Details for gene set VERHAAK_MES

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	Ctrl
GeneSet	VERHAAK_MES_2017
Enrichment Score (ES)	-0.3735108
Normalized Enrichment Score (NES)	-1.3257365
Nominal p-value	0.07878788
FDR q-value	0.055599563
FWER p-Value	0.251

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TGFBI	TGFBI	137	0.111	0.0555	No
2	ITGB1	ITGB1	677	0.070	0.0699	No
3	COL5A1	COL5A1	1392	0.053	0.0663	No
4	CNN2	CNN2	2016	0.045	0.0623	No
5	GPRC5A	GPRC5A	2052	0.044	0.0854	No
6	RGS2	RGS2	2154	0.043	0.1048	No
7	BCL3	BCL3	2307	0.041	0.1207	No
8	ANPEP	ANPEP	2706	0.038	0.1234	No
9	COL3A1	COL3A1	2743	0.037	0.1426	No
10	RARRES1	RARRES1	3184	0.034	0.1411	No
11	SLPI	SLPI	3427	0.032	0.1478	No
12	BACE2	BACE2	3897	0.029	0.1422	No
13	TNFAIP8	TNFAIP8	4128	0.027	0.1469	No
14	LOX	LOX	5014	0.022	0.1184	No
15	GLIPR1	GLIPR1	8258	0.009	-0.0273	No
16	MMP7	MMP7	9129	0.006	-0.0646	No
17	CDCP1	CDCP1	9398	0.005	-0.0745	No
18	RAC2	RAC2	9455	0.004	-0.0746	No
19	FTL	FTL	9543	0.004	-0.0765	No
20	COL1A2	COL1A2	9939	0.003	-0.0934	No
21	THBS1	THBS1	10919	-0.001	-0.1384	No
22	ACPP	ACPP	10996	-0.001	-0.1413	No
23	IL6	IL6	11217	-0.002	-0.1504	No
24	CD72	CD72	11460	-0.003	-0.1601	No
25	RUNX1	RUNX1	11533	-0.003	-0.1617	No
26	COL15A1	COL15A1	12559	-0.007	-0.2056	No
27	RAB27A	RAB27A	12626	-0.007	-0.2048	No
28	PTGS2	PTGS2	13295	-0.009	-0.2306	No
29	PI3	PI3	13838	-0.011	-0.2493	No
30	CAV1	CAV1	14427	-0.014	-0.2690	No
31	BNC2	BNC2	14603	-0.014	-0.2690	No
32	COL1A1	COL1A1	14878	-0.016	-0.2731	No
33	LUM	LUM	15213	-0.017	-0.2791	No
34	SPAG4	SPAG4	15315	-0.017	-0.2741	No
35	VDR	VDR	15499	-0.018	-0.2724	No
36	NNMT	NNMT	16336	-0.022	-0.2989	No
37	IL7R	IL7R	17107	-0.026	-0.3202	No
38	SYNGR2	SYNGR2	17709	-0.029	-0.3317	No
39	CTSB	CTSB	18445	-0.034	-0.3467	No
40	SDC1	SDC1	18831	-0.037	-0.3438	No
41	P4HA2	P4HA2	19472	-0.043	-0.3493	Yes
42	PLAUR	PLAUR	19606	-0.045	-0.3304	Yes
43	CTSC	CTSC	19916	-0.049	-0.3175	Yes
44	CYP1B1	CYP1B1	20518	-0.059	-0.3126	Yes
45	S100A11	S100A11	21047	-0.075	-0.2953	Yes
46	ARPC1B	ARPC1B	21177	-0.082	-0.2555	Yes
47	LY96	LY96	21395	-0.104	-0.2075	Yes
48	PRSS23	PRSS23	21462	-0.116	-0.1456	Yes
49	IER3	IER3	21480	-0.122	-0.0782	Yes
50	NDRG1	NDRG1	21524	-0.149	0.0033	Yes