Details for gene set VERHAAK_CL

Table: GSEA Results Summary

Dataset	NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos
Phenotype	NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in class	GRD
GeneSet	VERHAAK_CL_2010
Enrichment Score (ES)	0.28641808
Normalized Enrichment Score (NES)	1.2778009
Nominal p-value	0.05957447
FDR q-value	0.08563536
FWER p-Value	0.343

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	TBX2	TBX2	214	0.098	0.0100	Yes
2	LHFP	LHFP	243	0.095	0.0279	Yes
3	WSCD1	WSCD1	254	0.093	0.0464	Yes
4	IRS2	IRS2	302	0.090	0.0626	Yes
5	CDK6	CDK6	413	0.082	0.0741	Yes
6	FZD3	FZD3	425	0.081	0.0901	Yes
7	ZNF211	ZNF211	658	0.071	0.0936	Yes
8	PRPF31	PRPF31	659	0.071	0.1080	Yes
9	PTPN14	PTPN14	718	0.069	0.1193	Yes
10	LFNG	LFNG	759	0.067	0.1311	Yes
11	NDP	NDP	829	0.065	0.1411	Yes
12	BTBD2	BTBD2	868	0.064	0.1523	Yes
13	FZD7	FZD7	872	0.064	0.1651	Yes
14	ITGB8	ITGB8	908	0.063	0.1762	Yes
15	ANXA5	ANXA5	993	0.061	0.1846	Yes
16	GPR56	GPR56	1019	0.060	0.1957	Yes
17	SMO	SMO	1035	0.060	0.2071	Yes
18	NR2E1	NR2E1	1068	0.059	0.2177	Yes
19	RBM42	RBM42	1140	0.058	0.2262	Yes
20	RGS6	RGS6	1661	0.049	0.2119	Yes
21	ZNF671	ZNF671	1673	0.049	0.2213	Yes
22	SIPA1L1	SIPA1L1	1768	0.047	0.2265	Yes
23	DMWD	DMWD	1863	0.046	0.2315	Yes
24	KEAP1	KEAP1	1867	0.046	0.2408	Yes
25	HSPBP1	HSPBP1	1885	0.046	0.2494	Yes
26	QTRT1	QTRT1	1893	0.046	0.2584	Yes
27	ZFHX4	ZFHX4	1942	0.045	0.2654	Yes
28	DAG1	DAG1	2159	0.043	0.2640	Yes
29	KIAA0355	KIAA0355	2180	0.043	0.2717	Yes
30	GLI2	GLI2	2252	0.042	0.2769	Yes
31	SOX9	SOX9	2323	0.041	0.2819	Yes
32	ZNF304	ZNF304	2499	0.039	0.2818	Yes
33	TMEM161A	TMEM161A	2694	0.038	0.2804	Yes
34	VPS16	VPS16	3180	0.034	0.2647	Yes
35	VAV3	VAV3	3218	0.034	0.2698	Yes
36	PEPD	PEPD	3273	0.033	0.2740	Yes
37	SNTA1	SNTA1	3456	0.032	0.2719	Yes
38	EGFR	EGFR	3517	0.031	0.2755	Yes
39	CDH2	CDH2	3536	0.031	0.2810	Yes
40	PMP22	PMP22	3640	0.031	0.2824	Yes
41	ACSL3	ACSL3	3718	0.030	0.2850	Yes
42	RFXANK	RFXANK	3878	0.029	0.2834	Yes
43	CDH4	CDH4	3939	0.029	0.2864	Yes
44	CD3EAP	CD3EAP	4385	0.026	0.2709	No
45	FGFR3	FGFR3	4501	0.025	0.2707	No
46	SLC4A4	SLC4A4	4538	0.025	0.2741	No
47	POMT2	POMT2	4573	0.025	0.2776	No
