DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetASCL1_REGULON
Enrichment Score (ES)0.47528905
Normalized Enrichment Score (NES)1.9207528
Nominal p-value0.0
FDR q-value7.443609E-4
FWER p-Value0.002
Table: GSEA Results Summary



Fig 1: Enrichment plot: ASCL1_REGULON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

SYMBOLTITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SCRG1SCRG110.3600.0762Yes
2PMP2PMP2150.2220.1225Yes
3PPP1R3CPPP1R3C220.1880.1621Yes
4GRIA2GRIA2270.1780.1997Yes
5CLASP2CLASP2340.1710.2357Yes
6NLGN4XNLGN4X810.1350.2622Yes
7MAP2MAP21450.1080.2822Yes
8TRIM9TRIM92100.0990.3002Yes
9SEMA5ASEMA5A3200.0890.3139Yes
10MTSS1MTSS13620.0850.3300Yes
11CDK6CDK64130.0820.3450Yes
12REV3LREV3L4710.0790.3591Yes
13KCNJ10KCNJ106840.0700.3641Yes
14GAD1GAD16990.0690.3782Yes
15ABATABAT8060.0660.3871Yes
16GAB2GAB28650.0640.3980Yes
17QKIQKI9540.0620.4070Yes
18TCF12TCF1211950.0570.4078Yes
19PTP4A3PTP4A312830.0550.4153Yes
20NLGN3NLGN313760.0530.4223Yes
21B3GAT1B3GAT113870.0530.4330Yes
22GPM6BGPM6B13980.0530.4437Yes
23JAKMIP2JAKMIP214090.0530.4544Yes
24RERERERE15010.0510.4610Yes
25TTYH1TTYH116430.0490.4648Yes
26ARHGEF9ARHGEF919050.0460.4624Yes
27RPE65RPE6519450.0450.4702Yes
28MTMR12MTMR1221180.0430.4714Yes
29RAB33ARAB33A22650.0420.4734Yes
30SCG3SCG324870.0390.4715Yes
31SNTG1SNTG127270.0380.4683Yes
32LPAR4LPAR429350.0360.4663Yes
33MYT1MYT130530.0350.4682Yes
34BMP7BMP730610.0350.4753Yes
35SMARCD3SMARCD333430.0330.4691No
36CSPG5CSPG541380.0270.4380No
37CRMP1CRMP149890.0230.4032No
38BBS7BBS751440.0220.4007No
39TUBB2BTUBB2B51450.0220.4053No
40BCANBCAN53830.0210.3986No
41PAK1PAK159330.0180.3769No
42ASTN1ASTN159980.0180.3777No
43CRB1CRB160170.0180.3806No
44SEPT2SEPT268430.0140.3452No
45PHLPP1PHLPP175980.0110.3125No
46SEPT7SEPT776040.0110.3146No
47SLC6A1SLC6A182860.0090.2847No
48PLXNB1PLXNB184650.0080.2781No
49MASP1MASP185930.0070.2738No
50P2RX7P2RX786060.0070.2748No
51HAPLN1HAPLN186440.0070.2746No
52BTG2BTG287890.0070.2694No
53PTNPTN89080.0060.2652No
54MLC1MLC194690.0040.2401No
55NTRK3NTRK397480.0030.2278No
56DOCK10DOCK10100050.0020.2164No
57KLF15KLF15105680.0000.1903No
58COBLCOBL10744-0.0000.1822No
59LSAMPLSAMP10946-0.0010.1731No
60MKNK1MKNK110976-0.0010.1719No
61WBP4WBP411761-0.0040.1363No
62SATB2SATB212011-0.0050.1257No
63ACSBG1ACSBG112021-0.0050.1263No
64C1orf61C1orf6112173-0.0050.1203No
65DCXDCX12388-0.0060.1117No
66RGRRGR12881-0.0080.0904No
67METMET13160-0.0090.0794No
68ZCCHC24ZCCHC2414458-0.0140.0220No
69NDRG2NDRG215120-0.017-0.0053No
70ID4ID415399-0.018-0.0144No
71OGFRL1OGFRL115664-0.019-0.0227No
72IL4RIL4R15794-0.020-0.0246No
73MAOBMAOB15939-0.020-0.0270No
74RHOQRHOQ15991-0.020-0.0250No
75SALL2SALL216354-0.022-0.0372No
76PCSK2PCSK217059-0.026-0.0645No
77CSGALNACT1CSGALNACT117475-0.028-0.0779No
78TPBGTPBG17767-0.029-0.0852No
79ELAVL4ELAVL417794-0.030-0.0802No
80NCANNCAN17822-0.030-0.0751No
81PID1PID118259-0.033-0.0885No
82ETV1ETV118514-0.035-0.0930No
83CADM4CADM418586-0.035-0.0888No
84MAP3K1MAP3K118630-0.035-0.0833No
85LMO1LMO118876-0.038-0.0867No
86GRIK4GRIK419077-0.039-0.0877No
87GPR37L1GPR37L119426-0.043-0.0948No
88BAG2BAG219537-0.044-0.0906No
89ELF4ELF419885-0.048-0.0966No
90OLIG2OLIG219896-0.049-0.0867No
91PTK7PTK720060-0.051-0.0836No
92TBC1D9TBC1D920519-0.059-0.0925No
93GANABGANAB20618-0.061-0.0841No
94UBN1UBN120969-0.072-0.0852No
95ATP2B2ATP2B221423-0.107-0.0836No
96IER3IER321480-0.122-0.0604No
97RHBDF2RHBDF221513-0.144-0.0313No
98PLS1PLS121541-0.1660.0025No
Table: GSEA details [plain text format]



Fig 2: ASCL1_REGULON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ASCL1_REGULON: Random ES distribution   
Gene set null distribution of ES for ASCL1_REGULON