DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classGRD
GeneSetPHILLIPS_PN
Enrichment Score (ES)0.28656027
Normalized Enrichment Score (NES)1.3207374
Nominal p-value0.01968504
FDR q-value0.10328501
FWER p-Value0.259
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_PN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NTRK2NTRK2140.2250.0274Yes
2GRIA2GRIA2270.1780.0491Yes
3HEY2HEY2450.1550.0677Yes
4PCSK1NPCSK1N670.1420.0844Yes
5TPM1TPM11200.1160.0964Yes
6TMEM100TMEM1001390.1100.1094Yes
7RTN1RTN11410.1100.1230Yes
8SNRPNSNRPN1960.1000.1330Yes
9SEZ6LSEZ6L2280.0960.1436Yes
10WNT7BWNT7B2570.0930.1539Yes
11TIMP4TIMP43000.0900.1632Yes
12FBXO2FBXO23800.0830.1699Yes
13GPRC5BGPRC5B4120.0820.1786Yes
14SLIT1SLIT14170.0820.1887Yes
15SOX8SOX84460.0800.1974Yes
16THRATHRA4470.0800.2074Yes
17GRIA1GRIA14610.0800.2167Yes
18NCAM1NCAM15490.0750.2220Yes
19ATP6V1G2ATP6V1G25680.0740.2305Yes
20GAD1GAD16990.0690.2330Yes
21TMEM59LTMEM59L7040.0690.2415Yes
22IL17DIL17D7470.0680.2480Yes
23GAB2GAB28650.0640.2505Yes
24FXYD6FXYD68920.0630.2571Yes
25SLITRK5SLITRK512820.0550.2458Yes
26NUMA1NUMA112910.0550.2522Yes
27B3GAT1B3GAT113870.0530.2544Yes
28CRYABCRYAB14600.0520.2574Yes
29RASSF4RASSF414750.0520.2632Yes
30OLIG1OLIG115820.0500.2645Yes
31TTYH1TTYH116430.0490.2678Yes
32CCNKCCNK16570.0490.2733Yes
33FSD1FSD117020.0480.2773Yes
34ABLIM1ABLIM117550.0480.2809Yes
35NAP1L3NAP1L317730.0470.2860Yes
36PHYHIPLPHYHIPL18840.0460.2866Yes
37ZDHHC22ZDHHC2220640.0440.2837No
38GABBR2GABBR221680.0430.2842No
39SCG3SCG324870.0390.2742No
40RAC3RAC325730.0390.2751No
41LUZP2LUZP225960.0390.2789No
42PAR5PAR526090.0380.2831No
43KIF1AKIF1A29660.0360.2709No
44TMOD2TMOD229860.0350.2744No
45IKZF5IKZF530620.0350.2753No
46DPP10DPP1032430.0330.2710No
47C1QL1C1QL132680.0330.2740No
48FLRT1FLRT132820.0330.2775No
49PLCB1PLCB133120.0330.2803No
50DUSP26DUSP2634260.0320.2790No
51KCNQ5KCNQ535500.0310.2771No
52F2F236290.0310.2773No
53KCNN3KCNN337640.0300.2747No
54RIPPLY2RIPPLY237790.0300.2778No
55HSPA12AHSPA12A38050.0290.2802No
56EPB41L2EPB41L238980.0290.2795No
57CMTM5CMTM540510.0280.2759No
58WDR86WDR8640550.0280.2792No
59ZNF488ZNF48840560.0280.2827No
60GNAO1GNAO140750.0280.2853No
61C11orf2C11orf241290.0270.2863No
62psiTPTE22psiTPTE2242590.0270.2836No
63LRRC4LRRC442740.0270.2862No
64GRID1GRID144460.0260.2814No
65CALCRLCALCRL48910.0230.2635No
66SEC31BSEC31B50600.0220.2584No
67C13orf15C13orf1551740.0220.2558No
68BCANBCAN53830.0210.2487No
69JPH3JPH354110.0200.2500No
70RASL10ARASL10A54780.0200.2494No
71SCDSCD58070.0190.2364No
72FAM133AFAM133A60410.0180.2277No
73CDR1CDR160650.0170.2288No
74ADCY2ADCY261350.0170.2277No