48	GJA1	GJA1	4600	0.025	0.2814	No
49	LAMB2	LAMB2	4960	0.023	0.2693	No
50	ZNF45	ZNF45	4974	0.023	0.2732	No
51	ZNF235	ZNF235	4992	0.023	0.2770	No
52	TGIF2	TGIF2	5157	0.022	0.2738	No
53	PTPRA	PTPRA	5269	0.021	0.2729	No
54	KLHDC8A	KLHDC8A	5497	0.020	0.2664	No
55	RFX2	RFX2	5647	0.019	0.2634	No
56	ZNF134	ZNF134	5742	0.019	0.2628	No
57	B3GALT1	B3GALT1	6549	0.015	0.2284	No
58	MEOX2	MEOX2	6835	0.014	0.2179	No
59	LMO2	LMO2	7182	0.013	0.2044	No
60	CC2D1A	CC2D1A	7213	0.013	0.2055	No
61	GSTK1	GSTK1	7272	0.012	0.2054	No
62	SLC6A11	SLC6A11	7346	0.012	0.2044	No
63	CREB5	CREB5	7363	0.012	0.2061	No
64	TEAD3	TEAD3	7536	0.011	0.2004	No
65	DLC1	DLC1	8159	0.009	0.1732	No
66	TRIB2	TRIB2	8647	0.007	0.1520	No
67	RBCK1	RBCK1	8828	0.007	0.1449	No
68	DOCK6	DOCK6	8895	0.006	0.1431	No
69	PDGFA	PDGFA	9046	0.006	0.1373	No
70	SCAMP4	SCAMP4	9345	0.005	0.1244	No
71	ILK	ILK	9385	0.005	0.1235	No
72	MLC1	MLC1	9469	0.004	0.1205	No
73	GRIK1	GRIK1	9586	0.004	0.1158	No
74	TMED1	TMED1	9753	0.003	0.1087	No
75	PLA2G5	PLA2G5	9825	0.003	0.1060	No
76	SARS2	SARS2	9828	0.003	0.1065	No
77	DENND2A	DENND2A	9891	0.003	0.1041	No
78	RGS12	RGS12	9896	0.003	0.1045	No
79	ELOVL2	ELOVL2	10475	0.001	0.0777	No
80	NPEPL1	NPEPL1	11036	-0.001	0.0518	No
81	MAB21L1	MAB21L1	11085	-0.001	0.0499	No
82	ERCC2	ERCC2	11147	-0.002	0.0474	No
83	EYA2	EYA2	11213	-0.002	0.0447	No
84	ZNF20	ZNF20	11223	-0.002	0.0447	No
85	AKT2	AKT2	11421	-0.003	0.0360	No
86	LRP10	LRP10	11474	-0.003	0.0342	No
87	C19orf22	C19orf22	11484	-0.003	0.0344	No
88	ACSBG1	ACSBG1	12021	-0.005	0.0103	No
89	GLG1	GLG1	12198	-0.005	0.0032	No
90	MYO5C	MYO5C	12276	-0.006	0.0007	No
91	TRIP6	TRIP6	12336	-0.006	-0.0008	No
92	GNAS	GNAS	12432	-0.006	-0.0040	No
93	LRRC16	LRRC16	12465	-0.006	-0.0042	No
94	ARNTL	ARNTL	12633	-0.007	-0.0106	No
95	NR2F6	NR2F6	12640	-0.007	-0.0095	No
96	CDH6	CDH6	12859	-0.008	-0.0181	No
97	SHOX2	SHOX2	12923	-0.008	-0.0194	No
98	SOCS2	SOCS2	12965	-0.008	-0.0196	No
99	CD97	CD97	12979	-0.008	-0.0186	No
100	CENTD1	CENTD1	13241	-0.009	-0.0289	No
101	JAG1	JAG1	13262	-0.009	-0.0280	No
102	CD151	CD151	13304	-0.009	-0.0280	No
103	FBXO17	FBXO17	13319	-0.009	-0.0267	No
104	IRF3	IRF3	13414	-0.010	-0.0291	No
