Dataset | NF1_GRD_exprs.NF1_GRD_phenotype.cls #GRD_versus_Ctrl.NF1_GRD_phenotype.cls #GRD_versus_Ctrl_repos |
Phenotype | NF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos |
Upregulated in class | GRD |
GeneSet | PHILLIPS_PN |
Enrichment Score (ES) | 0.28656027 |
Normalized Enrichment Score (NES) | 1.3207374 |
Nominal p-value | 0.01968504 |
FDR q-value | 0.10328501 |
FWER p-Value | 0.259 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NTRK2 | NTRK2 | 14 | 0.225 | 0.0274 | Yes | ||
2 | GRIA2 | GRIA2 | 27 | 0.178 | 0.0491 | Yes | ||
3 | HEY2 | HEY2 | 45 | 0.155 | 0.0677 | Yes | ||
4 | PCSK1N | PCSK1N | 67 | 0.142 | 0.0844 | Yes | ||
5 | TPM1 | TPM1 | 120 | 0.116 | 0.0964 | Yes | ||
6 | TMEM100 | TMEM100 | 139 | 0.110 | 0.1094 | Yes | ||
7 | RTN1 | RTN1 | 141 | 0.110 | 0.1230 | Yes | ||
8 | SNRPN | SNRPN | 196 | 0.100 | 0.1330 | Yes | ||
9 | SEZ6L | SEZ6L | 228 | 0.096 | 0.1436 | Yes | ||
10 | WNT7B | WNT7B | 257 | 0.093 | 0.1539 | Yes | ||
11 | TIMP4 | TIMP4 | 300 | 0.090 | 0.1632 | Yes | ||
12 | FBXO2 | FBXO2 | 380 | 0.083 | 0.1699 | Yes | ||
13 | GPRC5B | GPRC5B | 412 | 0.082 | 0.1786 | Yes | ||
14 | SLIT1 | SLIT1 | 417 | 0.082 | 0.1887 | Yes | ||
15 | SOX8 | SOX8 | 446 | 0.080 | 0.1974 | Yes | ||
16 | THRA | THRA | 447 | 0.080 | 0.2074 | Yes | ||
17 | GRIA1 | GRIA1 | 461 | 0.080 | 0.2167 | Yes | ||
18 | NCAM1 | NCAM1 | 549 | 0.075 | 0.2220 | Yes | ||
19 | ATP6V1G2 | ATP6V1G2 | 568 | 0.074 | 0.2305 | Yes | ||
20 | GAD1 | GAD1 | 699 | 0.069 | 0.2330 | Yes | ||
21 | TMEM59L | TMEM59L | 704 | 0.069 | 0.2415 | Yes | ||
22 | IL17D | IL17D | 747 | 0.068 | 0.2480 | Yes | ||
23 | GAB2 | GAB2 | 865 | 0.064 | 0.2505 | Yes | ||
24 | FXYD6 | FXYD6 | 892 | 0.063 | 0.2571 | Yes | ||
25 | SLITRK5 | SLITRK5 | 1282 | 0.055 | 0.2458 | Yes | ||
26 | NUMA1 | NUMA1 | 1291 | 0.055 | 0.2522 | Yes | ||
27 | B3GAT1 | B3GAT1 | 1387 | 0.053 | 0.2544 | Yes | ||
28 | CRYAB | CRYAB | 1460 | 0.052 | 0.2574 | Yes | ||
29 | RASSF4 | RASSF4 | 1475 | 0.052 | 0.2632 | Yes | ||
30 | OLIG1 | OLIG1 | 1582 | 0.050 | 0.2645 | Yes | ||
31 | TTYH1 | TTYH1 | 1643 | 0.049 | 0.2678 | Yes | ||
32 | CCNK | CCNK | 1657 | 0.049 | 0.2733 | Yes | ||
33 | FSD1 | FSD1 | 1702 | 0.048 | 0.2773 | Yes | ||
34 | ABLIM1 | ABLIM1 | 1755 | 0.048 | 0.2809 | Yes | ||
35 | NAP1L3 | NAP1L3 | 1773 | 0.047 | 0.2860 | Yes | ||
36 | PHYHIPL | PHYHIPL | 1884 | 0.046 | 0.2866 | Yes | ||
37 | ZDHHC22 | ZDHHC22 | 2064 | 0.044 | 0.2837 | No | ||
38 | GABBR2 | GABBR2 | 2168 | 0.043 | 0.2842 | No | ||
39 | SCG3 | SCG3 | 2487 | 0.039 | 0.2742 | No | ||
40 | RAC3 | RAC3 | 2573 | 0.039 | 0.2751 | No | ||
