Details for gene set VERHAAK_CL

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	GRD
GeneSet	VERHAAK_CL_2017
Enrichment Score (ES)	0.44006732
Normalized Enrichment Score (NES)	1.5842261
Nominal p-value	0.009746589
FDR q-value	0.01330119
FWER p-Value	0.024

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GATM	GATM	24	0.183	0.1322	Yes
2	LHFP	LHFP	243	0.095	0.1911	Yes
3	DTNA	DTNA	290	0.091	0.2556	Yes
4	PLCE1	PLCE1	500	0.078	0.3028	Yes
5	PHKB	PHKB	1025	0.060	0.3222	Yes
6	ABLIM1	ABLIM1	1755	0.048	0.3231	Yes
7	NCOA1	NCOA1	1844	0.046	0.3529	Yes
8	ZFHX4	ZFHX4	1942	0.045	0.3815	Yes
9	SOX9	SOX9	2323	0.041	0.3937	Yes
10	VAV3	VAV3	3218	0.034	0.3767	Yes
11	KIAA0494	KIAA0494	3309	0.033	0.3965	Yes
12	ACSL3	ACSL3	3718	0.030	0.3994	Yes
13	TYK2	TYK2	3910	0.029	0.4115	Yes
14	CDH4	CDH4	3939	0.029	0.4310	Yes
15	FGFR3	FGFR3	4501	0.025	0.4234	Yes
16	SLC4A4	SLC4A4	4538	0.025	0.4401	Yes
17	ZNF45	ZNF45	4974	0.023	0.4364	No
18	PTPRA	PTPRA	5269	0.021	0.4382	No
19	SLC3A2	SLC3A2	6265	0.017	0.4041	No
20	PLCG1	PLCG1	6810	0.014	0.3892	No
21	MEOX2	MEOX2	6835	0.014	0.3984	No
22	STXBP3	STXBP3	8077	0.009	0.3475	No
23	BBS1	BBS1	8334	0.008	0.3418	No
24	RBCK1	RBCK1	8828	0.007	0.3236	No
25	MLC1	MLC1	9469	0.004	0.2971	No
26	GRIK1	GRIK1	9586	0.004	0.2944	No
27	DENND2A	DENND2A	9891	0.003	0.2823	No
28	CTNND1	CTNND1	10035	0.002	0.2773	No
29	PNPLA6	PNPLA6	10054	0.002	0.2781	No
30	TJP1	TJP1	10109	0.002	0.2770	No
31	ELOVL2	ELOVL2	10475	0.001	0.2605	No
32	USP8	USP8	10618	0.000	0.2540	No
33	NPEPL1	NPEPL1	11036	-0.001	0.2356	No
34	EYA2	EYA2	11213	-0.002	0.2288	No
35	SALL1	SALL1	11657	-0.003	0.2108	No
36	PAX6	PAX6	11825	-0.004	0.2060	No
37	BCKDHB	BCKDHB	11836	-0.004	0.2085	No
38	ACSBG1	ACSBG1	12021	-0.005	0.2034	No
39	POLRMT	POLRMT	12094	-0.005	0.2037	No
40	MYO5C	MYO5C	12276	-0.006	0.1994	No
41	ARNTL	ARNTL	12633	-0.007	0.1879	No
42	UPF1	UPF1	13825	-0.011	0.1408	No
43	CST3	CST3	14040	-0.012	0.1398	No
44	SPRY2	SPRY2	16493	-0.023	0.0426	No
45	C14orf159	C14orf159	16777	-0.024	0.0471	No
46	RASGRP1	RASGRP1	17827	-0.030	0.0202	No
47	PPARGC1A	PPARGC1A	19659	-0.045	-0.0317	No
48	SLC20A2	SLC20A2	21135	-0.079	-0.0426	No
49	ZHX3	ZHX3	21264	-0.088	0.0154	No