0548No
53PLEKHA1PLEKHA189710.006-0.0563No
54C9orf40C9orf4090970.006-0.0610No
55ADCK2ADCK292690.005-0.0679No
56SLC46A3SLC46A395400.004-0.0796No
57ANXA11ANXA1196000.004-0.0815No
58NRTNNRTN99700.002-0.0982No
59HPCAL1HPCAL1100030.002-0.0992No
60SFT2D2SFT2D2101530.002-0.1057No
61ASCL1ASCL1102710.001-0.1109No
62CDS1CDS1105850.000-0.1254No
63HRASLSHRASLS106260.000-0.1273No
64EDNRBEDNRB10682-0.000-0.1298No
65OPA1OPA111026-0.001-0.1455No
66HYIHYI11130-0.002-0.1500No
67EHBP1L1EHBP1L111206-0.002-0.1531No
68HPSEHPSE11998-0.005-0.1890No
69TNFAIP2TNFAIP212244-0.006-0.1992No
70WDR44WDR4412287-0.006-0.1999No
71ALAS1ALAS112389-0.006-0.2034No
72RAB27ARAB27A12626-0.007-0.2129No
73HPS1HPS112772-0.007-0.2181No
74ROR2ROR213406-0.010-0.2455No
75TBC1D2BTBC1D2B13583-0.010-0.2515No
76FLIIFLII13589-0.010-0.2495No
77IL22RA1IL22RA113882-0.012-0.2606No
78PLEKHA5PLEKHA513974-0.012-0.2623No
79PCK2PCK213998-0.012-0.2608No
80DLG3DLG314496-0.014-0.2810No
81C6orf106C6orf10615039-0.016-0.3027No
82TUFT1TUFT115300-0.017-0.3112No
83SPAG4SPAG415315-0.017-0.3081No
84NIPAL2NIPAL215611-0.019-0.3179No
85INPP1INPP116488-0.023-0.3538No
86NUP62CLNUP62CL16780-0.024-0.3622No
87FLRT3FLRT316911-0.025-0.3630No
88ECHDC2ECHDC217288-0.027-0.3748No
89FBLN1FBLN117498-0.028-0.3785No
90PERPPERP17526-0.028-0.3737No
91DOCK5DOCK517588-0.029-0.3705No
92NCANNCAN17822-0.030-0.3750No
93OCRLOCRL18065-0.031-0.3796No
94SLC12A7SLC12A718422-0.034-0.3889No
95GCHFRGCHFR18701-0.036-0.3941Yes
96B3GALT4B3GALT418726-0.036-0.3875Yes
97PHF1PHF118754-0.036-0.3810Yes
98PRICKLE3PRICKLE318763-0.037-0.3735Yes
99SSH3SSH318771-0.037-0.3660Yes
100DNASE1L1DNASE1L118949-0.038-0.3661Yes
101CHAC1CHAC118979-0.038-0.3592Yes
102RASSF7RASSF719232-0.041-0.3622Yes
103TIAM1TIAM119371-0.042-0.3597Yes
104PLAURPLAUR19606-0.045-0.3610Yes
105SLC10A3SLC10A319691-0.046-0.3552Yes
106CDKN2DCDKN2D19768-0.047-0.3487Yes
107PARP12PARP1219840-0.048-0.3418Yes
108MOCOSMOCOS19883-0.048-0.3335Yes
109RUNX3RUNX320104-0.051-0.3327Yes
110HPRT1HPRT120301-0.055-0.3302Yes
111CYP1B1CYP1B120518-0.059-0.3277Yes
112EBPEBP20794-0.066-0.3264Yes
113MYO1CMYO1C20807-0.066-0.3128Yes
114GLRXGLRX20844-0.068-0.3000Yes
115ARNTL2ARNTL220855-0.068-0.2859Yes
116TRPC1TRPC120930-0.070-0.2744Yes
117SLC37A1SLC37A121013-0.073-0.2625Yes
118ABHD8ABHD821053-0.075-0.2484Yes
119UBL4AUBL4A21067-0.075-0.2328Yes
120IQGAP1IQGAP121134-0.079-0.2191Yes
121OPLAHOPLAH21138-0.079-0.2023Yes
122ARPC1BARPC1B21177-0.082-0.1866Yes
123PLP2PLP221203-0.083-0.1699Yes
124PPCSPPCS21215-0.084-0.1524Yes
125MICAL2MICAL221308-0.091-0.1371Yes
126PRPS2PRPS221310-0.092-0.1176Yes
127PROCRPROCR21321-0.093-0.0981Yes
128SIPA1SIPA121326-0.094-0.0782Yes
129BLVRBBLVRB21350-0.098-0.0584Yes
130HTATIP2HTATIP221373-0.101-0.0379Yes
131RPP25RPP2521422-0.107-0.0173Yes
132SLC9A3R1SLC9A3R121472-0.1180.0057Yes
Table: GSEA details [plain text format]



Fig 2: ELF4_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ELF4_REGULON: Random ES distribution   
Gene set null distribution of ES for ELF4_REGULON