41 | LUZP2 | LUZP2 | 2596 | 0.039 | 0.2789 | No | ||
42 | PAR5 | PAR5 | 2609 | 0.038 | 0.2831 | No | ||
43 | KIF1A | KIF1A | 2966 | 0.036 | 0.2709 | No | ||
44 | TMOD2 | TMOD2 | 2986 | 0.035 | 0.2744 | No | ||
45 | IKZF5 | IKZF5 | 3062 | 0.035 | 0.2753 | No | ||
46 | DPP10 | DPP10 | 3243 | 0.033 | 0.2710 | No | ||
47 | C1QL1 | C1QL1 | 3268 | 0.033 | 0.2740 | No | ||
48 | FLRT1 | FLRT1 | 3282 | 0.033 | 0.2775 | No | ||
49 | PLCB1 | PLCB1 | 3312 | 0.033 | 0.2803 | No | ||
50 | DUSP26 | DUSP26 | 3426 | 0.032 | 0.2790 | No | ||
51 | KCNQ5 | KCNQ5 | 3550 | 0.031 | 0.2771 | No | ||
52 | F2 | F2 | 3629 | 0.031 | 0.2773 | No | ||
53 | KCNN3 | KCNN3 | 3764 | 0.030 | 0.2747 | No | ||
54 | RIPPLY2 | RIPPLY2 | 3779 | 0.030 | 0.2778 | No | ||
55 | HSPA12A | HSPA12A | 3805 | 0.029 | 0.2802 | No | ||
56 | EPB41L2 | EPB41L2 | 3898 | 0.029 | 0.2795 | No | ||
57 | CMTM5 | CMTM5 | 4051 | 0.028 | 0.2759 | No | ||
58 | WDR86 | WDR86 | 4055 | 0.028 | 0.2792 | No | ||
59 | ZNF488 | ZNF488 | 4056 | 0.028 | 0.2827 | No | ||
60 | GNAO1 | GNAO1 | 4075 | 0.028 | 0.2853 | No | ||
61 | C11orf2 | C11orf2 | 4129 | 0.027 | 0.2863 | No | ||
62 | psiTPTE22 | psiTPTE22 | 4259 | 0.027 | 0.2836 | No | ||
63 | LRRC4 | LRRC4 | 4274 | 0.027 | 0.2862 | No | ||
64 | GRID1 | GRID1 | 4446 | 0.026 | 0.2814 | No | ||
65 | CALCRL | CALCRL | 4891 | 0.023 | 0.2635 | No | ||
66 | SEC31B | SEC31B | 5060 | 0.022 | 0.2584 | No | ||
67 | C13orf15 | C13orf15 | 5174 | 0.022 | 0.2558 | No | ||
68 | BCAN | BCAN | 5383 | 0.021 | 0.2487 | No | ||
69 | JPH3 | JPH3 | 5411 | 0.020 | 0.2500 | No | ||
70 | RASL10A | RASL10A | 5478 | 0.020 | 0.2494 | No | ||
71 | SCD | SCD | 5807 | 0.019 | 0.2364 | No | ||
72 | FAM133A | FAM133A | 6041 | 0.018 | 0.2277 | No | ||
73 | CDR1 | CDR1 | 6065 | 0.017 | 0.2288 | No | ||
74 | ADCY2 | ADCY2 | 6135 | 0.017 | 0.2277 | No | ||
75 | SGCG | SGCG | 6192 | 0.017 | 0.2272 | No | ||
76 | MMP16 | MMP16 | 6212 | 0.017 | 0.2284 | No | ||
77 | FUT9 | FUT9 | 6298 | 0.016 | 0.2265 | No | ||
78 | AKR1C1 | AKR1C1 | 6548 | 0.015 | 0.2167 | No | ||
79 | OMG | OMG | 6713 | 0.015 | 0.2109 | No | ||
80 | NRSN1 | NRSN1 | 6754 | 0.014 | 0.2108 | No | ||
81 | CYFIP2 | CYFIP2 | 6776 | 0.014 | 0.2116 | No | ||
82 | SPHKAP | SPHKAP | 6854 | 0.014 | 0.2098 | No | ||
83 | FAM19A5 | FAM19A5 | 7116 | 0.013 | 0.1992 | No | ||
84 | KSR2 | KSR2 | 7151 | 0.013 | 0.1992 | No | ||
85 | NALCN | NALCN | 7402 | 0.012 | 0.1890 | No | ||
86 | PCSK6 | PCSK6 | 7448 | 0.012 | 0.1883 | No | ||
87 | FGF14 | FGF14 | 7553 | 0.011 | 0.1849 | No | ||
88 | RAB11FIP4 | RAB11FIP4 | 8028 | 0.009 | 0.1639 | No | ||