75SGCGSGCG61920.0170.2272No
76MMP16MMP1662120.0170.2284No
77FUT9FUT962980.0160.2265No
78AKR1C1AKR1C165480.0150.2167No
79OMGOMG67130.0150.2109No
80NRSN1NRSN167540.0140.2108No
81CYFIP2CYFIP267760.0140.2116No
82SPHKAPSPHKAP68540.0140.2098No
83FAM19A5FAM19A571160.0130.1992No
84KSR2KSR271510.0130.1992No
85NALCNNALCN74020.0120.1890No
86PCSK6PCSK674480.0120.1883No
87FGF14FGF1475530.0110.1849No
88RAB11FIP4RAB11FIP480280.0090.1639No
89SLITRK2SLITRK280430.0090.1644No
90PLEKHB1PLEKHB184420.0080.1468No
91MPPE1MPPE184620.0080.1469No
92HLFHLF84770.0080.1472No
93ZC3H12BZC3H12B85050.0080.1469No
94P2RX7P2RX786060.0070.1431No
95ABLIM3ABLIM386940.0070.1400No
96SCN3ASCN3A87130.0070.1400No
97NET1NET187360.0070.1398No
98OVOL1OVOL187410.0070.1405No
99PHACTR3PHACTR388420.0060.1366No
100PDK2PDK290810.0060.1262No
101FAM155AFAM155A90870.0060.1267No
102SOX6SOX691370.0060.1251No
103RASGEF1CRASGEF1C93490.0050.1158No
104HIP1RHIP1R94970.0040.1094No
105REPS2REPS296070.0040.1048No
106FLJ16779FLJ1677996420.0040.1036No
107RPRMRPRM97370.0030.0996No
108KIF5AKIF5A97800.0030.0981No
109TRIM31TRIM3199150.0030.0921No
110ASCL1ASCL1102710.0010.0757No
111EPHB1EPHB1102730.0010.0758No
112SGSM1SGSM1104230.0010.0689No
113CSMD3CSMD3104410.0010.0682No
114P2RY13P2RY13105320.0000.0641No
115PDK4PDK4105480.0000.0634No
116NKAIN4NKAIN4105500.0000.0634No
117MN1MN1105630.0000.0629No
118BEND7BEND7106440.0000.0592No
119GNALGNAL10853-0.0010.0495No
120SORBS1SORBS110911-0.0010.0469No
121PKNOX2PKNOX211018-0.0010.0421No
122NTN4NTN411035-0.0010.0415No
123MAPTMAPT11069-0.0010.0402No
124KCNB1KCNB111153-0.0020.0365No
125FGF13FGF1311372-0.0020.0266No
126PRKCZPRKCZ11556-0.0030.0184No
127DOK6DOK611846-0.0040.0054No
128ARHGAP22ARHGAP2212000-0.005-0.0012No
129PSDPSD12036-0.005-0.0022No
130SORCS3SORCS312038-0.005-0.0017No
131FGF12FGF1212435-0.006-0.0194No
132GRIA4GRIA412459-0.006-0.0197No
133TMLHETMLHE12478-0.006-0.0198No
134DTX4DTX412548-0.007-0.0222No
135DLL1DLL112760-0.007-0.0311No
136SMAD9SMAD912940-0.008-0.0385No
137GABRA3GABRA312970-0.008-0.0388No
138KLRC3KLRC313100-0.009-0.0438No
139ASB13ASB1313194-0.009-0.0470No
140C12orf53C12orf5313561-0.010-0.0629No
141SNAP91SNAP9113591-0.010-0.0629No
142FERMT1FERMT113596-0.010-0.0618No
143AJAP1AJAP113934-0.012-0.0761No
144CRTC1CRTC114224-0.013-0.0880No
145PDE2APDE2A14236-0.013-0.0869No
146SHDSHD14332-0.013-0.0897No
147GABRB3GABRB314334-0.013-0.0881No
148ZCCHC24ZCCHC2414458-0.014-0.0921No
149DLL3DLL314605-0.014-0.0972No
150CNTN3CNTN314740-0.015-0.1016No
151GABBR1GABBR114827-0.015-0.1037No
152KCTD4KCTD414935-0.016-0.1067No
153ATRNL1ATRNL115040-0.016-0.1096No
154NDRG2NDRG215120-0.017-0.1112No