105	ABCD2	ABCD2	13424	-0.010	-0.0275	No
106	ZNF8	ZNF8	14099	-0.012	-0.0564	No
107	SLC2A10	SLC2A10	14204	-0.013	-0.0587	No
108	TGFB3	TGFB3	14231	-0.013	-0.0573	No
109	APBA3	APBA3	14234	-0.013	-0.0547	No
110	PIPOX	PIPOX	14260	-0.013	-0.0532	No
111	MEGF8	MEGF8	14380	-0.014	-0.0560	No
112	JUND	JUND	14460	-0.014	-0.0569	No
113	ZNF419	ZNF419	14479	-0.014	-0.0549	No
114	LRP5	LRP5	14516	-0.014	-0.0537	No
115	KLHL25	KLHL25	14523	-0.014	-0.0512	No
116	TMEM147	TMEM147	14641	-0.015	-0.0537	No
117	MEIS1	MEIS1	14829	-0.015	-0.0593	No
118	ZNF227	ZNF227	15043	-0.016	-0.0659	No
119	ZNF606	ZNF606	15137	-0.017	-0.0669	No
120	PCSK5	PCSK5	15516	-0.018	-0.0808	No
121	NES	NES	15616	-0.019	-0.0816	No
122	GRIK5	GRIK5	15628	-0.019	-0.0783	No
123	MGC2752	MGC2752	15906	-0.020	-0.0872	No
124	EXTL3	EXTL3	16028	-0.021	-0.0886	No
125	MCC	MCC	16327	-0.022	-0.0981	No
126	NPAS3	NPAS3	16347	-0.022	-0.0945	No
127	ITGA7	ITGA7	16442	-0.022	-0.0943	No
128	SPRY2	SPRY2	16493	-0.023	-0.0920	No
129	TLE2	TLE2	16986	-0.025	-0.1098	No
130	GALNT4	GALNT4	16989	-0.025	-0.1048	No
131	HS3ST3B1	HS3ST3B1	17068	-0.026	-0.1032	No
132	SLC6A9	SLC6A9	17309	-0.027	-0.1090	No
133	RASGRP1	RASGRP1	17827	-0.030	-0.1270	No
134	POFUT1	POFUT1	18272	-0.033	-0.1410	No
135	ZNF264	ZNF264	18741	-0.036	-0.1555	No
136	EPHB4	EPHB4	18748	-0.036	-0.1484	No
137	SSH3	SSH3	18771	-0.037	-0.1419	No
138	ADAM19	ADAM19	18801	-0.037	-0.1358	No
139	SEMA6D	SEMA6D	18870	-0.038	-0.1313	No
140	ZNF446	ZNF446	19404	-0.042	-0.1476	No
141	CALM1	CALM1	19460	-0.043	-0.1414	No
142	SEMA6A	SEMA6A	19784	-0.047	-0.1469	No
143	BLM	BLM	20072	-0.051	-0.1500	No
144	LRFN3	LRFN3	20177	-0.052	-0.1442	No
145	CLIP2	CLIP2	20211	-0.053	-0.1350	No
146	OSBPL3	OSBPL3	20251	-0.054	-0.1259	No
147	GAS1	GAS1	20486	-0.058	-0.1250	No
148	PRKD2	PRKD2	20637	-0.062	-0.1195	No
149	M6PRBP1	M6PRBP1	20748	-0.065	-0.1115	No
150	SLC12A4	SLC12A4	20790	-0.066	-0.1000	No
151	GNG7	GNG7	20829	-0.067	-0.0881	No
152	RIN1	RIN1	20944	-0.071	-0.0790	No
153	HMG20B	HMG20B	21026	-0.074	-0.0678	No
154	KLHL4	KLHL4	21129	-0.079	-0.0566	No
155	CAMK2B	CAMK2B	21401	-0.105	-0.0480	No
156	NOS2A	NOS2A	21431	-0.108	-0.0273	No
157	KCNF1	KCNF1	21551	-0.172	0.0021	No