89 | SLITRK2 | SLITRK2 | 8043 | 0.009 | 0.1644 | No | ||
90 | PLEKHB1 | PLEKHB1 | 8442 | 0.008 | 0.1468 | No | ||
91 | MPPE1 | MPPE1 | 8462 | 0.008 | 0.1469 | No | ||
92 | HLF | HLF | 8477 | 0.008 | 0.1472 | No | ||
93 | ZC3H12B | ZC3H12B | 8505 | 0.008 | 0.1469 | No | ||
94 | P2RX7 | P2RX7 | 8606 | 0.007 | 0.1431 | No | ||
95 | ABLIM3 | ABLIM3 | 8694 | 0.007 | 0.1400 | No | ||
96 | SCN3A | SCN3A | 8713 | 0.007 | 0.1400 | No | ||
97 | NET1 | NET1 | 8736 | 0.007 | 0.1398 | No | ||
98 | OVOL1 | OVOL1 | 8741 | 0.007 | 0.1405 | No | ||
99 | PHACTR3 | PHACTR3 | 8842 | 0.006 | 0.1366 | No | ||
100 | PDK2 | PDK2 | 9081 | 0.006 | 0.1262 | No | ||
101 | FAM155A | FAM155A | 9087 | 0.006 | 0.1267 | No | ||
102 | SOX6 | SOX6 | 9137 | 0.006 | 0.1251 | No | ||
103 | RASGEF1C | RASGEF1C | 9349 | 0.005 | 0.1158 | No | ||
104 | HIP1R | HIP1R | 9497 | 0.004 | 0.1094 | No | ||
105 | REPS2 | REPS2 | 9607 | 0.004 | 0.1048 | No | ||
106 | FLJ16779 | FLJ16779 | 9642 | 0.004 | 0.1036 | No | ||
107 | RPRM | RPRM | 9737 | 0.003 | 0.0996 | No | ||
108 | KIF5A | KIF5A | 9780 | 0.003 | 0.0981 | No | ||
109 | TRIM31 | TRIM31 | 9915 | 0.003 | 0.0921 | No | ||
110 | ASCL1 | ASCL1 | 10271 | 0.001 | 0.0757 | No | ||
111 | EPHB1 | EPHB1 | 10273 | 0.001 | 0.0758 | No | ||
112 | SGSM1 | SGSM1 | 10423 | 0.001 | 0.0689 | No | ||
113 | CSMD3 | CSMD3 | 10441 | 0.001 | 0.0682 | No | ||
114 | P2RY13 | P2RY13 | 10532 | 0.000 | 0.0641 | No | ||
115 | PDK4 | PDK4 | 10548 | 0.000 | 0.0634 | No | ||
116 | NKAIN4 | NKAIN4 | 10550 | 0.000 | 0.0634 | No | ||
117 | MN1 | MN1 | 10563 | 0.000 | 0.0629 | No | ||
118 | BEND7 | BEND7 | 10644 | 0.000 | 0.0592 | No | ||
119 | GNAL | GNAL | 10853 | -0.001 | 0.0495 | No | ||
120 | SORBS1 | SORBS1 | 10911 | -0.001 | 0.0469 | No | ||
121 | PKNOX2 | PKNOX2 | 11018 | -0.001 | 0.0421 | No | ||
122 | NTN4 | NTN4 | 11035 | -0.001 | 0.0415 | No | ||
123 | MAPT | MAPT | 11069 | -0.001 | 0.0402 | No | ||
124 | KCNB1 | KCNB1 | 11153 | -0.002 | 0.0365 | No | ||
125 | FGF13 | FGF13 | 11372 | -0.002 | 0.0266 | No | ||
126 | PRKCZ | PRKCZ | 11556 | -0.003 | 0.0184 | No | ||
127 | DOK6 | DOK6 | 11846 | -0.004 | 0.0054 | No | ||
128 | ARHGAP22 | ARHGAP22 | 12000 | -0.005 | -0.0012 | No | ||
129 | PSD | PSD | 12036 | -0.005 | -0.0022 | No | ||
130 | SORCS3 | SORCS3 | 12038 | -0.005 | -0.0017 | No | ||
131 | FGF12 | FGF12 | 12435 | -0.006 | -0.0194 | No | ||
132 | GRIA4 | GRIA4 | 12459 | -0.006 | -0.0197 | No | ||
133 | TMLHE | TMLHE | 12478 | -0.006 | -0.0198 | No | ||
134 | DTX4 | DTX4 | 12548 | -0.007 | -0.0222 | No | ||
135 | DLL1 | DLL1 | 12760 | -0.007 | -0.0311 | No | ||