155DSCAML1DSCAML115376-0.018-0.1209No
156ID4ID415399-0.018-0.1198No
157RGS9RGS915474-0.018-0.1210No
158KIF21BKIF21B15568-0.018-0.1230No
159GPR158GPR15815705-0.019-0.1270No
160MCF2MCF215808-0.020-0.1293No
161RUNDC3ARUNDC3A16030-0.021-0.1371No
162NEU4NEU416227-0.022-0.1436No
163FBXL15FBXL1516286-0.022-0.1436No
164GLUD1GLUD116502-0.023-0.1508No
165STOX1STOX116589-0.023-0.1519No
166GFRA1GFRA116618-0.023-0.1503No
167TPCN2TPCN216788-0.024-0.1552No
168RIMS2RIMS217201-0.026-0.1712No
169TAL1TAL117243-0.027-0.1698No
170AP2B1AP2B117307-0.027-0.1694No
171RPL13RPL1317362-0.027-0.1685No
172ELMO1ELMO117786-0.030-0.1846No
173USH1CUSH1C17846-0.030-0.1837No
174CNTN1CNTN117931-0.031-0.1838No
175GLUD2GLUD217976-0.031-0.1820No
176JPH4JPH418046-0.031-0.1814No
177GGTA1GGTA118047-0.031-0.1775No
178NRG3NRG318101-0.032-0.1760No
179SLC25A21SLC25A2118124-0.032-0.1731No
180RPL37RPL3718247-0.033-0.1747No
181PID1PID118259-0.033-0.1712No
182TNKS2TNKS218264-0.033-0.1673No
183CBX7CBX718278-0.033-0.1638No
184FSTL5FSTL518308-0.033-0.1610No
185SMOC1SMOC118310-0.033-0.1570No
186SSTR2SSTR218316-0.033-0.1531No
187ACSM5ACSM518397-0.034-0.1526No
188MAPK8IP2MAPK8IP218423-0.034-0.1495No
189CSDC2CSDC218464-0.034-0.1472No
190FRYFRY18585-0.035-0.1484No
191BMP2BMP218843-0.037-0.1558No
192HDAC5HDAC518847-0.037-0.1512No
193SH3GL2SH3GL218995-0.039-0.1533No
194NOGNOG19054-0.039-0.1511No
195GRIK4GRIK419077-0.039-0.1473No
196DNM3DNM319167-0.040-0.1464No
197LGR5LGR519567-0.044-0.1595No
198EFHA2EFHA219707-0.046-0.1603No
199SLC1A1SLC1A119759-0.047-0.1569No
200ALDH5A1ALDH5A119835-0.048-0.1544No
201OLIG2OLIG219896-0.049-0.1512No
202CALN1CALN119946-0.049-0.1474No
203SSTR1SSTR119990-0.050-0.1432No
204PKP4PKP420046-0.051-0.1394No
205PARD3PARD320063-0.051-0.1339No
206ENHOENHO20124-0.052-0.1302No
207ANKS1BANKS1B20262-0.054-0.1299No
208MAFMAF20429-0.057-0.1306No
209EHD3EHD320493-0.058-0.1263No
210ZNF804AZNF804A20595-0.060-0.1235No
211FAIM2FAIM220666-0.062-0.1190No
212SUSD5SUSD520697-0.063-0.1125No
213ARL3ARL320721-0.064-0.1056No
214CECR6CECR620795-0.066-0.1008No
215FAM110BFAM110B20872-0.068-0.0958No
216ALDOCALDOC20972-0.072-0.0915No
217DSCAMDSCAM20996-0.073-0.0835No
218DNAJC12DNAJC1221017-0.073-0.0753No
219OPCMLOPCML21056-0.075-0.0677No
220PTGDSPTGDS21153-0.080-0.0622No
221HS3ST4HS3ST421265-0.088-0.0565No
222ABHD6ABHD621294-0.090-0.0466No
223SLC1A4SLC1A421329-0.095-0.0363No
224GALNT13GALNT1321474-0.119-0.0283No
225APOEAPOE21593-0.2720.0001No
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_PN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_PN: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_PN