DatasetNF1_GRD_exprs.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl.NF1_GRD_phenotype.cls
#GRD_versus_Ctrl_repos
PhenotypeNF1_GRD_phenotype.cls#GRD_versus_Ctrl_repos
Upregulated in classCtrl
GeneSetPHILLIPS_MES
Enrichment Score (ES)-0.41462108
Normalized Enrichment Score (NES)-1.7690173
Nominal p-value0.0
FDR q-value8.0357137E-4
FWER p-Value0.002
Table: GSEA Results Summary



Fig 1: Enrichment plot: PHILLIPS_MES   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SLC16A3SLC16A3310.1730.0284No
2COL4A2COL4A2760.1390.0502No
3C1RC1R1080.1200.0695No
4SALL4SALL41230.1140.0885No
5FAM20CFAM20C1280.1120.1076No
6SOCS3SOCS35380.0760.1016No
7COL4A1COL4A17320.0680.1044No
8RHOJRHOJ8990.0630.1074No
9TWF1TWF19110.0620.1177No
10FLNAFLNA9330.0620.1274No
11EFEMP2EFEMP210470.0600.1324No
12ANGPTL4ANGPTL412890.0550.1306No
13OSMROSMR14570.0520.1317No
14JUNBJUNB16600.0490.1307No
15EPAS1EPAS117530.0480.1346No
16THBDTHBD17590.0480.1426No
17NRP2NRP219470.0450.1417No
18SHC1SHC120990.0440.1421No
19BCL3BCL323070.0410.1395No
20RYR3RYR324100.0400.1417No
21C15orf52C15orf5224360.0400.1473No
22ANPEPANPEP27060.0380.1413No
23PDLIM7PDLIM731620.0340.1259No
24PDGFRLPDGFRL31740.0340.1312No
25PARP10PARP1035730.0310.1180No
26ACTA2ACTA236080.0310.1217No
27FESFES36580.0300.1247No
28C1QTNF1C1QTNF137730.0300.1245No
29STEAP3STEAP337940.0290.1286No
30SLC12A9SLC12A938740.0290.1299No
31BACE2BACE238970.0290.1338No
32LPAR1LPAR139330.0290.1371No
33TPP1TPP145030.0250.1150No
34TRIM56TRIM5645050.0250.1193No
35MYL9MYL945710.0250.1205No
36FPR2FPR246760.0240.1198No
37SGSHSGSH47050.0240.1226No
38KLF16KLF1649010.0230.1175No
39GGNGGN51130.0220.1114No
40DEF6DEF655810.0200.0931No
41PVRL2PVRL259080.0180.0810No
42NRP1NRP166360.0150.0497No
43FLT1FLT168530.0140.0421No
44HK3HK372500.0120.0258No
45DLC1DLC181590.009-0.0149No
46VWA1VWA182820.009-0.0192No
47IL32IL3283060.008-0.0188No
48SHROOM3SHROOM384050.008-0.0219No
49CD248CD24884800.008-0.0240No
50PDGFAPDGFA90460.006-0.0494No
51PLA2G5PLA2G598250.003-0.0851No
52SLC39A8SLC39A8104620.001-0.1146No
53TAGLNTAGLN105740.000-0.1197No
54MAP2K3MAP2K3106000.000-0.1209No
55RRBP1RRBP110959-0.001-0.1374No
56FOSL2FOSL211178-0.002-0.1472No
57RUNX1RUNX111533-0.003-0.1632No
58CA12CA1212657-0.007-0.2143No
59SERPINA1SERPINA112892-0.008-0.2238No
60CD97CD9712979-0.008-0.2264No
61FCGR2CFCGR2C13021-0.008-0.2269No
62CECR2CECR213164-0.009-0.2320No
63ACTN1ACTN113245-0.009-0.2341No
64CD151CD15113304-0.009-0.2352No
65FAM38AFAM38A13376-0.010-0.2369No
66TRIM47TRIM4713644-0.011-0.2475No
67PI3PI313838-0.011-0.2545No
68HRH1HRH114572-0.014-0.2862No
69ANGPT2ANGPT214888-0.016-0.2982No
70LRRC32LRRC3215357-0.018-0.3170No
71TRABDTRABD15409-0.018-0.3163No
72NCLNNCLN15460-0.018-0.3155No
73ECE1ECE115587-0.019-0.3182No
74MYH9MYH915863-0.020-0.3276No
75RAB34RAB3415885-0.020-0.3251No
76GPR116GPR11616131-0.021-0.3329No
77PDPNPDPN16322-0.022-0.3380No
78ITGA7ITGA716442-0.022-0.3397No
79TNCTNC16569-0.023-0.3416No
80PMEPA1PMEPA117051-0.026-0.3596No
81ESM1ESM117075-0.026-0.3563No
82ICAM1ICAM117117-0.026-0.3537No
83LRRC29LRRC2917347-0.027-0.3597No
84C22orf26C22orf2617724-0.029-0.3722No
85SBNO2SBNO217893-0.030-0.3748No
86MVPMVP18318-0.033-0.3888No
87IFITM2IFITM218618-0.035-0.3967No
88FGGFGG18706-0.036-0.3945No
89TNFRSF10DTNFRSF10D18900-0.038-0.3970No
90HOMER3HOMER319026-0.039-0.3961No
91IFITM3IFITM319155-0.040-0.3952No
92NEURL2NEURL219573-0.044-0.4070Yes
93PLAURPLAUR19606-0.045-0.4008Yes
94C1RLC1RL19665-0.046-0.3956Yes
95UNC93B1UNC93B119712-0.046-0.3899Yes
96TTC38TTC3819716-0.046-0.3821Yes
97EMP3EMP319792-0.047-0.3775Yes
98ITGA5ITGA520099-0.051-0.3829Yes
99HSD3B7HSD3B720165-0.052-0.3770Yes
100LZTS1LZTS120169-0.052-0.3682Yes
101PTRFPTRF20222-0.053-0.3614Yes
102OSBPL3OSBPL320251-0.054-0.3535Yes
103FBN1FBN120442-0.057-0.3525Yes
104ZYXZYX20520-0.059-0.3461Yes
105PLEKHF1PLEKHF120606-0.061-0.3396Yes
106RRASRRAS20702-0.064-0.3331Yes
107SLC25A37SLC25A3720764-0.065-0.3247Yes
108FGFRL1FGFRL120784-0.066-0.3143Yes
109SERPINH1SERPINH120869-0.068-0.3065Yes
110MMP14MMP1420926-0.070-0.2970Yes
111EHD2EHD220980-0.072-0.2871Yes
112TIMP1TIMP121029-0.074-0.2766Yes
113S100A11S100A1121047-0.075-0.2646Yes
114EFNB2EFNB221255-0.087-0.2592Yes
115PAPPAPAPPA21297-0.090-0.2456Yes
116PDLIM4PDLIM421316-0.092-0.2305Yes
117SLC22A18SLC22A1821336-0.096-0.2150Yes
118LIFLIF21404-0.105-0.2000Yes
119SPOCD1SPOCD121473-0.118-0.1828Yes
120PLAUPLAU21507-0.141-0.1601Yes
121EMP1EMP121515-0.145-0.1356Yes
122SERPINE1SERPINE121554-0.173-0.1075Yes
123CHI3L1CHI3L121572-0.194-0.0750Yes
124ITGA3ITGA321577-0.205-0.0399Yes
125METTL7BMETTL7B21587-0.2360.0004Yes
Table: GSEA details [plain text format]



Fig 2: PHILLIPS_MES   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PHILLIPS_MES: Random ES distribution   
Gene set null distribution of ES for PHILLIPS_MES