136 | SMAD9 | SMAD9 | 12940 | -0.008 | -0.0385 | No | ||
137 | GABRA3 | GABRA3 | 12970 | -0.008 | -0.0388 | No | ||
138 | KLRC3 | KLRC3 | 13100 | -0.009 | -0.0438 | No | ||
139 | ASB13 | ASB13 | 13194 | -0.009 | -0.0470 | No | ||
140 | C12orf53 | C12orf53 | 13561 | -0.010 | -0.0629 | No | ||
141 | SNAP91 | SNAP91 | 13591 | -0.010 | -0.0629 | No | ||
142 | FERMT1 | FERMT1 | 13596 | -0.010 | -0.0618 | No | ||
143 | AJAP1 | AJAP1 | 13934 | -0.012 | -0.0761 | No | ||
144 | CRTC1 | CRTC1 | 14224 | -0.013 | -0.0880 | No | ||
145 | PDE2A | PDE2A | 14236 | -0.013 | -0.0869 | No | ||
146 | SHD | SHD | 14332 | -0.013 | -0.0897 | No | ||
147 | GABRB3 | GABRB3 | 14334 | -0.013 | -0.0881 | No | ||
148 | ZCCHC24 | ZCCHC24 | 14458 | -0.014 | -0.0921 | No | ||
149 | DLL3 | DLL3 | 14605 | -0.014 | -0.0972 | No | ||
150 | CNTN3 | CNTN3 | 14740 | -0.015 | -0.1016 | No | ||
151 | GABBR1 | GABBR1 | 14827 | -0.015 | -0.1037 | No | ||
152 | KCTD4 | KCTD4 | 14935 | -0.016 | -0.1067 | No | ||
153 | ATRNL1 | ATRNL1 | 15040 | -0.016 | -0.1096 | No | ||
154 | NDRG2 | NDRG2 | 15120 | -0.017 | -0.1112 | No | ||
155 | DSCAML1 | DSCAML1 | 15376 | -0.018 | -0.1209 | No | ||
156 | ID4 | ID4 | 15399 | -0.018 | -0.1198 | No | ||
157 | RGS9 | RGS9 | 15474 | -0.018 | -0.1210 | No | ||
158 | KIF21B | KIF21B | 15568 | -0.018 | -0.1230 | No | ||
159 | GPR158 | GPR158 | 15705 | -0.019 | -0.1270 | No | ||
160 | MCF2 | MCF2 | 15808 | -0.020 | -0.1293 | No | ||
161 | RUNDC3A | RUNDC3A | 16030 | -0.021 | -0.1371 | No | ||
162 | NEU4 | NEU4 | 16227 | -0.022 | -0.1436 | No | ||
163 | FBXL15 | FBXL15 | 16286 | -0.022 | -0.1436 | No | ||
164 | GLUD1 | GLUD1 | 16502 | -0.023 | -0.1508 | No | ||
165 | STOX1 | STOX1 | 16589 | -0.023 | -0.1519 | No | ||
166 | GFRA1 | GFRA1 | 16618 | -0.023 | -0.1503 | No | ||
167 | TPCN2 | TPCN2 | 16788 | -0.024 | -0.1552 | No | ||
168 | RIMS2 | RIMS2 | 17201 | -0.026 | -0.1712 | No | ||
169 | TAL1 | TAL1 | 17243 | -0.027 | -0.1698 | No | ||
170 | AP2B1 | AP2B1 | 17307 | -0.027 | -0.1694 | No | ||
171 | RPL13 | RPL13 | 17362 | -0.027 | -0.1685 | No | ||
172 | ELMO1 | ELMO1 | 17786 | -0.030 | -0.1846 | No | ||
173 | USH1C | USH1C | 17846 | -0.030 | -0.1837 | No | ||
174 | CNTN1 | CNTN1 | 17931 | -0.031 | -0.1838 | No | ||
175 | GLUD2 | GLUD2 | 17976 | -0.031 | -0.1820 | No | ||
176 | JPH4 | JPH4 | 18046 | -0.031 | -0.1814 | No | ||
177 | GGTA1 | GGTA1 | 18047 | -0.031 | -0.1775 | No | ||
178 | NRG3 | NRG3 | 18101 | -0.032 | -0.1760 | No | ||
179 | SLC25A21 | SLC25A21 | 18124 | -0.032 | -0.1731 | No | ||
180 | RPL37 | RPL37 | 18247 | -0.033 | -0.1747 | No | ||
