DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetVERHAAK_PN_2010
Enrichment Score (ES)0.42768008
Normalized Enrichment Score (NES)1.9214442
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: VERHAAK_PN_2010   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GRIA2GRIA2270.1780.0333Yes
2CLASP2CLASP2340.1710.0661Yes
3MAP2MAP21450.1080.0820Yes
4SEZ6LSEZ6L2280.0960.0968Yes
5TMCC1TMCC12640.0930.1131Yes
6SRGAP3SRGAP33270.0880.1272Yes
7MTSS1MTSS13620.0850.1421Yes
8SNX26SNX263730.0840.1579Yes
9NCALDNCALD4030.0820.1724Yes
10NCAM1NCAM15490.0750.1803Yes
11ZNF286AZNF286A6680.0710.1884Yes
12ABATABAT8060.0660.1947Yes
13FXYD6FXYD68920.0630.2030Yes
14PPM1DPPM1D9950.0610.2100Yes
15CBX1CBX110000.0600.2215Yes
16RALGPS1RALGPS110500.0600.2307Yes
17CDKN1BCDKN1B10880.0590.2404Yes
18PLCB4PLCB411090.0580.2508Yes
19MYBMYB11660.0570.2593Yes
20FAM125BFAM125B11730.0570.2701Yes
21ZNF184ZNF18412170.0560.2789Yes
22STMN1STMN113300.0540.2841Yes
23SATB1SATB113480.0540.2937Yes
24DPYSL4DPYSL413680.0530.3031Yes
25NLGN3NLGN313760.0530.3130Yes
26TOP2BTOP2B14030.0530.3220Yes
27MARCKSL1MARCKSL115000.0510.3274Yes
28STMN4STMN415600.0500.3344Yes
29TTYH1TTYH116430.0490.3401Yes
30MATR3MATR316620.0490.3488Yes
31ATP1A3ATP1A316780.0490.3575Yes
32DBN1DBN118520.0460.3584Yes
33ARHGEF9ARHGEF919050.0460.3649Yes
34HN1HN119660.0450.3708Yes
35MARCKSMARCKS20320.0440.3763Yes
36TAF5TAF520710.0440.3831Yes
37SOX10SOX1022180.0420.3844Yes
38RAB33ARAB33A22650.0420.3903Yes
39NRXN2NRXN222720.0420.3981Yes
40BCORBCOR24260.0400.3987Yes
41SEC61A2SEC61A224690.0400.4044Yes
42SCG3SCG324870.0390.4112Yes
43MAST1MAST125780.0390.4145Yes
44KLRK1KLRK129430.0360.4044Yes
45MYT1MYT130530.0350.4061Yes
46C6orf134C6orf13431690.0340.4073Yes
47C1QL1C1QL132680.0330.4092Yes
48FLRT1FLRT132820.0330.4150Yes
49LPHN3LPHN333460.0330.4183Yes
50TMEFF1TMEFF133560.0330.4242Yes
51DUSP26DUSP2634260.0320.4272Yes
52ALCAMALCAM35480.0310.4276Yes
53WASF1WASF136730.0300.4277Yes
54CDK5R1CDK5R140540.0280.4153No
55CSPG5CSPG541380.0270.4168No
56TOPBP1TOPBP142660.0270.4160No
57BCL7ABCL7A42930.0260.4199No
58SLCO5A1SLCO5A145680.0250.4119No
59PFN2PFN246940.0240.4108No
60CRMP1CRMP149890.0230.4014No
61C1orf106C1orf10653330.0210.3894No
62BCANBCAN53830.0210.3911No
63VEZF1VEZF154510.0200.3919No
64ACTR1AACTR1A54700.0200.3950No
65PCDH11YPCDH11Y55990.0200.3928No
66PDE10APDE10A57440.0190.3898No
67SOX11SOX1157680.0190.3923No
68MMP15MMP1558620.0180.3915No
69RAP2ARAP2A59130.0180.3927No
70CHD7CHD760150.0180.3914No
71CRB1CRB160170.0180.3948No
72ZEB2ZEB261010.0170.3943No
73MMP16MMP1662120.0170.3924No
74DPF1DPF164160.0160.3860No
75CSNK1ECSNK1E64570.0160.3872No
76PAFAH1B3PAFAH1B366810.0150.3796No
77TSPAN3TSPAN369070.0140.3718No
78SOX2SOX269930.0130.3704No
79CASKCASK71340.0130.3664No
80YPEL1YPEL172940.0120.3614No
81GPR17GPR1773610.0120.3606No
82ZNF711ZNF71175920.0110.3520No
83PELI1PELI176140.0110.3532No
84GPM6AGPM6A77170.0110.3505No
85EPB41EPB4178920.0100.3444No
86AMOTL2AMOTL279000.0100.3460No
87AOF2AOF280050.0100.3430No
88MLLT11MLLT1180920.0090.3408No
89TTC3TTC381010.0090.3422No
90KLRC4KLRC482650.0090.3362No
91GNG4GNG483840.0080.3323No
92CDC7CDC785770.0080.3248No
93P2RX7P2RX786060.0070.3249No
94VAX2VAX286410.0070.3248No
95SCN3ASCN3A87130.0070.3228No
96MYST2MYST291830.0050.3020No
97PODXL2PODXL292260.0050.3010No
98LRP6LRP693120.0050.2980No
99GRID2GRID295390.0040.2882No
100GADD45GGADD45G97990.0030.2767No
101NOL4NOL498050.0030.2770No
102ASCL1ASCL1102710.0010.2556No
103EPHB1EPHB1102730.0010.2558No
104ZNF643ZNF643105180.0010.2445No
105HRASLSHRASLS106260.0000.2395No
106BAI3BAI310928-0.0010.2256No
107MAPTMAPT11069-0.0010.2194No
108ATAD5ATAD511274-0.0020.2102No
109HOXD3HOXD311340-0.0020.2077No
110FGF9FGF911403-0.0030.2053No
111ERBB3ERBB311564-0.0030.1984No
112RUFY3RUFY311730-0.0040.1915No
113IL1RAPL1IL1RAPL111783-0.0040.1898No
114SORCS3SORCS312038-0.0050.1788No
115DPP6DPP612045-0.0050.1795No
116TMEM35TMEM3512134-0.0050.1764No
117BEX1BEX112138-0.0050.1772No
118C1orf61C1orf6112173-0.0050.1767No
119DCXDCX12388-0.0060.1678No
120CXXC4CXXC412495-0.0060.1641No
121PHF16PHF1612818-0.0080.1506No
122GABRA3GABRA312970-0.0080.1451No
123RALGPS2RALGPS213046-0.0080.1432No
124PURGPURG13098-0.0090.1425No
125KLRC3KLRC313100-0.0090.1441No
126CLGNCLGN13156-0.0090.1433No
127PCDH11XPCDH11X13392-0.0100.1342No
128SOX4SOX413444-0.0100.1337No
129TOX3TOX313571-0.0100.1298No
130CA10CA1013883-0.0120.1176No
131ZNF510ZNF51014252-0.0130.1029No
132ZNF248ZNF24814416-0.0140.0979No
133HMGB3HMGB314419-0.0140.1005No
134RBPJRBPJ14462-0.0140.1012No
135RAD21RAD2114563-0.0140.0993No
136DLL3DLL314605-0.0140.1002No
137TMEM118TMEM11814809-0.0150.0936No
138CKBCKB15032-0.0160.0864No
139HDAC2HDAC215049-0.0160.0888No
140NR0B1NR0B115070-0.0160.0911No
141KIF21BKIF21B15568-0.0180.0714No
142NRXN1NRXN116554-0.0230.0299No
143PPM1EPPM1E16778-0.0240.0242No
144FHOD3FHOD317073-0.0260.0155No
145GSTA4GSTA417184-0.0260.0154No
146REEP1REEP117553-0.0280.0037No
147CAMSAP1L1CAMSAP1L117874-0.030-0.0054No
148CNTN1CNTN117931-0.031-0.0021No
149ICKICK18209-0.032-0.0087No
150PAK7PAK718244-0.033-0.0040No
151MYO10MYO1018482-0.034-0.0084No
152MCM10MCM1018493-0.035-0.0022No
153DGKIDGKI18589-0.0350.0002No
154SPTBN2SPTBN218605-0.0350.0063No
155FBXO21FBXO2118650-0.0360.0111No
156WDR68WDR6818813-0.0370.0107No
157PAK3PAK318892-0.0380.0144No
158DNM3DNM319167-0.0400.0094No
159E2F3E2F319227-0.0410.0146No
160MPPED2MPPED219357-0.0420.0167No
161SLC1A1SLC1A119759-0.0470.0070No
162OLIG2OLIG219896-0.0490.0100No
163CDC25ACDC25A19936-0.0490.0177No
164TNRC4TNRC420276-0.0540.0124No
165LRRTM4LRRTM420562-0.0600.0106No
166ZNF804AZNF804A20595-0.0600.0208No
167GSK3BGSK3B20757-0.0650.0258No
168FAM110BFAM110B20872-0.0680.0337No
Table: GSEA details [plain text format]



Fig 2: VERHAAK_PN_2010   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VERHAAK_PN_2010: Random ES distribution   
Gene set null distribution of ES for VERHAAK_PN_2010