181 | PID1 | PID1 | 18259 | -0.033 | -0.1712 | No | ||
182 | TNKS2 | TNKS2 | 18264 | -0.033 | -0.1673 | No | ||
183 | CBX7 | CBX7 | 18278 | -0.033 | -0.1638 | No | ||
184 | FSTL5 | FSTL5 | 18308 | -0.033 | -0.1610 | No | ||
185 | SMOC1 | SMOC1 | 18310 | -0.033 | -0.1570 | No | ||
186 | SSTR2 | SSTR2 | 18316 | -0.033 | -0.1531 | No | ||
187 | ACSM5 | ACSM5 | 18397 | -0.034 | -0.1526 | No | ||
188 | MAPK8IP2 | MAPK8IP2 | 18423 | -0.034 | -0.1495 | No | ||
189 | CSDC2 | CSDC2 | 18464 | -0.034 | -0.1472 | No | ||
190 | FRY | FRY | 18585 | -0.035 | -0.1484 | No | ||
191 | BMP2 | BMP2 | 18843 | -0.037 | -0.1558 | No | ||
192 | HDAC5 | HDAC5 | 18847 | -0.037 | -0.1512 | No | ||
193 | SH3GL2 | SH3GL2 | 18995 | -0.039 | -0.1533 | No | ||
194 | NOG | NOG | 19054 | -0.039 | -0.1511 | No | ||
195 | GRIK4 | GRIK4 | 19077 | -0.039 | -0.1473 | No | ||
196 | DNM3 | DNM3 | 19167 | -0.040 | -0.1464 | No | ||
197 | LGR5 | LGR5 | 19567 | -0.044 | -0.1595 | No | ||
198 | EFHA2 | EFHA2 | 19707 | -0.046 | -0.1603 | No | ||
199 | SLC1A1 | SLC1A1 | 19759 | -0.047 | -0.1569 | No | ||
200 | ALDH5A1 | ALDH5A1 | 19835 | -0.048 | -0.1544 | No | ||
201 | OLIG2 | OLIG2 | 19896 | -0.049 | -0.1512 | No | ||
202 | CALN1 | CALN1 | 19946 | -0.049 | -0.1474 | No | ||
203 | SSTR1 | SSTR1 | 19990 | -0.050 | -0.1432 | No | ||
204 | PKP4 | PKP4 | 20046 | -0.051 | -0.1394 | No | ||
205 | PARD3 | PARD3 | 20063 | -0.051 | -0.1339 | No | ||
206 | ENHO | ENHO | 20124 | -0.052 | -0.1302 | No | ||
207 | ANKS1B | ANKS1B | 20262 | -0.054 | -0.1299 | No | ||
208 | MAF | MAF | 20429 | -0.057 | -0.1306 | No | ||
209 | EHD3 | EHD3 | 20493 | -0.058 | -0.1263 | No | ||
210 | ZNF804A | ZNF804A | 20595 | -0.060 | -0.1235 | No | ||
211 | FAIM2 | FAIM2 | 20666 | -0.062 | -0.1190 | No | ||
212 | SUSD5 | SUSD5 | 20697 | -0.063 | -0.1125 | No | ||
213 | ARL3 | ARL3 | 20721 | -0.064 | -0.1056 | No | ||
214 | CECR6 | CECR6 | 20795 | -0.066 | -0.1008 | No | ||
215 | FAM110B | FAM110B | 20872 | -0.068 | -0.0958 | No | ||
216 | ALDOC | ALDOC | 20972 | -0.072 | -0.0915 | No | ||
217 | DSCAM | DSCAM | 20996 | -0.073 | -0.0835 | No | ||
218 | DNAJC12 | DNAJC12 | 21017 | -0.073 | -0.0753 | No | ||
219 | OPCML | OPCML | 21056 | -0.075 | -0.0677 | No | ||
220 | PTGDS | PTGDS | 21153 | -0.080 | -0.0622 | No | ||
221 | HS3ST4 | HS3ST4 | 21265 | -0.088 | -0.0565 | No | ||
222 | ABHD6 | ABHD6 | 21294 | -0.090 | -0.0466 | No | ||
223 | SLC1A4 | SLC1A4 | 21329 | -0.095 | -0.0363 | No | ||
224 | GALNT13 | GALNT13 | 21474 | -0.119 | -0.0283 | No | ||
225 | APOE | APOE | 21593 | -0.272 | 0.0001 | No |